| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is pcrA3 [H]
Identifier: 183221122
GI number: 183221122
Start: 1810808
End: 1812802
Strand: Direct
Name: pcrA3 [H]
Synonym: LEPBI_I1736
Alternate gene names: 183221122
Gene position: 1810808-1812802 (Clockwise)
Preceding gene: 183221120
Following gene: 183221123
Centisome position: 50.3
GC content: 36.84
Gene sequence:
>1995_bases GTGGAAACGGATTTAAATGAAGCCCAAAAGCAGGTGGTTTTAGCACCAAAAGGGCCTATTTTAGTGGTTGCGGGTGCAGG GACAGGGAAAACCAAAACCTTAGTTCATCGACTGGCCCACTTGGTAAAGAATGGTACAAATCCTGAATCCATCCTTCTTT TGACCTTCACACGGCGAGCAGCAAAAGAAATGTTAGGGAGGGCTTCTCAAATTTTGGATCACCGAATGATGTCTGTTCGA GGGGGAACTTTCCATTCGTTTTGCCATTTGTTTTTACGTAAGTATGCAAATGCCCTATCTCTAGATTCTCATTTTACGAT CCTAGATGAAGAAGATACCATTGGTTTTGTGGGAATGGCAAGAGACCAAGTGGTCACAACTGGAACAAAAGTTCGATTCC CCAAAAAAGAAACACTGGCAGAAATCTTTTCTTCTTGTTTTAACTTACAAGTCTCACTCGAAAAATACTTACAAAAAGAA TACCCAATGTTTCTTGGAATCACAAAAGAAATCCAAGAAATCAAAACAAAGTTTAGTGATCTGAAATTAAAACACAACTC TCTTGATTTTGATGATTTATTAGACTTCACTCGAAAATTATTGATGTCAGATGAATCCATTCGTGAGCGAATGTCTTCTG TTTATGAATACATTTTAGTAGATGAATACCAAGATACGAATCGTATCCAAGCTCATATCGCTTGTTTACTTGCAAGTAAA CACCAAAACATTTTGGTTGTAGGTGACGATGCTCAATGCATCTACGGATTTCGAGGTGCTAGTGTTCACAATATGTTGGA TTTTCCCAAAATTTTTCCGAACACAAATACCATCCAACTGACCAAAAATTACCGAAGTGTTCAGCCGATTCTGAATCTTG CAAATGCTGTTTTAGAAAAGAGTTCTGAGAATTACAAAAAAAATCTTGTATCCGCTTTTCCTAAAAATTCCAAGAATCCT TACTTAGTACAACTTCCGTCTTTGGAAGAAGAAGCGGAATGGACAAGCAATCAAATTTTGGAACTCTATGAGGAAGGGAT AACTTTGTCAGAAATGGCAGTTTTGTTTCGTGCTGGTTTTTCATCCCACCTACTCGAAGTTCAACTAAACTCCAAAAAAA TTCCATATCGGAAATATGGTGGAAGGCGATTTTTTGATTTGGCCCATGTGAAAGACATGATCGCCTATTTAAAGATCATT GAAAATCCAAAAGATATTTTGTCTTGGAACCGAATTTTACTATTAGAAGATCAGATCGGAAAAAAATATTCGATTCTTTT ATTCAAAAAATTAGAATCCAATCAATTCCAATGGAAAGACGATGAACATTTTTTCCTAGGATTACCTGAGACGACAAAGG ATTCTTTCTTGAAACTCATGCACTGTTTGGATTCTGTATCACCTGTCATTCATTCCACACAACAAATTCTCGAACGTATC CTTGCCTATTATTTTCCTCTTTTGGAATCCAACTACGATGATGCAGAAAAACGAAAACAAGACCTTGATGCATTGGTTCT TTTATCCAAACAGGAACCAAAATTATCTGATTATTTATCCAACCTAATCTTAAATCCTGTGGAAGGAAAAGAAATCGGAA CTTCCAATGAGGTGGAGGATGAGTTTCTCACCTTATCCACCATCCATTCTGCAAAAGGATTGGAATGGAAGTATGTGTTT ACCTTGCAAGTAGTAGAAGGAAATTTACCACATAGCCGCATTCGTACGACAGATGAATTGGAAGAAGAAAGACGTTTGTT TTATGTGGCAATTACGAGAGCAAAAGAAGCCCTTTTTCTTACAAATCCAGCCTTTAACGACAAAAATCGATTTACGCCCG TTAGTCGTTTTTTATCGGACTTACCAAAAGAAAATCAATTATTACAATTTTTAGATCCCAAAAATGCACAAAGTCCAAAA GAAATCCCAAAGGATGGCCAAAAAGAGCCTTCAAACGAAACCTTCCAAAACATACAAAACTACTTTTTGAATTGA
Upstream 100 bases:
>100_bases TTTCCCACAATTGATGTCATCGTTTTACAAAACCAGTCCACACAATCAAACAGAATAATTTCCGTTTGTCAACAGAATCC AGACAACAAATCTCTGTATT
Downstream 100 bases:
>100_bases TTTTTCTCCAAACACTGTAGAAAATCAAAGGCATTGGGGGAATTATGAAGAACCATTACCAAACCATAATCATCAGTTCA CTATCGTTATTATTATCCTT
Product: ATP-dependent DNA helicase PcrA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 664; Mature: 664
Protein sequence:
>664_residues METDLNEAQKQVVLAPKGPILVVAGAGTGKTKTLVHRLAHLVKNGTNPESILLLTFTRRAAKEMLGRASQILDHRMMSVR GGTFHSFCHLFLRKYANALSLDSHFTILDEEDTIGFVGMARDQVVTTGTKVRFPKKETLAEIFSSCFNLQVSLEKYLQKE YPMFLGITKEIQEIKTKFSDLKLKHNSLDFDDLLDFTRKLLMSDESIRERMSSVYEYILVDEYQDTNRIQAHIACLLASK HQNILVVGDDAQCIYGFRGASVHNMLDFPKIFPNTNTIQLTKNYRSVQPILNLANAVLEKSSENYKKNLVSAFPKNSKNP YLVQLPSLEEEAEWTSNQILELYEEGITLSEMAVLFRAGFSSHLLEVQLNSKKIPYRKYGGRRFFDLAHVKDMIAYLKII ENPKDILSWNRILLLEDQIGKKYSILLFKKLESNQFQWKDDEHFFLGLPETTKDSFLKLMHCLDSVSPVIHSTQQILERI LAYYFPLLESNYDDAEKRKQDLDALVLLSKQEPKLSDYLSNLILNPVEGKEIGTSNEVEDEFLTLSTIHSAKGLEWKYVF TLQVVEGNLPHSRIRTTDELEEERRLFYVAITRAKEALFLTNPAFNDKNRFTPVSRFLSDLPKENQLLQFLDPKNAQSPK EIPKDGQKEPSNETFQNIQNYFLN
Sequences:
>Translated_664_residues METDLNEAQKQVVLAPKGPILVVAGAGTGKTKTLVHRLAHLVKNGTNPESILLLTFTRRAAKEMLGRASQILDHRMMSVR GGTFHSFCHLFLRKYANALSLDSHFTILDEEDTIGFVGMARDQVVTTGTKVRFPKKETLAEIFSSCFNLQVSLEKYLQKE YPMFLGITKEIQEIKTKFSDLKLKHNSLDFDDLLDFTRKLLMSDESIRERMSSVYEYILVDEYQDTNRIQAHIACLLASK HQNILVVGDDAQCIYGFRGASVHNMLDFPKIFPNTNTIQLTKNYRSVQPILNLANAVLEKSSENYKKNLVSAFPKNSKNP YLVQLPSLEEEAEWTSNQILELYEEGITLSEMAVLFRAGFSSHLLEVQLNSKKIPYRKYGGRRFFDLAHVKDMIAYLKII ENPKDILSWNRILLLEDQIGKKYSILLFKKLESNQFQWKDDEHFFLGLPETTKDSFLKLMHCLDSVSPVIHSTQQILERI LAYYFPLLESNYDDAEKRKQDLDALVLLSKQEPKLSDYLSNLILNPVEGKEIGTSNEVEDEFLTLSTIHSAKGLEWKYVF TLQVVEGNLPHSRIRTTDELEEERRLFYVAITRAKEALFLTNPAFNDKNRFTPVSRFLSDLPKENQLLQFLDPKNAQSPK EIPKDGQKEPSNETFQNIQNYFLN >Mature_664_residues METDLNEAQKQVVLAPKGPILVVAGAGTGKTKTLVHRLAHLVKNGTNPESILLLTFTRRAAKEMLGRASQILDHRMMSVR GGTFHSFCHLFLRKYANALSLDSHFTILDEEDTIGFVGMARDQVVTTGTKVRFPKKETLAEIFSSCFNLQVSLEKYLQKE YPMFLGITKEIQEIKTKFSDLKLKHNSLDFDDLLDFTRKLLMSDESIRERMSSVYEYILVDEYQDTNRIQAHIACLLASK HQNILVVGDDAQCIYGFRGASVHNMLDFPKIFPNTNTIQLTKNYRSVQPILNLANAVLEKSSENYKKNLVSAFPKNSKNP YLVQLPSLEEEAEWTSNQILELYEEGITLSEMAVLFRAGFSSHLLEVQLNSKKIPYRKYGGRRFFDLAHVKDMIAYLKII ENPKDILSWNRILLLEDQIGKKYSILLFKKLESNQFQWKDDEHFFLGLPETTKDSFLKLMHCLDSVSPVIHSTQQILERI LAYYFPLLESNYDDAEKRKQDLDALVLLSKQEPKLSDYLSNLILNPVEGKEIGTSNEVEDEFLTLSTIHSAKGLEWKYVF TLQVVEGNLPHSRIRTTDELEEERRLFYVAITRAKEALFLTNPAFNDKNRFTPVSRFLSDLPKENQLLQFLDPKNAQSPK EIPKDGQKEPSNETFQNIQNYFLN
Specific function: Essential helicase [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI2367296, Length=647, Percent_Identity=30.4482225656878, Blast_Score=256, Evalue=2e-69, Organism=Escherichia coli, GI48994965, Length=679, Percent_Identity=29.0132547864507, Blast_Score=226, Evalue=3e-60, Organism=Saccharomyces cerevisiae, GI6322369, Length=421, Percent_Identity=30.6413301662708, Blast_Score=145, Evalue=2e-35, Organism=Saccharomyces cerevisiae, GI6324477, Length=385, Percent_Identity=24.9350649350649, Blast_Score=82, Evalue=3e-16,
Paralogues:
None
Copy number: 3000 [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005751 - InterPro: IPR013986 - InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 76365; Mature: 76365
Theoretical pI: Translated: 6.77; Mature: 6.77
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure METDLNEAQKQVVLAPKGPILVVAGAGTGKTKTLVHRLAHLVKNGTNPESILLLTFTRRA CCCCCCHHHHEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHH AKEMLGRASQILDHRMMSVRGGTFHSFCHLFLRKYANALSLDSHFTILDEEDTIGFVGMA HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEC RDQVVTTGTKVRFPKKETLAEIFSSCFNLQVSLEKYLQKEYPMFLGITKEIQEIKTKFSD CCCEEECCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCEEECHHHHHHHHHHHHHH LKLKHNSLDFDDLLDFTRKLLMSDESIRERMSSVYEYILVDEYQDTNRIQAHIACLLASK CEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC HQNILVVGDDAQCIYGFRGASVHNMLDFPKIFPNTNTIQLTKNYRSVQPILNLANAVLEK CCCEEEEECCCCEEEECCCCCHHHHHCCHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHC SSENYKKNLVSAFPKNSKNPYLVQLPSLEEEAEWTSNQILELYEEGITLSEMAVLFRAGF CCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC SSHLLEVQLNSKKIPYRKYGGRRFFDLAHVKDMIAYLKIIENPKDILSWNRILLLEDQIG CCCEEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCC KKYSILLFKKLESNQFQWKDDEHFFLGLPETTKDSFLKLMHCLDSVSPVIHSTQQILERI CEEEEEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH LAYYFPLLESNYDDAEKRKQDLDALVLLSKQEPKLSDYLSNLILNPVEGKEIGTSNEVED HHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHH EFLTLSTIHSAKGLEWKYVFTLQVVEGNLPHSRIRTTDELEEERRLFYVAITRAKEALFL HHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHCCCHHHHHHHHEEEEEEEECCCCEEEE TNPAFNDKNRFTPVSRFLSDLPKENQLLQFLDPKNAQSPKEIPKDGQKEPSNETFQNIQN ECCCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCHHCCCCCCCCCCHHHHHHHHH YFLN HHCC >Mature Secondary Structure METDLNEAQKQVVLAPKGPILVVAGAGTGKTKTLVHRLAHLVKNGTNPESILLLTFTRRA CCCCCCHHHHEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHH AKEMLGRASQILDHRMMSVRGGTFHSFCHLFLRKYANALSLDSHFTILDEEDTIGFVGMA HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEC RDQVVTTGTKVRFPKKETLAEIFSSCFNLQVSLEKYLQKEYPMFLGITKEIQEIKTKFSD CCCEEECCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCEEECHHHHHHHHHHHHHH LKLKHNSLDFDDLLDFTRKLLMSDESIRERMSSVYEYILVDEYQDTNRIQAHIACLLASK CEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC HQNILVVGDDAQCIYGFRGASVHNMLDFPKIFPNTNTIQLTKNYRSVQPILNLANAVLEK CCCEEEEECCCCEEEECCCCCHHHHHCCHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHC SSENYKKNLVSAFPKNSKNPYLVQLPSLEEEAEWTSNQILELYEEGITLSEMAVLFRAGF CCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC SSHLLEVQLNSKKIPYRKYGGRRFFDLAHVKDMIAYLKIIENPKDILSWNRILLLEDQIG CCCEEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCC KKYSILLFKKLESNQFQWKDDEHFFLGLPETTKDSFLKLMHCLDSVSPVIHSTQQILERI CEEEEEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH LAYYFPLLESNYDDAEKRKQDLDALVLLSKQEPKLSDYLSNLILNPVEGKEIGTSNEVED HHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHH EFLTLSTIHSAKGLEWKYVFTLQVVEGNLPHSRIRTTDELEEERRLFYVAITRAKEALFL HHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHCCCHHHHHHHHEEEEEEEECCCCEEEE TNPAFNDKNRFTPVSRFLSDLPKENQLLQFLDPKNAQSPKEIPKDGQKEPSNETFQNIQN ECCCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCHHCCCCCCCCCCHHHHHHHHH YFLN HHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA