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The map label for this gene is eryC1 [H]

Identifier: 183221394

GI number: 183221394

Start: 2093700

End: 2094812

Strand: Reverse

Name: eryC1 [H]

Synonym: LEPBI_I2012

Alternate gene names: 183221394

Gene position: 2094812-2093700 (Counterclockwise)

Preceding gene: 183221395

Following gene: 183221393

Centisome position: 58.19

GC content: 34.14

Gene sequence:

>1113_bases
ATGATTGAATATGAAAATTTAAAACTGCTAAATGCGCCGTTTCAAGATGAAATCAATGAGGCAATCATCCGAGTAGCAAA
GAGTGGATGGTTCATATTAGGTCAGGAATTGGAAAAATTTGAAGCCGAATTTGCAGCATTTAATGGTAACAAATATTGTA
TTGGCGTTGCCTCTGGACTAGATGCTTTGACGTTAAGTCTTAAATATTATAATTTCTCAGAGGGTATGGAGGTAATAGTT
CCCTCTAATACTTATATTGCGACTGTTTTATCTATCATTCAAAACGGACTTAAGCCAGTTTTAGTGGAACCTTCGATGGA
TACTTATAATATTGATCCTGTAAAAATAAAAGAAAAGATAACTAAGAATACTTGTGCCGTGTTGGTGGTACATCTTTATG
GTAGGCCCTGTGACATGGAGCCGATTGTAGAAATTTGTAATGTAAATAATTTAGTATTAATTGAGGATTGTGCGCAAGCA
CATGGGGCCAAATATAACCAAAAGAATGTTGGTACATTTGGTCATGTAAATGCTTTTAGTTTTTATCCCACAAAAAACTT
AGGTGCATTAGGAGATGCAGGTGCTGTTGTAACAGATGATCCGAATATCGCTGATAAAATACGAAAACTTCGAAACTATG
GTTCTTCGGTAAAATACTATAATGAATTTGTCGGAATGAATTCAAGACTAGATGAAATTCAAGCAGCAATTCTTTCGGTT
AAATTAAAACATCTTTCCAAAATCAATCAGCATAAAAAAGAACTCTTCCAAATTTACGAAACTGGATTGTCAAGCATGTT
TATCAAACCGCTACCTGATGATCATAAAATCTATCAAGTCCATCATATTTATCCAATCAGATCTTTTCATCGAGAAAAGT
TAAGAAGTTATCTATTGGATAACGGAATCAAAACAGAAATTCACTATCCAGTGCCACCTCATAAACAGAGAGCTTTAAAC
GATTATAAAACTGGAGATTGGGGTAGGGTGGTTGGTTCTTATCCAATTGCAGAAGAAATTCATGAAACGGAACTTAGTTT
GCCAATTTCTTTTATTCATTCAAAATCCGAAATCGAACGAGTTGTTGAACTTTTAAATAGGTGGCAAAATTAA

Upstream 100 bases:

>100_bases
CCTGGTTGCATTATGTTGGTATATGCTTCTGACTATTTTGATGAAGATGATTATCTCCGTCATTACGATGAATTTTTGAA
ATACATTGCCGAAAAAAGAA

Downstream 100 bases:

>100_bases
TTAATGTCCATTAATTATTATTGTACATTATTTGATACGAACTACTTGCTTCGTGCAGTTTCGATGCTCCGATCCTTGGC
TGATAAAGATCCTACGGCAA

Product: putative pyridoxal-phosphate-dependent aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MIEYENLKLLNAPFQDEINEAIIRVAKSGWFILGQELEKFEAEFAAFNGNKYCIGVASGLDALTLSLKYYNFSEGMEVIV
PSNTYIATVLSIIQNGLKPVLVEPSMDTYNIDPVKIKEKITKNTCAVLVVHLYGRPCDMEPIVEICNVNNLVLIEDCAQA
HGAKYNQKNVGTFGHVNAFSFYPTKNLGALGDAGAVVTDDPNIADKIRKLRNYGSSVKYYNEFVGMNSRLDEIQAAILSV
KLKHLSKINQHKKELFQIYETGLSSMFIKPLPDDHKIYQVHHIYPIRSFHREKLRSYLLDNGIKTEIHYPVPPHKQRALN
DYKTGDWGRVVGSYPIAEEIHETELSLPISFIHSKSEIERVVELLNRWQN

Sequences:

>Translated_370_residues
MIEYENLKLLNAPFQDEINEAIIRVAKSGWFILGQELEKFEAEFAAFNGNKYCIGVASGLDALTLSLKYYNFSEGMEVIV
PSNTYIATVLSIIQNGLKPVLVEPSMDTYNIDPVKIKEKITKNTCAVLVVHLYGRPCDMEPIVEICNVNNLVLIEDCAQA
HGAKYNQKNVGTFGHVNAFSFYPTKNLGALGDAGAVVTDDPNIADKIRKLRNYGSSVKYYNEFVGMNSRLDEIQAAILSV
KLKHLSKINQHKKELFQIYETGLSSMFIKPLPDDHKIYQVHHIYPIRSFHREKLRSYLLDNGIKTEIHYPVPPHKQRALN
DYKTGDWGRVVGSYPIAEEIHETELSLPISFIHSKSEIERVVELLNRWQN
>Mature_370_residues
MIEYENLKLLNAPFQDEINEAIIRVAKSGWFILGQELEKFEAEFAAFNGNKYCIGVASGLDALTLSLKYYNFSEGMEVIV
PSNTYIATVLSIIQNGLKPVLVEPSMDTYNIDPVKIKEKITKNTCAVLVVHLYGRPCDMEPIVEICNVNNLVLIEDCAQA
HGAKYNQKNVGTFGHVNAFSFYPTKNLGALGDAGAVVTDDPNIADKIRKLRNYGSSVKYYNEFVGMNSRLDEIQAAILSV
KLKHLSKINQHKKELFQIYETGLSSMFIKPLPDDHKIYQVHHIYPIRSFHREKLRSYLLDNGIKTEIHYPVPPHKQRALN
DYKTGDWGRVVGSYPIAEEIHETELSLPISFIHSKSEIERVVELLNRWQN

Specific function: Sensor protein that transfers the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of erythromycin biosynthesis genes (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=312, Percent_Identity=30.1282051282051, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI2367285, Length=269, Percent_Identity=29.7397769516729, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 42021; Mature: 42021

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYENLKLLNAPFQDEINEAIIRVAKSGWFILGQELEKFEAEFAAFNGNKYCIGVASGL
CCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHEECCCEEEEEECCCC
DALTLSLKYYNFSEGMEVIVPSNTYIATVLSIIQNGLKPVLVEPSMDTYNIDPVKIKEKI
CEEEEEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHH
TKNTCAVLVVHLYGRPCDMEPIVEICNVNNLVLIEDCAQAHGAKYNQKNVGTFGHVNAFS
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECHHHHCCCCCCCCCCCCCCCCCEEE
FYPTKNLGALGDAGAVVTDDPNIADKIRKLRNYGSSVKYYNEFVGMNSRLDEIQAAILSV
ECCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHH
KLKHLSKINQHKKELFQIYETGLSSMFIKPLPDDHKIYQVHHIYPIRSFHREKLRSYLLD
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHC
NGIKTEIHYPVPPHKQRALNDYKTGDWGRVVGSYPIAEEIHETELSLPISFIHSKSEIER
CCCCEEEECCCCCHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHCHHHHHH
VVELLNRWQN
HHHHHHHHCC
>Mature Secondary Structure
MIEYENLKLLNAPFQDEINEAIIRVAKSGWFILGQELEKFEAEFAAFNGNKYCIGVASGL
CCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHEECCCEEEEEECCCC
DALTLSLKYYNFSEGMEVIVPSNTYIATVLSIIQNGLKPVLVEPSMDTYNIDPVKIKEKI
CEEEEEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHH
TKNTCAVLVVHLYGRPCDMEPIVEICNVNNLVLIEDCAQAHGAKYNQKNVGTFGHVNAFS
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECHHHHCCCCCCCCCCCCCCCCCEEE
FYPTKNLGALGDAGAVVTDDPNIADKIRKLRNYGSSVKYYNEFVGMNSRLDEIQAAILSV
ECCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHH
KLKHLSKINQHKKELFQIYETGLSSMFIKPLPDDHKIYQVHHIYPIRSFHREKLRSYLLD
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHC
NGIKTEIHYPVPPHKQRALNDYKTGDWGRVVGSYPIAEEIHETELSLPISFIHSKSEIER
CCCCEEEECCCCCHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHCHHHHHH
VVELLNRWQN
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2575703 [H]