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The map label for this gene is argS

Identifier: 183221471

GI number: 183221471

Start: 2183258

End: 2185042

Strand: Reverse

Name: argS

Synonym: LEPBI_I2089

Alternate gene names: 183221471

Gene position: 2185042-2183258 (Counterclockwise)

Preceding gene: 183221472

Following gene: 183221470

Centisome position: 60.7

GC content: 36.64

Gene sequence:

>1785_bases
ATGAAAGCCAATCAATTATTAAAAAATCTTGTACTCACTGAACTCGAATCGGCAGTCTCATCCTATCTTACAAAACAAAA
GATAGACCTTCCACTGACAGAATTTAAAATCCGAATCGAATACTCACGGGATGAAAAATTTGGTGATTACTCTTCGCCGT
TTGCGTTGGAAAACAAAAATATTCTAAAATTAAATCCAAAGGAAATTGCAGAAGGTGTTCTCTCCGAAATCAAAAATGAA
ACATTATTTGAATTTGTAACATTTTCTCCTCCAGGTTTTATTAATTTCCGCATCCGCTCACAGTTTTTAATCCAATATAC
AAACCAAGTCATGTCGCCTATGGTAACATTTGCCAAAACGGATGAGAAACAATCCATTTTACTGGAATTTGTTTCTGCAA
ATCCGACTGGCCCCATGAATATTGTTTCGGCACGATCCGCTGCTTATGGGGACGCTTTGGCAAATTTACTTTTAAGTCTT
GGGCATACCGTCAAACGAGAGTTTTACGTGAATGATTATGGTAACCAAGTATACTTGCTTGGAGTTGCCGTGCTCCTACG
TATCTTCGAAGAGAAAGGGGAAAAAATATCATTCCAAGAAGATGAGAGTAAGGAGTCTGTTTTTACTCTTATAGAAAAAC
GTATATTGCCAAAAGAAAGTTATCGAGGCGAATATATCAGAGATATCGCGAAGGAAGTTCTTAGTAACAAAACTAAATCA
ATTCAAGTAGAAGAGTGGATTCAAAACAAAAATTGGGATGAGTGCATTCATGATCTATCAAAATATGCAGTAGAATACAA
TTTAAGTAGGCAAAAAGAAGATTTAAAACTTTTTGGTGTTCATTTTGATCAGTTTTTCAGCGAGCGAAGTTTACACGAAG
CAGGAGATGTGGAAAATGTGCCCACTCTTTTAAAAAAAGAAGATGTATCTACCATCGATGGCAAACTACATTTTTTATCC
ACGCAGTATGGTGATGACAAAGACCGAGTGATTCGCAGAGAAGATGGCAGGCCAACGTATCTGATGGCAGACATTGCGTA
TCATTTTGACAAATACAAACGTGGATTTACTAAATTAATTGATATTTGGGGACCAGACCATTATGGATACATTGCTCGTT
TGAAAGGTGCAGTGTTATCTTTCGGGAAATCAAACGATAGTTTTTTAATTCTCATTGCCCAACAAGTGAATCTCATTGAA
AATAAAGAAAAAGTTAAGATGAGTAAACGTTTGGGAATTTTCCAAACAATGCGGGATTTGTTATCATATCTCGGAAAGAA
TGGAAAAGATGTTGGACGTTATTTTTTCTTAATGAGAAGTTCTGATGCTCCTCTCGATTTTGATTTGGACTTAGCCAAAG
ATGAGTCTGATAAAAACCCAGTATTTTATATCCAATATGCACATGCGCGGATTTGTTCCATTTTTCGTGAGTTACAAATT
TCAATAGCGGATTGGAGTATTCCAAAAGTGGTCAGCGGAGATTGTTTCCAATCGGAAGAGAGGTTGCGACTTTTGTTTTG
GGTGGCTCGATTTCAGGAAGAAGTGTATGATACTGCCACAAACTTGGAGCCACACCGCCTAACTAATTATCTACAATCAC
TCAGTAAAGCATTTACCAAATTTTATTCTCACAAGGATAATCGAATTAAAGAAAAACAAGGGGAAGAAAGGGAACAATTA
CTCTTTCTCATTTTATTCACCAAACGAGCCATCGCTTCGGGTTTGGAACTTTTGGGAATTTCAAGTCCTGAAAAAATGTC
AAAAGAAGACGAATCCAATACATGA

Upstream 100 bases:

>100_bases
CTAAGGAATCCATTCCCAATTTTGTCACACGATTCAAAATCAAAAGTTTTGAACTATGGGAAAATGCAGACCAATTAAAA
ATGGAAATACAAATAAAAAA

Downstream 100 bases:

>100_bases
CTCCTTACATTGTCATTCTATCTACAGGCTCTGAACTCACTGCAGGTAGGAGTGTGGATACAAATTCTGGATGGATTGCC
AACCAATTGTTTGAACTGGG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MKANQLLKNLVLTELESAVSSYLTKQKIDLPLTEFKIRIEYSRDEKFGDYSSPFALENKNILKLNPKEIAEGVLSEIKNE
TLFEFVTFSPPGFINFRIRSQFLIQYTNQVMSPMVTFAKTDEKQSILLEFVSANPTGPMNIVSARSAAYGDALANLLLSL
GHTVKREFYVNDYGNQVYLLGVAVLLRIFEEKGEKISFQEDESKESVFTLIEKRILPKESYRGEYIRDIAKEVLSNKTKS
IQVEEWIQNKNWDECIHDLSKYAVEYNLSRQKEDLKLFGVHFDQFFSERSLHEAGDVENVPTLLKKEDVSTIDGKLHFLS
TQYGDDKDRVIRREDGRPTYLMADIAYHFDKYKRGFTKLIDIWGPDHYGYIARLKGAVLSFGKSNDSFLILIAQQVNLIE
NKEKVKMSKRLGIFQTMRDLLSYLGKNGKDVGRYFFLMRSSDAPLDFDLDLAKDESDKNPVFYIQYAHARICSIFRELQI
SIADWSIPKVVSGDCFQSEERLRLLFWVARFQEEVYDTATNLEPHRLTNYLQSLSKAFTKFYSHKDNRIKEKQGEEREQL
LFLILFTKRAIASGLELLGISSPEKMSKEDESNT

Sequences:

>Translated_594_residues
MKANQLLKNLVLTELESAVSSYLTKQKIDLPLTEFKIRIEYSRDEKFGDYSSPFALENKNILKLNPKEIAEGVLSEIKNE
TLFEFVTFSPPGFINFRIRSQFLIQYTNQVMSPMVTFAKTDEKQSILLEFVSANPTGPMNIVSARSAAYGDALANLLLSL
GHTVKREFYVNDYGNQVYLLGVAVLLRIFEEKGEKISFQEDESKESVFTLIEKRILPKESYRGEYIRDIAKEVLSNKTKS
IQVEEWIQNKNWDECIHDLSKYAVEYNLSRQKEDLKLFGVHFDQFFSERSLHEAGDVENVPTLLKKEDVSTIDGKLHFLS
TQYGDDKDRVIRREDGRPTYLMADIAYHFDKYKRGFTKLIDIWGPDHYGYIARLKGAVLSFGKSNDSFLILIAQQVNLIE
NKEKVKMSKRLGIFQTMRDLLSYLGKNGKDVGRYFFLMRSSDAPLDFDLDLAKDESDKNPVFYIQYAHARICSIFRELQI
SIADWSIPKVVSGDCFQSEERLRLLFWVARFQEEVYDTATNLEPHRLTNYLQSLSKAFTKFYSHKDNRIKEKQGEEREQL
LFLILFTKRAIASGLELLGISSPEKMSKEDESNT
>Mature_594_residues
MKANQLLKNLVLTELESAVSSYLTKQKIDLPLTEFKIRIEYSRDEKFGDYSSPFALENKNILKLNPKEIAEGVLSEIKNE
TLFEFVTFSPPGFINFRIRSQFLIQYTNQVMSPMVTFAKTDEKQSILLEFVSANPTGPMNIVSARSAAYGDALANLLLSL
GHTVKREFYVNDYGNQVYLLGVAVLLRIFEEKGEKISFQEDESKESVFTLIEKRILPKESYRGEYIRDIAKEVLSNKTKS
IQVEEWIQNKNWDECIHDLSKYAVEYNLSRQKEDLKLFGVHFDQFFSERSLHEAGDVENVPTLLKKEDVSTIDGKLHFLS
TQYGDDKDRVIRREDGRPTYLMADIAYHFDKYKRGFTKLIDIWGPDHYGYIARLKGAVLSFGKSNDSFLILIAQQVNLIE
NKEKVKMSKRLGIFQTMRDLLSYLGKNGKDVGRYFFLMRSSDAPLDFDLDLAKDESDKNPVFYIQYAHARICSIFRELQI
SIADWSIPKVVSGDCFQSEERLRLLFWVARFQEEVYDTATNLEPHRLTNYLQSLSKAFTKFYSHKDNRIKEKQGEEREQL
LFLILFTKRAIASGLELLGISSPEKMSKEDESNT

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=621, Percent_Identity=23.0273752012882, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI15149476, Length=144, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788184, Length=143, Percent_Identity=30.0699300699301, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_LEPBA (B0SB29)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001963113.1
- ProteinModelPortal:   B0SB29
- GeneID:   6388401
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_2035
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   LBIF355278:LBF_2035-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 68754; Mature: 68754

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKANQLLKNLVLTELESAVSSYLTKQKIDLPLTEFKIRIEYSRDEKFGDYSSPFALENKN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCEECCCC
ILKLNPKEIAEGVLSEIKNETLFEFVTFSPPGFINFRIRSQFLIQYTNQVMSPMVTFAKT
EEEECHHHHHHHHHHHHCCCHHHHEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC
DEKQSILLEFVSANPTGPMNIVSARSAAYGDALANLLLSLGHTVKREFYVNDYGNQVYLL
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHEEEEECCCCEEHHH
GVAVLLRIFEEKGEKISFQEDESKESVFTLIEKRILPKESYRGEYIRDIAKEVLSNKTKS
HHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
IQVEEWIQNKNWDECIHDLSKYAVEYNLSRQKEDLKLFGVHFDQFFSERSLHEAGDVENV
EEHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHEEEEHHHHHHHHCCHHHCCCCCHH
PTLLKKEDVSTIDGKLHFLSTQYGDDKDRVIRREDGRPTYLMADIAYHFDKYKRGFTKLI
HHHHHHCCCCHHCCEEEEEECCCCCCHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
DIWGPDHYGYIARLKGAVLSFGKSNDSFLILIAQQVNLIENKEKVKMSKRLGIFQTMRDL
HHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
LSYLGKNGKDVGRYFFLMRSSDAPLDFDLDLAKDESDKNPVFYIQYAHARICSIFRELQI
HHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
SIADWSIPKVVSGDCFQSEERLRLLFWVARFQEEVYDTATNLEPHRLTNYLQSLSKAFTK
HEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FYSHKDNRIKEKQGEEREQLLFLILFTKRAIASGLELLGISSPEKMSKEDESNT
HHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHCCCCCCCC
>Mature Secondary Structure
MKANQLLKNLVLTELESAVSSYLTKQKIDLPLTEFKIRIEYSRDEKFGDYSSPFALENKN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCEECCCC
ILKLNPKEIAEGVLSEIKNETLFEFVTFSPPGFINFRIRSQFLIQYTNQVMSPMVTFAKT
EEEECHHHHHHHHHHHHCCCHHHHEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC
DEKQSILLEFVSANPTGPMNIVSARSAAYGDALANLLLSLGHTVKREFYVNDYGNQVYLL
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHEEEEECCCCEEHHH
GVAVLLRIFEEKGEKISFQEDESKESVFTLIEKRILPKESYRGEYIRDIAKEVLSNKTKS
HHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
IQVEEWIQNKNWDECIHDLSKYAVEYNLSRQKEDLKLFGVHFDQFFSERSLHEAGDVENV
EEHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHEEEEHHHHHHHHCCHHHCCCCCHH
PTLLKKEDVSTIDGKLHFLSTQYGDDKDRVIRREDGRPTYLMADIAYHFDKYKRGFTKLI
HHHHHHCCCCHHCCEEEEEECCCCCCHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
DIWGPDHYGYIARLKGAVLSFGKSNDSFLILIAQQVNLIENKEKVKMSKRLGIFQTMRDL
HHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
LSYLGKNGKDVGRYFFLMRSSDAPLDFDLDLAKDESDKNPVFYIQYAHARICSIFRELQI
HHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
SIADWSIPKVVSGDCFQSEERLRLLFWVARFQEEVYDTATNLEPHRLTNYLQSLSKAFTK
HEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FYSHKDNRIKEKQGEEREQLLFLILFTKRAIASGLELLGISSPEKMSKEDESNT
HHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA