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The map label for this gene is cmpR [H]

Identifier: 183220622

GI number: 183220622

Start: 1278737

End: 1279639

Strand: Reverse

Name: cmpR [H]

Synonym: LEPBI_I1228

Alternate gene names: 183220622

Gene position: 1279639-1278737 (Counterclockwise)

Preceding gene: 183220625

Following gene: 183220619

Centisome position: 35.55

GC content: 36.54

Gene sequence:

>903_bases
ATGGAATTCAGACAGATCGTTTATTTTCTTGAAATCGCTAACACAGGCACATTCCAAAAAGCGGCAACGCAACTAGGATT
AACACAACCGGCACTCTCTAGACAAATTTTTCTTTTAGAAAAGGAATTAGGAGTCATAGTATTGGAAAGAGGAGGAAGGT
CTGTTCGACTAACACACGAAGGTGAAAAGTTCTATCAGTATTCAATTCGAATGAAAGAATTATGGGAAGAGATACAAAAT
GGTTTTGCAAAAGAAAACGAACTCAAAGGAAACTTTTCCATTTCAGCGGGAGGTACCGTTTCTGCATGGATCTTACCTCA
AATCTTAAAGGAAATCCTAACAAAAAGAAAAGGACTATCGCTTTCAGTCCGTGAAGGAGATGCTAGTGAAACAAAAAACT
CAGTGTTAAAAGGAGAAGTAGATCTTGGGATTTTGACAGGTCCCATTGCAGAACCTAGTCTGAATGTAATCGAATTTTTA
TCCGATCAGATTTATCCTGTCGCAACAAAGGACCATCCAATTTTTTTAAAAAAGAAAATTAGAATCGAGGACTTAAAAAA
ACAATCCGTTGTCTTTTTTCATCCGGGTTCTGCTCTTAGAAAGGCAGTGGAGAAGAAGATTAAATCGTTCTCTAAAGAAT
TTGGCCCCAATATCACAATGGAACTGAGGAGTGTAGAATCCGTTATCAAATCTTTGGAAGCCGGATTAGGAATCGGTTTT
TTATCCAAATATTCGATGAATCAAAAACTACAAAAAATTAATTTCGAAGACTGGAATGTGGAAAGAAAATTTTATCTTTG
TTATCGTAAAAAATCTGGACCCGGACTTACGATGCTTGCAGAAGAAATTTTAAGATCCACTGAACTTTGGAAATCCAAAA
AAGAAAACTCCTCCCTTTCCTAG

Upstream 100 bases:

>100_bases
TTGTCCCATATTTTCCTCTTGGTAATAAGAGTATCAAAATAATTGATATAATGCAAATAAATTGGTTTTATAATATATAT
AACTAATTGTTATATGTAGT

Downstream 100 bases:

>100_bases
GAATGGTTGGACCATCATTTTTAATCCTGTTCAAAAATGAAAACGATAGTTTGCACCGACTTGAACGTAAGACAATATTG
TCTTTGAATCATATAACATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MEFRQIVYFLEIANTGTFQKAATQLGLTQPALSRQIFLLEKELGVIVLERGGRSVRLTHEGEKFYQYSIRMKELWEEIQN
GFAKENELKGNFSISAGGTVSAWILPQILKEILTKRKGLSLSVREGDASETKNSVLKGEVDLGILTGPIAEPSLNVIEFL
SDQIYPVATKDHPIFLKKKIRIEDLKKQSVVFFHPGSALRKAVEKKIKSFSKEFGPNITMELRSVESVIKSLEAGLGIGF
LSKYSMNQKLQKINFEDWNVERKFYLCYRKKSGPGLTMLAEEILRSTELWKSKKENSSLS

Sequences:

>Translated_300_residues
MEFRQIVYFLEIANTGTFQKAATQLGLTQPALSRQIFLLEKELGVIVLERGGRSVRLTHEGEKFYQYSIRMKELWEEIQN
GFAKENELKGNFSISAGGTVSAWILPQILKEILTKRKGLSLSVREGDASETKNSVLKGEVDLGILTGPIAEPSLNVIEFL
SDQIYPVATKDHPIFLKKKIRIEDLKKQSVVFFHPGSALRKAVEKKIKSFSKEFGPNITMELRSVESVIKSLEAGLGIGF
LSKYSMNQKLQKINFEDWNVERKFYLCYRKKSGPGLTMLAEEILRSTELWKSKKENSSLS
>Mature_300_residues
MEFRQIVYFLEIANTGTFQKAATQLGLTQPALSRQIFLLEKELGVIVLERGGRSVRLTHEGEKFYQYSIRMKELWEEIQN
GFAKENELKGNFSISAGGTVSAWILPQILKEILTKRKGLSLSVREGDASETKNSVLKGEVDLGILTGPIAEPSLNVIEFL
SDQIYPVATKDHPIFLKKKIRIEDLKKQSVVFFHPGSALRKAVEKKIKSFSKEFGPNITMELRSVESVIKSLEAGLGIGF
LSKYSMNQKLQKINFEDWNVERKFYLCYRKKSGPGLTMLAEEILRSTELWKSKKENSSLS

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=280, Percent_Identity=26.7857142857143, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788481, Length=251, Percent_Identity=25.8964143426295, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787879, Length=250, Percent_Identity=27.2, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788887, Length=257, Percent_Identity=25.2918287937743, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082132, Length=259, Percent_Identity=21.6216216216216, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787530, Length=321, Percent_Identity=23.6760124610592, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=23.5772357723577, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787601, Length=197, Percent_Identity=26.9035532994924, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788297, Length=261, Percent_Identity=23.7547892720307, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788748, Length=245, Percent_Identity=22.0408163265306, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790208, Length=282, Percent_Identity=21.9858156028369, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787806, Length=277, Percent_Identity=20.5776173285199, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081904, Length=214, Percent_Identity=25.2336448598131, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786401, Length=254, Percent_Identity=24.8031496062992, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790399, Length=251, Percent_Identity=26.2948207171315, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34015; Mature: 34015

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFRQIVYFLEIANTGTFQKAATQLGLTQPALSRQIFLLEKELGVIVLERGGRSVRLTHE
CCHHHEEEEEEECCCCCHHHHHHHHCCCCHHHHHEEEEEECCCCEEEEECCCCEEEEEEC
GEKFYQYSIRMKELWEEIQNGFAKENELKGNFSISAGGTVSAWILPQILKEILTKRKGLS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCE
LSVREGDASETKNSVLKGEVDLGILTGPIAEPSLNVIEFLSDQIYPVATKDHPIFLKKKI
EEEECCCCHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHCCCEEEECCCCCEEEEECC
RIEDLKKQSVVFFHPGSALRKAVEKKIKSFSKEFGPNITMELRSVESVIKSLEAGLGIGF
CHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCHHH
LSKYSMNQKLQKINFEDWNVERKFYLCYRKKSGPGLTMLAEEILRSTELWKSKKENSSLS
HHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEFRQIVYFLEIANTGTFQKAATQLGLTQPALSRQIFLLEKELGVIVLERGGRSVRLTHE
CCHHHEEEEEEECCCCCHHHHHHHHCCCCHHHHHEEEEEECCCCEEEEECCCCEEEEEEC
GEKFYQYSIRMKELWEEIQNGFAKENELKGNFSISAGGTVSAWILPQILKEILTKRKGLS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCE
LSVREGDASETKNSVLKGEVDLGILTGPIAEPSLNVIEFLSDQIYPVATKDHPIFLKKKI
EEEECCCCHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHCCCEEEECCCCCEEEEECC
RIEDLKKQSVVFFHPGSALRKAVEKKIKSFSKEFGPNITMELRSVESVIKSLEAGLGIGF
CHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCHHH
LSKYSMNQKLQKINFEDWNVERKFYLCYRKKSGPGLTMLAEEILRSTELWKSKKENSSLS
HHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]