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The map label for this gene is sdhB [H]

Identifier: 18311605

GI number: 18311605

Start: 2998572

End: 2999252

Strand: Direct

Name: sdhB [H]

Synonym: CPE2623

Alternate gene names: 18311605

Gene position: 2998572-2999252 (Clockwise)

Preceding gene: 18311597

Following gene: 18311606

Centisome position: 98.92

GC content: 33.19

Gene sequence:

>681_bases
ATGAATACATATGGTGTTTTCGATATCCTTGGACCAATTATGATTGGACCATCTAGCTCTCATACTGCAGGTGCTGCTAG
ACTTGGAAAAGTAGCTAGAGCAATCTGTGGTAAACCAATGAAAAAAGTTACTTTTCTTTTACACGGTTCTTTTGGCAAAA
CTTATAAAGGTCATGGTACAGATAAAGCTTTAGTAGCAGGTATCCTTGGAATGGAACCTTCTGATACACACCTTAGAAAT
TCTTTAGAAATAGCAAAAGAAAAAAATATTGAAATAGAGTTTAAAGAAGTTGATTTAGGAGATGCACATCCTAATACAGT
TAAATTTATAATTGAAGATATTGATGGTGTTTTTCATGAAATAGTAGGATCATCAATAGGTGGTGGAAGTATTAAAATTA
CTGAGGTAAATGGTAGCGTTGTTGAATTTACTGGTGAATACCCAACACTAATAATCTCACATAAAGATGTTCCTGGAGCT
GTATCTAAAGTAACAGCCATAGTTTATGAGCATAATATTAATATAGCTTTCATGAAAGTCTTTAGAACAGAAAGAGGAAA
GGCTGCAAGAATGGTCTTTGAAATGGATAGCCCTATTACAAAGGACATTATTGATGAAATTAAGAAAGTTGAAGCTGTTG
AAAAACTAGTTGTTATAAACCCAGTAAAGGAGGATATTTAG

Upstream 100 bases:

>100_bases
ATTTTGATTTTTAAAAATGTTATACTATATTTAACGAAAGAATTACTTAATTAGACACTAAAAATCTTATTTTATTAAAT
ATAACAAAGGAGGATAAAAA

Downstream 100 bases:

>100_bases
ATGATTGCAAGAAGTGGTGCTGAATTATTAGAAATATGTAGAGAGAATAATTTCTCCTTAGCTGAATACGCTATTCAATA
TGAAATGGAAAGTAAAAACT

Product: L-serine dehydratase beta subunit

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MNTYGVFDILGPIMIGPSSSHTAGAARLGKVARAICGKPMKKVTFLLHGSFGKTYKGHGTDKALVAGILGMEPSDTHLRN
SLEIAKEKNIEIEFKEVDLGDAHPNTVKFIIEDIDGVFHEIVGSSIGGGSIKITEVNGSVVEFTGEYPTLIISHKDVPGA
VSKVTAIVYEHNINIAFMKVFRTERGKAARMVFEMDSPITKDIIDEIKKVEAVEKLVVINPVKEDI

Sequences:

>Translated_226_residues
MNTYGVFDILGPIMIGPSSSHTAGAARLGKVARAICGKPMKKVTFLLHGSFGKTYKGHGTDKALVAGILGMEPSDTHLRN
SLEIAKEKNIEIEFKEVDLGDAHPNTVKFIIEDIDGVFHEIVGSSIGGGSIKITEVNGSVVEFTGEYPTLIISHKDVPGA
VSKVTAIVYEHNINIAFMKVFRTERGKAARMVFEMDSPITKDIIDEIKKVEAVEKLVVINPVKEDI
>Mature_226_residues
MNTYGVFDILGPIMIGPSSSHTAGAARLGKVARAICGKPMKKVTFLLHGSFGKTYKGHGTDKALVAGILGMEPSDTHLRN
SLEIAKEKNIEIEFKEVDLGDAHPNTVKFIIEDIDGVFHEIVGSSIGGGSIKITEVNGSVVEFTGEYPTLIISHKDVPGA
VSKVTAIVYEHNINIAFMKVFRTERGKAARMVFEMDSPITKDIIDEIKKVEAVEKLVVINPVKEDI

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR004643
- InterPro:   IPR005131 [H]

Pfam domain/function: PF01842 ACT; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 24518; Mature: 24518

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTYGVFDILGPIMIGPSSSHTAGAARLGKVARAICGKPMKKVTFLLHGSFGKTYKGHGT
CCCCCHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCCCC
DKALVAGILGMEPSDTHLRNSLEIAKEKNIEIEFKEVDLGDAHPNTVKFIIEDIDGVFHE
CHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
IVGSSIGGGSIKITEVNGSVVEFTGEYPTLIISHKDVPGAVSKVTAIVYEHNINIAFMKV
HHCCCCCCCEEEEEEECCCEEEEECCCCEEEEECCCCCCHHHHHEEEEEECCCCEEEEEE
FRTERGKAARMVFEMDSPITKDIIDEIKKVEAVEKLVVINPVKEDI
ECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEECCHHHCC
>Mature Secondary Structure
MNTYGVFDILGPIMIGPSSSHTAGAARLGKVARAICGKPMKKVTFLLHGSFGKTYKGHGT
CCCCCHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCCCC
DKALVAGILGMEPSDTHLRNSLEIAKEKNIEIEFKEVDLGDAHPNTVKFIIEDIDGVFHE
CHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
IVGSSIGGGSIKITEVNGSVVEFTGEYPTLIISHKDVPGAVSKVTAIVYEHNINIAFMKV
HHCCCCCCCEEEEEEECCCEEEEECCCCEEEEECCCCCCHHHHHEEEEEECCCCEEEEEE
FRTERGKAARMVFEMDSPITKDIIDEIKKVEAVEKLVVINPVKEDI
ECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]