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The map label for this gene is mcpA [H]

Identifier: 183220484

GI number: 183220484

Start: 1130476

End: 1132380

Strand: Reverse

Name: mcpA [H]

Synonym: LEPBI_I1083

Alternate gene names: 183220484

Gene position: 1132380-1130476 (Counterclockwise)

Preceding gene: 183220485

Following gene: 183220483

Centisome position: 31.46

GC content: 37.27

Gene sequence:

>1905_bases
ATGAAAGAAAATATGCGTTCTATATTTAGAACAGTTTTTATCACGATAACGATCGCAATGTTATCACTTGTCATCTTTAC
AATGCAATTAAGAAAAGCTTCGGAAGTTGTAGCAGAGGCTACGATTTCTCGATATGAATCTTATTTGTTAGCAGATGAAT
TACGCCAAAGTTCTGATGACTTGACTAGACTTGCTAGAACTTTCGTAATCTCAGGTGGCGATCCTAAATGGGAAAAACAA
TACTTCGATATTCTTGATATTCGAAACGGAGTCAAACCTAGACCCACACAATACGAAAATATTTATTGGGATTTTGTTGC
GGCAGGAGAACCAGCACCTCGTCCAAGTTCCAAAACAATCGCACTTTTAGATTTAATGAAAGAGAAGGGATTTTCAGAAA
AAGAATTGGCAAAACTTGATGAAGCAAAATTAAAATCAGATGCCCTAGTGAATACAGAAACCATTGCAATGAATATGGTA
AAAGGTTTGTATGTCGATTCAAATGGTAAATTTACTATCAAAAACAAACCAAATTTAGAAGAAGCTCGTCGTTTAATGCA
TAATGACGAATATCACAAAAACAAAGCAAAAATCATGAAACCAGTATCTGAATTTTTTGATCTTTTGGACAAACGTACTC
AATCCAAGGTTGATGACGCAATATCCAGCCAAAACTTTTGGAATTGGATCGTGATCATATTTGTATTCATCACATTATGT
ATTTTAACGTATGCGGGATATGAATTACGATTATTGTTTAAGTATTTGGGTGGTGAACCTGCATATGCCAATACAATTGT
GACTGAAGTCGCTTCAGGAAATTTAAATTTAACGATTCAAACTTTACCAAAAGATAACATCAGTATGTTGTATTCGATAA
AAGGGATGGTGGAAAGATTAAAACTAATGATAAGCGAAACCCAACAAGTGGTTGATGCTGCCGGAAAAGGGAATTTAAAA
ACGAGAGTTTCATTAAATAATAAACAAGGATTTGCTAAAGATTTAGGAGAAAGTGTAAACCTCTTGGCGAAAACTAGCTC
CAATATTATTGATGATGTGAACCATGTACTTGTAGCAATGGCAGATGGAGACTTAACACAAAGGGTATCACAAAATTACC
AAGGTGATTTTGAAACTTTGGCAAACTCTTTAAATAATGCATTAGAAAAATTATCACAAGCATTATCTGAAGTTCGAAGT
TCGGCAGTCGTCATTTCGCAGGCATCCAGCCAAATCTCTTCCACCTCACTATCCTTGGCAGAGGCAACATCCGAACAAGC
CTCAAGCATCGAACAAACAACAGCCGCTGTTGAAGAGATGTCCGCATCCATCACACAAACCAACCAAAATACAAAGGTAA
CCGATGATATTGCAAAAAAATCTGCAAATGATGCAATCAAGGGTGGAGAATCTGTGAATGCAACTGTATTAGCAATGTCA
AAAATTGCCGAAAAAATTGGAATCATCAATGAAATCTCTGGGCAAACAAACCTACTTGCATTAAACGCGGCGATTGAAGC
CGCAAGAGCTGGCGAACAAGGAATGGGATTTGCTGTTGTTGCTTCTGAAGTCGGAAAGTTAGCAGAAAGAAGCCAAGCCG
CTGCCAAAGAAATTAGCCACCTAGCAAATGCAAGTTTAGTGACGGCGGAAGAAGCCGGTCAACTGCTGAATCAAATTGTA
CCTTCGATAAGCAAAACGGCAGAATTAGTCCAAGACATTTCTTTTTCTTCCAAAGAACAAGCTGTAGGTGTTCAGCAAAT
TACAGATGCAATGACATTAGTGAATGAAAGTACACAAAACAATGCGGCAAGCTCAGAAGAATTGTCCGCCACTGCAAATG
AAATGAGCCGGCAAGCAGAACATCTCATGGTTTTAGTGGAACAATTTAGATTCAAATTAGAATAA

Upstream 100 bases:

>100_bases
TTTGTAAAGAATACCTTTGTGGTTCAAATTGGATATTCTATGAAATTCTAAGTCAATTCTTGCAAACATTAATCATATAA
ACATAAGAAAGGAAATAAAA

Downstream 100 bases:

>100_bases
AGGAAACTAAAAAATGTGGGATACGCCATAGAATCGATCTCTCTCAATTCAAAATCCATCGATTCCATTCTAATGGAATT
TGAATTGGGAGATGGAACCC

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MKENMRSIFRTVFITITIAMLSLVIFTMQLRKASEVVAEATISRYESYLLADELRQSSDDLTRLARTFVISGGDPKWEKQ
YFDILDIRNGVKPRPTQYENIYWDFVAAGEPAPRPSSKTIALLDLMKEKGFSEKELAKLDEAKLKSDALVNTETIAMNMV
KGLYVDSNGKFTIKNKPNLEEARRLMHNDEYHKNKAKIMKPVSEFFDLLDKRTQSKVDDAISSQNFWNWIVIIFVFITLC
ILTYAGYELRLLFKYLGGEPAYANTIVTEVASGNLNLTIQTLPKDNISMLYSIKGMVERLKLMISETQQVVDAAGKGNLK
TRVSLNNKQGFAKDLGESVNLLAKTSSNIIDDVNHVLVAMADGDLTQRVSQNYQGDFETLANSLNNALEKLSQALSEVRS
SAVVISQASSQISSTSLSLAEATSEQASSIEQTTAAVEEMSASITQTNQNTKVTDDIAKKSANDAIKGGESVNATVLAMS
KIAEKIGIINEISGQTNLLALNAAIEAARAGEQGMGFAVVASEVGKLAERSQAAAKEISHLANASLVTAEEAGQLLNQIV
PSISKTAELVQDISFSSKEQAVGVQQITDAMTLVNESTQNNAASSEELSATANEMSRQAEHLMVLVEQFRFKLE

Sequences:

>Translated_634_residues
MKENMRSIFRTVFITITIAMLSLVIFTMQLRKASEVVAEATISRYESYLLADELRQSSDDLTRLARTFVISGGDPKWEKQ
YFDILDIRNGVKPRPTQYENIYWDFVAAGEPAPRPSSKTIALLDLMKEKGFSEKELAKLDEAKLKSDALVNTETIAMNMV
KGLYVDSNGKFTIKNKPNLEEARRLMHNDEYHKNKAKIMKPVSEFFDLLDKRTQSKVDDAISSQNFWNWIVIIFVFITLC
ILTYAGYELRLLFKYLGGEPAYANTIVTEVASGNLNLTIQTLPKDNISMLYSIKGMVERLKLMISETQQVVDAAGKGNLK
TRVSLNNKQGFAKDLGESVNLLAKTSSNIIDDVNHVLVAMADGDLTQRVSQNYQGDFETLANSLNNALEKLSQALSEVRS
SAVVISQASSQISSTSLSLAEATSEQASSIEQTTAAVEEMSASITQTNQNTKVTDDIAKKSANDAIKGGESVNATVLAMS
KIAEKIGIINEISGQTNLLALNAAIEAARAGEQGMGFAVVASEVGKLAERSQAAAKEISHLANASLVTAEEAGQLLNQIV
PSISKTAELVQDISFSSKEQAVGVQQITDAMTLVNESTQNNAASSEELSATANEMSRQAEHLMVLVEQFRFKLE
>Mature_634_residues
MKENMRSIFRTVFITITIAMLSLVIFTMQLRKASEVVAEATISRYESYLLADELRQSSDDLTRLARTFVISGGDPKWEKQ
YFDILDIRNGVKPRPTQYENIYWDFVAAGEPAPRPSSKTIALLDLMKEKGFSEKELAKLDEAKLKSDALVNTETIAMNMV
KGLYVDSNGKFTIKNKPNLEEARRLMHNDEYHKNKAKIMKPVSEFFDLLDKRTQSKVDDAISSQNFWNWIVIIFVFITLC
ILTYAGYELRLLFKYLGGEPAYANTIVTEVASGNLNLTIQTLPKDNISMLYSIKGMVERLKLMISETQQVVDAAGKGNLK
TRVSLNNKQGFAKDLGESVNLLAKTSSNIIDDVNHVLVAMADGDLTQRVSQNYQGDFETLANSLNNALEKLSQALSEVRS
SAVVISQASSQISSTSLSLAEATSEQASSIEQTTAAVEEMSASITQTNQNTKVTDDIAKKSANDAIKGGESVNATVLAMS
KIAEKIGIINEISGQTNLLALNAAIEAARAGEQGMGFAVVASEVGKLAERSQAAAKEISHLANASLVTAEEAGQLLNQIV
PSISKTAELVQDISFSSKEQAVGVQQITDAMTLVNESTQNNAASSEELSATANEMSRQAEHLMVLVEQFRFKLE

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=286, Percent_Identity=37.7622377622378, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI2367378, Length=285, Percent_Identity=34.7368421052632, Blast_Score=149, Evalue=7e-37,
Organism=Escherichia coli, GI1788195, Length=258, Percent_Identity=35.2713178294574, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1788194, Length=285, Percent_Identity=34.3859649122807, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789453, Length=228, Percent_Identity=39.0350877192982, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 69514; Mature: 69514

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENMRSIFRTVFITITIAMLSLVIFTMQLRKASEVVAEATISRYESYLLADELRQSSDD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LTRLARTFVISGGDPKWEKQYFDILDIRNGVKPRPTQYENIYWDFVAAGEPAPRPSSKTI
HHHHHHHHEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHH
ALLDLMKEKGFSEKELAKLDEAKLKSDALVNTETIAMNMVKGLYVDSNGKFTIKNKPNLE
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCEEEECCCCCHH
EARRLMHNDEYHKNKAKIMKPVSEFFDLLDKRTQSKVDDAISSQNFWNWIVIIFVFITLC
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ILTYAGYELRLLFKYLGGEPAYANTIVTEVASGNLNLTIQTLPKDNISMLYSIKGMVERL
HHHHCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
KLMISETQQVVDAAGKGNLKTRVSLNNKQGFAKDLGESVNLLAKTSSNIIDDVNHVLVAM
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
ADGDLTQRVSQNYQGDFETLANSLNNALEKLSQALSEVRSSAVVISQASSQISSTSLSLA
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHH
EATSEQASSIEQTTAAVEEMSASITQTNQNTKVTDDIAKKSANDAIKGGESVNATVLAMS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHCCCCCCCHHHHHHH
KIAEKIGIINEISGQTNLLALNAAIEAARAGEQGMGFAVVASEVGKLAERSQAAAKEISH
HHHHHHCCHHHCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LANASLVTAEEAGQLLNQIVPSISKTAELVQDISFSSKEQAVGVQQITDAMTLVNESTQN
HHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
NAASSEELSATANEMSRQAEHLMVLVEQFRFKLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKENMRSIFRTVFITITIAMLSLVIFTMQLRKASEVVAEATISRYESYLLADELRQSSDD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LTRLARTFVISGGDPKWEKQYFDILDIRNGVKPRPTQYENIYWDFVAAGEPAPRPSSKTI
HHHHHHHHEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHH
ALLDLMKEKGFSEKELAKLDEAKLKSDALVNTETIAMNMVKGLYVDSNGKFTIKNKPNLE
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCEEEECCCCCHH
EARRLMHNDEYHKNKAKIMKPVSEFFDLLDKRTQSKVDDAISSQNFWNWIVIIFVFITLC
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ILTYAGYELRLLFKYLGGEPAYANTIVTEVASGNLNLTIQTLPKDNISMLYSIKGMVERL
HHHHCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
KLMISETQQVVDAAGKGNLKTRVSLNNKQGFAKDLGESVNLLAKTSSNIIDDVNHVLVAM
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
ADGDLTQRVSQNYQGDFETLANSLNNALEKLSQALSEVRSSAVVISQASSQISSTSLSLA
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHH
EATSEQASSIEQTTAAVEEMSASITQTNQNTKVTDDIAKKSANDAIKGGESVNATVLAMS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHCCCCCCCHHHHHHH
KIAEKIGIINEISGQTNLLALNAAIEAARAGEQGMGFAVVASEVGKLAERSQAAAKEISH
HHHHHHCCHHHCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LANASLVTAEEAGQLLNQIVPSISKTAELVQDISFSSKEQAVGVQQITDAMTLVNESTQN
HHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
NAASSEELSATANEMSRQAEHLMVLVEQFRFKLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]