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The map label for this gene is 183220140

Identifier: 183220140

GI number: 183220140

Start: 741925

End: 742731

Strand: Direct

Name: 183220140

Synonym: LEPBI_I0728

Alternate gene names: NA

Gene position: 741925-742731 (Clockwise)

Preceding gene: 183220134

Following gene: 183220141

Centisome position: 20.61

GC content: 41.76

Gene sequence:

>807_bases
ATGGAAGTCATTTGTAACTCTAGTTTTATTCTTTGCTCTGTCACTTGGATCGGCCATGCAACTACCCTGATTCAAATTGA
TGGACTCAATATTTTAACCGATCCCATCTGGAGTGAGAGGTGTTCCCCTTTCTCGTTTGCTGGTCCCAAACGGTACACAC
CACCAGGAATTTCCATAAATCACCTGCCAAACATTGACATAGTCATTTTATCCCATAACCATTATGACCATACAGACCTT
CCCACTTTGAAACAATTAGAAGAAAAATTCCATCCAATGGTTTTAACAGGACTAGGTAACAAAAAATTATTGTTAGGTGA
AGGTATGCATAATGTAAAGGAGATGGATTGGTGGGAAAAAATTTCTTTTGGTTCTGTTACATTCACATTTACACCGACCC
AACATTTTAGTGGGCGGAGTCTATTTGACCGCGATGAAACTCTTTGGGGGAGCTTTATGGTGGTTGGGAAAAAAGAAAAA
GTGTATTTTGCCGGAGATACAGGTTATTTCTCTCATTTTAAAGACATCGCCAGCCGGTTTGGATCCATCGACATTGCCAT
TTTGCCCATTGGAGCTACAGAACCGCGGTGGCTTATGGAACCAGTTCATATCGGTCCCACCCAAGCCGTGATGTCATTTC
TCGACCTCAAGGCAAAATTCCTCGTTCCTATGCACTACATGACCTTTGTTTTATCAGATGAACCACTCGATTCTCCTGTG
CCCCGCACAAAAGAAGCGATGAAACAATCGGGAATCTCCGAATCTGCGTTTGTTCCTTTAAAAATTGGAGAATCACGCTT
TTTTTAG

Upstream 100 bases:

>100_bases
TCGATACATCGTAGTAAGTGATTGTGCTTGGGAATCGGAAAAAGGCAATCGAAAAATGAATCCATCCGATTGTGACTAGT
CACAGTCTAAAGTAAGTGAA

Downstream 100 bases:

>100_bases
TTCCATGTGATTTCTCTTTCGGGTATGCTGTCCTAAAAAAAATAGGATGGTGAGCACGTTGAAGAAGCTTCTCACATTGA
TGGTTTTCCTGGTATGTTTG

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MEVICNSSFILCSVTWIGHATTLIQIDGLNILTDPIWSERCSPFSFAGPKRYTPPGISINHLPNIDIVILSHNHYDHTDL
PTLKQLEEKFHPMVLTGLGNKKLLLGEGMHNVKEMDWWEKISFGSVTFTFTPTQHFSGRSLFDRDETLWGSFMVVGKKEK
VYFAGDTGYFSHFKDIASRFGSIDIAILPIGATEPRWLMEPVHIGPTQAVMSFLDLKAKFLVPMHYMTFVLSDEPLDSPV
PRTKEAMKQSGISESAFVPLKIGESRFF

Sequences:

>Translated_268_residues
MEVICNSSFILCSVTWIGHATTLIQIDGLNILTDPIWSERCSPFSFAGPKRYTPPGISINHLPNIDIVILSHNHYDHTDL
PTLKQLEEKFHPMVLTGLGNKKLLLGEGMHNVKEMDWWEKISFGSVTFTFTPTQHFSGRSLFDRDETLWGSFMVVGKKEK
VYFAGDTGYFSHFKDIASRFGSIDIAILPIGATEPRWLMEPVHIGPTQAVMSFLDLKAKFLVPMHYMTFVLSDEPLDSPV
PRTKEAMKQSGISESAFVPLKIGESRFF
>Mature_268_residues
MEVICNSSFILCSVTWIGHATTLIQIDGLNILTDPIWSERCSPFSFAGPKRYTPPGISINHLPNIDIVILSHNHYDHTDL
PTLKQLEEKFHPMVLTGLGNKKLLLGEGMHNVKEMDWWEKISFGSVTFTFTPTQHFSGRSLFDRDETLWGSFMVVGKKEK
VYFAGDTGYFSHFKDIASRFGSIDIAILPIGATEPRWLMEPVHIGPTQAVMSFLDLKAKFLVPMHYMTFVLSDEPLDSPV
PRTKEAMKQSGISESAFVPLKIGESRFF

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=260, Percent_Identity=42.6923076923077, Blast_Score=218, Evalue=3e-57,
Organism=Homo sapiens, GI170932481, Length=260, Percent_Identity=42.6923076923077, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17543102, Length=266, Percent_Identity=36.4661654135338, Blast_Score=187, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17543100, Length=266, Percent_Identity=36.4661654135338, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI25148824, Length=266, Percent_Identity=36.4661654135338, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17543104, Length=265, Percent_Identity=35.8490566037736, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6325154, Length=261, Percent_Identity=34.4827586206897, Blast_Score=151, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30257; Mature: 30257

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVICNSSFILCSVTWIGHATTLIQIDGLNILTDPIWSERCSPFSFAGPKRYTPPGISIN
CEEEECCCEEEEEEEECCCEEEEEEECCCEEECCCHHHHCCCCCCCCCCCCCCCCCCEEC
HLPNIDIVILSHNHYDHTDLPTLKQLEEKFHPMVLTGLGNKKLLLGEGMHNVKEMDWWEK
CCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCCEEEECCCCHHHHHCCHHHH
ISFGSVTFTFTPTQHFSGRSLFDRDETLWGSFMVVGKKEKVYFAGDTGYFSHFKDIASRF
CCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHH
GSIDIAILPIGATEPRWLMEPVHIGPTQAVMSFLDLKAKFLVPMHYMTFVLSDEPLDSPV
CCEEEEEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHEEEHEEHEEEEECCCCCCCCC
PRTKEAMKQSGISESAFVPLKIGESRFF
CHHHHHHHHCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MEVICNSSFILCSVTWIGHATTLIQIDGLNILTDPIWSERCSPFSFAGPKRYTPPGISIN
CEEEECCCEEEEEEEECCCEEEEEEECCCEEECCCHHHHCCCCCCCCCCCCCCCCCCEEC
HLPNIDIVILSHNHYDHTDLPTLKQLEEKFHPMVLTGLGNKKLLLGEGMHNVKEMDWWEK
CCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCCEEEECCCCHHHHHCCHHHH
ISFGSVTFTFTPTQHFSGRSLFDRDETLWGSFMVVGKKEKVYFAGDTGYFSHFKDIASRF
CCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHH
GSIDIAILPIGATEPRWLMEPVHIGPTQAVMSFLDLKAKFLVPMHYMTFVLSDEPLDSPV
CCEEEEEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHEEEHEEHEEEEECCCCCCCCC
PRTKEAMKQSGISESAFVPLKIGESRFF
CHHHHHHHHCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]