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The map label for this gene is spoIIAB

Identifier: 18311031

GI number: 18311031

Start: 2340087

End: 2340509

Strand: Reverse

Name: spoIIAB

Synonym: CPE2049

Alternate gene names: 18311031

Gene position: 2340509-2340087 (Counterclockwise)

Preceding gene: 18311032

Following gene: 18311030

Centisome position: 77.21

GC content: 30.73

Gene sequence:

>423_bases
ATGGATAATAAAATGAGATTAGAGTTTTTGGCTAAATCTGAAAATGAAGGATTTGCAAGGGTGAGTGTATCAGCTTTTAT
TGCTCAATTAGATCCGACTATTGAAGAATTAACTGATATAAAGACTGCTGTTTCTGAGGCTGTAACAAATGCTATAATTC
ATGGATATGAATGTGATGAGAGCAAAGTGGTTATTATTGAGGCTAGTATTTGTGAAGATGAAATAAGTATAACTGTAGAA
GATAATGGTATAGGAATAGAAAATTTAGAAGAAGCAAGAGAACCCTTATATACATCTAAACCAGAATTAGAGAGATCAGG
TATGGGATTTACTGTTATGGAAACATTCATGGATTCTTTAGAAGTTTATAGTGAAAAGGATAAGGGTACAAAAATAATAA
TGAAGAAAAAAATGAATACATAG

Upstream 100 bases:

>100_bases
AGCATAAAAAGAGTTTTTGAGTTATCTGGAATATTTAAGATAATAAAGTATTACGAAAATTTGGATGAAGCTCTAAAAGT
GGGTTAATGGAGGGTTAGAT

Downstream 100 bases:

>100_bases
GCAGGTGAATAAAGTCTATGGATATAAGTAGTATTGAGAAAGATAATTTTAATTATGACAAAAATACAACTCTCATAGTC
ATGGCTAAAGAAGGAAATAA

Product: anti-sigma F factor

Products: NA

Alternate protein names: Stage II sporulation protein AB

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MDNKMRLEFLAKSENEGFARVSVSAFIAQLDPTIEELTDIKTAVSEAVTNAIIHGYECDESKVVIIEASICEDEISITVE
DNGIGIENLEEAREPLYTSKPELERSGMGFTVMETFMDSLEVYSEKDKGTKIIMKKKMNT

Sequences:

>Translated_140_residues
MDNKMRLEFLAKSENEGFARVSVSAFIAQLDPTIEELTDIKTAVSEAVTNAIIHGYECDESKVVIIEASICEDEISITVE
DNGIGIENLEEAREPLYTSKPELERSGMGFTVMETFMDSLEVYSEKDKGTKIIMKKKMNT
>Mature_140_residues
MDNKMRLEFLAKSENEGFARVSVSAFIAQLDPTIEELTDIKTAVSEAVTNAIIHGYECDESKVVIIEASICEDEISITVE
DNGIGIENLEEAREPLYTSKPELERSGMGFTVMETFMDSLEVYSEKDKGTKIIMKKKMNT

Specific function: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases si

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SP2AB_CLOP1 (Q0TNR1)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696729.1
- ProteinModelPortal:   Q0TNR1
- SMR:   Q0TNR1
- STRING:   Q0TNR1
- GeneID:   4203005
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2306
- TIGR:   CPF_2306
- eggNOG:   COG2172
- HOGENOM:   HBG425195
- OMA:   KSKALCN
- ProtClustDB:   PRK03660
- BioCyc:   CPER195103:CPF_2306-MONOMER
- HAMAP:   MF_00637
- InterPro:   IPR010194
- InterPro:   IPR003594
- Gene3D:   G3DSA:3.30.565.10
- SMART:   SM00387
- TIGRFAMs:   TIGR01925

Pfam domain/function: PF02518 HATPase_c; SSF55874 ATP_bd_ATPase

EC number: =2.7.11.1

Molecular weight: Translated: 15666; Mature: 15666

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKMRLEFLAKSENEGFARVSVSAFIAQLDPTIEELTDIKTAVSEAVTNAIIHGYECDE
CCCCEEEEEEECCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEECCC
SKVVIIEASICEDEISITVEDNGIGIENLEEAREPLYTSKPELERSGMGFTVMETFMDSL
CEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
EVYSEKDKGTKIIMKKKMNT
HHHCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MDNKMRLEFLAKSENEGFARVSVSAFIAQLDPTIEELTDIKTAVSEAVTNAIIHGYECDE
CCCCEEEEEEECCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEECCC
SKVVIIEASICEDEISITVEDNGIGIENLEEAREPLYTSKPELERSGMGFTVMETFMDSL
CEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
EVYSEKDKGTKIIMKKKMNT
HHHCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA