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The map label for this gene is msrR [H]

Identifier: 18310896

GI number: 18310896

Start: 2192466

End: 2193887

Strand: Direct

Name: msrR [H]

Synonym: CPE1914

Alternate gene names: 18310896

Gene position: 2192466-2193887 (Clockwise)

Preceding gene: 18310895

Following gene: 18310898

Centisome position: 72.32

GC content: 28.2

Gene sequence:

>1422_bases
ATGGATAAAAAGAAACACTTTAATTTTAGTAAAAAACAAAAAATAACTATATTTTCTTTATTAGCTATCCTTATATTAAT
CGCATCTGTAGTAGGCTTTTTTGTTTTTAGATTTTACAACCACTCCTACGAAGGAAATACGGATCCTGCTAAAGTTAATA
CTGTAGATGAAGATATTAAGTTTAAAGAGGTTCCAGGAATAACAAATATTCTTTTGCTTAGTAGCGATGCTAGACCTGGA
GAAGATGTATCTAGATCAGATTCTATAATGATCTTAACAATAGATAATATCAATAAAAAGTTAAAAGTAACTTCTTTAAT
GAGAGATATGTTAGTAAAAATAGATGGTCATGGAGAAGAAAAATTAAATCATGCCTTTGCTTATGGTGGTCCTATTAAAA
CAATTGAAACTATTCAAAATAATTTCGGAATAAAATTAAATAATTATGTAATTGTAGATTTTAGTGCTTTTGTTAAGGTT
ATAGATGCTATAAACGGAATTGAAGTAACAGTTAAAGATTATGAACTTGATGAACTTAATAAATATATTTTAGATGGTGG
CGGTTCTGAAGAAGATTTACTTCCTTCACCTGGAACTTATAATCTTAATGGTTATCAAGCCTTATCTTATGCTAGAATTA
GAAAAGTGGGTAATGGTGAATATGAAAGAACTGAAAGACAGAGAGCTGTTCTTCAAATCGCTTTAGAAAAAGTTAAAGAT
ATGTCAACAGTTAAACTTGTTTCCCTACTTAATGAATTATTCCCATATGTAAAAACTAATATTTCCTTAGGAAATGCTAT
GGATTATGGATTTACAGCCTTAAATGTAGGTAAAAAGTGTAACTTTGAAATAGAGCAATTTAGAGTTCCTCTAGATAGTA
TTTCAAAAGGTGGAATTATTAATAATAAGGGTTGGGTCTTTGTTATTGATAAGGTAGAAACATCAAAGGCTCTTCAAGAG
TTCATATTTAATGACAATAAAAATTATGAGCCTGATACTAGTAATTTTGACTCTATAATAGAACAATACTTTAATGACTA
TGATATTAAAGATGATACTACTCACCCAGATTATGAATATGTACCTAGTATAAATACTAATGGAAATTTTGAAAAACCTA
AAAATAATTCTGGCAATAGTAGTAATAATAATTCTAATAATAAAGTAGAAAAACCTTCTAACCAAGGAAATAGTGTAAAT
TCTTCTAATAAACCAAGTAGTGGAAGTACTTCTACTGGTAATAATTCTACAGAAAAACCTAATACTTCAGAAAAACCAAG
TATTCCTCAAGAAACTCCAACAGAAAAACCGTCTGAAAATAATGGTTCTAGTGGAAATGGAGAATCCTCTAACACGCAAT
CTAATAATGGAAATACTTCTTCTGAAAATAGTAATAATCAAAATAATACTGAAGGAAATTAA

Upstream 100 bases:

>100_bases
TTTAAATATGATGTTCTAAAATAAATATTATGTTATTATTAAATAATTAAGTTTTAGCTACTCATTAAAACGTTTAAACA
AATCATAAAAAGGAGTACTT

Downstream 100 bases:

>100_bases
TAAAGAGCTATATAGAACTAATAAATTAGATTCTATATAGCTTCTTCTTTGTTATTATAAATATAATATTACAGAGAAAA
AGTGACTTATGCTTCCTCCC

Product: PBP 5 synthesis repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MDKKKHFNFSKKQKITIFSLLAILILIASVVGFFVFRFYNHSYEGNTDPAKVNTVDEDIKFKEVPGITNILLLSSDARPG
EDVSRSDSIMILTIDNINKKLKVTSLMRDMLVKIDGHGEEKLNHAFAYGGPIKTIETIQNNFGIKLNNYVIVDFSAFVKV
IDAINGIEVTVKDYELDELNKYILDGGGSEEDLLPSPGTYNLNGYQALSYARIRKVGNGEYERTERQRAVLQIALEKVKD
MSTVKLVSLLNELFPYVKTNISLGNAMDYGFTALNVGKKCNFEIEQFRVPLDSISKGGIINNKGWVFVIDKVETSKALQE
FIFNDNKNYEPDTSNFDSIIEQYFNDYDIKDDTTHPDYEYVPSINTNGNFEKPKNNSGNSSNNNSNNKVEKPSNQGNSVN
SSNKPSSGSTSTGNNSTEKPNTSEKPSIPQETPTEKPSENNGSSGNGESSNTQSNNGNTSSENSNNQNNTEGN

Sequences:

>Translated_473_residues
MDKKKHFNFSKKQKITIFSLLAILILIASVVGFFVFRFYNHSYEGNTDPAKVNTVDEDIKFKEVPGITNILLLSSDARPG
EDVSRSDSIMILTIDNINKKLKVTSLMRDMLVKIDGHGEEKLNHAFAYGGPIKTIETIQNNFGIKLNNYVIVDFSAFVKV
IDAINGIEVTVKDYELDELNKYILDGGGSEEDLLPSPGTYNLNGYQALSYARIRKVGNGEYERTERQRAVLQIALEKVKD
MSTVKLVSLLNELFPYVKTNISLGNAMDYGFTALNVGKKCNFEIEQFRVPLDSISKGGIINNKGWVFVIDKVETSKALQE
FIFNDNKNYEPDTSNFDSIIEQYFNDYDIKDDTTHPDYEYVPSINTNGNFEKPKNNSGNSSNNNSNNKVEKPSNQGNSVN
SSNKPSSGSTSTGNNSTEKPNTSEKPSIPQETPTEKPSENNGSSGNGESSNTQSNNGNTSSENSNNQNNTEGN
>Mature_473_residues
MDKKKHFNFSKKQKITIFSLLAILILIASVVGFFVFRFYNHSYEGNTDPAKVNTVDEDIKFKEVPGITNILLLSSDARPG
EDVSRSDSIMILTIDNINKKLKVTSLMRDMLVKIDGHGEEKLNHAFAYGGPIKTIETIQNNFGIKLNNYVIVDFSAFVKV
IDAINGIEVTVKDYELDELNKYILDGGGSEEDLLPSPGTYNLNGYQALSYARIRKVGNGEYERTERQRAVLQIALEKVKD
MSTVKLVSLLNELFPYVKTNISLGNAMDYGFTALNVGKKCNFEIEQFRVPLDSISKGGIINNKGWVFVIDKVETSKALQE
FIFNDNKNYEPDTSNFDSIIEQYFNDYDIKDDTTHPDYEYVPSINTNGNFEKPKNNSGNSSNNNSNNKVEKPSNQGNSVN
SSNKPSSGSTSTGNNSTEKPNTSEKPSIPQETPTEKPSENNGSSGNGESSNTQSNNGNTSSENSNNQNNTEGN

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 52539; Mature: 52539

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKKHFNFSKKQKITIFSLLAILILIASVVGFFVFRFYNHSYEGNTDPAKVNTVDEDIK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCC
FKEVPGITNILLLSSDARPGEDVSRSDSIMILTIDNINKKLKVTSLMRDMLVKIDGHGEE
EECCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHEEECCCCHH
KLNHAFAYGGPIKTIETIQNNFGIKLNNYVIVDFSAFVKVIDAINGIEVTVKDYELDELN
HHHHHHHCCCCHHHHHHHHHCCCEEECCEEEEEHHHHHHHHHHCCCCEEEEECCCHHHHH
KYILDGGGSEEDLLPSPGTYNLNGYQALSYARIRKVGNGEYERTERQRAVLQIALEKVKD
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
MSTVKLVSLLNELFPYVKTNISLGNAMDYGFTALNVGKKCNFEIEQFRVPLDSISKGGII
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCHHHEECCHHHHCCCCEE
NNKGWVFVIDKVETSKALQEFIFNDNKNYEPDTSNFDSIIEQYFNDYDIKDDTTHPDYEY
CCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
VPSINTNGNFEKPKNNSGNSSNNNSNNKVEKPSNQGNSVNSSNKPSSGSTSTGNNSTEKP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NTSEKPSIPQETPTEKPSENNGSSGNGESSNTQSNNGNTSSENSNNQNNTEGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDKKKHFNFSKKQKITIFSLLAILILIASVVGFFVFRFYNHSYEGNTDPAKVNTVDEDIK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCC
FKEVPGITNILLLSSDARPGEDVSRSDSIMILTIDNINKKLKVTSLMRDMLVKIDGHGEE
EECCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHEEECCCCHH
KLNHAFAYGGPIKTIETIQNNFGIKLNNYVIVDFSAFVKVIDAINGIEVTVKDYELDELN
HHHHHHHCCCCHHHHHHHHHCCCEEECCEEEEEHHHHHHHHHHCCCCEEEEECCCHHHHH
KYILDGGGSEEDLLPSPGTYNLNGYQALSYARIRKVGNGEYERTERQRAVLQIALEKVKD
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
MSTVKLVSLLNELFPYVKTNISLGNAMDYGFTALNVGKKCNFEIEQFRVPLDSISKGGII
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCHHHEECCHHHHCCCCEE
NNKGWVFVIDKVETSKALQEFIFNDNKNYEPDTSNFDSIIEQYFNDYDIKDDTTHPDYEY
CCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
VPSINTNGNFEKPKNNSGNSSNNNSNNKVEKPSNQGNSVNSSNKPSSGSTSTGNNSTEKP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NTSEKPSIPQETPTEKPSENNGSSGNGESSNTQSNNGNTSSENSNNQNNTEGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]