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The map label for this gene is yacO [H]

Identifier: 18311406

GI number: 18311406

Start: 2772002

End: 2772871

Strand: Reverse

Name: yacO [H]

Synonym: CPE2424

Alternate gene names: 18311406

Gene position: 2772871-2772002 (Counterclockwise)

Preceding gene: 18311407

Following gene: 18311405

Centisome position: 91.47

GC content: 29.54

Gene sequence:

>870_bases
ATGACAAAGTCAGAAAATAAATATAAACAATTAACTCGTAAGCAAAAGTATGCTTTAGAAAGAGAACAAAGAGCAAGAGA
AGAAAAATATGCTAGAAATACTAGAACTTTTACTGAGGAAGAAGTTAAAGTAAGAGAAGATTTAGTAGAAGGAAGAAACG
CTGTTATAGAATTATTAAAGTCAGATAAGACTATAGAGCAAATATTTATAGCTAATGGAAAAATGGAAGGTTCAATAAAC
AAAATTTTAGGATTAGCTAAAGAAAAGAAAATAGTTGTAAAAGAAGTTGATAGAAAGAAACTTGACTTAATGAGCGAAAC
TAAAGCTCACCAAGGAGTAATAGCACAAATAACTCCTTTTAAATATAGTACTGTTGAAGATATATTAGATTTAGCTAAAA
GTAAAAATGAAGATCCATTCATAGTTATTTTAGATGAATTAGAGGATCCTCATAACTTAGGATCAATAGTAAGAACAGCA
GAATTATGTGGTGCACATGGTATCATAATTCCAAAGAGAAGAAATGTTGGAGTAACTGGAACTGTTTATAAAGCTTCTGT
AGGAGCTATTGAACATATGAAAATTGCAAAAGTTACTAATATAAATAATGCTATTGAAGAATTAAAGGCTAACAATGTAT
GGATATATGGAGCTGATATAGCTGGAGAAGAATATAGTTATGAAACAAACTTCAAAGGTGCTTGTGGAATAATAATCGGT
AGTGAAGGTAGAGGAATGTCAAACTTAACTAAGAAGAAGTGTGACAAGTTAGTTAAAATTCCAATGGTTGGAAAAATAAA
TTCTTTAAATGCCTCAGTTGCAGGTGGTATAATGATGTATGAGGTATTAAAATCAAGAATAATAAAGTAG

Upstream 100 bases:

>100_bases
GTAGCAGGTCCATGTCCTGAAGGAAAAATGTGTTGTGGAAAGCTTAAAGAGATGAGAACATTATATCTTGGAAAATAGGA
ATTTTTAAGGAGAGAACAAA

Downstream 100 bases:

>100_bases
AAAAAGAGTGATGAGATGAGAGTTATATTTATAGATGGTTATAATGTTATAAATAGTTGGCCTAATCTAAAAAAGTCAAA
AAATTATAGCTATGATATAG

Product: RNA methyltransferase, TrmH family, group 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTKSENKYKQLTRKQKYALEREQRAREEKYARNTRTFTEEEVKVREDLVEGRNAVIELLKSDKTIEQIFIANGKMEGSIN
KILGLAKEKKIVVKEVDRKKLDLMSETKAHQGVIAQITPFKYSTVEDILDLAKSKNEDPFIVILDELEDPHNLGSIVRTA
ELCGAHGIIIPKRRNVGVTGTVYKASVGAIEHMKIAKVTNINNAIEELKANNVWIYGADIAGEEYSYETNFKGACGIIIG
SEGRGMSNLTKKKCDKLVKIPMVGKINSLNASVAGGIMMYEVLKSRIIK

Sequences:

>Translated_289_residues
MTKSENKYKQLTRKQKYALEREQRAREEKYARNTRTFTEEEVKVREDLVEGRNAVIELLKSDKTIEQIFIANGKMEGSIN
KILGLAKEKKIVVKEVDRKKLDLMSETKAHQGVIAQITPFKYSTVEDILDLAKSKNEDPFIVILDELEDPHNLGSIVRTA
ELCGAHGIIIPKRRNVGVTGTVYKASVGAIEHMKIAKVTNINNAIEELKANNVWIYGADIAGEEYSYETNFKGACGIIIG
SEGRGMSNLTKKKCDKLVKIPMVGKINSLNASVAGGIMMYEVLKSRIIK
>Mature_288_residues
TKSENKYKQLTRKQKYALEREQRAREEKYARNTRTFTEEEVKVREDLVEGRNAVIELLKSDKTIEQIFIANGKMEGSINK
ILGLAKEKKIVVKEVDRKKLDLMSETKAHQGVIAQITPFKYSTVEDILDLAKSKNEDPFIVILDELEDPHNLGSIVRTAE
LCGAHGIIIPKRRNVGVTGTVYKASVGAIEHMKIAKVTNINNAIEELKANNVWIYGADIAGEEYSYETNFKGACGIIIGS
EGRGMSNLTKKKCDKLVKIPMVGKINSLNASVAGGIMMYEVLKSRIIK

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=251, Percent_Identity=23.5059760956175, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI1790623, Length=241, Percent_Identity=33.6099585062241, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1790083, Length=173, Percent_Identity=24.2774566473988, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788935, Length=256, Percent_Identity=22.265625, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555908, Length=281, Percent_Identity=25.6227758007117, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324775, Length=292, Percent_Identity=22.9452054794521, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32360; Mature: 32229

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSENKYKQLTRKQKYALEREQRAREEKYARNTRTFTEEEVKVREDLVEGRNAVIELLK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SDKTIEQIFIANGKMEGSINKILGLAKEKKIVVKEVDRKKLDLMSETKAHQGVIAQITPF
CCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
KYSTVEDILDLAKSKNEDPFIVILDELEDPHNLGSIVRTAELCGAHGIIIPKRRNVGVTG
CHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCE
TVYKASVGAIEHMKIAKVTNINNAIEELKANNVWIYGADIAGEEYSYETNFKGACGIIIG
EEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEC
SEGRGMSNLTKKKCDKLVKIPMVGKINSLNASVAGGIMMYEVLKSRIIK
CCCCCHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKSENKYKQLTRKQKYALEREQRAREEKYARNTRTFTEEEVKVREDLVEGRNAVIELLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SDKTIEQIFIANGKMEGSINKILGLAKEKKIVVKEVDRKKLDLMSETKAHQGVIAQITPF
CCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
KYSTVEDILDLAKSKNEDPFIVILDELEDPHNLGSIVRTAELCGAHGIIIPKRRNVGVTG
CHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCE
TVYKASVGAIEHMKIAKVTNINNAIEELKANNVWIYGADIAGEEYSYETNFKGACGIIIG
EEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEC
SEGRGMSNLTKKKCDKLVKIPMVGKINSLNASVAGGIMMYEVLKSRIIK
CCCCCHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]