Click here to switch to the map view.

The map label for this gene is uvsE

Identifier: 18311054

GI number: 18311054

Start: 2374217

End: 2375455

Strand: Direct

Name: uvsE

Synonym: CPE2072

Alternate gene names: 18311054

Gene position: 2374217-2375455 (Clockwise)

Preceding gene: 18311046

Following gene: 18311055

Centisome position: 78.32

GC content: 24.94

Gene sequence:

>1239_bases
ATGAAAATAGGATATGCTTGTACTCCAATAACTACAAATGCTAGAACAAATCGCAGAATATTACTAAAGGATTTTTCTAA
GGATAAATTCCTTTCTATTACAAAGCAAAACTTAGATGATTTACAAAAAATATTAGAATGGAATATTAAAAATAATATTT
ACTTATTTAGAATAGGCTCAGATATTATCCCCTTAGGTTCCCATGAAATAAATAATATAAGCTGGCAAAAAGAATTTAAA
GATAAATTAGAAACAATAGGAACTTTTATTAAGAATAATAAAATTAGAGTTTCTATGCATCCTGGTCAATATACAGTAAT
AAATACTCCTAAGGAGGATGTATTATACAAATCTATAAAGGATATTGAGTATCACTGTGAGTTTTTAGACTCCTTAAAGG
TAGATTATAAAAATAAAATAATACTTCATATAGGAGGGGTATATGGCGATAAAAAATTAGCAAAGGAAAACTTTTTAAAG
GGATTTAAAAAGCTTTCAGATTCTTCTAAAAAGCGATTAGTCATAGAAAATGATGAGAGAAATTTTTCTCTAGATGATGT
TTTAGATATTTCTAGTAAATTAAATATTCCTGTTATATTTGATAATTTACATAATATATGCTATGGGGATAATTCCTATA
GTTTAAAAGAAATTTACTCACTTGTTATTAAAACATGGAATAAAGAGTTAGATGGAAATATGAAAGTACATTATAGTGAG
CAGGACATTTTTAAAAAGAAAGGGTCTCACTCTCCTTCAATTTCTATAAATAGTTTTTTAGAATATTATGAAGAGATTAA
AGAATTTTCTCCTGACATAATGTTAGAGGTTAAGGATAAGGATATCTCTGCAATTAAGTGCATAAACTCCTTAAAAGAAA
TAAATAAAACATTAAACTCTAAAGCTTATAGGGAAGAGATAGAAAATTATAAATTACTTTTGCTTCAACATGATAAAGAC
TTTCAGAAAAAGCTTAACTCCTTTTCTAAAGATTTAATAGAATTTTATAATTATTTAGATAAATTATTACTATCTCCTAA
GGATATTATAGGATTTAAATACTCTTTAGAACTAGCTTTTAATATTTTAAAAGATCGCATAAGTAATAGGGAAAGTCTAT
ATTTTAAAAAGCTTATTAATGAAAAAGAATATGAAAAAGCTAAAGTTTATTTAACAAAGTTAGTAAAGAAAATAGAATTT
CCCCCTAAGGAATTATCTTATTATATTTCCCAGTCTTAA

Upstream 100 bases:

>100_bases
AAGTAATACTTAAAAGTTAATACGTTTCTAAAACTTTTTGTTTTATTTTTTATTTAAATGCAAAATATATAATTAATATT
TTGAAAAGGATTGATTATAT

Downstream 100 bases:

>100_bases
GCTTACTCTCCCTCTAAAATTGTCACAATTTATACATTAATAAAATATATTGGAATTAACAGTAAAATTTTGGAGGCAGA
AAAAGTGAGCTTTTTAAGTA

Product: putative UV damage endonuclease

Products: NA

Alternate protein names: UV-endonuclease; UVED

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKIGYACTPITTNARTNRRILLKDFSKDKFLSITKQNLDDLQKILEWNIKNNIYLFRIGSDIIPLGSHEINNISWQKEFK
DKLETIGTFIKNNKIRVSMHPGQYTVINTPKEDVLYKSIKDIEYHCEFLDSLKVDYKNKIILHIGGVYGDKKLAKENFLK
GFKKLSDSSKKRLVIENDERNFSLDDVLDISSKLNIPVIFDNLHNICYGDNSYSLKEIYSLVIKTWNKELDGNMKVHYSE
QDIFKKKGSHSPSISINSFLEYYEEIKEFSPDIMLEVKDKDISAIKCINSLKEINKTLNSKAYREEIENYKLLLLQHDKD
FQKKLNSFSKDLIEFYNYLDKLLLSPKDIIGFKYSLELAFNILKDRISNRESLYFKKLINEKEYEKAKVYLTKLVKKIEF
PPKELSYYISQS

Sequences:

>Translated_412_residues
MKIGYACTPITTNARTNRRILLKDFSKDKFLSITKQNLDDLQKILEWNIKNNIYLFRIGSDIIPLGSHEINNISWQKEFK
DKLETIGTFIKNNKIRVSMHPGQYTVINTPKEDVLYKSIKDIEYHCEFLDSLKVDYKNKIILHIGGVYGDKKLAKENFLK
GFKKLSDSSKKRLVIENDERNFSLDDVLDISSKLNIPVIFDNLHNICYGDNSYSLKEIYSLVIKTWNKELDGNMKVHYSE
QDIFKKKGSHSPSISINSFLEYYEEIKEFSPDIMLEVKDKDISAIKCINSLKEINKTLNSKAYREEIENYKLLLLQHDKD
FQKKLNSFSKDLIEFYNYLDKLLLSPKDIIGFKYSLELAFNILKDRISNRESLYFKKLINEKEYEKAKVYLTKLVKKIEF
PPKELSYYISQS
>Mature_412_residues
MKIGYACTPITTNARTNRRILLKDFSKDKFLSITKQNLDDLQKILEWNIKNNIYLFRIGSDIIPLGSHEINNISWQKEFK
DKLETIGTFIKNNKIRVSMHPGQYTVINTPKEDVLYKSIKDIEYHCEFLDSLKVDYKNKIILHIGGVYGDKKLAKENFLK
GFKKLSDSSKKRLVIENDERNFSLDDVLDISSKLNIPVIFDNLHNICYGDNSYSLKEIYSLVIKTWNKELDGNMKVHYSE
QDIFKKKGSHSPSISINSFLEYYEEIKEFSPDIMLEVKDKDISAIKCINSLKEINKTLNSKAYREEIENYKLLLLQHDKD
FQKKLNSFSKDLIEFYNYLDKLLLSPKDIIGFKYSLELAFNILKDRISNRESLYFKKLINEKEYEKAKVYLTKLVKKIEF
PPKELSYYISQS

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UVSE_CLOPE (Q8XIP3)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_562988.1
- ProteinModelPortal:   Q8XIP3
- SMR:   Q8XIP3
- GeneID:   990387
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE2072
- NMPDR:   fig|195102.1.peg.2135
- HOGENOM:   HBG704837
- OMA:   IMLEVKD
- BioCyc:   CPER195102:CPE2072-MONOMER
- HAMAP:   MF_00606
- InterPro:   IPR004601
- InterPro:   IPR013022
- TIGRFAMs:   TIGR00629

Pfam domain/function: PF03851 UvdE; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: NA

Molecular weight: Translated: 48463; Mature: 48463

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGYACTPITTNARTNRRILLKDFSKDKFLSITKQNLDDLQKILEWNIKNNIYLFRIGS
CCCCEEECCEECCCCCCCEEEEEECCCCHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECC
DIIPLGSHEINNISWQKEFKDKLETIGTFIKNNKIRVSMHPGQYTVINTPKEDVLYKSIK
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCHHHHHHHHHH
DIEYHCEFLDSLKVDYKNKIILHIGGVYGDKKLAKENFLKGFKKLSDSSKKRLVIENDER
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
NFSLDDVLDISSKLNIPVIFDNLHNICYGDNSYSLKEIYSLVIKTWNKELDGNMKVHYSE
CCCHHHHHHHHCCCCCEEEECCCCHHEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEECH
QDIFKKKGSHSPSISINSFLEYYEEIKEFSPDIMLEVKDKDISAIKCINSLKEINKTLNS
HHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
KAYREEIENYKLLLLQHDKDFQKKLNSFSKDLIEFYNYLDKLLLSPKDIIGFKYSLELAF
HHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEHHHHHHH
NILKDRISNRESLYFKKLINEKEYEKAKVYLTKLVKKIEFPPKELSYYISQS
HHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MKIGYACTPITTNARTNRRILLKDFSKDKFLSITKQNLDDLQKILEWNIKNNIYLFRIGS
CCCCEEECCEECCCCCCCEEEEEECCCCHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECC
DIIPLGSHEINNISWQKEFKDKLETIGTFIKNNKIRVSMHPGQYTVINTPKEDVLYKSIK
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCHHHHHHHHHH
DIEYHCEFLDSLKVDYKNKIILHIGGVYGDKKLAKENFLKGFKKLSDSSKKRLVIENDER
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
NFSLDDVLDISSKLNIPVIFDNLHNICYGDNSYSLKEIYSLVIKTWNKELDGNMKVHYSE
CCCHHHHHHHHCCCCCEEEECCCCHHEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEECH
QDIFKKKGSHSPSISINSFLEYYEEIKEFSPDIMLEVKDKDISAIKCINSLKEINKTLNS
HHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
KAYREEIENYKLLLLQHDKDFQKKLNSFSKDLIEFYNYLDKLLLSPKDIIGFKYSLELAF
HHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEHHHHHHH
NILKDRISNRESLYFKKLINEKEYEKAKVYLTKLVKKIEFPPKELSYYISQS
HHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842