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The map label for this gene is czcB [H]

Identifier: 183220705

GI number: 183220705

Start: 1371707

End: 1372888

Strand: Direct

Name: czcB [H]

Synonym: LEPBI_I1315

Alternate gene names: 183220705

Gene position: 1371707-1372888 (Clockwise)

Preceding gene: 183220704

Following gene: 183220706

Centisome position: 38.11

GC content: 38.24

Gene sequence:

>1182_bases
ATGCAAAATGAATTGAATTTAAAAAAAATTAGAAATATAAGTATCCTTGTATTACTTGGAAGTTTGTTGTATTTCGGATA
TACCAAGTTTTTTGGAGCTGGAAAAAAAACAGAAGCTCTTACCGAAGATAAATCAAAATTTATCATCTCGAATGAAATCC
AAAAAAACCATCCTTTCTCAGTCGTTTATCTGCAAGAAAAGGCATTGGAAGAGGAATTACAACTACCTGGCACTGTCTCG
TATGACATGAATAATGTGGCAAAAGTTGGATCTCGTGTGAATGGCCGAATTTTACAAGTATTTGTAAAAGAAGGGCAATA
TGTAAAAAAAGGAACTGCCATAGCTTCCATCCAATCCGTGGATTTAGGAACGACAGAAGCCAACTACTTAAAAGCCAGAG
CTAGGTTGGAGGCACTCAAAGTACAAGCAGATCGTGCAAAAGACTTATACGAGAGGAAAGTGACATCTGCAAAAGATTAC
GAAATGTCATTAATGGATTATAAGTCTGTCAAAGCAGAGATGGAAACATCACGAAATGCCTTGGAAAACTTAGGCCTCAA
TGAAGCTGAAATTGCAAACCTAGAAGCTGGAAAATACAATTCTAAAAACCTATTCATCAGAACTCCCATTTCAGGCACCG
TAACAGAAAGGGAAGCGATCATTGGACAAGCGGTGAATGCTCGTGATAATTTATTCACTGTCGCCGATTTGTCTGTTTTG
TGGATCAATTTAGAAGTGTATGAAAAAGATTTGGCATCGATCCGTATGGGAAATGAAGCAAAAGTAATTCCCATTGGTTC
CAAGGATGAATCTCTAAAAGCAGTTGTTTCCCATGTTGGTGATATCATTGATCCTGTGAAAAAAACAGCTGAAATCCGTT
TGGAAGTTCGTAATTCCAAAGGAAGGCTTCGCCCTGGTCAAAGTGTAACAGCAACAGTAGTCGGTGCGATGGTCGCATCA
TCGGTAAACAAAGCAAAGGTGATCCCTGCAGGATGTATTCATAAAATTGAAGGTGAAAACTATATCTTTGTTCGTAACGG
CGACGGTTCATTCTCAGCCAAAAAAATTGGTTTGGGAAAACTCTACGATAATTGGGTGGAAGTCACAGAAGGTGTGGCTT
CGGGAGAAGCCATTGTGGAAGAAGGAAGTTTTGTCTTAAAAAGTGAATATTTAAAACTATAA

Upstream 100 bases:

>100_bases
ATTAAGGAGTTATTATGAAATCATATACCTCTATTACAACGCTTTGGAAAGTTATAAGGCATCCATTGGGAAAATGGACA
ACTCGGAGTTATAGGCCAAT

Downstream 100 bases:

>100_bases
CAACTAGTTTTTTGTTGACATAACGCCCATTTCCTATTTATCTGTTTAGTATGAAAGACCTCACGGAAAAACAAGAATTT
GTTTTACAATACATCTCGGA

Product: putative cobalt-zinc-cadmium resistance protein CzcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MQNELNLKKIRNISILVLLGSLLYFGYTKFFGAGKKTEALTEDKSKFIISNEIQKNHPFSVVYLQEKALEEELQLPGTVS
YDMNNVAKVGSRVNGRILQVFVKEGQYVKKGTAIASIQSVDLGTTEANYLKARARLEALKVQADRAKDLYERKVTSAKDY
EMSLMDYKSVKAEMETSRNALENLGLNEAEIANLEAGKYNSKNLFIRTPISGTVTEREAIIGQAVNARDNLFTVADLSVL
WINLEVYEKDLASIRMGNEAKVIPIGSKDESLKAVVSHVGDIIDPVKKTAEIRLEVRNSKGRLRPGQSVTATVVGAMVAS
SVNKAKVIPAGCIHKIEGENYIFVRNGDGSFSAKKIGLGKLYDNWVEVTEGVASGEAIVEEGSFVLKSEYLKL

Sequences:

>Translated_393_residues
MQNELNLKKIRNISILVLLGSLLYFGYTKFFGAGKKTEALTEDKSKFIISNEIQKNHPFSVVYLQEKALEEELQLPGTVS
YDMNNVAKVGSRVNGRILQVFVKEGQYVKKGTAIASIQSVDLGTTEANYLKARARLEALKVQADRAKDLYERKVTSAKDY
EMSLMDYKSVKAEMETSRNALENLGLNEAEIANLEAGKYNSKNLFIRTPISGTVTEREAIIGQAVNARDNLFTVADLSVL
WINLEVYEKDLASIRMGNEAKVIPIGSKDESLKAVVSHVGDIIDPVKKTAEIRLEVRNSKGRLRPGQSVTATVVGAMVAS
SVNKAKVIPAGCIHKIEGENYIFVRNGDGSFSAKKIGLGKLYDNWVEVTEGVASGEAIVEEGSFVLKSEYLKL
>Mature_393_residues
MQNELNLKKIRNISILVLLGSLLYFGYTKFFGAGKKTEALTEDKSKFIISNEIQKNHPFSVVYLQEKALEEELQLPGTVS
YDMNNVAKVGSRVNGRILQVFVKEGQYVKKGTAIASIQSVDLGTTEANYLKARARLEALKVQADRAKDLYERKVTSAKDY
EMSLMDYKSVKAEMETSRNALENLGLNEAEIANLEAGKYNSKNLFIRTPISGTVTEREAIIGQAVNARDNLFTVADLSVL
WINLEVYEKDLASIRMGNEAKVIPIGSKDESLKAVVSHVGDIIDPVKKTAEIRLEVRNSKGRLRPGQSVTATVVGAMVAS
SVNKAKVIPAGCIHKIEGENYIFVRNGDGSFSAKKIGLGKLYDNWVEVTEGVASGEAIVEEGSFVLKSEYLKL

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=310, Percent_Identity=24.8387096774194, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43295; Mature: 43295

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNELNLKKIRNISILVLLGSLLYFGYTKFFGAGKKTEALTEDKSKFIISNEIQKNHPFS
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCCCCCEE
VVYLQEKALEEELQLPGTVSYDMNNVAKVGSRVNGRILQVFVKEGQYVKKGTAIASIQSV
EEEEEHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCEEEEEECCCCEEECCCEEEEEEEC
DLGTTEANYLKARARLEALKVQADRAKDLYERKVTSAKDYEMSLMDYKSVKAEMETSRNA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHH
LENLGLNEAEIANLEAGKYNSKNLFIRTPISGTVTEREAIIGQAVNARDNLFTVADLSVL
HHHCCCCHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEE
WINLEVYEKDLASIRMGNEAKVIPIGSKDESLKAVVSHVGDIIDPVKKTAEIRLEVRNSK
EEEEHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEECCC
GRLRPGQSVTATVVGAMVASSVNKAKVIPAGCIHKIEGENYIFVRNGDGSFSAKKIGLGK
CCCCCCCCHHHHHHHHHHHHCCCCCEECCHHHHEEECCCCEEEEECCCCCCCCCCCCCHH
LYDNWVEVTEGVASGEAIVEEGSFVLKSEYLKL
HHHHHHHHHCCCCCCCHHHHCCCEEEEHHHHCC
>Mature Secondary Structure
MQNELNLKKIRNISILVLLGSLLYFGYTKFFGAGKKTEALTEDKSKFIISNEIQKNHPFS
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCCCCCEE
VVYLQEKALEEELQLPGTVSYDMNNVAKVGSRVNGRILQVFVKEGQYVKKGTAIASIQSV
EEEEEHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCEEEEEECCCCEEECCCEEEEEEEC
DLGTTEANYLKARARLEALKVQADRAKDLYERKVTSAKDYEMSLMDYKSVKAEMETSRNA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHH
LENLGLNEAEIANLEAGKYNSKNLFIRTPISGTVTEREAIIGQAVNARDNLFTVADLSVL
HHHCCCCHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEE
WINLEVYEKDLASIRMGNEAKVIPIGSKDESLKAVVSHVGDIIDPVKKTAEIRLEVRNSK
EEEEHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEECCC
GRLRPGQSVTATVVGAMVASSVNKAKVIPAGCIHKIEGENYIFVRNGDGSFSAKKIGLGK
CCCCCCCCHHHHHHHHHHHHCCCCCEECCHHHHEEECCCCEEEEECCCCCCCCCCCCCHH
LYDNWVEVTEGVASGEAIVEEGSFVLKSEYLKL
HHHHHHHHHCCCCCCCHHHHCCCEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]