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The map label for this gene is atpA

Identifier: 18311171

GI number: 18311171

Start: 2510598

End: 2512106

Strand: Reverse

Name: atpA

Synonym: CPE2189

Alternate gene names: 18311171

Gene position: 2512106-2510598 (Counterclockwise)

Preceding gene: 18311172

Following gene: 18311170

Centisome position: 82.87

GC content: 33.53

Gene sequence:

>1509_bases
ATGCATATTAAACCAGAAGAAATAACTTCTATAATCAAGAATGAAATAAAAAACTATGAAAAAGAGTTAGAAACTGTTGA
TTCTGGTACTATCATACAGATAGGTGACGGAGTTGCCAGAGTTTACGGGTTAGAAGAATGTATGGAAGGTGAACTTCTTG
AATTCCCTAATCAAGTTTTCGGTATGGCTCTTAACTTAGAGCAGGATAACGTTGGTTGCGTTCTTTTAGGATCTGAAGAA
GGTATAAAAGAAGGAGACATCGTTAAAAGAACTGGAAAAATAGTTGAAGTACCAGTAGGAGAGGACTTAATAGGTAGAGT
TGTTAATTCATTAGGTCAACCTATAGACGGAAAAGGTCCTATTAAAAATGATGGATACAGAGCTATAGAAGTACCAGCAC
CAGGTATCTTAGAAAGAAGTTCTGTTAATGAGCCTCTACAAACAGGTATCAAAGCAATTGACTCAATGATACCAATAGGT
AGAGGACAAAGGGAGTTAATTATAGGAGATAGACAAACAGGTAAAACTGCTATAGCTATAGATACTATAATTAACCAAAA
AGGTAAAGATGTTATATGTATATATGTTGCTATTGGACAAAAACAATCAACAGTAGCTAACATAGTTAACACTTTAACTG
AAGAAGGAGCTATGGACTATTCAATAGTTGTAACTGCATCAGCATCAGAATCAGCTCCATTACAATACATTGCACCATAT
TCAGGATGTACAATGGGTGAATACTTCATGAATAAAGGTAAGCATGTATTAATAATATATGATGACTTAAGTAAGCACGC
AGTTGCTTATAGAACAATGTCACTATTAATTAGAAGACCACCAGGAAGAGAAGCTTACCCAGGGGATGTATTCTACATCC
ATTCAAGATTACTTGAAAGAGCTGCTAAGTTATCAAAAGAAAATGGTGGAGGCTCATTAACAGCACTTCCAATAATAGAA
ACATTAGCAGGAGACGTAACAGCATATATCCCAACTAACGTTATATCAATAACAGATGGACAGATATTCTTAGAAACTGA
GTTATTCAACGCAGGACAAAGACCAGCTGTTAACCCTGGTATATCAGTTTCAAGGGTTGGAGGTAACGCTCAAATAAAAG
CAATGAAACAAGTTTCTGGTACATTAAGACTAGAACTTGCTCAATATAGAGAGTTAGCATCATTTGCTCAATTTGGTTCA
GACCTTGATAAAGATACTCAAGCAAGACTTGAAAAAGGTAAGAGACTTATCGAGATCTTAAAACAAGATCAATATAAGCC
AATGGCAGTTGAAAAACAAATTATGATAATATACGCTGCAGTTAACAATTTCTTACTAGATATCAAAGTTTCAGATATTA
AGAGATTTGAAAAAGAATTCTTAGAATATATGGATACTCATCATAGAGAAATTGGTAAAGCTATATTAGATAAGAAAGTT
TTAGACGATGAATTAAAATCTGCTTTAGAAAGTGCTATAGTAGAATTTAAAAAAATATTCTTAATGTAA

Upstream 100 bases:

>100_bases
CTTTATGTCAGAGTTGGCGATGATGTTATAGATGGTACTGTTAAATCTAGACTTGACGATATGAAACAGATAATGCTTAA
GAGAGAATAGAGGTGAGTCT

Downstream 100 bases:

>100_bases
AATAAGAGCATAGCTTTTTAATTAAAGCTATGCCCACATTTTTAAGAATGGAGGTGGAGCTTAAATGGCAGGTGCAGGAC
TTTTAGAAATTAAAAGAAGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MHIKPEEITSIIKNEIKNYEKELETVDSGTIIQIGDGVARVYGLEECMEGELLEFPNQVFGMALNLEQDNVGCVLLGSEE
GIKEGDIVKRTGKIVEVPVGEDLIGRVVNSLGQPIDGKGPIKNDGYRAIEVPAPGILERSSVNEPLQTGIKAIDSMIPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGKDVICIYVAIGQKQSTVANIVNTLTEEGAMDYSIVVTASASESAPLQYIAPY
SGCTMGEYFMNKGKHVLIIYDDLSKHAVAYRTMSLLIRRPPGREAYPGDVFYIHSRLLERAAKLSKENGGGSLTALPIIE
TLAGDVTAYIPTNVISITDGQIFLETELFNAGQRPAVNPGISVSRVGGNAQIKAMKQVSGTLRLELAQYRELASFAQFGS
DLDKDTQARLEKGKRLIEILKQDQYKPMAVEKQIMIIYAAVNNFLLDIKVSDIKRFEKEFLEYMDTHHREIGKAILDKKV
LDDELKSALESAIVEFKKIFLM

Sequences:

>Translated_502_residues
MHIKPEEITSIIKNEIKNYEKELETVDSGTIIQIGDGVARVYGLEECMEGELLEFPNQVFGMALNLEQDNVGCVLLGSEE
GIKEGDIVKRTGKIVEVPVGEDLIGRVVNSLGQPIDGKGPIKNDGYRAIEVPAPGILERSSVNEPLQTGIKAIDSMIPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGKDVICIYVAIGQKQSTVANIVNTLTEEGAMDYSIVVTASASESAPLQYIAPY
SGCTMGEYFMNKGKHVLIIYDDLSKHAVAYRTMSLLIRRPPGREAYPGDVFYIHSRLLERAAKLSKENGGGSLTALPIIE
TLAGDVTAYIPTNVISITDGQIFLETELFNAGQRPAVNPGISVSRVGGNAQIKAMKQVSGTLRLELAQYRELASFAQFGS
DLDKDTQARLEKGKRLIEILKQDQYKPMAVEKQIMIIYAAVNNFLLDIKVSDIKRFEKEFLEYMDTHHREIGKAILDKKV
LDDELKSALESAIVEFKKIFLM
>Mature_502_residues
MHIKPEEITSIIKNEIKNYEKELETVDSGTIIQIGDGVARVYGLEECMEGELLEFPNQVFGMALNLEQDNVGCVLLGSEE
GIKEGDIVKRTGKIVEVPVGEDLIGRVVNSLGQPIDGKGPIKNDGYRAIEVPAPGILERSSVNEPLQTGIKAIDSMIPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGKDVICIYVAIGQKQSTVANIVNTLTEEGAMDYSIVVTASASESAPLQYIAPY
SGCTMGEYFMNKGKHVLIIYDDLSKHAVAYRTMSLLIRRPPGREAYPGDVFYIHSRLLERAAKLSKENGGGSLTALPIIE
TLAGDVTAYIPTNVISITDGQIFLETELFNAGQRPAVNPGISVSRVGGNAQIKAMKQVSGTLRLELAQYRELASFAQFGS
DLDKDTQARLEKGKRLIEILKQDQYKPMAVEKQIMIIYAAVNNFLLDIKVSDIKRFEKEFLEYMDTHHREIGKAILDKKV
LDDELKSALESAIVEFKKIFLM

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=498, Percent_Identity=61.2449799196787, Blast_Score=624, Evalue=1e-179,
Organism=Homo sapiens, GI4757810, Length=498, Percent_Identity=61.2449799196787, Blast_Score=624, Evalue=1e-179,
Organism=Homo sapiens, GI19913428, Length=296, Percent_Identity=32.0945945945946, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI19913426, Length=389, Percent_Identity=27.7634961439589, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI32189394, Length=316, Percent_Identity=26.8987341772152, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI19913424, Length=247, Percent_Identity=26.7206477732794, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790172, Length=508, Percent_Identity=57.6771653543307, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1790170, Length=399, Percent_Identity=28.3208020050125, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788251, Length=339, Percent_Identity=29.7935103244838, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=61.1553784860558, Blast_Score=632, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=61.1553784860558, Blast_Score=630, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=56.7729083665339, Blast_Score=569, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI17570191, Length=296, Percent_Identity=30.0675675675676, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=319, Percent_Identity=26.9592476489028, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=291, Percent_Identity=29.553264604811, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=66, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565854, Length=253, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71988068, Length=74, Percent_Identity=39.1891891891892, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=505, Percent_Identity=59.6039603960396, Blast_Score=623, Evalue=1e-179,
Organism=Saccharomyces cerevisiae, GI6319603, Length=297, Percent_Identity=30.976430976431, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322581, Length=383, Percent_Identity=26.8929503916449, Blast_Score=116, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=60.7920792079208, Blast_Score=625, Evalue=1e-179,
Organism=Drosophila melanogaster, GI281361666, Length=294, Percent_Identity=30.6122448979592, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646341, Length=294, Percent_Identity=30.6122448979592, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136796, Length=294, Percent_Identity=30.6122448979592, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638766, Length=319, Percent_Identity=27.5862068965517, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28574560, Length=379, Percent_Identity=27.9683377308707, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24583988, Length=251, Percent_Identity=26.6932270916335, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583986, Length=251, Percent_Identity=26.6932270916335, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583984, Length=251, Percent_Identity=26.6932270916335, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583992, Length=254, Percent_Identity=26.3779527559055, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129479, Length=233, Percent_Identity=27.0386266094421, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_CLOP1 (Q0TNC2)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696868.1
- ProteinModelPortal:   Q0TNC2
- SMR:   Q0TNC2
- STRING:   Q0TNC2
- GeneID:   4203916
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2454
- TIGR:   CPF_2454
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- ProtClustDB:   PRK09281
- BioCyc:   CPER195103:CPF_2454-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55267; Mature: 55267

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIKPEEITSIIKNEIKNYEKELETVDSGTIIQIGDGVARVYGLEECMEGELLEFPNQVF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCHHHCCHHHH
GMALNLEQDNVGCVLLGSEEGIKEGDIVKRTGKIVEVPVGEDLIGRVVNSLGQPIDGKGP
CEEEEECCCCCCEEEECCCCCCCCCCHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
IKNDGYRAIEVPAPGILERSSVNEPLQTGIKAIDSMIPIGRGQRELIIGDRQTGKTAIAI
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEE
DTIINQKGKDVICIYVAIGQKQSTVANIVNTLTEEGAMDYSIVVTASASESAPLQYIAPY
EHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCC
SGCTMGEYFMNKGKHVLIIYDDLSKHAVAYRTMSLLIRRPPGREAYPGDVFYIHSRLLER
CCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
AAKLSKENGGGSLTALPIIETLAGDVTAYIPTNVISITDGQIFLETELFNAGQRPAVNPG
HHHHCCCCCCCCEEHHHHHHHHHCCEEEEECCCEEEEECCEEEEEEEHHCCCCCCCCCCC
ISVSRVGGNAQIKAMKQVSGTLRLELAQYRELASFAQFGSDLDKDTQARLEKGKRLIEIL
CEEEECCCCHHHHHHHHHCCHHEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
KQDQYKPMAVEKQIMIIYAAVNNFLLDIKVSDIKRFEKEFLEYMDTHHREIGKAILDKKV
HHCCCCCCEECCEEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDELKSALESAIVEFKKIFLM
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHIKPEEITSIIKNEIKNYEKELETVDSGTIIQIGDGVARVYGLEECMEGELLEFPNQVF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCHHHCCHHHH
GMALNLEQDNVGCVLLGSEEGIKEGDIVKRTGKIVEVPVGEDLIGRVVNSLGQPIDGKGP
CEEEEECCCCCCEEEECCCCCCCCCCHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
IKNDGYRAIEVPAPGILERSSVNEPLQTGIKAIDSMIPIGRGQRELIIGDRQTGKTAIAI
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEE
DTIINQKGKDVICIYVAIGQKQSTVANIVNTLTEEGAMDYSIVVTASASESAPLQYIAPY
EHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCC
SGCTMGEYFMNKGKHVLIIYDDLSKHAVAYRTMSLLIRRPPGREAYPGDVFYIHSRLLER
CCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
AAKLSKENGGGSLTALPIIETLAGDVTAYIPTNVISITDGQIFLETELFNAGQRPAVNPG
HHHHCCCCCCCCEEHHHHHHHHHCCEEEEECCCEEEEECCEEEEEEEHHCCCCCCCCCCC
ISVSRVGGNAQIKAMKQVSGTLRLELAQYRELASFAQFGSDLDKDTQARLEKGKRLIEIL
CEEEECCCCHHHHHHHHHCCHHEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
KQDQYKPMAVEKQIMIIYAAVNNFLLDIKVSDIKRFEKEFLEYMDTHHREIGKAILDKKV
HHCCCCCCEECCEEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDELKSALESAIVEFKKIFLM
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA