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The map label for this gene is ftsA1 [H]

Identifier: 183219739

GI number: 183219739

Start: 315141

End: 316379

Strand: Direct

Name: ftsA1 [H]

Synonym: LEPBI_I0315

Alternate gene names: 183219739

Gene position: 315141-316379 (Clockwise)

Preceding gene: 183219738

Following gene: 183219740

Centisome position: 8.75

GC content: 42.7

Gene sequence:

>1239_bases
ATGATAGAAGATGATTCCCCGATCATAACTGCATTGGACCTTGGTTCTTCTCTTGTGAAAGTTGTCATCGGGCGACTCGT
GGGAGATCATGAAATTGAAATCATCGGTACCGGTGTTTATCCTTCCACAGGGATCAAAAATGGATCCATTGTTAATATAG
AAACAACCACAAAGTCCATCATAGAGGCGTTTGGTGATGCAGAACTGATGGCAGGACAAGAGATCACTTCTGTCGTCGTG
AATGTTTCTGGAAAATCAGTTCATGGATTTAATGAAAAAGGTATCATCGCTGTTACGAATCGAGAACGAATTGTCACGGA
GATGGATATCATGCGAGTCGTGGAAGCCGCACAAGCAGTCCATGTTCCCAATGACCAACAAGTCATCCATGTACTCACAA
AAGAATTTAAGGTTGATGACCAAGTGAACATCAAAGATCCCATCGGGATGACGGGTGTTCGGTTAGAAGCAGAGGTCCAC
ATTGTATCTTGTGGGAACACTGCTCTCAATAACATTGATCGATGTGTGGAACAATCAGGTCTTTTACAAATGGATAAGGT
ATTGTCTAGCCTTGCTTCTTCCGAAGCCATATTAACTGCTGGTGAAAAAGACTTAGGGACAGCAGTGATTGATATTGGGG
CTGGAATTTGTGACATCATCATCTATGTAGATGGCGGAATCGCTTATTCATCCGTTGTTCCATTTGGTGGATTCCACATC
ACAAGTGATATCTCCATCGGATTAAAAACAACAGTAGAAACAGCAGAAATCATCAAAAAACGGTATGGCCATACAAGAAT
TGATATGGTAGATCCAACGGAAAAATTTGAAATTCCATCCATATCCGGAAGGCCGGCCAGGTCAGTATTTCGACAAGAAC
TTGTTGAAATCTTGGAACCACGAGTTCGCGAAATCTTAGAGATGATCGACCATGAACTCATTCGATCAGGGTATAAGTCG
AGTTTGGCGGGTGGAGTGATCCTCACGGGAGGGACATCTCTTTTGCAAGGAATTGAAGTTACGGCTGAGGAAGTATTCCG
ATTGTCAGTGGGTCGTGCCAAACCAGCGGGACTTGGTGGACTTGTGGAACGAATTGCAAGCCCTGAATATGCAACTGCTG
TAGGATTAATTAAATATAGTTCCAAAATACAAAATTTAGAACAAAGAAACATGCATTCCGTTTCCGATGGAGAAGGATGG
ATGAAGAAGGTTCGTCGTTGGATGGAGAATAATCTCTAA

Upstream 100 bases:

>100_bases
GTTTTTCGAAAATTATATGCATCCCTTGCTTATATGGAAGCTGAATCCATCAAAGCAGTCTCTATTGATTTAAGGGGAGA
AGACGCAGTTTACCATTAAT

Downstream 100 bases:

>100_bases
GGAAAAGTGAATGTTATACCTAGAAGAAGAAAAAACTAGCCCAGCCATTATCAAAGTCATAGGAGTTGGTGGTGGTGGAA
TGAATGCCGTCACTCGTATG

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MIEDDSPIITALDLGSSLVKVVIGRLVGDHEIEIIGTGVYPSTGIKNGSIVNIETTTKSIIEAFGDAELMAGQEITSVVV
NVSGKSVHGFNEKGIIAVTNRERIVTEMDIMRVVEAAQAVHVPNDQQVIHVLTKEFKVDDQVNIKDPIGMTGVRLEAEVH
IVSCGNTALNNIDRCVEQSGLLQMDKVLSSLASSEAILTAGEKDLGTAVIDIGAGICDIIIYVDGGIAYSSVVPFGGFHI
TSDISIGLKTTVETAEIIKKRYGHTRIDMVDPTEKFEIPSISGRPARSVFRQELVEILEPRVREILEMIDHELIRSGYKS
SLAGGVILTGGTSLLQGIEVTAEEVFRLSVGRAKPAGLGGLVERIASPEYATAVGLIKYSSKIQNLEQRNMHSVSDGEGW
MKKVRRWMENNL

Sequences:

>Translated_412_residues
MIEDDSPIITALDLGSSLVKVVIGRLVGDHEIEIIGTGVYPSTGIKNGSIVNIETTTKSIIEAFGDAELMAGQEITSVVV
NVSGKSVHGFNEKGIIAVTNRERIVTEMDIMRVVEAAQAVHVPNDQQVIHVLTKEFKVDDQVNIKDPIGMTGVRLEAEVH
IVSCGNTALNNIDRCVEQSGLLQMDKVLSSLASSEAILTAGEKDLGTAVIDIGAGICDIIIYVDGGIAYSSVVPFGGFHI
TSDISIGLKTTVETAEIIKKRYGHTRIDMVDPTEKFEIPSISGRPARSVFRQELVEILEPRVREILEMIDHELIRSGYKS
SLAGGVILTGGTSLLQGIEVTAEEVFRLSVGRAKPAGLGGLVERIASPEYATAVGLIKYSSKIQNLEQRNMHSVSDGEGW
MKKVRRWMENNL
>Mature_412_residues
MIEDDSPIITALDLGSSLVKVVIGRLVGDHEIEIIGTGVYPSTGIKNGSIVNIETTTKSIIEAFGDAELMAGQEITSVVV
NVSGKSVHGFNEKGIIAVTNRERIVTEMDIMRVVEAAQAVHVPNDQQVIHVLTKEFKVDDQVNIKDPIGMTGVRLEAEVH
IVSCGNTALNNIDRCVEQSGLLQMDKVLSSLASSEAILTAGEKDLGTAVIDIGAGICDIIIYVDGGIAYSSVVPFGGFHI
TSDISIGLKTTVETAEIIKKRYGHTRIDMVDPTEKFEIPSISGRPARSVFRQELVEILEPRVREILEMIDHELIRSGYKS
SLAGGVILTGGTSLLQGIEVTAEEVFRLSVGRAKPAGLGGLVERIASPEYATAVGLIKYSSKIQNLEQRNMHSVSDGEGW
MKKVRRWMENNL

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=420, Percent_Identity=35.2380952380952, Blast_Score=282, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 44531; Mature: 44531

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEDDSPIITALDLGSSLVKVVIGRLVGDHEIEIIGTGVYPSTGIKNGSIVNIETTTKSI
CCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEHHHHHH
IEAFGDAELMAGQEITSVVVNVSGKSVHGFNEKGIIAVTNRERIVTEMDIMRVVEAAQAV
HHHHCCHHHHCCHHEEEEEEECCCCEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
HVPNDQQVIHVLTKEFKVDDQVNIKDPIGMTGVRLEAEVHIVSCGNTALNNIDRCVEQSG
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHCC
LLQMDKVLSSLASSEAILTAGEKDLGTAVIDIGAGICDIIIYVDGGIAYSSVVPFGGFHI
CHHHHHHHHHHHCCCEEEECCCHHHCHHHHHHCCCEEEEEEEECCCEEEHHCCCCCCEEE
TSDISIGLKTTVETAEIIKKRYGHTRIDMVDPTEKFEIPSISGRPARSVFRQELVEILEP
ECCCEECCHHHHHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHHH
RVREILEMIDHELIRSGYKSSLAGGVILTGGTSLLQGIEVTAEEVFRLSVGRAKPAGLGG
HHHHHHHHHHHHHHHCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LVERIASPEYATAVGLIKYSSKIQNLEQRNMHSVSDGEGWMKKVRRWMENNL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIEDDSPIITALDLGSSLVKVVIGRLVGDHEIEIIGTGVYPSTGIKNGSIVNIETTTKSI
CCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEHHHHHH
IEAFGDAELMAGQEITSVVVNVSGKSVHGFNEKGIIAVTNRERIVTEMDIMRVVEAAQAV
HHHHCCHHHHCCHHEEEEEEECCCCEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
HVPNDQQVIHVLTKEFKVDDQVNIKDPIGMTGVRLEAEVHIVSCGNTALNNIDRCVEQSG
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHCC
LLQMDKVLSSLASSEAILTAGEKDLGTAVIDIGAGICDIIIYVDGGIAYSSVVPFGGFHI
CHHHHHHHHHHHCCCEEEECCCHHHCHHHHHHCCCEEEEEEEECCCEEEHHCCCCCCEEE
TSDISIGLKTTVETAEIIKKRYGHTRIDMVDPTEKFEIPSISGRPARSVFRQELVEILEP
ECCCEECCHHHHHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHHH
RVREILEMIDHELIRSGYKSSLAGGVILTGGTSLLQGIEVTAEEVFRLSVGRAKPAGLGG
HHHHHHHHHHHHHHHCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LVERIASPEYATAVGLIKYSSKIQNLEQRNMHSVSDGEGWMKKVRRWMENNL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]