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The map label for this gene is lldD [H]

Identifier: 18310860

GI number: 18310860

Start: 2153614

End: 2154636

Strand: Reverse

Name: lldD [H]

Synonym: CPE1878

Alternate gene names: 18310860

Gene position: 2154636-2153614 (Counterclockwise)

Preceding gene: 18310861

Following gene: 18310859

Centisome position: 71.08

GC content: 34.02

Gene sequence:

>1023_bases
ATGAATAAGGATATGAGAGATAAAGCTAGAGAACTTTATAATGGAAGTTGTAGAGTGTGTAAGATTTGTAATGGAGTAGC
ATGTGCAGGAGAAGTGCCTGGCATGGGAGGAAAAGGAACAGGAGATTCCTTTATAAGAAATGTAGCTGCCTTAGAGGAAA
TAAAACTTAATATGAGAACAATTCATGATGCTAAAAATCCTACTACAAATATTGAAATTTTCGGTAAGAATATGGAGTTA
CCACTTTTTGCAGCTCCTATAACAGGAACTATGTTAAATATGGGTGGAAAAGTTAGTGAAAGAGAATATATTGAGGGAGT
AGTTAAGGGATGCTTAGATTCAGGTATATATCCTATGGTAGGAGATACAGCAGTAGACTTATGTTTAGCTACTAATTTAG
AAGTAATAGAAGAATATAATGGACAAGGAATTATATTTATAAAACCTTGGAAAAATGAAGTTGTAATAGAAAAAATAAAA
ATGGCAGAAAAAGCAGGAGCCTTTGCTGTAGGCGTGGATATAGATGCAGCTGGACTTATAACTTTAGCTATGAATGGAAA
GCCAGTTGAACCTAAAAACTTAGAGGAAATAAAAGAACTAGTAAATTCAACAAAATTACCTTTTATACTTAAGGGAATAA
TGACGCCAGATGAGGCTGAATTAGCAGTAGAAGCAGGGGTAGATGCCATAGTAGTATCTAACCATGGAGGAAGAGTTTTA
GATCAAACTCCAGCTTCATGTGAAGTGTTACCAGAGATAGCAGCTAGGGTTAAAGGAAAAGTTAAAATTTTAGTTGATGG
TGGAGTAAGAACTGGAGTTGATATATTAAAAATGATAGCCTTAGGTGCTGATTGCGTTTTAATAGGAAGACCTTTTATAA
CAGCTACCTTTGCTCATGGAGCTAAAGGGGTAGAAGAATATGTGAATTCTTTAAAAGGTGAATTAAAATCAGCTATGGTA
TTAACAGGGTGTAACTCAATAGAAAATATAGATAATAGAGTTATTTACAAAGGAGAGAATTAA

Upstream 100 bases:

>100_bases
AATGGAGAGAAAAAAGAAGGAAATGGGGTAACTTGTGAACTTCTACTTCAAAATGGATTTAAAGTTAAGACAGAAAATGA
TTTTTAGGAGGAATGTATAA

Downstream 100 bases:

>100_bases
CTTATGAAAGTTTTTGCACATAGAGGATTTAGTTATAAATATCCAGAAAATACTTTGTTAGCATTTAAAGAGGCTTTAAA
ATTAGATATATATGGAATAG

Product: glycolate oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MNKDMRDKARELYNGSCRVCKICNGVACAGEVPGMGGKGTGDSFIRNVAALEEIKLNMRTIHDAKNPTTNIEIFGKNMEL
PLFAAPITGTMLNMGGKVSEREYIEGVVKGCLDSGIYPMVGDTAVDLCLATNLEVIEEYNGQGIIFIKPWKNEVVIEKIK
MAEKAGAFAVGVDIDAAGLITLAMNGKPVEPKNLEEIKELVNSTKLPFILKGIMTPDEAELAVEAGVDAIVVSNHGGRVL
DQTPASCEVLPEIAARVKGKVKILVDGGVRTGVDILKMIALGADCVLIGRPFITATFAHGAKGVEEYVNSLKGELKSAMV
LTGCNSIENIDNRVIYKGEN

Sequences:

>Translated_340_residues
MNKDMRDKARELYNGSCRVCKICNGVACAGEVPGMGGKGTGDSFIRNVAALEEIKLNMRTIHDAKNPTTNIEIFGKNMEL
PLFAAPITGTMLNMGGKVSEREYIEGVVKGCLDSGIYPMVGDTAVDLCLATNLEVIEEYNGQGIIFIKPWKNEVVIEKIK
MAEKAGAFAVGVDIDAAGLITLAMNGKPVEPKNLEEIKELVNSTKLPFILKGIMTPDEAELAVEAGVDAIVVSNHGGRVL
DQTPASCEVLPEIAARVKGKVKILVDGGVRTGVDILKMIALGADCVLIGRPFITATFAHGAKGVEEYVNSLKGELKSAMV
LTGCNSIENIDNRVIYKGEN
>Mature_340_residues
MNKDMRDKARELYNGSCRVCKICNGVACAGEVPGMGGKGTGDSFIRNVAALEEIKLNMRTIHDAKNPTTNIEIFGKNMEL
PLFAAPITGTMLNMGGKVSEREYIEGVVKGCLDSGIYPMVGDTAVDLCLATNLEVIEEYNGQGIIFIKPWKNEVVIEKIK
MAEKAGAFAVGVDIDAAGLITLAMNGKPVEPKNLEEIKELVNSTKLPFILKGIMTPDEAELAVEAGVDAIVVSNHGGRVL
DQTPASCEVLPEIAARVKGKVKILVDGGVRTGVDILKMIALGADCVLIGRPFITATFAHGAKGVEEYVNSLKGELKSAMV
LTGCNSIENIDNRVIYKGEN

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=346, Percent_Identity=28.9017341040462, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI54234014, Length=132, Percent_Identity=50, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI7705393, Length=132, Percent_Identity=50, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1790033, Length=150, Percent_Identity=45.3333333333333, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193208036, Length=145, Percent_Identity=43.448275862069, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6323587, Length=321, Percent_Identity=29.9065420560748, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281363140, Length=143, Percent_Identity=39.1608391608392, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI78707190, Length=143, Percent_Identity=39.1608391608392, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI78707188, Length=143, Percent_Identity=39.1608391608392, Blast_Score=114, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 36327; Mature: 36327

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKDMRDKARELYNGSCRVCKICNGVACAGEVPGMGGKGTGDSFIRNVAALEEIKLNMRT
CCCCHHHHHHHHHCCCCEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IHDAKNPTTNIEIFGKNMELPLFAAPITGTMLNMGGKVSEREYIEGVVKGCLDSGIYPMV
HHCCCCCCCEEEEEECCCCCCEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
GDTAVDLCLATNLEVIEEYNGQGIIFIKPWKNEVVIEKIKMAEKAGAFAVGVDIDAAGLI
CHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCEE
TLAMNGKPVEPKNLEEIKELVNSTKLPFILKGIMTPDEAELAVEAGVDAIVVSNHGGRVL
EEEECCCCCCCCCHHHHHHHHCCCCCCHHEECCCCCCHHHHHHHCCCCEEEEECCCCEEE
DQTPASCEVLPEIAARVKGKVKILVDGGVRTGVDILKMIALGADCVLIGRPFITATFAHG
CCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEECCCHHEEEHHHC
AKGVEEYVNSLKGELKSAMVLTGCNSIENIDNRVIYKGEN
HHHHHHHHHHHHHHHHHEEEEECCCCHHCCCCEEEEECCC
>Mature Secondary Structure
MNKDMRDKARELYNGSCRVCKICNGVACAGEVPGMGGKGTGDSFIRNVAALEEIKLNMRT
CCCCHHHHHHHHHCCCCEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IHDAKNPTTNIEIFGKNMELPLFAAPITGTMLNMGGKVSEREYIEGVVKGCLDSGIYPMV
HHCCCCCCCEEEEEECCCCCCEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
GDTAVDLCLATNLEVIEEYNGQGIIFIKPWKNEVVIEKIKMAEKAGAFAVGVDIDAAGLI
CHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCEE
TLAMNGKPVEPKNLEEIKELVNSTKLPFILKGIMTPDEAELAVEAGVDAIVVSNHGGRVL
EEEECCCCCCCCCHHHHHHHHCCCCCCHHEECCCCCCHHHHHHHCCCCEEEEECCCCEEE
DQTPASCEVLPEIAARVKGKVKILVDGGVRTGVDILKMIALGADCVLIGRPFITATFAHG
CCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEECCCHHEEEHHHC
AKGVEEYVNSLKGELKSAMVLTGCNSIENIDNRVIYKGEN
HHHHHHHHHHHHHHHHHEEEEECCCCHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA