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The map label for this gene is cysW [H]

Identifier: 183220582

GI number: 183220582

Start: 1234336

End: 1235139

Strand: Reverse

Name: cysW [H]

Synonym: LEPBI_I1186

Alternate gene names: 183220582

Gene position: 1235139-1234336 (Counterclockwise)

Preceding gene: 183220583

Following gene: 183220581

Centisome position: 34.31

GC content: 40.55

Gene sequence:

>804_bases
ATGAAATTGAAACTTGTTCCCTTCTTACTGATAATTATCGCATACACGTTGTTTGCTGTATTGTTAATTTTGCCGATTTA
TACAGTCTTTTCTGAGGCTTTTTCCGAAGGATTGGATAAGTATTGGTCCTCCATCACAAGTGAATATGCACTTTTTGCCA
TTGGACTTACAGTCAAGGTTTCGGTTGTATCCGTGATCTTAAATACCTTATTTGGAATCACTGCGGCCTTCACCATCACT
CGGTTTTCGTTTCCAGGGAAAAATTTACTCGTGACGATTATCGATTCTCCTTTCGCGGTATCTCCTGTGGTATCTGGACT
CATCTTTTTGTTGTTATTCGGAAGGCAAGGTACCTTTGGTGACTTCCTATCAGAGCATCATATTAAAATTGTATTCAATA
CTCCAGGACTCATCATTGCAACCGTGTTCATCACGTTTCCATTTGTGGCACGGGAACTCATCCCACTCATGCAAAGCCAG
GGTCGTGAAGAAGAAGAAGCAGGATTGTTACTCGGAGCAAGTTTTGGACAATTATTATGGCGAATCATTTTGCCAAATCT
CAAATGGGGTCTGTTATATGGGATCATCCTTTGTAATGCAAGAGCTATGGGGGAATTTGGAGCCGTTTCTGTCTTAAGTG
GTCACATCCGTGGTAAAACCACAACCCTTCCCCTATACATCGAAATGTTATACAATGAATTTGATTCCGTTGGTGCGTTT
GCTTGTGCCACCTTACTAGTGTTTTTATCACTTCTAACCCTCATCTTTAAATTGATTTTGGAAAAACGAACCGAGAGACC
ATAA

Upstream 100 bases:

>100_bases
ATGAGAAGGCAACATCCATTGCGATTGTGATGTTACTCTCTTCGTTTTTCTTTATGTTTCTTATTAATTTATTACAAGAA
CGGGCTTCGAAAAAACTCAC

Downstream 100 bases:

>100_bases
CATGCCTATTGAAATACAAAATGTACATAAAACTTTTGGATCGTTTACAGCCTTAAAAGATGTGAACCTTACCATCCCTG
ATGGAGAACTTGTGGCCTTA

Product: sulfate ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKLKLVPFLLIIIAYTLFAVLLILPIYTVFSEAFSEGLDKYWSSITSEYALFAIGLTVKVSVVSVILNTLFGITAAFTIT
RFSFPGKNLLVTIIDSPFAVSPVVSGLIFLLLFGRQGTFGDFLSEHHIKIVFNTPGLIIATVFITFPFVARELIPLMQSQ
GREEEEAGLLLGASFGQLLWRIILPNLKWGLLYGIILCNARAMGEFGAVSVLSGHIRGKTTTLPLYIEMLYNEFDSVGAF
ACATLLVFLSLLTLIFKLILEKRTERP

Sequences:

>Translated_267_residues
MKLKLVPFLLIIIAYTLFAVLLILPIYTVFSEAFSEGLDKYWSSITSEYALFAIGLTVKVSVVSVILNTLFGITAAFTIT
RFSFPGKNLLVTIIDSPFAVSPVVSGLIFLLLFGRQGTFGDFLSEHHIKIVFNTPGLIIATVFITFPFVARELIPLMQSQ
GREEEEAGLLLGASFGQLLWRIILPNLKWGLLYGIILCNARAMGEFGAVSVLSGHIRGKTTTLPLYIEMLYNEFDSVGAF
ACATLLVFLSLLTLIFKLILEKRTERP
>Mature_267_residues
MKLKLVPFLLIIIAYTLFAVLLILPIYTVFSEAFSEGLDKYWSSITSEYALFAIGLTVKVSVVSVILNTLFGITAAFTIT
RFSFPGKNLLVTIIDSPFAVSPVVSGLIFLLLFGRQGTFGDFLSEHHIKIVFNTPGLIIATVFITFPFVARELIPLMQSQ
GREEEEAGLLLGASFGQLLWRIILPNLKWGLLYGIILCNARAMGEFGAVSVLSGHIRGKTTTLPLYIEMLYNEFDSVGAF
ACATLLVFLSLLTLIFKLILEKRTERP

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=259, Percent_Identity=48.2625482625483, Blast_Score=261, Evalue=2e-71,
Organism=Escherichia coli, GI1788764, Length=207, Percent_Identity=36.231884057971, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786980, Length=215, Percent_Identity=30.2325581395349, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29555; Mature: 29555

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKLVPFLLIIIAYTLFAVLLILPIYTVFSEAFSEGLDKYWSSITSEYALFAIGLTVKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVVSVILNTLFGITAAFTITRFSFPGKNLLVTIIDSPFAVSPVVSGLIFLLLFGRQGTFG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHH
DFLSEHHIKIVFNTPGLIIATVFITFPFVARELIPLMQSQGREEEEAGLLLGASFGQLLW
HHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECHHHHHHH
RIILPNLKWGLLYGIILCNARAMGEFGAVSVLSGHIRGKTTTLPLYIEMLYNEFDSVGAF
HHHHCCCHHHHHHHHHHHCCHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ACATLLVFLSLLTLIFKLILEKRTERP
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLKLVPFLLIIIAYTLFAVLLILPIYTVFSEAFSEGLDKYWSSITSEYALFAIGLTVKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVVSVILNTLFGITAAFTITRFSFPGKNLLVTIIDSPFAVSPVVSGLIFLLLFGRQGTFG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHH
DFLSEHHIKIVFNTPGLIIATVFITFPFVARELIPLMQSQGREEEEAGLLLGASFGQLLW
HHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECHHHHHHH
RIILPNLKWGLLYGIILCNARAMGEFGAVSVLSGHIRGKTTTLPLYIEMLYNEFDSVGAF
HHHHCCCHHHHHHHHHHHCCHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ACATLLVFLSLLTLIFKLILEKRTERP
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]