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The map label for this gene is ygcA [C]

Identifier: 183221783

GI number: 183221783

Start: 2485759

End: 2487078

Strand: Direct

Name: ygcA [C]

Synonym: LEPBI_I2413

Alternate gene names: 183221783

Gene position: 2485759-2487078 (Clockwise)

Preceding gene: 183221781

Following gene: 183221784

Centisome position: 69.06

GC content: 39.02

Gene sequence:

>1320_bases
TTGGACAAAGTCAAAGTCGAAGGACTCAATTCCGATTTTTCGGGAATCGTCACCGCACCTAACGGAAAGAAGGTGGACAT
TTTTTTTGTTCATCCAGGTGATGAACTTGTTGTGGAATATGTCAAACGAAGGCCTCGCCAAAGGTCCTTAAAAATCCATG
AAATCATCCGAAATCACAATTGGGATTTAGTAAAATGTAATGTATTTGGAAAATGTGGAGGGTGCACGGGGCAACACATC
CCATATGAAACCCAATTAGAATTAAAATTCAAACCAATTCTAGATTCGTTCCAAAGGGATTTAGGAATATCCATAACGCC
GACCCCACAATCCAAAACCTATGCCTATCGTTCTCGTATGGACTTTTCTGTTTTCCCAGGTCCTGTGATTGGACAGAGGC
AACGAGGAAATTTTCGAAATGTGGTTCCGATCCAAGAATGTTCCATCCAATCTGATTGGGCAAACCAAGCATTACAAAAT
GTACAGACATTACTTCACAAATTTCCTGAAATCATTTGGGACAGAAGGTCGGAAGAAGGTGGACTCAAATATCTGACAAT
TCGAAAGGCACAAAATACAGATGATGGGATTCTAATTTTTACCTTCACCGATGGTTATGAAAACCATCCCAGAATGGAAA
ATTTCCGAACCGAATGTTTGGAATCATTATCGCAGGAATCCATTCTTTTCTGTTACAACCGCCCCAAATCGGAAGTCTCT
GCCGTAGGACGAGCTGAAATTTTACGAGGGAAACAAAGTTATACGGAATCTGTTCTTGGACATTTTTTTGAGGTTCCTTT
TGATTCCTTTTTCCAACCAAATCCGAATGGATTTTTACCAATTCTAAACTTCATAAAAGATTTAATCCCACAGAACCAAA
TCAATTTAATTGATTTGTTTTGTGGAAATGGATTCTTTTCTCTGTTATACGGTGATTTGTTCCAACATGTGGAAGGTTAT
GAGCTGACAGAATCTTCCATTCAAATTGCATCCAATCTTTTTTCGGAAACCTATCCTTCCAAATCACATTCCTTTCAGGT
GACCAATTTGTTTCTATCAACGGAAACTCTTTCAAAAAAAGAAAATGCGACTCTCATCCTCGACCCACCAAGAGCAGGTG
CAGGAAAACTCGTTAACCATTGGATCCGAGACTTTGGTCCTGAATTTGTATTCTATGTCTCTTGTAATCCCTACTCTCAA
AAAGAAGATGTCAGTTCATTTTTATCGGCTTATGAATATGTCGATGGAATTCTCATTGATCCATATCCACATACACCGCA
TACGGAATCGGTGCTTTTCTTTCGCAGAAAACATAGATAA

Upstream 100 bases:

>100_bases
AAGAAAAATGTAAGAGAAAACAAATAGAGAAAAGAGTCTTTTCGAAAAAACCATGTCAGAAATCCTATTCAAAAGAAAAG
GAACTGGCAAGTAGAAAACA

Downstream 100 bases:

>100_bases
AATCCCTTTACCGATTTTCTGATTCTTCCGAATAGAATAAGGAGGGAACTATGAAACAACGGACATCGATTTTATTTTTC
TGCATCGTCATTTTAGGACA

Product: putative RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MDKVKVEGLNSDFSGIVTAPNGKKVDIFFVHPGDELVVEYVKRRPRQRSLKIHEIIRNHNWDLVKCNVFGKCGGCTGQHI
PYETQLELKFKPILDSFQRDLGISITPTPQSKTYAYRSRMDFSVFPGPVIGQRQRGNFRNVVPIQECSIQSDWANQALQN
VQTLLHKFPEIIWDRRSEEGGLKYLTIRKAQNTDDGILIFTFTDGYENHPRMENFRTECLESLSQESILFCYNRPKSEVS
AVGRAEILRGKQSYTESVLGHFFEVPFDSFFQPNPNGFLPILNFIKDLIPQNQINLIDLFCGNGFFSLLYGDLFQHVEGY
ELTESSIQIASNLFSETYPSKSHSFQVTNLFLSTETLSKKENATLILDPPRAGAGKLVNHWIRDFGPEFVFYVSCNPYSQ
KEDVSSFLSAYEYVDGILIDPYPHTPHTESVLFFRRKHR

Sequences:

>Translated_439_residues
MDKVKVEGLNSDFSGIVTAPNGKKVDIFFVHPGDELVVEYVKRRPRQRSLKIHEIIRNHNWDLVKCNVFGKCGGCTGQHI
PYETQLELKFKPILDSFQRDLGISITPTPQSKTYAYRSRMDFSVFPGPVIGQRQRGNFRNVVPIQECSIQSDWANQALQN
VQTLLHKFPEIIWDRRSEEGGLKYLTIRKAQNTDDGILIFTFTDGYENHPRMENFRTECLESLSQESILFCYNRPKSEVS
AVGRAEILRGKQSYTESVLGHFFEVPFDSFFQPNPNGFLPILNFIKDLIPQNQINLIDLFCGNGFFSLLYGDLFQHVEGY
ELTESSIQIASNLFSETYPSKSHSFQVTNLFLSTETLSKKENATLILDPPRAGAGKLVNHWIRDFGPEFVFYVSCNPYSQ
KEDVSSFLSAYEYVDGILIDPYPHTPHTESVLFFRRKHR
>Mature_439_residues
MDKVKVEGLNSDFSGIVTAPNGKKVDIFFVHPGDELVVEYVKRRPRQRSLKIHEIIRNHNWDLVKCNVFGKCGGCTGQHI
PYETQLELKFKPILDSFQRDLGISITPTPQSKTYAYRSRMDFSVFPGPVIGQRQRGNFRNVVPIQECSIQSDWANQALQN
VQTLLHKFPEIIWDRRSEEGGLKYLTIRKAQNTDDGILIFTFTDGYENHPRMENFRTECLESLSQESILFCYNRPKSEVS
AVGRAEILRGKQSYTESVLGHFFEVPFDSFFQPNPNGFLPILNFIKDLIPQNQINLIDLFCGNGFFSLLYGDLFQHVEGY
ELTESSIQIASNLFSETYPSKSHSFQVTNLFLSTETLSKKENATLILDPPRAGAGKLVNHWIRDFGPEFVFYVSCNPYSQ
KEDVSSFLSAYEYVDGILIDPYPHTPHTESVLFFRRKHR

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789148, Length=451, Percent_Identity=25.9423503325942, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787083, Length=270, Percent_Identity=24.4444444444444, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322909, Length=426, Percent_Identity=25.3521126760563, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24666579, Length=389, Percent_Identity=23.1362467866324, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000072
- InterPro:   IPR010280 [H]

Pfam domain/function: PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 50428; Mature: 50428

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVKVEGLNSDFSGIVTAPNGKKVDIFFVHPGDELVVEYVKRRPRQRSLKIHEIIRNHN
CCCEEEECCCCCCCEEEECCCCCEEEEEEECCCHHHHHHHHHCCCHHHCCHHHHHHHCCC
WDLVKCNVFGKCGGCTGQHIPYETQLELKFKPILDSFQRDLGISITPTPQSKTYAYRSRM
CCEEEEEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCEECCCCCCCCCHHHHCC
DFSVFPGPVIGQRQRGNFRNVVPIQECSIQSDWANQALQNVQTLLHKFPEIIWDRRSEEG
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLKYLTIRKAQNTDDGILIFTFTDGYENHPRMENFRTECLESLSQESILFCYNRPKSEVS
CEEEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHH
AVGRAEILRGKQSYTESVLGHFFEVPFDSFFQPNPNGFLPILNFIKDLIPQNQINLIDLF
HHHHHHHHHCHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEE
CGNGFFSLLYGDLFQHVEGYELTESSIQIASNLFSETYPSKSHSFQVTNLFLSTETLSKK
ECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEHHHHCCC
ENATLILDPPRAGAGKLVNHWIRDFGPEFVFYVSCNPYSQKEDVSSFLSAYEYVDGILID
CCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEC
PYPHTPHTESVLFFRRKHR
CCCCCCCCCHHHHEEECCC
>Mature Secondary Structure
MDKVKVEGLNSDFSGIVTAPNGKKVDIFFVHPGDELVVEYVKRRPRQRSLKIHEIIRNHN
CCCEEEECCCCCCCEEEECCCCCEEEEEEECCCHHHHHHHHHCCCHHHCCHHHHHHHCCC
WDLVKCNVFGKCGGCTGQHIPYETQLELKFKPILDSFQRDLGISITPTPQSKTYAYRSRM
CCEEEEEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCEECCCCCCCCCHHHHCC
DFSVFPGPVIGQRQRGNFRNVVPIQECSIQSDWANQALQNVQTLLHKFPEIIWDRRSEEG
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLKYLTIRKAQNTDDGILIFTFTDGYENHPRMENFRTECLESLSQESILFCYNRPKSEVS
CEEEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHH
AVGRAEILRGKQSYTESVLGHFFEVPFDSFFQPNPNGFLPILNFIKDLIPQNQINLIDLF
HHHHHHHHHCHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEE
CGNGFFSLLYGDLFQHVEGYELTESSIQIASNLFSETYPSKSHSFQVTNLFLSTETLSKK
ECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEHHHHCCC
ENATLILDPPRAGAGKLVNHWIRDFGPEFVFYVSCNPYSQKEDVSSFLSAYEYVDGILID
CCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEC
PYPHTPHTESVLFFRRKHR
CCCCCCCCCHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA