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The map label for this gene is glpA [C]

Identifier: 18311533

GI number: 18311533

Start: 2921209

End: 2922639

Strand: Reverse

Name: glpA [C]

Synonym: CPE2551

Alternate gene names: 18311533

Gene position: 2922639-2921209 (Counterclockwise)

Preceding gene: 18311534

Following gene: 18311532

Centisome position: 96.41

GC content: 32.08

Gene sequence:

>1431_bases
ATGATTTATGATGTAGCAATTATAGGATCTGGAGTAATAGGTGGAGCAATATTTAGAGAATTAACAAAGTATAATTTAAA
GGTTGTAGAATTAGAAAAAGAAAATGACGTTGCTATGGGAGCATCTAAGGCAAATTCAGCAATTGTCCATTCAGGATATG
ATCCTGAACCAGGAACATTAATGGCAAAATACAATGTTGAAGGAAATAAGATGTTTGATAAGCTTTGTAAAGACTTATCA
GTTCCTTTTAAGAGAAATGGATCATTAATTATAGGTTTTGATGAAGATGACCAAAAAGAATTAGAGGTTTTATATAATAG
AGGAATTAAAAATGGAGTAGAAGGAGTAAAACTTTTATCAGCAGAAGAAGTTTTAGAAATGGAACCAAACTTAAATAAAG
ATGTAAAGGGAGCTTTATTCTGCCCAACAGGAGGAATTGTTGGAGCATATGAATTTACTATAGCTCTTTCAGAAAATGCT
ATAGATAATGGAGGAGAATTAAGACTAAACTCTAAAGTTGTTGGTATTGAAAAAGATGAAAACTTTAAAATAAAACTTGA
AAATGGGGATGTAGTAGAAGCTAGATTTGTAGTAAACGCAGCAGGTATTTATGCTGATAAGATTCACAATATGGTTTGTG
AGGAAGACTTTAAGATAACTCCTAGAAAAGGTGAATACTATGTTTTAGATAAGAGCCAAGGAAGATTATTTGAAAAGACA
ATATTCCAATGCCCAACTAAACTTGGAAAAGGGGTTTTAGTTACTCCAACAGTTCATGGAAATTTATTAGTTGGTCCAGA
TGCTATTGATACTTGTGATAAAGATTCAGTTTCTACAGAGTATGATGGATTAGCTAAGGTTAGAGAAGTTTCTTTAAAAA
CAACTAACAAAGTTAATTTTAGAGAAAATATTAGAAACTTTGCAGGACTTCGTGCTATAGCTGATAAGCCTGACTTCATA
ATCGGAGAAGCTAAAGATGTAAAAGGATTCTTTGATGTAGCAGGAATAAAATCACCAGGGTTAAGTTCAGCGCCAGCTAT
TGCAGTGGATGTAGTTAAAATGCTTGGTGAAAGTGGACTAGCTTTAGAGAAAAAAGATAATTTCAATGAAAAAAGAGAAC
AAGTACACTTTATAGAACTTTCTCCAGAAGAAAAAGCAAATTTAATTAAAAAAGATAGTAGATATGGAAGAATAATTTGC
AGATGTGAAAATATAACTGAGGGAGAGATTGTTGATAGTATAAATAGAACTTTAGGAGCTAGAACTATTGATGGAGTTAA
GAGAAGATGTCGTCCTGGTTGTGGAAGATGTCAAGGTGGTTTCTGTGGACCTAGAGTTCAAGAAATAATATCTCGTGAAA
CTGGAATGAATATAGAAGAAGTGCTTTTAGATAAAAATGGTTCATATATAATAAGTGGAAAAACAAAGTAG

Upstream 100 bases:

>100_bases
TTTGTGTGTAAGAGAGAAGAGAGCTAGACACAAAAAGGATATTCTTATGTCTTTTTTGAGTTTAGTTCTTTTTTATTTTT
AAAAAAGGGAGCGATATTTA

Downstream 100 bases:

>100_bases
GAGGATTTAGTTATGAAATATGATTTAGTAGTTGTAGGTGGAGGCCCAGCAGGATTAGCAGCAGCTTATGAAGCTCATGA
AAATGGAGTAGAAAAAATAT

Product: glycerol-3-phosphate dehydrogenase

Products: glycerone phosphate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MIYDVAIIGSGVIGGAIFRELTKYNLKVVELEKENDVAMGASKANSAIVHSGYDPEPGTLMAKYNVEGNKMFDKLCKDLS
VPFKRNGSLIIGFDEDDQKELEVLYNRGIKNGVEGVKLLSAEEVLEMEPNLNKDVKGALFCPTGGIVGAYEFTIALSENA
IDNGGELRLNSKVVGIEKDENFKIKLENGDVVEARFVVNAAGIYADKIHNMVCEEDFKITPRKGEYYVLDKSQGRLFEKT
IFQCPTKLGKGVLVTPTVHGNLLVGPDAIDTCDKDSVSTEYDGLAKVREVSLKTTNKVNFRENIRNFAGLRAIADKPDFI
IGEAKDVKGFFDVAGIKSPGLSSAPAIAVDVVKMLGESGLALEKKDNFNEKREQVHFIELSPEEKANLIKKDSRYGRIIC
RCENITEGEIVDSINRTLGARTIDGVKRRCRPGCGRCQGGFCGPRVQEIISRETGMNIEEVLLDKNGSYIISGKTK

Sequences:

>Translated_476_residues
MIYDVAIIGSGVIGGAIFRELTKYNLKVVELEKENDVAMGASKANSAIVHSGYDPEPGTLMAKYNVEGNKMFDKLCKDLS
VPFKRNGSLIIGFDEDDQKELEVLYNRGIKNGVEGVKLLSAEEVLEMEPNLNKDVKGALFCPTGGIVGAYEFTIALSENA
IDNGGELRLNSKVVGIEKDENFKIKLENGDVVEARFVVNAAGIYADKIHNMVCEEDFKITPRKGEYYVLDKSQGRLFEKT
IFQCPTKLGKGVLVTPTVHGNLLVGPDAIDTCDKDSVSTEYDGLAKVREVSLKTTNKVNFRENIRNFAGLRAIADKPDFI
IGEAKDVKGFFDVAGIKSPGLSSAPAIAVDVVKMLGESGLALEKKDNFNEKREQVHFIELSPEEKANLIKKDSRYGRIIC
RCENITEGEIVDSINRTLGARTIDGVKRRCRPGCGRCQGGFCGPRVQEIISRETGMNIEEVLLDKNGSYIISGKTK
>Mature_476_residues
MIYDVAIIGSGVIGGAIFRELTKYNLKVVELEKENDVAMGASKANSAIVHSGYDPEPGTLMAKYNVEGNKMFDKLCKDLS
VPFKRNGSLIIGFDEDDQKELEVLYNRGIKNGVEGVKLLSAEEVLEMEPNLNKDVKGALFCPTGGIVGAYEFTIALSENA
IDNGGELRLNSKVVGIEKDENFKIKLENGDVVEARFVVNAAGIYADKIHNMVCEEDFKITPRKGEYYVLDKSQGRLFEKT
IFQCPTKLGKGVLVTPTVHGNLLVGPDAIDTCDKDSVSTEYDGLAKVREVSLKTTNKVNFRENIRNFAGLRAIADKPDFI
IGEAKDVKGFFDVAGIKSPGLSSAPAIAVDVVKMLGESGLALEKKDNFNEKREQVHFIELSPEEKANLIKKDSRYGRIIC
RCENITEGEIVDSINRTLGARTIDGVKRRCRPGCGRCQGGFCGPRVQEIISRETGMNIEEVLLDKNGSYIISGKTK

Specific function: Unknown

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI13376331, Length=264, Percent_Identity=29.1666666666667, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI87082148, Length=247, Percent_Identity=28.3400809716599, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788574, Length=479, Percent_Identity=22.3382045929019, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565764, Length=286, Percent_Identity=29.3706293706294, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24585081, Length=278, Percent_Identity=30.5755395683453, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.1.99.5

Molecular weight: Translated: 52238; Mature: 52238

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYDVAIIGSGVIGGAIFRELTKYNLKVVELEKENDVAMGASKANSAIVHSGYDPEPGTL
CEEEEEEECCCHHHHHHHHHHHHCCEEEEEEECCCCEEECCCCCCCEEEECCCCCCCCEE
MAKYNVEGNKMFDKLCKDLSVPFKRNGSLIIGFDEDDQKELEVLYNRGIKNGVEGVKLLS
EEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHEEEC
AEEVLEMEPNLNKDVKGALFCPTGGIVGAYEFTIALSENAIDNGGELRLNSKVVGIEKDE
HHHHHHCCCCCCCCCCCEEECCCCCEEEEEEEEEEEECCCCCCCCEEEECCEEEEEECCC
NFKIKLENGDVVEARFVVNAAGIYADKIHNMVCEEDFKITPRKGEYYVLDKSQGRLFEKT
CEEEEECCCCEEEEEEEEEECHHHHHHHHHHHCCCCCEECCCCCCEEEEECCCCCHHHHH
IFQCPTKLGKGVLVTPTVHGNLLVGPDAIDTCDKDSVSTEYDGLAKVREVSLKTTNKVNF
HHHCHHHHCCCEEEEEEECCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCH
RENIRNFAGLRAIADKPDFIIGEAKDVKGFFDVAGIKSPGLSSAPAIAVDVVKMLGESGL
HHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCC
ALEKKDNFNEKREQVHFIELSPEEKANLIKKDSRYGRIICRCENITEGEIVDSINRTLGA
EECCCCCCCCHHCEEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCC
RTIDGVKRRCRPGCGRCQGGFCGPRVQEIISRETGMNIEEVLLDKNGSYIISGKTK
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCCCCEEEECCCC
>Mature Secondary Structure
MIYDVAIIGSGVIGGAIFRELTKYNLKVVELEKENDVAMGASKANSAIVHSGYDPEPGTL
CEEEEEEECCCHHHHHHHHHHHHCCEEEEEEECCCCEEECCCCCCCEEEECCCCCCCCEE
MAKYNVEGNKMFDKLCKDLSVPFKRNGSLIIGFDEDDQKELEVLYNRGIKNGVEGVKLLS
EEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHEEEC
AEEVLEMEPNLNKDVKGALFCPTGGIVGAYEFTIALSENAIDNGGELRLNSKVVGIEKDE
HHHHHHCCCCCCCCCCCEEECCCCCEEEEEEEEEEEECCCCCCCCEEEECCEEEEEECCC
NFKIKLENGDVVEARFVVNAAGIYADKIHNMVCEEDFKITPRKGEYYVLDKSQGRLFEKT
CEEEEECCCCEEEEEEEEEECHHHHHHHHHHHCCCCCEECCCCCCEEEEECCCCCHHHHH
IFQCPTKLGKGVLVTPTVHGNLLVGPDAIDTCDKDSVSTEYDGLAKVREVSLKTTNKVNF
HHHCHHHHCCCEEEEEEECCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCH
RENIRNFAGLRAIADKPDFIIGEAKDVKGFFDVAGIKSPGLSSAPAIAVDVVKMLGESGL
HHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCC
ALEKKDNFNEKREQVHFIELSPEEKANLIKKDSRYGRIICRCENITEGEIVDSINRTLGA
EECCCCCCCCHHCEEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCC
RTIDGVKRRCRPGCGRCQGGFCGPRVQEIISRETGMNIEEVLLDKNGSYIISGKTK
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sn-glycerol 3-phosphate; acceptor

Specific reaction: sn-glycerol 3-phosphate + acceptor = glycerone phosphate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]