Click here to switch to the map view.

The map label for this gene is murA

Identifier: 18311166

GI number: 18311166

Start: 2505740

End: 2507005

Strand: Reverse

Name: murA

Synonym: CPE2184

Alternate gene names: 18311166

Gene position: 2507005-2505740 (Counterclockwise)

Preceding gene: 18311167

Following gene: 18311165

Centisome position: 82.7

GC content: 31.2

Gene sequence:

>1266_bases
ATGGATAAAATAGTAGTAAAAGGTGGAAAGAAATTAAAAGGAGAAGTAAATATAAATACAGCTAAGAATTCAGTTTTACC
AATAATCGCAGGAAGTATATTAGCTACTGATGGTGTACTAATAAATGAATTACCAATGTTACAAGATGTTTTTACAATTT
GTAATGTTATGGAGCAATTAGGATATGATTTGAAAATAGATAAGAAAGAAAATAAATTAATTGTACCACCATTAAATAAA
GATCCTTTAATTCCAAGTGAGGATTTAGTTAAAAAAATGAGAGCTTCATTTTTAATAATGGGGCCAATGATAGCTAAATA
TGGGGAGTTTAAATTAGCTAGGCCAGGTGGATGTAATATAGGTTCTAGGCCTATAGAATTACATTTGAAAGGGCTTAGAG
CATTAGGTGCTGAAGATAGTAATTGTGGCAATGGATTTGTATGTATAAAGGCAAAAAAATTAACAGGAAGTAAAATATAT
TTAGACTTTCCATCAGTTGGAGCAACAGAGAATATAATGATGGCAGCAACTATGGCTAAAGGGACTACGGTAATTGAAAA
TGCAGCTCAGGAGCCAGAAATAACTGATTTAATTAATTTTTTAAATTCTATGGGAGCTAAAATTTATATTGAAAAACCAG
GTAAAATAATAATAGAAGGTGTTGATTCATTAACTTCAACTGAGTACACTCCTATATATGATAGAATAGAAGCTGGAACA
TTTATGGTTGCAGCAGCAATAACAGGATCAGAAATAAAAATAAATGGAGTAAATAAAGATCATTGTTCAGCTATAATATC
TAAGTTAAAAGAAGCTGGAACAGAGTTTTTTGATATCCATAATGATGAAAATAGTATAATAGTAAAGGGTAATGAAGAAA
TAAAGCCAATTAATATAAAAACAATGCCTTATCCAGGATATCCTACTGATATGCAATCACAAATGATGAGTTTATTGAGC
ATAGCAAAAGGAAGCAGTATCATAACTGAAAGTGTTTTTGAGAATAGATTTATGAATGTAGATGAATTAAGACGTATGGG
TGCAAACATACAAGTAGAAGGAAGAACGGCTTTAATTGAAGGAGTAGATAACCTCACTGGATGTGAAGTTAAGGCAACTG
ATTTAAGGGCAGGAGCTGCTTTGATTTTAGCTGGACTTGTAGCAAAGGGAGAGACAATAGTTACTGATATATATCATATA
GATAGAGGTTATGTTGAAATAGAAAATAAGTTCAGGGCCTTAGGTGCTGACATAAGTAGAATATAA

Upstream 100 bases:

>100_bases
TTTAATTACTCCATTATGACATATGAGGAAGATAGGAAGTTGATTTTAGGAACTCCTATTATATTCACAACATATTAAAA
TAATTTTAATGGAGGATAAT

Downstream 100 bases:

>100_bases
GTCAACAGCAGTGCTGTTGACTTTTTTTACTTTAAATAATTTTATTATAAGTTCGAGTTTTAGAAAACTTAGCATATACA
TAAACTGTATTAATAAGTTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MDKIVVKGGKKLKGEVNINTAKNSVLPIIAGSILATDGVLINELPMLQDVFTICNVMEQLGYDLKIDKKENKLIVPPLNK
DPLIPSEDLVKKMRASFLIMGPMIAKYGEFKLARPGGCNIGSRPIELHLKGLRALGAEDSNCGNGFVCIKAKKLTGSKIY
LDFPSVGATENIMMAATMAKGTTVIENAAQEPEITDLINFLNSMGAKIYIEKPGKIIIEGVDSLTSTEYTPIYDRIEAGT
FMVAAAITGSEIKINGVNKDHCSAIISKLKEAGTEFFDIHNDENSIIVKGNEEIKPINIKTMPYPGYPTDMQSQMMSLLS
IAKGSSIITESVFENRFMNVDELRRMGANIQVEGRTALIEGVDNLTGCEVKATDLRAGAALILAGLVAKGETIVTDIYHI
DRGYVEIENKFRALGADISRI

Sequences:

>Translated_421_residues
MDKIVVKGGKKLKGEVNINTAKNSVLPIIAGSILATDGVLINELPMLQDVFTICNVMEQLGYDLKIDKKENKLIVPPLNK
DPLIPSEDLVKKMRASFLIMGPMIAKYGEFKLARPGGCNIGSRPIELHLKGLRALGAEDSNCGNGFVCIKAKKLTGSKIY
LDFPSVGATENIMMAATMAKGTTVIENAAQEPEITDLINFLNSMGAKIYIEKPGKIIIEGVDSLTSTEYTPIYDRIEAGT
FMVAAAITGSEIKINGVNKDHCSAIISKLKEAGTEFFDIHNDENSIIVKGNEEIKPINIKTMPYPGYPTDMQSQMMSLLS
IAKGSSIITESVFENRFMNVDELRRMGANIQVEGRTALIEGVDNLTGCEVKATDLRAGAALILAGLVAKGETIVTDIYHI
DRGYVEIENKFRALGADISRI
>Mature_421_residues
MDKIVVKGGKKLKGEVNINTAKNSVLPIIAGSILATDGVLINELPMLQDVFTICNVMEQLGYDLKIDKKENKLIVPPLNK
DPLIPSEDLVKKMRASFLIMGPMIAKYGEFKLARPGGCNIGSRPIELHLKGLRALGAEDSNCGNGFVCIKAKKLTGSKIY
LDFPSVGATENIMMAATMAKGTTVIENAAQEPEITDLINFLNSMGAKIYIEKPGKIIIEGVDSLTSTEYTPIYDRIEAGT
FMVAAAITGSEIKINGVNKDHCSAIISKLKEAGTEFFDIHNDENSIIVKGNEEIKPINIKTMPYPGYPTDMQSQMMSLLS
IAKGSSIITESVFENRFMNVDELRRMGANIQVEGRTALIEGVDNLTGCEVKATDLRAGAALILAGLVAKGETIVTDIYHI
DRGYVEIENKFRALGADISRI

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=428, Percent_Identity=45.7943925233645, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA1_CLOPE (Q8XID7)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_563100.1
- ProteinModelPortal:   Q8XID7
- SMR:   Q8XID7
- GeneID:   990508
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE2184
- NMPDR:   fig|195102.1.peg.2247
- HOGENOM:   HBG482701
- OMA:   NRFMHLE
- PhylomeDB:   Q8XID7
- ProtClustDB:   PRK09369
- BioCyc:   CPER195102:CPE2184-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45720; Mature: 45720

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVVKGGKKLKGEVNINTAKNSVLPIIAGSILATDGVLINELPMLQDVFTICNVMEQL
CCCEEEECCCEEEEEEEEECCCCCEEHEEECHHHHCCCEEECCCHHHHHHHHHHHHHHHC
GYDLKIDKKENKLIVPPLNKDPLIPSEDLVKKMRASFLIMGPMIAKYGEFKLARPGGCNI
CCCEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHEEEECHHHHHCCCEEEECCCCCCC
GSRPIELHLKGLRALGAEDSNCGNGFVCIKAKKLTGSKIYLDFPSVGATENIMMAATMAK
CCCCEEEEEEHHHHCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCEEEEEECCC
GTTVIENAAQEPEITDLINFLNSMGAKIYIEKPGKIIIEGVDSLTSTEYTPIYDRIEAGT
CCHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHCCCE
FMVAAAITGSEIKINGVNKDHCSAIISKLKEAGTEFFDIHNDENSIIVKGNEEIKPINIK
EEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCEEEEE
TMPYPGYPTDMQSQMMSLLSIAKGSSIITESVFENRFMNVDELRRMGANIQVEGRTALIE
ECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCEEECCCEEEEE
GVDNLTGCEVKATDLRAGAALILAGLVAKGETIVTDIYHIDRGYVEIENKFRALGADISR
CCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEEEECCCCEEEECHHHHHHCCHHHC
I
C
>Mature Secondary Structure
MDKIVVKGGKKLKGEVNINTAKNSVLPIIAGSILATDGVLINELPMLQDVFTICNVMEQL
CCCEEEECCCEEEEEEEEECCCCCEEHEEECHHHHCCCEEECCCHHHHHHHHHHHHHHHC
GYDLKIDKKENKLIVPPLNKDPLIPSEDLVKKMRASFLIMGPMIAKYGEFKLARPGGCNI
CCCEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHEEEECHHHHHCCCEEEECCCCCCC
GSRPIELHLKGLRALGAEDSNCGNGFVCIKAKKLTGSKIYLDFPSVGATENIMMAATMAK
CCCCEEEEEEHHHHCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCEEEEEECCC
GTTVIENAAQEPEITDLINFLNSMGAKIYIEKPGKIIIEGVDSLTSTEYTPIYDRIEAGT
CCHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHCCCE
FMVAAAITGSEIKINGVNKDHCSAIISKLKEAGTEFFDIHNDENSIIVKGNEEIKPINIK
EEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCEEEEE
TMPYPGYPTDMQSQMMSLLSIAKGSSIITESVFENRFMNVDELRRMGANIQVEGRTALIE
ECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCEEECCCEEEEE
GVDNLTGCEVKATDLRAGAALILAGLVAKGETIVTDIYHIDRGYVEIENKFRALGADISR
CCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEEEECCCCEEEECHHHHHHCCHHHC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842