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The map label for this gene is asnC

Identifier: 18311482

GI number: 18311482

Start: 2862925

End: 2864322

Strand: Direct

Name: asnC

Synonym: CPE2500

Alternate gene names: 18311482

Gene position: 2862925-2864322 (Clockwise)

Preceding gene: 18311480

Following gene: 18311486

Centisome position: 94.44

GC content: 33.4

Gene sequence:

>1398_bases
ATGAAAGATGTAGTTTTAGTAAAAAGTCTTTACAGAAACACTAGTGAATATAGTGATAAGAAAGTAAAAATCTCAGGTTG
GATAAGAACTTTAAGAGCATCAAATGCTTTTGGATTTATAGAAGTTAACGATGGTTCATTCTTTAAAAACGTTCAAGTAG
TTTTTGATAGCGCTAAGATATCAAACTACAAAGAAATTTCTAAATTACCTATAAGTTCATCAATATCAGTTATAGGAACT
TTAGTTGAGACTCCAGATTCAAAACAACCATTTGAAATTCAAGCAGAAGAAATAATAGTAGAAGGAATGTCAGATTCAGA
TTATCCTCTACAAAAGAAAAGACATACTTTTGAGTACTTAAGAACAATAGCTCACTTAAGACCAAGAAGTAATGCTTTCT
CAGCTACATTCAGAGTAAGAAGTGTTGCAGCTTACGCTATCCATAAATTCTTCCAAGATCAAGGATTTGTTTACACTCAT
ACTCCAATATTAACTGGTTCAGACTGTGAAGGTGCTGGAGAAATGTTTAGAGTAACAACTTTAGACATGATGGCTCCTCC
TATAGCAGAAGAAGGTGGAATTGACTTCTCACAAGATTTCTTTGGAAAAGAAACTAACCTTACAGTTTCAGGACAATTAA
ACGCTGAATGTTTTGCTTTAGCATTTAGAAATATCTATACATTTGGTCCTACATTTAGAGCTGAAAACTCAAACACAGTA
AAGCATGCTGCTGAGTTCTGGATGATAGAACCTGAAATGGCTTTTGCTGATTTAATAGATGACATGGAAGTTGCTGAAAA
CATGTTAAAATACGTTATAAAATACGTTATGGATGAATGTCCAGAAGAAATAGCTTTCTTCAACCAATTTGTTGATAAAG
GCTTATTAGAGAGATTAAACCATGTTGTAAACTCAGAATTCGGAAAAGTTACTTATACTGAAGCTGTTAAATTACTTCAA
GAATCAGGTAAAGAGTTCGAATATCCTGTTGAGTGGGGAATAGACCTTCAAACTGAACATGAAAGATATTTAACAGAGCA
AATATTCAAAAAACCTGTATTTGTAACTGACTATCCAAAGGATATTAAAGCGTTCTACATGAGATTAAATGAAGACGGAA
AAACAGTTGCTGCTATGGACTGCTTAGTTCCTGGAATAGGAGAAATCATAGGTGGTAGCCAAAGAGAAGAAAGACTTGAT
GTCTTAAAAGCTAGAATGGCTGAATTAAACTTAAATGAAGAAGATTACTGGTGGTATTTAGAACTTAGAAAATACGGTGA
AACTGTTCACTCTGGATTTGGTCTAGGTTTTGAAAGATTAATCATGTACATTACTGGAATGGCTAACATAAGAGACGTAA
TACCATTCCCAAGAACTACTGGTACTGCAGAATTCTAA

Upstream 100 bases:

>100_bases
TGGGTGGTACCGCGAATAATGCCATTCGTCCCATTAATTATGTGGATGAAGGGCTTTTTTATTTGGAATAAAACTTAATT
AGGAAAGAGAGGAAATAATA

Downstream 100 bases:

>100_bases
AATGGTCTGTATCAAAATATAACAAATAAAACTTACAAACATATTCTGAGAATTACTAGATTTCGCTAAGAATTTATAAT
TATTACTCCGAAGATATTAC

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MKDVVLVKSLYRNTSEYSDKKVKISGWIRTLRASNAFGFIEVNDGSFFKNVQVVFDSAKISNYKEISKLPISSSISVIGT
LVETPDSKQPFEIQAEEIIVEGMSDSDYPLQKKRHTFEYLRTIAHLRPRSNAFSATFRVRSVAAYAIHKFFQDQGFVYTH
TPILTGSDCEGAGEMFRVTTLDMMAPPIAEEGGIDFSQDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTV
KHAAEFWMIEPEMAFADLIDDMEVAENMLKYVIKYVMDECPEEIAFFNQFVDKGLLERLNHVVNSEFGKVTYTEAVKLLQ
ESGKEFEYPVEWGIDLQTEHERYLTEQIFKKPVFVTDYPKDIKAFYMRLNEDGKTVAAMDCLVPGIGEIIGGSQREERLD
VLKARMAELNLNEEDYWWYLELRKYGETVHSGFGLGFERLIMYITGMANIRDVIPFPRTTGTAEF

Sequences:

>Translated_465_residues
MKDVVLVKSLYRNTSEYSDKKVKISGWIRTLRASNAFGFIEVNDGSFFKNVQVVFDSAKISNYKEISKLPISSSISVIGT
LVETPDSKQPFEIQAEEIIVEGMSDSDYPLQKKRHTFEYLRTIAHLRPRSNAFSATFRVRSVAAYAIHKFFQDQGFVYTH
TPILTGSDCEGAGEMFRVTTLDMMAPPIAEEGGIDFSQDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTV
KHAAEFWMIEPEMAFADLIDDMEVAENMLKYVIKYVMDECPEEIAFFNQFVDKGLLERLNHVVNSEFGKVTYTEAVKLLQ
ESGKEFEYPVEWGIDLQTEHERYLTEQIFKKPVFVTDYPKDIKAFYMRLNEDGKTVAAMDCLVPGIGEIIGGSQREERLD
VLKARMAELNLNEEDYWWYLELRKYGETVHSGFGLGFERLIMYITGMANIRDVIPFPRTTGTAEF
>Mature_465_residues
MKDVVLVKSLYRNTSEYSDKKVKISGWIRTLRASNAFGFIEVNDGSFFKNVQVVFDSAKISNYKEISKLPISSSISVIGT
LVETPDSKQPFEIQAEEIIVEGMSDSDYPLQKKRHTFEYLRTIAHLRPRSNAFSATFRVRSVAAYAIHKFFQDQGFVYTH
TPILTGSDCEGAGEMFRVTTLDMMAPPIAEEGGIDFSQDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTV
KHAAEFWMIEPEMAFADLIDDMEVAENMLKYVIKYVMDECPEEIAFFNQFVDKGLLERLNHVVNSEFGKVTYTEAVKLLQ
ESGKEFEYPVEWGIDLQTEHERYLTEQIFKKPVFVTDYPKDIKAFYMRLNEDGKTVAAMDCLVPGIGEIIGGSQREERLD
VLKARMAELNLNEEDYWWYLELRKYGETVHSGFGLGFERLIMYITGMANIRDVIPFPRTTGTAEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=446, Percent_Identity=45.5156950672646, Blast_Score=401, Evalue=1e-112,
Organism=Homo sapiens, GI4758762, Length=454, Percent_Identity=27.3127753303965, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI45439306, Length=501, Percent_Identity=25.5489021956088, Blast_Score=112, Evalue=7e-25,
Organism=Escherichia coli, GI1787161, Length=451, Percent_Identity=58.0931263858093, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1790571, Length=465, Percent_Identity=24.7311827956989, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788173, Length=109, Percent_Identity=36.697247706422, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17556372, Length=442, Percent_Identity=31.447963800905, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71984122, Length=462, Percent_Identity=28.1385281385281, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17551876, Length=485, Percent_Identity=26.3917525773196, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319872, Length=484, Percent_Identity=37.603305785124, Blast_Score=320, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6321807, Length=459, Percent_Identity=27.0152505446623, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6323011, Length=342, Percent_Identity=28.9473684210526, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI19922416, Length=454, Percent_Identity=35.6828193832599, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI19921528, Length=468, Percent_Identity=26.9230769230769, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI17136276, Length=468, Percent_Identity=24.7863247863248, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_CLOP1 (Q0TMF3)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_697187.1
- ProteinModelPortal:   Q0TMF3
- SMR:   Q0TMF3
- STRING:   Q0TMF3
- GeneID:   4202179
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2823
- TIGR:   CPF_2823
- eggNOG:   NOG146472
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- BioCyc:   CPER195103:CPF_2823-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 53169; Mature: 53169

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVVLVKSLYRNTSEYSDKKVKISGWIRTLRASNAFGFIEVNDGSFFKNVQVVFDSAKI
CCCHHHHHHHHCCCHHCCCCEEEHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECHHH
SNYKEISKLPISSSISVIGTLVETPDSKQPFEIQAEEIIVEGMSDSDYPLQKKRHTFEYL
CCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEHHHHEEECCCCCCCCHHHHHHHHHHH
RTIAHLRPRSNAFSATFRVRSVAAYAIHKFFQDQGFVYTHTPILTGSDCEGAGEMFRVTT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCCCCEEEEEE
LDMMAPPIAEEGGIDFSQDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTV
HHHHCCCCCCCCCCCCCHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEECCCCCHH
KHAAEFWMIEPEMAFADLIDDMEVAENMLKYVIKYVMDECPEEIAFFNQFVDKGLLERLN
HHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
HVVNSEFGKVTYTEAVKLLQESGKEFEYPVEWGIDLQTEHERYLTEQIFKKPVFVTDYPK
HHHCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCH
DIKAFYMRLNEDGKTVAAMDCLVPGIGEIIGGSQREERLDVLKARMAELNLNEEDYWWYL
HHHHHHHHCCCCCCEEEHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
ELRKYGETVHSGFGLGFERLIMYITGMANIRDVIPFPRTTGTAEF
EHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKDVVLVKSLYRNTSEYSDKKVKISGWIRTLRASNAFGFIEVNDGSFFKNVQVVFDSAKI
CCCHHHHHHHHCCCHHCCCCEEEHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECHHH
SNYKEISKLPISSSISVIGTLVETPDSKQPFEIQAEEIIVEGMSDSDYPLQKKRHTFEYL
CCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEHHHHEEECCCCCCCCHHHHHHHHHHH
RTIAHLRPRSNAFSATFRVRSVAAYAIHKFFQDQGFVYTHTPILTGSDCEGAGEMFRVTT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCCCCEEEEEE
LDMMAPPIAEEGGIDFSQDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTV
HHHHCCCCCCCCCCCCCHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEECCCCCHH
KHAAEFWMIEPEMAFADLIDDMEVAENMLKYVIKYVMDECPEEIAFFNQFVDKGLLERLN
HHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
HVVNSEFGKVTYTEAVKLLQESGKEFEYPVEWGIDLQTEHERYLTEQIFKKPVFVTDYPK
HHHCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCH
DIKAFYMRLNEDGKTVAAMDCLVPGIGEIIGGSQREERLDVLKARMAELNLNEEDYWWYL
HHHHHHHHCCCCCCEEEHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
ELRKYGETVHSGFGLGFERLIMYITGMANIRDVIPFPRTTGTAEF
EHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA