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The map label for this gene is fadB1 [C]

Identifier: 183220771

GI number: 183220771

Start: 1438974

End: 1439807

Strand: Reverse

Name: fadB1 [C]

Synonym: LEPBI_I1382

Alternate gene names: 183220771

Gene position: 1439807-1438974 (Counterclockwise)

Preceding gene: 183220772

Following gene: 183220769

Centisome position: 40.0

GC content: 43.41

Gene sequence:

>834_bases
ATGAATCCATCTCCATTTTTTACCATCGAAAGAAGAAAAAACGTCGCCATCCTTTGGTTGAATCGTCCTGAAAAACGAAA
TGCCATGAACTGGCCTTTTTGGCGTGACCTTCCGGATATGGTGGCAGAGATTGATGCTGATCCGAAAATCCATGCATTTG
TGATCGCAGGCAAAGGAAAATCTTTTTCGACAGGACTTGATTTGGAGGAATTTTTCCAAGACTTCAAACCCGTCGTCCAA
GGGGAATTCGCAGATGGTCGAGAAAAACTTTACCAACTCATTCTCACGATGCAAAAAGGAATCAACGCTGTTTACAATTC
CAAAAAACCATCGATTGCACTAGTTCAAAAACATTGTATCGGTGGAGGACTGGATTTGGTATCAGCCTGTGACATTCGGT
ATGCATCTGACGACGCTGTATTTTCCTTACGTGAATCCAAAGTCGCCATCGTTGCCGACATGGGATCCTTACAAAGACTC
CCCCATTTGATTGGAAATGCACATACAAGAGAGCTTGCCCTCACGGGAAAAGACGTTACGGCAAATGAAGCCTTTCAAAT
GGGACTTGTGACAAAGGTCACAAAAGACTTTGATTCTTTATTGGTAGAAGGTCTCAAAACGGCGAATGAAATAGCTGAAA
ATCCAACAATTGTAATCCGAGGCGTCAAACAAGTGCTAAATCATGGAGTAGGAAAAACCATTGAAGAAGGTTTGGACTAC
GTGGCGGTTTGGAATGCAAGTATGCTCGATTCCAAAGATTTCCGAAGTGCCATCGGTGGGTTTATGGAACGAAAACGACC
TGTCTTCAATCCAGAAACCCGAGTGGACGATTGA

Upstream 100 bases:

>100_bases
ATGGATTTTCACAATCACAGTACATCTCCATTGCTCTCATACTCTTTGGTGTTTATTTGATGGTCTCCAAAAAACTTTGG
TTAAAGGAAGAGGGAAAGGT

Downstream 100 bases:

>100_bases
GACCCAATCGTTTAACAATAAATGTCGAGTAACCTTTCGCTTTTTGCCACAGGACCCAGTTTTTCTTCCACTGCCAACTT
CATCAGTTTTTCAGTCAGTT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MNPSPFFTIERRKNVAILWLNRPEKRNAMNWPFWRDLPDMVAEIDADPKIHAFVIAGKGKSFSTGLDLEEFFQDFKPVVQ
GEFADGREKLYQLILTMQKGINAVYNSKKPSIALVQKHCIGGGLDLVSACDIRYASDDAVFSLRESKVAIVADMGSLQRL
PHLIGNAHTRELALTGKDVTANEAFQMGLVTKVTKDFDSLLVEGLKTANEIAENPTIVIRGVKQVLNHGVGKTIEEGLDY
VAVWNASMLDSKDFRSAIGGFMERKRPVFNPETRVDD

Sequences:

>Translated_277_residues
MNPSPFFTIERRKNVAILWLNRPEKRNAMNWPFWRDLPDMVAEIDADPKIHAFVIAGKGKSFSTGLDLEEFFQDFKPVVQ
GEFADGREKLYQLILTMQKGINAVYNSKKPSIALVQKHCIGGGLDLVSACDIRYASDDAVFSLRESKVAIVADMGSLQRL
PHLIGNAHTRELALTGKDVTANEAFQMGLVTKVTKDFDSLLVEGLKTANEIAENPTIVIRGVKQVLNHGVGKTIEEGLDY
VAVWNASMLDSKDFRSAIGGFMERKRPVFNPETRVDD
>Mature_277_residues
MNPSPFFTIERRKNVAILWLNRPEKRNAMNWPFWRDLPDMVAEIDADPKIHAFVIAGKGKSFSTGLDLEEFFQDFKPVVQ
GEFADGREKLYQLILTMQKGINAVYNSKKPSIALVQKHCIGGGLDLVSACDIRYASDDAVFSLRESKVAIVADMGSLQRL
PHLIGNAHTRELALTGKDVTANEAFQMGLVTKVTKDFDSLLVEGLKTANEIAENPTIVIRGVKQVLNHGVGKTIEEGLDY
VAVWNASMLDSKDFRSAIGGFMERKRPVFNPETRVDD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=255, Percent_Identity=39.2156862745098, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI194097323, Length=263, Percent_Identity=29.277566539924, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI4502327, Length=267, Percent_Identity=26.9662921348315, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI31542718, Length=257, Percent_Identity=25.2918287937743, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20127408, Length=203, Percent_Identity=26.6009852216749, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI68989263, Length=201, Percent_Identity=26.3681592039801, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI260274832, Length=255, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI45643119, Length=255, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI260275230, Length=255, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI157694516, Length=240, Percent_Identity=23.75, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI213417737, Length=240, Percent_Identity=23.75, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=27.6515151515151, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI221142681, Length=272, Percent_Identity=27.9411764705882, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787660, Length=266, Percent_Identity=25.9398496240602, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788597, Length=266, Percent_Identity=26.6917293233083, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788682, Length=208, Percent_Identity=27.8846153846154, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790281, Length=193, Percent_Identity=27.4611398963731, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082183, Length=259, Percent_Identity=22.7799227799228, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=273, Percent_Identity=34.0659340659341, Blast_Score=183, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17534483, Length=258, Percent_Identity=35.2713178294574, Blast_Score=167, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17554946, Length=260, Percent_Identity=29.2307692307692, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25145438, Length=255, Percent_Identity=29.4117647058824, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17560910, Length=240, Percent_Identity=27.0833333333333, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=246, Percent_Identity=28.8617886178862, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17558304, Length=223, Percent_Identity=26.457399103139, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17549921, Length=186, Percent_Identity=30.1075268817204, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508951, Length=207, Percent_Identity=27.536231884058, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=192, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=207, Percent_Identity=27.536231884058, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25141363, Length=230, Percent_Identity=29.1304347826087, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17535521, Length=258, Percent_Identity=23.6434108527132, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19920382, Length=272, Percent_Identity=33.0882352941176, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20129971, Length=261, Percent_Identity=28.735632183908, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24653477, Length=261, Percent_Identity=28.735632183908, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=27.9245283018868, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357171, Length=277, Percent_Identity=27.4368231046931, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24650670, Length=214, Percent_Identity=24.7663551401869, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24654903, Length=212, Percent_Identity=24.0566037735849, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 30884; Mature: 30884

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPSPFFTIERRKNVAILWLNRPEKRNAMNWPFWRDLPDMVAEIDADPKIHAFVIAGKGK
CCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEECCC
SFSTGLDLEEFFQDFKPVVQGEFADGREKLYQLILTMQKGINAVYNSKKPSIALVQKHCI
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
GGGLDLVSACDIRYASDDAVFSLRESKVAIVADMGSLQRLPHLIGNAHTRELALTGKDVT
CCCCHHHHHCCCEECCCCHHEEECCCCEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCC
ANEAFQMGLVTKVTKDFDSLLVEGLKTANEIAENPTIVIRGVKQVLNHGVGKTIEEGLDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCHHHHHCCCE
VAVWNASMLDSKDFRSAIGGFMERKRPVFNPETRVDD
EEEECCHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNPSPFFTIERRKNVAILWLNRPEKRNAMNWPFWRDLPDMVAEIDADPKIHAFVIAGKGK
CCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEECCC
SFSTGLDLEEFFQDFKPVVQGEFADGREKLYQLILTMQKGINAVYNSKKPSIALVQKHCI
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
GGGLDLVSACDIRYASDDAVFSLRESKVAIVADMGSLQRLPHLIGNAHTRELALTGKDVT
CCCCHHHHHCCCEECCCCHHEEECCCCEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCC
ANEAFQMGLVTKVTKDFDSLLVEGLKTANEIAENPTIVIRGVKQVLNHGVGKTIEEGLDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCHHHHHCCCE
VAVWNASMLDSKDFRSAIGGFMERKRPVFNPETRVDD
EEEECCHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA