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The map label for this gene is obgE

Identifier: 183221162

GI number: 183221162

Start: 1853870

End: 1854895

Strand: Direct

Name: obgE

Synonym: LEPBI_I1776

Alternate gene names: 183221162

Gene position: 1853870-1854895 (Clockwise)

Preceding gene: 183221161

Following gene: 183221163

Centisome position: 51.5

GC content: 42.4

Gene sequence:

>1026_bases
ATGAGCGGATTTATCGACGAAGTACCCATTCAAATTCGAGCCGGACACGGAGGGGCAGGTTCTGTCCATTTCCATAAAGA
GAAATTTGTCGAATTTGGTGGCCCAGATGGTGGCGACGGTGGCAAAGGTGGCGACGTGATCTTTCTTGCGGAAGGTCGAA
TGATGACCTTGGAAAACTACCTGCCCGATCGTATGTATGCCGCACAAGACGGAGAGCCAGGTCTTGGTCAAAACCGAAAC
GGAAAAAATGGAGAAGACCTAATCCTCAAGGTTCCCGTAGGAACTCAAATCATAGATTCCGTGACGATGGAACTTATCTA
CGACTTCAATCACGACGGAGAAAGTTTTACCATTGCTACGGGCGGACGCGGCGGAAAGGGAAATACATTTTTTAAAACTT
CTGTCCAACAAGCCCCACGTTACAGCCAACCTGGCGAAGAAGGTGGTGCTTTTTCTCTCATCTTAGAATTAAAATTATTA
GCAGACATTGGCATTGTGGGTCTCCCTAACGCTGGTAAGTCGACTTTACTTGCCAAAATCACTCATGCCCATCCTAAAAT
TGCAGGGTATGCCTTCACTACTCTCTCCCCAAATCTTGGTGTTGTGCATAGACATGAAGATTTGTTTCGTTATACGGTAG
CAGACATTCCAGGGATCATAGAGGGAGCATCAAGAGGTGTGGGACTTGGGATCAGTTTTCTCAAACACATTGAACGAGTA
CAAGGGATTCTTTTTCTTTTTGACGGTGGGAATTTACAACTCGAAGAAGAATTGGAAATGTTACGAAGTGAACTTGGGAA
TTATAACCAAACACTTCTGGATAAAAAGTTTTTACTTGTGATCAATAAAATGGACATTTGGGACAATGATCCCAGTTTCA
CCGAAGAGATCCAAAAAAAATACTCTCACCTAGGTGAAATCATTTGTATCTCAGCAGATAAAGAATTCAATTTGGAATAT
TTACTCGAACGTATCGACAAAGTATTTTTTACCGAAAAAGTAAAGTTAGTTTATGAAAACACGTAA

Upstream 100 bases:

>100_bases
ATTTCCGTTTACCCGAAAGTGTAATCCTCTCCTACATTTGAGAGGACCAAACCCGTTTTAGGATTCCCTTAAACGGGTTT
TTTTTTGACCCAAGGACTAT

Downstream 100 bases:

>100_bases
GGATTTTTTAGATTCCATCCAAAAATCAAAACTCATAGTCATTAAAATTGGTAGTGCGCGGGTTTCTGGCGAAGAATCTA
AAATTAATGATTTTTTATAT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSGFIDEVPIQIRAGHGGAGSVHFHKEKFVEFGGPDGGDGGKGGDVIFLAEGRMMTLENYLPDRMYAAQDGEPGLGQNRN
GKNGEDLILKVPVGTQIIDSVTMELIYDFNHDGESFTIATGGRGGKGNTFFKTSVQQAPRYSQPGEEGGAFSLILELKLL
ADIGIVGLPNAGKSTLLAKITHAHPKIAGYAFTTLSPNLGVVHRHEDLFRYTVADIPGIIEGASRGVGLGISFLKHIERV
QGILFLFDGGNLQLEEELEMLRSELGNYNQTLLDKKFLLVINKMDIWDNDPSFTEEIQKKYSHLGEIICISADKEFNLEY
LLERIDKVFFTEKVKLVYENT

Sequences:

>Translated_341_residues
MSGFIDEVPIQIRAGHGGAGSVHFHKEKFVEFGGPDGGDGGKGGDVIFLAEGRMMTLENYLPDRMYAAQDGEPGLGQNRN
GKNGEDLILKVPVGTQIIDSVTMELIYDFNHDGESFTIATGGRGGKGNTFFKTSVQQAPRYSQPGEEGGAFSLILELKLL
ADIGIVGLPNAGKSTLLAKITHAHPKIAGYAFTTLSPNLGVVHRHEDLFRYTVADIPGIIEGASRGVGLGISFLKHIERV
QGILFLFDGGNLQLEEELEMLRSELGNYNQTLLDKKFLLVINKMDIWDNDPSFTEEIQKKYSHLGEIICISADKEFNLEY
LLERIDKVFFTEKVKLVYENT
>Mature_340_residues
SGFIDEVPIQIRAGHGGAGSVHFHKEKFVEFGGPDGGDGGKGGDVIFLAEGRMMTLENYLPDRMYAAQDGEPGLGQNRNG
KNGEDLILKVPVGTQIIDSVTMELIYDFNHDGESFTIATGGRGGKGNTFFKTSVQQAPRYSQPGEEGGAFSLILELKLLA
DIGIVGLPNAGKSTLLAKITHAHPKIAGYAFTTLSPNLGVVHRHEDLFRYTVADIPGIIEGASRGVGLGISFLKHIERVQ
GILFLFDGGNLQLEEELEMLRSELGNYNQTLLDKKFLLVINKMDIWDNDPSFTEEIQKKYSHLGEIICISADKEFNLEYL
LERIDKVFFTEKVKLVYENT

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=327, Percent_Identity=40.3669724770642, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI111955139, Length=303, Percent_Identity=35.973597359736, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI111955063, Length=137, Percent_Identity=45.2554744525547, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1789574, Length=289, Percent_Identity=46.7128027681661, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1787454, Length=129, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=334, Percent_Identity=37.7245508982036, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17552324, Length=307, Percent_Identity=32.2475570032573, Blast_Score=140, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71981008, Length=104, Percent_Identity=40.3846153846154, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=44.8453608247423, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI20129375, Length=324, Percent_Identity=39.8148148148148, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24585318, Length=295, Percent_Identity=35.9322033898305, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_LEPBA (B0S9A3)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001962808.1
- ProteinModelPortal:   B0S9A3
- SMR:   B0S9A3
- GeneID:   6388288
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_1723
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- BioCyc:   LBIF355278:LBF_1723-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 37498; Mature: 37367

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFIDEVPIQIRAGHGGAGSVHFHKEKFVEFGGPDGGDGGKGGDVIFLAEGRMMTLENY
CCCCCCCCCEEEEECCCCCCCEEECHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEHHHC
LPDRMYAAQDGEPGLGQNRNGKNGEDLILKVPVGTQIIDSVTMELIYDFNHDGESFTIAT
CCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHEEEECCCCCEEEEEE
GGRGGKGNTFFKTSVQQAPRYSQPGEEGGAFSLILELKLLADIGIVGLPNAGKSTLLAKI
CCCCCCCCCEEECCHHHCCCCCCCCCCCCEEEEEEEHHHHHHCCEEECCCCCCCHHEEEH
THAHPKIAGYAFTTLSPNLGVVHRHEDLFRYTVADIPGIIEGASRGVGLGISFLKHIERV
HHCCCCCCEEEEEECCCCCCEEECCHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHH
QGILFLFDGGNLQLEEELEMLRSELGNYNQTLLDKKFLLVINKMDIWDNDPSFTEEIQKK
CEEEEEEECCCEEEHHHHHHHHHHHCCCCHHHHCCEEEEEEEECCCCCCCCHHHHHHHHH
YSHLGEIICISADKEFNLEYLLERIDKVFFTEKVKLVYENT
HHHCCCEEEEECCCCCCHHHHHHHHHHHHHHEEEEEEEECC
>Mature Secondary Structure 
SGFIDEVPIQIRAGHGGAGSVHFHKEKFVEFGGPDGGDGGKGGDVIFLAEGRMMTLENY
CCCCCCCCEEEEECCCCCCCEEECHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEHHHC
LPDRMYAAQDGEPGLGQNRNGKNGEDLILKVPVGTQIIDSVTMELIYDFNHDGESFTIAT
CCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHEEEECCCCCEEEEEE
GGRGGKGNTFFKTSVQQAPRYSQPGEEGGAFSLILELKLLADIGIVGLPNAGKSTLLAKI
CCCCCCCCCEEECCHHHCCCCCCCCCCCCEEEEEEEHHHHHHCCEEECCCCCCCHHEEEH
THAHPKIAGYAFTTLSPNLGVVHRHEDLFRYTVADIPGIIEGASRGVGLGISFLKHIERV
HHCCCCCCEEEEEECCCCCCEEECCHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHH
QGILFLFDGGNLQLEEELEMLRSELGNYNQTLLDKKFLLVINKMDIWDNDPSFTEEIQKK
CEEEEEEECCCEEEHHHHHHHHHHHCCCCHHHHCCEEEEEEEECCCCCCCCHHHHHHHHH
YSHLGEIICISADKEFNLEYLLERIDKVFFTEKVKLVYENT
HHHCCCEEEEECCCCCCHHHHHHHHHHHHHHEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA