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The map label for this gene is trpS [H]

Identifier: 183220527

GI number: 183220527

Start: 1176545

End: 1177513

Strand: Reverse

Name: trpS [H]

Synonym: LEPBI_I1129

Alternate gene names: 183220527

Gene position: 1177513-1176545 (Counterclockwise)

Preceding gene: 183220528

Following gene: 183220526

Centisome position: 32.71

GC content: 38.49

Gene sequence:

>969_bases
TTGAGAGTCCTTACTGGTTTACAACCTTCTGGGAAATTACATTTAGGAAATTATTTTTCAGCGATCAAAAAGATTTTGGA
TTACCAATCCAAAGAAGAACTTTTTCTTTTTATCGCAAACCTACACGCACTCACAACATTCCGTTCCAAAGAAGAATTAA
AAGAATACACGATTGGATGTGCCATCGACTTACTCGCGCTTGGTGTCGATCCAAATAAAACTGTGTTTTGGGTGCAAAGC
GATGTGCCAGAGGTGACAGAACTCACTTGGTATTTATCCCAATCCATTACCGTATCCCAATTACAATTAGCTCATTCTTT
TAAAGACAAAGTTGCCAAAGGATTTGTGCCAGGAGCAGGACTCTTTACCTATCCCATTCTTATGGCAAGTGACATCTTAC
TTTTTTCAGCAGAAAAAGTTCCCGTAGGCAAAGACCAAAAACAACATTTGGAATTTGCGCGAGATATTGCAGAACGATTT
AATACCCAATTCGGATCTGTTCTTACTATCCCTGAGCCAGACATCGATGAAAACACAGCTACGGTTCCGGGTGTGGATGG
AGCCAAAATGTCAAAATCCTATCAGAACACGATCGACTTCTTTGGCACGGAAAAAGAGATCAAAAAGAAAGTGATGTCGA
TTGTGAGTGATTCAAAAGCCATCGAAGAACCAAAAAATCCAGAGGAATCTGTGATCTTTCAAATCCATTCTTTATTTTTA
TCCGACACAGAAAAAGAATCCCAAAAACAAAAATACACAAACGGTGGGTTTGGGTATGGAGATTTAAAAAAAGATCTACT
CGAATCCATTCTCTCTCATTTTGCCCCATTCCGATCCAAACGAGAAGAATTATCACAAAACTTAGATTATGTGCATTCTG
TCTTAAAATCGGGAAAAGAGAAAGCAAAGGAAGTGGCAGAAAAAAAATTGGATGCCATCCGAAACACATTAGGAATCTAC
CCTTTTTAA

Upstream 100 bases:

>100_bases
TTCACAAAGATAGTGGGAATCCAAATCCAGATCCAAACCTTGAGTCGACTGAATCCGAAAGTGCAGAGGCAAGTGATATG
GCAAATGCGGAGGAAGGTAT

Downstream 100 bases:

>100_bases
ATTCCAAAGAGACCAAGTGATCGATTTTGAACCTCTCTTCCTATGAGGGTCAAAACAAAACTTCTTCCGAATTCAAGTTT
TGGTTGGTTTTGTTTCGGGA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRVLTGLQPSGKLHLGNYFSAIKKILDYQSKEELFLFIANLHALTTFRSKEELKEYTIGCAIDLLALGVDPNKTVFWVQS
DVPEVTELTWYLSQSITVSQLQLAHSFKDKVAKGFVPGAGLFTYPILMASDILLFSAEKVPVGKDQKQHLEFARDIAERF
NTQFGSVLTIPEPDIDENTATVPGVDGAKMSKSYQNTIDFFGTEKEIKKKVMSIVSDSKAIEEPKNPEESVIFQIHSLFL
SDTEKESQKQKYTNGGFGYGDLKKDLLESILSHFAPFRSKREELSQNLDYVHSVLKSGKEKAKEVAEKKLDAIRNTLGIY
PF

Sequences:

>Translated_322_residues
MRVLTGLQPSGKLHLGNYFSAIKKILDYQSKEELFLFIANLHALTTFRSKEELKEYTIGCAIDLLALGVDPNKTVFWVQS
DVPEVTELTWYLSQSITVSQLQLAHSFKDKVAKGFVPGAGLFTYPILMASDILLFSAEKVPVGKDQKQHLEFARDIAERF
NTQFGSVLTIPEPDIDENTATVPGVDGAKMSKSYQNTIDFFGTEKEIKKKVMSIVSDSKAIEEPKNPEESVIFQIHSLFL
SDTEKESQKQKYTNGGFGYGDLKKDLLESILSHFAPFRSKREELSQNLDYVHSVLKSGKEKAKEVAEKKLDAIRNTLGIY
PF
>Mature_322_residues
MRVLTGLQPSGKLHLGNYFSAIKKILDYQSKEELFLFIANLHALTTFRSKEELKEYTIGCAIDLLALGVDPNKTVFWVQS
DVPEVTELTWYLSQSITVSQLQLAHSFKDKVAKGFVPGAGLFTYPILMASDILLFSAEKVPVGKDQKQHLEFARDIAERF
NTQFGSVLTIPEPDIDENTATVPGVDGAKMSKSYQNTIDFFGTEKEIKKKVMSIVSDSKAIEEPKNPEESVIFQIHSLFL
SDTEKESQKQKYTNGGFGYGDLKKDLLESILSHFAPFRSKREELSQNLDYVHSVLKSGKEKAKEVAEKKLDAIRNTLGIY
PF

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=326, Percent_Identity=32.5153374233129, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI41352700, Length=173, Percent_Identity=40.4624277456647, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1789786, Length=330, Percent_Identity=34.2424242424242, Blast_Score=176, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71982800, Length=328, Percent_Identity=33.5365853658537, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71982793, Length=329, Percent_Identity=33.434650455927, Blast_Score=158, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6320474, Length=349, Percent_Identity=31.5186246418338, Blast_Score=132, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24666151, Length=331, Percent_Identity=30.2114803625378, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36202; Mature: 36202

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLTGLQPSGKLHLGNYFSAIKKILDYQSKEELFLFIANLHALTTFRSKEELKEYTIGC
CCCCCCCCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIDLLALGVDPNKTVFWVQSDVPEVTELTWYLSQSITVSQLQLAHSFKDKVAKGFVPGAG
HHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
LFTYPILMASDILLFSAEKVPVGKDQKQHLEFARDIAERFNTQFGSVLTIPEPDIDENTA
HHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCC
TVPGVDGAKMSKSYQNTIDFFGTEKEIKKKVMSIVSDSKAIEEPKNPEESVIFQIHSLFL
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SDTEKESQKQKYTNGGFGYGDLKKDLLESILSHFAPFRSKREELSQNLDYVHSVLKSGKE
HCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAKEVAEKKLDAIRNTLGIYPF
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRVLTGLQPSGKLHLGNYFSAIKKILDYQSKEELFLFIANLHALTTFRSKEELKEYTIGC
CCCCCCCCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIDLLALGVDPNKTVFWVQSDVPEVTELTWYLSQSITVSQLQLAHSFKDKVAKGFVPGAG
HHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
LFTYPILMASDILLFSAEKVPVGKDQKQHLEFARDIAERFNTQFGSVLTIPEPDIDENTA
HHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCC
TVPGVDGAKMSKSYQNTIDFFGTEKEIKKKVMSIVSDSKAIEEPKNPEESVIFQIHSLFL
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SDTEKESQKQKYTNGGFGYGDLKKDLLESILSHFAPFRSKREELSQNLDYVHSVLKSGKE
HCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAKEVAEKKLDAIRNTLGIYPF
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]