| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is hutH [H]
Identifier: 183220142
GI number: 183220142
Start: 744275
End: 745819
Strand: Direct
Name: hutH [H]
Synonym: LEPBI_I0730
Alternate gene names: 183220142
Gene position: 744275-745819 (Clockwise)
Preceding gene: 183220141
Following gene: 183220145
Centisome position: 20.68
GC content: 39.94
Gene sequence:
>1545_bases ATGCCCCGGTTTTGTCCATCCATGTACCTTCAATTATCCGATTTACATTCATTCGCAGATTCTGGATCGTTTTCTCACTT ACAAGAGCGAAAAAAAAGTTTGGAAGAAGAACGTGAGAGATTAGAAACAATTCTCAAAACCTCATCTGACAAACTGATTT ATGGAATCCATACAGGTTTTGGTCCTCATGCCTTTACTTCCAATGAAGAACTTCATCTCATTCAAAAATCTCTTATATAC CACCTAACAGTGGAACCTATATTGACCTTGGAAGGAACCCCTCATTCGAATCTCACTCACAAAGAAGCAAGAGTGGTTCT TTGTGCCCGACTTTTTAGTTTAGCACTCGGCGGTTCTGGGATTCGGTTTGAAACCTTAGATGTTTTGAACCAACTTTTAG AATTCGATTGTATCCCCATCCTTCCTGAAAAAGGATCTCTTTCGGCTTCTGGAGACCTAATCCCTCTCAGTTATATTCCC TTGGCTCTACTAGGTGAATCTGGATTTACAGGAAAAGGGAAGGGCTTAGGGCCCACCAAACAAAATGGGAAAACTTCAAA AATTCCTGGCCTTCCTTGGACACCCCATCCGAAAGAAGCCATCTCGCTGACGAATGGAACTAGTTTTACAACAGCCTTAC TTGGTTACCAAGTGGTGGAATTTCGAAATTTGTTTTTACAGTCCATCGAACTCTTACGGTATCTCTTCCATTACCATTCT ATTTTCCCTGATGCCTTCCATCCAGGATACCACGATCACAAACAATTCGATGGACCCAAACGGATCGCAAATTTTTTATA CCCAATCATTTCCAAAAATCCAAAATCGAAAGTAGAAGGAAAACGAATCCAAGATATTTATTCGGTGCGTTGTATCCCTC AAATCTTAGGTTCCATTTGGGATGAATTAGACTCGATTGGTTTGGTCGTAGAACAAGAGTTAAATTCATTATCCGACAAT CCGATTCTCATCTCTGAGTCAAAAAATGGAGAAATTTTACATCGTTTTGCTGAAGGTGGTGGTTTTTACGCATCCCAAGT GAGTTTTGCTGCTGATCGATTGCAAAATGCCATGGCTGTTTGGTTCACTTGGATAGACCGTTTTCTGAATTATTTAATGG AACCAAAAGAAAATGATGAGTTTCCGCTTATGTTATCGGCAAAACCTGGAACCTATGCAGGTTTATCTGGATTGGGACTG ATGGCAACTCACCTAACGGCAGAAGTGCGACGAGATAGTATGCCTGGATCAATGCAGTCGATTCCCACCAATGGAAATAA CCAAGACATTGTCCCTATGGGAGCTATCTCTGTTTTAAGAAATCGTAGAACTGTACATAGTGCGAAGAAAATACTCGCCA TTTTTAGTTATGCGATCTTCCAATCTTCTCTGTTTGCTAAAAAAAAGGAATTGGTTCCATACTTTGAATTGTTTCGCGAT TTAAATACGATGGAGGAAGATAGAAGCCTGGACTTTGAAATCCAGACTTTAATGGAAAGAATTGATAACTCTATTTCTTT TCTTGTAATGACTCCAAACGATTGA
Upstream 100 bases:
>100_bases GTTTGGTGGGTATTTAGCATATTCAATGGGAATTTTAGTTCCTGTTTTTATCCTCATCACTTTCATTTTCTTCGTCTAAG TAACAATCAAACCGGGGTCA
Downstream 100 bases:
>100_bases GTCCCAATCCTAAAACCAAACCAAATACAAGTGCAAAAATGGGAATTTGGGCTTCGGAAACATCTTTTGGCAAGATGTTT TTGGCGGTTGCAATTTGGAT
Product: histidine ammonia-lyase
Products: NA
Alternate protein names: Histidase [H]
Number of amino acids: Translated: 514; Mature: 513
Protein sequence:
>514_residues MPRFCPSMYLQLSDLHSFADSGSFSHLQERKKSLEEERERLETILKTSSDKLIYGIHTGFGPHAFTSNEELHLIQKSLIY HLTVEPILTLEGTPHSNLTHKEARVVLCARLFSLALGGSGIRFETLDVLNQLLEFDCIPILPEKGSLSASGDLIPLSYIP LALLGESGFTGKGKGLGPTKQNGKTSKIPGLPWTPHPKEAISLTNGTSFTTALLGYQVVEFRNLFLQSIELLRYLFHYHS IFPDAFHPGYHDHKQFDGPKRIANFLYPIISKNPKSKVEGKRIQDIYSVRCIPQILGSIWDELDSIGLVVEQELNSLSDN PILISESKNGEILHRFAEGGGFYASQVSFAADRLQNAMAVWFTWIDRFLNYLMEPKENDEFPLMLSAKPGTYAGLSGLGL MATHLTAEVRRDSMPGSMQSIPTNGNNQDIVPMGAISVLRNRRTVHSAKKILAIFSYAIFQSSLFAKKKELVPYFELFRD LNTMEEDRSLDFEIQTLMERIDNSISFLVMTPND
Sequences:
>Translated_514_residues MPRFCPSMYLQLSDLHSFADSGSFSHLQERKKSLEEERERLETILKTSSDKLIYGIHTGFGPHAFTSNEELHLIQKSLIY HLTVEPILTLEGTPHSNLTHKEARVVLCARLFSLALGGSGIRFETLDVLNQLLEFDCIPILPEKGSLSASGDLIPLSYIP LALLGESGFTGKGKGLGPTKQNGKTSKIPGLPWTPHPKEAISLTNGTSFTTALLGYQVVEFRNLFLQSIELLRYLFHYHS IFPDAFHPGYHDHKQFDGPKRIANFLYPIISKNPKSKVEGKRIQDIYSVRCIPQILGSIWDELDSIGLVVEQELNSLSDN PILISESKNGEILHRFAEGGGFYASQVSFAADRLQNAMAVWFTWIDRFLNYLMEPKENDEFPLMLSAKPGTYAGLSGLGL MATHLTAEVRRDSMPGSMQSIPTNGNNQDIVPMGAISVLRNRRTVHSAKKILAIFSYAIFQSSLFAKKKELVPYFELFRD LNTMEEDRSLDFEIQTLMERIDNSISFLVMTPND >Mature_513_residues PRFCPSMYLQLSDLHSFADSGSFSHLQERKKSLEEERERLETILKTSSDKLIYGIHTGFGPHAFTSNEELHLIQKSLIYH LTVEPILTLEGTPHSNLTHKEARVVLCARLFSLALGGSGIRFETLDVLNQLLEFDCIPILPEKGSLSASGDLIPLSYIPL ALLGESGFTGKGKGLGPTKQNGKTSKIPGLPWTPHPKEAISLTNGTSFTTALLGYQVVEFRNLFLQSIELLRYLFHYHSI FPDAFHPGYHDHKQFDGPKRIANFLYPIISKNPKSKVEGKRIQDIYSVRCIPQILGSIWDELDSIGLVVEQELNSLSDNP ILISESKNGEILHRFAEGGGFYASQVSFAADRLQNAMAVWFTWIDRFLNYLMEPKENDEFPLMLSAKPGTYAGLSGLGLM ATHLTAEVRRDSMPGSMQSIPTNGNNQDIVPMGAISVLRNRRTVHSAKKILAIFSYAIFQSSLFAKKKELVPYFELFRDL NTMEEDRSLDFEIQTLMERIDNSISFLVMTPND
Specific function: Unknown
COG id: COG2986
COG function: function code E; Histidine ammonia-lyase
Gene ontology:
Cell location: Cytoplasm (Potential) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the PAL/histidase family [H]
Homologues:
Organism=Homo sapiens, GI4504333, Length=458, Percent_Identity=27.5109170305677, Blast_Score=151, Evalue=2e-36, Organism=Caenorhabditis elegans, GI17567831, Length=486, Percent_Identity=28.6008230452675, Blast_Score=141, Evalue=1e-33,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005921 - InterPro: IPR008948 - InterPro: IPR001106 - InterPro: IPR022313 [H]
Pfam domain/function: PF00221 PAL [H]
EC number: =4.3.1.3 [H]
Molecular weight: Translated: 57705; Mature: 57574
Theoretical pI: Translated: 6.56; Mature: 6.56
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPRFCPSMYLQLSDLHSFADSGSFSHLQERKKSLEEERERLETILKTSSDKLIYGIHTGF CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC GPHAFTSNEELHLIQKSLIYHLTVEPILTLEGTPHSNLTHKEARVVLCARLFSLALGGSG CCCCCCCCCHHHHHHHHHHHHEEECEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC IRFETLDVLNQLLEFDCIPILPEKGSLSASGDLIPLSYIPLALLGESGFTGKGKGLGPTK CEEHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEHHHCCHHHCCCCCCCCCCCCCCCCC QNGKTSKIPGLPWTPHPKEAISLTNGTSFTTALLGYQVVEFRNLFLQSIELLRYLFHYHS CCCCCCCCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IFPDAFHPGYHDHKQFDGPKRIANFLYPIISKNPKSKVEGKRIQDIYSVRCIPQILGSIW HCCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHH DELDSIGLVVEQELNSLSDNPILISESKNGEILHRFAEGGGFYASQVSFAADRLQNAMAV HHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHCCCEEHHHHHHHHHHHHHHHHH WFTWIDRFLNYLMEPKENDEFPLMLSAKPGTYAGLSGLGLMATHLTAEVRRDSMPGSMQS HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHC IPTNGNNQDIVPMGAISVLRNRRTVHSAKKILAIFSYAIFQSSLFAKKKELVPYFELFRD CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH LNTMEEDRSLDFEIQTLMERIDNSISFLVMTPND HHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCC >Mature Secondary Structure PRFCPSMYLQLSDLHSFADSGSFSHLQERKKSLEEERERLETILKTSSDKLIYGIHTGF CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC GPHAFTSNEELHLIQKSLIYHLTVEPILTLEGTPHSNLTHKEARVVLCARLFSLALGGSG CCCCCCCCCHHHHHHHHHHHHEEECEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC IRFETLDVLNQLLEFDCIPILPEKGSLSASGDLIPLSYIPLALLGESGFTGKGKGLGPTK CEEHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEHHHCCHHHCCCCCCCCCCCCCCCCC QNGKTSKIPGLPWTPHPKEAISLTNGTSFTTALLGYQVVEFRNLFLQSIELLRYLFHYHS CCCCCCCCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IFPDAFHPGYHDHKQFDGPKRIANFLYPIISKNPKSKVEGKRIQDIYSVRCIPQILGSIW HCCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHH DELDSIGLVVEQELNSLSDNPILISESKNGEILHRFAEGGGFYASQVSFAADRLQNAMAV HHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHCCCEEHHHHHHHHHHHHHHHHH WFTWIDRFLNYLMEPKENDEFPLMLSAKPGTYAGLSGLGLMATHLTAEVRRDSMPGSMQS HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHC IPTNGNNQDIVPMGAISVLRNRRTVHSAKKILAIFSYAIFQSSLFAKKKELVPYFELFRD CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH LNTMEEDRSLDFEIQTLMERIDNSISFLVMTPND HHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA