Click here to switch to the map view.

The map label for this gene is aer [H]

Identifier: 183220012

GI number: 183220012

Start: 598089

End: 599780

Strand: Direct

Name: aer [H]

Synonym: LEPBI_I0595

Alternate gene names: 183220012

Gene position: 598089-599780 (Clockwise)

Preceding gene: 183220006

Following gene: 183220013

Centisome position: 16.62

GC content: 38.59

Gene sequence:

>1692_bases
ATGCGCCAGAATCTTCCTATTACCAATCATGAAGTGGAATTCCAAGAAGGAACAAAGATCACTTCCAAAACGGATTTGAA
AGGGATCATCACTTATGTCAATGAAGACTTCTTAAAAATTAGTGGATATACGAATGAAGAGTTGATTGGACAACCTCACA
ACCTCATCCGTCATCCAGAGATGCCACAAGAAGCATTCCGTGACCTTTGGGAGACAGTGAAGGCCCAAAACTCATGGGTT
GGCCTTGTCAAAAATCGATGCAAAAATGGGGATTTTTATTGGGTCGATGCCAATGTATCTCCCATTTACGAAGATGGAAA
ACACATCGGTTATATGTCGGTTCGCACAAAGGCAACCAGGGAGCAAATCCAAAACGCAGAAATATTATATGCAAAAATGA
ATCTCGGGAACTGGCAAAAAAGTTCTAAACTAAAATTTTTATCTGCTCTTTCTTCTCGCACCGTTTATTTGATACAAACG
ATCGTTAGTTTACTTTTGTTAGTTGGATTTTTTTCTCTCCAAGTTTTTGAATTACCCGATTCTCAAAAACCCATCTTATT
TGGAATTGGATTTGTTCTTTTTACTATCACTTCTTTATTTGGGTATTGGAAAATTGCAAAAAATAGACATTCTTTTTTAA
AGGTCATCCAATACCTACAAAACTTATACAAAGGTCATTTGAAATTCGATGTAGAGTTAGAAAATGGTGGTGATTACGAG
GAAGTTTTACATCTCCTTAAAAAAACTCAATTTGAATTTCGTGGGATGATTTCGCAACTCATTGGTAACGCTGAGATCGT
CAAATCGCAAATTAAGGGTCTCACAAAAGCCGTCGAACACATCCATGTTGCGTTCCAAGAATTATCACTGGCGATGCATT
CCCTCGCTGATTCTAGTAATGTCACTCGCGAAAGTTCTGAAAGTATCTTCCACCAAATGGATGCACTCAACCACCTCATC
CAAAGCATACGATCCGAGTCCATTGCTGTTAAGTTAGAATCAACAACTGCCCACCAGATTGCTATGGAAGGAAAAAATCG
TTCGGACAAAGCAATGGCTCAATTCTTTAAAGCCAAAAATCAAATTTTCAAAACTTCTGAATCCATCAAAGATTTGGGAG
AAAAAACGAAAGCCATCCGTAAAATTACAGAAACCATTGCCGCCATCTCTGAAAAAACCAACTTACTTTCGTTAAATGCA
TCAATTGAATCTGCTAGAGCTGGAGATGCAGGGAAGGGTTTTGCGGTTGTTGCGGGTGAGGTTGGACTTCTTGCGGAACA
ATCGAAAAAATCTGCCAAAGAAATTTCAGTTTTTATCAATGAACTAACATCAAAGATATTACAAACCGTAACAGACATTG
AAGAAGGATTGAGCGAAGTGGAACTTGGTTCTAGTGAATTTGAAACAGTGCAAACAGAGATGGAAAAGATTCTAACAAAT
TCTGTTGTTACGAAAGAAAGTTCCGAAAAAATTAGCAGTTCGACGGAAGGAACGCAAGAAAAATCAACAAGTGTTCTTTC
CAATATGGAAAAAATCCAAAACCAATTGACTCATACTTCTTCGATTGTAGAAGAATTATCTGCCGCCGCAAGCGAACAAC
AACATACGGTTGCGGCCATCGAAGAATCCATTTCCAATTTGGACAAGGTGGCGGACAGGCTTGATTCCGTTGCCTTTCGG
TTTCAGTTTTAG

Upstream 100 bases:

>100_bases
TTGCAAAAGAATCATTCTTAGTTTGATTCTATTTTACTTGCTCCGTAAGGGCTTTACCTAAATACTTTCTATAGCTACTG
TATACTGGAACCAATCATCC

Downstream 100 bases:

>100_bases
TAAGGATCTAATTCAATCTAAAGGATTATTTGATGGCAACACAGAACCCAGAAACCAAGTCGAAGATGAGTTTCCATGTG
GAGACAACAAGACTCGATTC

Product: putative aerotaxis sensor receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MRQNLPITNHEVEFQEGTKITSKTDLKGIITYVNEDFLKISGYTNEELIGQPHNLIRHPEMPQEAFRDLWETVKAQNSWV
GLVKNRCKNGDFYWVDANVSPIYEDGKHIGYMSVRTKATREQIQNAEILYAKMNLGNWQKSSKLKFLSALSSRTVYLIQT
IVSLLLLVGFFSLQVFELPDSQKPILFGIGFVLFTITSLFGYWKIAKNRHSFLKVIQYLQNLYKGHLKFDVELENGGDYE
EVLHLLKKTQFEFRGMISQLIGNAEIVKSQIKGLTKAVEHIHVAFQELSLAMHSLADSSNVTRESSESIFHQMDALNHLI
QSIRSESIAVKLESTTAHQIAMEGKNRSDKAMAQFFKAKNQIFKTSESIKDLGEKTKAIRKITETIAAISEKTNLLSLNA
SIESARAGDAGKGFAVVAGEVGLLAEQSKKSAKEISVFINELTSKILQTVTDIEEGLSEVELGSSEFETVQTEMEKILTN
SVVTKESSEKISSSTEGTQEKSTSVLSNMEKIQNQLTHTSSIVEELSAAASEQQHTVAAIEESISNLDKVADRLDSVAFR
FQF

Sequences:

>Translated_563_residues
MRQNLPITNHEVEFQEGTKITSKTDLKGIITYVNEDFLKISGYTNEELIGQPHNLIRHPEMPQEAFRDLWETVKAQNSWV
GLVKNRCKNGDFYWVDANVSPIYEDGKHIGYMSVRTKATREQIQNAEILYAKMNLGNWQKSSKLKFLSALSSRTVYLIQT
IVSLLLLVGFFSLQVFELPDSQKPILFGIGFVLFTITSLFGYWKIAKNRHSFLKVIQYLQNLYKGHLKFDVELENGGDYE
EVLHLLKKTQFEFRGMISQLIGNAEIVKSQIKGLTKAVEHIHVAFQELSLAMHSLADSSNVTRESSESIFHQMDALNHLI
QSIRSESIAVKLESTTAHQIAMEGKNRSDKAMAQFFKAKNQIFKTSESIKDLGEKTKAIRKITETIAAISEKTNLLSLNA
SIESARAGDAGKGFAVVAGEVGLLAEQSKKSAKEISVFINELTSKILQTVTDIEEGLSEVELGSSEFETVQTEMEKILTN
SVVTKESSEKISSSTEGTQEKSTSVLSNMEKIQNQLTHTSSIVEELSAAASEQQHTVAAIEESISNLDKVADRLDSVAFR
FQF
>Mature_563_residues
MRQNLPITNHEVEFQEGTKITSKTDLKGIITYVNEDFLKISGYTNEELIGQPHNLIRHPEMPQEAFRDLWETVKAQNSWV
GLVKNRCKNGDFYWVDANVSPIYEDGKHIGYMSVRTKATREQIQNAEILYAKMNLGNWQKSSKLKFLSALSSRTVYLIQT
IVSLLLLVGFFSLQVFELPDSQKPILFGIGFVLFTITSLFGYWKIAKNRHSFLKVIQYLQNLYKGHLKFDVELENGGDYE
EVLHLLKKTQFEFRGMISQLIGNAEIVKSQIKGLTKAVEHIHVAFQELSLAMHSLADSSNVTRESSESIFHQMDALNHLI
QSIRSESIAVKLESTTAHQIAMEGKNRSDKAMAQFFKAKNQIFKTSESIKDLGEKTKAIRKITETIAAISEKTNLLSLNA
SIESARAGDAGKGFAVVAGEVGLLAEQSKKSAKEISVFINELTSKILQTVTDIEEGLSEVELGSSEFETVQTEMEKILTN
SVVTKESSEKISSSTEGTQEKSTSVLSNMEKIQNQLTHTSSIVEELSAAASEQQHTVAAIEESISNLDKVADRLDSVAFR
FQF

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=555, Percent_Identity=29.5495495495495, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1787690, Length=270, Percent_Identity=31.4814814814815, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788195, Length=301, Percent_Identity=26.578073089701, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788194, Length=319, Percent_Identity=25.0783699059561, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI2367378, Length=119, Percent_Identity=36.1344537815126, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 63083; Mature: 63083

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQNLPITNHEVEFQEGTKITSKTDLKGIITYVNEDFLKISGYTNEELIGQPHNLIRHPE
CCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCHHHCCCCHHHCCCCC
MPQEAFRDLWETVKAQNSWVGLVKNRCKNGDFYWVDANVSPIYEDGKHIGYMSVRTKATR
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCHHHCCCEEEEEHHHHHHHH
EQIQNAEILYAKMNLGNWQKSSKLKFLSALSSRTVYLIQTIVSLLLLVGFFSLQVFELPD
HHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCC
SQKPILFGIGFVLFTITSLFGYWKIAKNRHSFLKVIQYLQNLYKGHLKFDVELENGGDYE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHH
EVLHLLKKTQFEFRGMISQLIGNAEIVKSQIKGLTKAVEHIHVAFQELSLAMHSLADSSN
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VTRESSESIFHQMDALNHLIQSIRSESIAVKLESTTAHQIAMEGKNRSDKAMAQFFKAKN
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHH
QIFKTSESIKDLGEKTKAIRKITETIAAISEKTNLLSLNASIESARAGDAGKGFAVVAGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCCCCEEEEECC
VGLLAEQSKKSAKEISVFINELTSKILQTVTDIEEGLSEVELGSSEFETVQTEMEKILTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SVVTKESSEKISSSTEGTQEKSTSVLSNMEKIQNQLTHTSSIVEELSAAASEQQHTVAAI
HHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EESISNLDKVADRLDSVAFRFQF
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRQNLPITNHEVEFQEGTKITSKTDLKGIITYVNEDFLKISGYTNEELIGQPHNLIRHPE
CCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCHHHCCCCHHHCCCCC
MPQEAFRDLWETVKAQNSWVGLVKNRCKNGDFYWVDANVSPIYEDGKHIGYMSVRTKATR
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCHHHCCCEEEEEHHHHHHHH
EQIQNAEILYAKMNLGNWQKSSKLKFLSALSSRTVYLIQTIVSLLLLVGFFSLQVFELPD
HHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCC
SQKPILFGIGFVLFTITSLFGYWKIAKNRHSFLKVIQYLQNLYKGHLKFDVELENGGDYE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHH
EVLHLLKKTQFEFRGMISQLIGNAEIVKSQIKGLTKAVEHIHVAFQELSLAMHSLADSSN
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VTRESSESIFHQMDALNHLIQSIRSESIAVKLESTTAHQIAMEGKNRSDKAMAQFFKAKN
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHH
QIFKTSESIKDLGEKTKAIRKITETIAAISEKTNLLSLNASIESARAGDAGKGFAVVAGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCCCCEEEEECC
VGLLAEQSKKSAKEISVFINELTSKILQTVTDIEEGLSEVELGSSEFETVQTEMEKILTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SVVTKESSEKISSSTEGTQEKSTSVLSNMEKIQNQLTHTSSIVEELSAAASEQQHTVAAI
HHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EESISNLDKVADRLDSVAFRFQF
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]