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The map label for this gene is glpT [H]

Identifier: 183222434

GI number: 183222434

Start: 3196077

End: 3197396

Strand: Reverse

Name: glpT [H]

Synonym: LEPBI_I3088

Alternate gene names: 183222434

Gene position: 3197396-3196077 (Counterclockwise)

Preceding gene: 183222440

Following gene: 183222433

Centisome position: 88.82

GC content: 41.44

Gene sequence:

>1320_bases
ATGTACAAGTCCATTCGGCAGTGGTTCGCACCTGCTCCTGCGATCCCACAAAAATCAGAACAAGAGATACAATCTCTTTA
TCCTAAATTAAGATTCCAAATATTAGAATCAACTTTCATTGGTTATACGGTCTATTACCTCACTCGTAACAATTTTTCTC
CTGTCTCTAAAGAAATTGGAGAAGCATTGTCCTATACCAAATCTGACTTAGGAGACATTTTAGCTGTCACAGCCATCACG
TATGGAATTGGTAAATTTTTTATGGGAGCTTTGTCTGATCGCTCCAATCCTAGAAAATTTATGGCCGTTGGATTATTTCT
GACAGCCATTTTGAATTTTTCATTTGGATTTGCGAATCATTATTGGATCCATTTGTTTTTATGGGGTGCCAATGGACTCG
TACAAGGGATGGGTTGGCCTCCTTGTGGACGTTCCCTTGGGCATTGGTATTCTGTTCGAGAGAGGGGCACAACGTTTGCC
TTTTGGAATATTGCCCATAATATTGGAGGTGGGATTGTGGGAGTAGTCGCTTCCCACTCTGCTGCCAAGTTTGGTTGGCA
ATATGCTTTTTTTGTCCCAGGTGTCATCGCACTGTTGGGAAGTATCTATTTATACCTTCGGCTCGTAGACACTCCACAAT
CAGAAGGCCTTCCACCAGTAGAAGTGTATCGAAATGATTATCCTCCAGAAGAAAAAGAAGACCACGAAAAGGAACTCACC
ACCAAGGAATTGATCGTTGAACAGGTGTTATTAAATAAATACATTTGGTTATTTGCGATTATCAATTTTTTTGTCTACAT
CATCCGGTACAGTTTGATCGATTGGGGCCCAACCTATTTAAAAGAAACGAAGGGTGCCGATTTACTTGGAGGAGGTTACT
CCACTTTCATTTTGGAATTTGGAGGGATTGGATCCACTTTACTTATGGGTTGGGTATCCGATAAATTTGACGGTCGTCGT
GGGATGGTGAGTTTACTTTGTATCATTCCTATATTTTTTGCTTTTGTTGGAATTTTACTCAACCCACCCGGGAACATTTG
GATCGACTATTTGATGTTTGGTTTGATTGGTTTATTTATTTACCCACCTGTCATGTTGTTAGGTGTAGCAGGAATGGATT
TTACATCCAAAAAAGCAGTTGGTACAGCAGCAGGATTTATTGGACTGTTTGGGTCTCTTGGACGAACAGCCCAAGGGAAG
GGACTTGCTGTCCTTTCGACACATTACTCTTGGGATGTGGCCCTTGGTGCCATTTTGGTTTCCACTCTGATCGCAATTTT
CCTATTGATTTTCAGCTGGAATTTACGCCCCAGGGGTTAA

Upstream 100 bases:

>100_bases
GAGAGGTGTATTTCCAATCGTCGCAATAAATCCATTTCTAATTTCTGTTTGCATAAGAATACACTTGACTCCTCTCTATT
AGACTTCAATTTCCAAGTTT

Downstream 100 bases:

>100_bases
ATCAATTGACGAACCTTTGAATTTGATCCAAATTTACGAGTTATGAATCTAGGCAAAAAAATCGCAATCGGAATTATTGG
AGTCATTGCCATCCCGCTAG

Product: putative glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MYKSIRQWFAPAPAIPQKSEQEIQSLYPKLRFQILESTFIGYTVYYLTRNNFSPVSKEIGEALSYTKSDLGDILAVTAIT
YGIGKFFMGALSDRSNPRKFMAVGLFLTAILNFSFGFANHYWIHLFLWGANGLVQGMGWPPCGRSLGHWYSVRERGTTFA
FWNIAHNIGGGIVGVVASHSAAKFGWQYAFFVPGVIALLGSIYLYLRLVDTPQSEGLPPVEVYRNDYPPEEKEDHEKELT
TKELIVEQVLLNKYIWLFAIINFFVYIIRYSLIDWGPTYLKETKGADLLGGGYSTFILEFGGIGSTLLMGWVSDKFDGRR
GMVSLLCIIPIFFAFVGILLNPPGNIWIDYLMFGLIGLFIYPPVMLLGVAGMDFTSKKAVGTAAGFIGLFGSLGRTAQGK
GLAVLSTHYSWDVALGAILVSTLIAIFLLIFSWNLRPRG

Sequences:

>Translated_439_residues
MYKSIRQWFAPAPAIPQKSEQEIQSLYPKLRFQILESTFIGYTVYYLTRNNFSPVSKEIGEALSYTKSDLGDILAVTAIT
YGIGKFFMGALSDRSNPRKFMAVGLFLTAILNFSFGFANHYWIHLFLWGANGLVQGMGWPPCGRSLGHWYSVRERGTTFA
FWNIAHNIGGGIVGVVASHSAAKFGWQYAFFVPGVIALLGSIYLYLRLVDTPQSEGLPPVEVYRNDYPPEEKEDHEKELT
TKELIVEQVLLNKYIWLFAIINFFVYIIRYSLIDWGPTYLKETKGADLLGGGYSTFILEFGGIGSTLLMGWVSDKFDGRR
GMVSLLCIIPIFFAFVGILLNPPGNIWIDYLMFGLIGLFIYPPVMLLGVAGMDFTSKKAVGTAAGFIGLFGSLGRTAQGK
GLAVLSTHYSWDVALGAILVSTLIAIFLLIFSWNLRPRG
>Mature_439_residues
MYKSIRQWFAPAPAIPQKSEQEIQSLYPKLRFQILESTFIGYTVYYLTRNNFSPVSKEIGEALSYTKSDLGDILAVTAIT
YGIGKFFMGALSDRSNPRKFMAVGLFLTAILNFSFGFANHYWIHLFLWGANGLVQGMGWPPCGRSLGHWYSVRERGTTFA
FWNIAHNIGGGIVGVVASHSAAKFGWQYAFFVPGVIALLGSIYLYLRLVDTPQSEGLPPVEVYRNDYPPEEKEDHEKELT
TKELIVEQVLLNKYIWLFAIINFFVYIIRYSLIDWGPTYLKETKGADLLGGGYSTFILEFGGIGSTLLMGWVSDKFDGRR
GMVSLLCIIPIFFAFVGILLNPPGNIWIDYLMFGLIGLFIYPPVMLLGVAGMDFTSKKAVGTAAGFIGLFGSLGRTAQGK
GLAVLSTHYSWDVALGAILVSTLIAIFLLIFSWNLRPRG

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=428, Percent_Identity=27.803738317757, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI4503847, Length=428, Percent_Identity=27.803738317757, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI256219483, Length=428, Percent_Identity=27.803738317757, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI256219543, Length=449, Percent_Identity=26.9487750556793, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI256219564, Length=359, Percent_Identity=25.9052924791086, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI46361976, Length=414, Percent_Identity=23.1884057971014, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI14150047, Length=297, Percent_Identity=23.2323232323232, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38093649, Length=465, Percent_Identity=23.010752688172, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI223717983, Length=465, Percent_Identity=23.010752688172, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI49619231, Length=305, Percent_Identity=21.3114754098361, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1788573, Length=429, Percent_Identity=41.025641025641, Blast_Score=324, Evalue=6e-90,
Organism=Escherichia coli, GI87082310, Length=422, Percent_Identity=37.2037914691943, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI2367259, Length=371, Percent_Identity=32.8840970350404, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI2367379, Length=321, Percent_Identity=23.3644859813084, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082320, Length=296, Percent_Identity=22.6351351351351, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789515, Length=427, Percent_Identity=23.1850117096019, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789152, Length=415, Percent_Identity=21.4457831325301, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI133930953, Length=444, Percent_Identity=24.7747747747748, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17542316, Length=428, Percent_Identity=25.7009345794392, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17561094, Length=401, Percent_Identity=26.1845386533666, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17564202, Length=427, Percent_Identity=24.5901639344262, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI133901854, Length=464, Percent_Identity=23.0603448275862, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI133901856, Length=464, Percent_Identity=23.0603448275862, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564204, Length=356, Percent_Identity=25, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17539138, Length=309, Percent_Identity=24.9190938511327, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24656866, Length=490, Percent_Identity=23.469387755102, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45550478, Length=490, Percent_Identity=23.469387755102, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24656861, Length=464, Percent_Identity=23.9224137931034, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48900; Mature: 48900

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKSIRQWFAPAPAIPQKSEQEIQSLYPKLRFQILESTFIGYTVYYLTRNNFSPVSKEIG
CCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHH
EALSYTKSDLGDILAVTAITYGIGKFFMGALSDRSNPRKFMAVGLFLTAILNFSFGFANH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
YWIHLFLWGANGLVQGMGWPPCGRSLGHWYSVRERGTTFAFWNIAHNIGGGIVGVVASHS
EEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHCCCHHHHHHCCC
AAKFGWQYAFFVPGVIALLGSIYLYLRLVDTPQSEGLPPVEVYRNDYPPEEKEDHEKELT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHH
TKELIVEQVLLNKYIWLFAIINFFVYIIRYSLIDWGPTYLKETKGADLLGGGYSTFILEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEECCCHHHHHEEC
GGIGSTLLMGWVSDKFDGRRGMVSLLCIIPIFFAFVGILLNPPGNIWIDYLMFGLIGLFI
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YPPVMLLGVAGMDFTSKKAVGTAAGFIGLFGSLGRTAQGKGLAVLSTHYSWDVALGAILV
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHH
STLIAIFLLIFSWNLRPRG
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYKSIRQWFAPAPAIPQKSEQEIQSLYPKLRFQILESTFIGYTVYYLTRNNFSPVSKEIG
CCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHH
EALSYTKSDLGDILAVTAITYGIGKFFMGALSDRSNPRKFMAVGLFLTAILNFSFGFANH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
YWIHLFLWGANGLVQGMGWPPCGRSLGHWYSVRERGTTFAFWNIAHNIGGGIVGVVASHS
EEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHCCCHHHHHHCCC
AAKFGWQYAFFVPGVIALLGSIYLYLRLVDTPQSEGLPPVEVYRNDYPPEEKEDHEKELT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHH
TKELIVEQVLLNKYIWLFAIINFFVYIIRYSLIDWGPTYLKETKGADLLGGGYSTFILEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEECCCHHHHHEEC
GGIGSTLLMGWVSDKFDGRRGMVSLLCIIPIFFAFVGILLNPPGNIWIDYLMFGLIGLFI
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YPPVMLLGVAGMDFTSKKAVGTAAGFIGLFGSLGRTAQGKGLAVLSTHYSWDVALGAILV
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHH
STLIAIFLLIFSWNLRPRG
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]