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The map label for this gene is p20 [H]

Identifier: 183221404

GI number: 183221404

Start: 2104557

End: 2105102

Strand: Reverse

Name: p20 [H]

Synonym: LEPBI_I2022

Alternate gene names: 183221404

Gene position: 2105102-2104557 (Counterclockwise)

Preceding gene: 183221405

Following gene: 183221403

Centisome position: 58.48

GC content: 33.7

Gene sequence:

>546_bases
ATGATTTTACCAAATGAATTCTTATCAGCTGATGGACTATATTTGAGAGGATTACAACCTGAAGATGCTGCTGGAAACTA
TTTAAAATGGTTTAATGATCCTGAAGTTTGTTTTGGAAATTCGCATGGTGTTTTTCCGGTTAATCAAAAATCTTTGGTAG
AATATATCGATAATTCTTATAAATCAAACCAACAATTGGTTTTTGCAATGATCGAGAATAAAAACCACACTCACATTGGT
AATATTTCTCTGCAAGGTATCAATTGGATTAACCGAACGGCAGAATTTGCTATATTTCTCGGTGAAAAATCTTATTGGGG
CAAGGGGTTGGCAGTTCAAGCAGGAAACTTAATCGTCAATCATGGTTTTAGTGATATGAATTTAAATCGTATTTATTGTG
GTACTTTTTCTAACAATCAGGGAATGATAAAATTAGCGAAAGCATTGAAAATGACCCAAGAGGGAGTTCGTAGAAAAGCT
ATTTATAAAAATGGCATATACCTAGATATGATTGAGTTTGGCGTTTTGCGGGATGAGTTTCTTTGA

Upstream 100 bases:

>100_bases
ATGATCCCTTCGAAGGCAAAAATGTTGGTGAACCAGCCTATGATTTAAATCAAATGAAAGATCTTATTCTCAATTACCTC
AATGACCAGGATGATTCAAA

Downstream 100 bases:

>100_bases
GATTACAGATTCGTTTTAAATCAAAGTTTTATCACATTGATTGGAGTAGTTTAAAAATTTAAGCTATGAAAATACTCGCC
TTTGCTCCGCATTCATATTT

Product: putative acetyltransferase

Products: Coenzyme A; H+; N8-Acetylspermidine [C]

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MILPNEFLSADGLYLRGLQPEDAAGNYLKWFNDPEVCFGNSHGVFPVNQKSLVEYIDNSYKSNQQLVFAMIENKNHTHIG
NISLQGINWINRTAEFAIFLGEKSYWGKGLAVQAGNLIVNHGFSDMNLNRIYCGTFSNNQGMIKLAKALKMTQEGVRRKA
IYKNGIYLDMIEFGVLRDEFL

Sequences:

>Translated_181_residues
MILPNEFLSADGLYLRGLQPEDAAGNYLKWFNDPEVCFGNSHGVFPVNQKSLVEYIDNSYKSNQQLVFAMIENKNHTHIG
NISLQGINWINRTAEFAIFLGEKSYWGKGLAVQAGNLIVNHGFSDMNLNRIYCGTFSNNQGMIKLAKALKMTQEGVRRKA
IYKNGIYLDMIEFGVLRDEFL
>Mature_181_residues
MILPNEFLSADGLYLRGLQPEDAAGNYLKWFNDPEVCFGNSHGVFPVNQKSLVEYIDNSYKSNQQLVFAMIENKNHTHIG
NISLQGINWINRTAEFAIFLGEKSYWGKGLAVQAGNLIVNHGFSDMNLNRIYCGTFSNNQGMIKLAKALKMTQEGVRRKA
IYKNGIYLDMIEFGVLRDEFL

Specific function: Regulates Polyamine Concentration By Their Degradation. Acts On Spermidine, Forming N(1)- And N(8)-Acetylspermidine. [C]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: 2.3.1.57 [C]

Molecular weight: Translated: 20522; Mature: 20522

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILPNEFLSADGLYLRGLQPEDAAGNYLKWFNDPEVCFGNSHGVFPVNQKSLVEYIDNSY
CCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCEEECCCCCEEECCHHHHHHHHHCCC
KSNQQLVFAMIENKNHTHIGNISLQGINWINRTAEFAIFLGEKSYWGKGLAVQAGNLIVN
CCCCEEEEEEEECCCCEEECCEEEECCCHHCCCEEEEEEECCCCCCCCCEEEEECCEEEE
HGFSDMNLNRIYCGTFSNNQGMIKLAKALKMTQEGVRRKAIYKNGIYLDMIEFGVLRDEF
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHC
L
C
>Mature Secondary Structure
MILPNEFLSADGLYLRGLQPEDAAGNYLKWFNDPEVCFGNSHGVFPVNQKSLVEYIDNSY
CCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCEEECCCCCEEECCHHHHHHHHHCCC
KSNQQLVFAMIENKNHTHIGNISLQGINWINRTAEFAIFLGEKSYWGKGLAVQAGNLIVN
CCCCEEEEEEEECCCCEEECCEEEECCCHHCCCEEEEEEECCCCCCCCCEEEEECCEEEE
HGFSDMNLNRIYCGTFSNNQGMIKLAKALKMTQEGVRRKAIYKNGIYLDMIEFGVLRDEF
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Spermidine [C]

Specific reaction: Acetyl-CoA + Spermidine --> Coenzyme A + H+ + N8-Acetylspermidine [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2838827 [H]