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The map label for this gene is rnhB [H]

Identifier: 183221052

GI number: 183221052

Start: 1738756

End: 1739220

Strand: Direct

Name: rnhB [H]

Synonym: LEPBI_I1665

Alternate gene names: 183221052

Gene position: 1738756-1739220 (Clockwise)

Preceding gene: 183221051

Following gene: 183221053

Centisome position: 48.3

GC content: 43.87

Gene sequence:

>465_bases
GTGAGTGCAAAGTTTATTGACAGGTTCAATATCAACCAAGCCATCTTTTATGGGATCAGTCGTGCATTGCCTGTGAATCC
AAGACAAGTGACTGGTCATCTTCACAAAACTGGAATCCCGCTGGGAACACAAACAAAGGAAACTCTCGCCCCCTTTCTAT
TCGTAGATGGAAATTACAAATTAAAGATCCACAAACCCATTGAGGGATACCTTTCGATTCCCAAAGGGGATGATTTGGTC
CCATCGATTTCCGCAGCTTCGATCCTTGCGAAAACCTACCGAGATGAATACATGGAAAAAATGGATGCCAAATACCCTGG
CTATGGATTTGCCAAACACAAAGGGTATGGAACCGAAGAACACCGGGAAGCACTTCGAAAATTGGGAATTTCTCCGATCC
ATAGGTTGAGTTTTTGCAATTTTCTCCGAAGGGAAGGGAGTGAACCCTCTCTTTTTCCACTCTAA

Upstream 100 bases:

>100_bases
CTTAAAAAACCTTCGCGACTCTAAAAAAATCCCCGAACCCAAACGATTCGAACTCCGAACCGAAATTTTACAATACGCTG
CGTATTGGCATGTAAGCTTT

Downstream 100 bases:

>100_bases
TCCTTTCGGAAACTCAAACCCTCCTTTCTTCCAGTCCTTTGGAAAACGATCTCCTTCGAACCAAGAATTCAAAGATGGTA
TGGATTTGTCTTTTTCGAAG

Product: putative ribonuclease H

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSAKFIDRFNINQAIFYGISRALPVNPRQVTGHLHKTGIPLGTQTKETLAPFLFVDGNYKLKIHKPIEGYLSIPKGDDLV
PSISAASILAKTYRDEYMEKMDAKYPGYGFAKHKGYGTEEHREALRKLGISPIHRLSFCNFLRREGSEPSLFPL

Sequences:

>Translated_154_residues
MSAKFIDRFNINQAIFYGISRALPVNPRQVTGHLHKTGIPLGTQTKETLAPFLFVDGNYKLKIHKPIEGYLSIPKGDDLV
PSISAASILAKTYRDEYMEKMDAKYPGYGFAKHKGYGTEEHREALRKLGISPIHRLSFCNFLRREGSEPSLFPL
>Mature_153_residues
SAKFIDRFNINQAIFYGISRALPVNPRQVTGHLHKTGIPLGTQTKETLAPFLFVDGNYKLKIHKPIEGYLSIPKGDDLVP
SISAASILAKTYRDEYMEKMDAKYPGYGFAKHKGYGTEEHREALRKLGISPIHRLSFCNFLRREGSEPSLFPL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=142, Percent_Identity=39.4366197183099, Blast_Score=77, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 17398; Mature: 17267

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKFIDRFNINQAIFYGISRALPVNPRQVTGHLHKTGIPLGTQTKETLAPFLFVDGNYK
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCHHHHCCCCCCCCCHHHHCCEEEECCCEE
LKIHKPIEGYLSIPKGDDLVPSISAASILAKTYRDEYMEKMDAKYPGYGFAKHKGYGTEE
EEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
HREALRKLGISPIHRLSFCNFLRREGSEPSLFPL
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SAKFIDRFNINQAIFYGISRALPVNPRQVTGHLHKTGIPLGTQTKETLAPFLFVDGNYK
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCHHHHCCCCCCCCCHHHHCCEEEECCCEE
LKIHKPIEGYLSIPKGDDLVPSISAASILAKTYRDEYMEKMDAKYPGYGFAKHKGYGTEE
EEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
HREALRKLGISPIHRLSFCNFLRREGSEPSLFPL
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA