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The map label for this gene is fchA [H]

Identifier: 18310850

GI number: 18310850

Start: 2139099

End: 2139734

Strand: Reverse

Name: fchA [H]

Synonym: CPE1868

Alternate gene names: 18310850

Gene position: 2139734-2139099 (Counterclockwise)

Preceding gene: 18310851

Following gene: 18310848

Centisome position: 70.58

GC content: 28.46

Gene sequence:

>636_bases
ATGAAAAACGAAAAGATTAAAGATTTTATAGAAGATTTAGGTTCAAGTTCATCAGCACCTGGTGGTGGGGCAGCAGCAGG
TATTGTTGGAGCAGTAGGAGTTGCATTAACATCAATGGTTTATAGCTTAACTGTTGGTAAAAAAGCTTACGAGGCATTAA
GTGAAGAAAATAAAAAGAAATTAGATGAAAATCTTGAAAATGCAAAAAAATCTTATAATGAAATGTTAGATTTCATGAAC
AAAGATGAGGAAGCTTTTACTGCATTAATGGATTGCTATAAGTTACCTAAGGAAACTTGTGAAGAGAAAAGCTTAAGAAG
TGAAAAAATATATGAATGTACTTTAGGGGCAATGATGGTTCCATTAGAATTAAGCAGAAAAGCCTTAAAGTTTTTTGATA
ATGTAAAATTTGCTTCTAAGTATGGAAATAAAAATTTAATTTCAGATGCTGTAGTAAGTGCTATAATGCTTAGTGCTTGT
ATAGATAGTTCCATAGTTAATGTAGAAATAAACTTAGGATTTTTAAAAGATAAAAACTTAGTTAAGAGTGTAAAAGAAGA
AATTTTACATATAAGAAATGAAAGTAACAAATTAAAAGAAGAGATTTTAAAAGAAAGTGGTTTTCTTCAAAATTAA

Upstream 100 bases:

>100_bases
TTTAAGGAAAATGAAGAGTATGAATGGAGTAGTATAGGTAAAAAGCTAAATAATATACTAAAATTAAAATAGGCAATAAG
ACATGACGGAGGGGTACACA

Downstream 100 bases:

>100_bases
GTAAAAGTAGAATAAAAAATTATTAGATAAATAATAAGGGGTCTATATCAAAATGTAATAAAAAACTTATAAACATATTT
CGAGAATTAATAGATTAAGC

Product: methenyltetrahydrofolate cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MKNEKIKDFIEDLGSSSSAPGGGAAAGIVGAVGVALTSMVYSLTVGKKAYEALSEENKKKLDENLENAKKSYNEMLDFMN
KDEEAFTALMDCYKLPKETCEEKSLRSEKIYECTLGAMMVPLELSRKALKFFDNVKFASKYGNKNLISDAVVSAIMLSAC
IDSSIVNVEINLGFLKDKNLVKSVKEEILHIRNESNKLKEEILKESGFLQN

Sequences:

>Translated_211_residues
MKNEKIKDFIEDLGSSSSAPGGGAAAGIVGAVGVALTSMVYSLTVGKKAYEALSEENKKKLDENLENAKKSYNEMLDFMN
KDEEAFTALMDCYKLPKETCEEKSLRSEKIYECTLGAMMVPLELSRKALKFFDNVKFASKYGNKNLISDAVVSAIMLSAC
IDSSIVNVEINLGFLKDKNLVKSVKEEILHIRNESNKLKEEILKESGFLQN
>Mature_211_residues
MKNEKIKDFIEDLGSSSSAPGGGAAAGIVGAVGVALTSMVYSLTVGKKAYEALSEENKKKLDENLENAKKSYNEMLDFMN
KDEEAFTALMDCYKLPKETCEEKSLRSEKIYECTLGAMMVPLELSRKALKFFDNVKFASKYGNKNLISDAVVSAIMLSAC
IDSSIVNVEINLGFLKDKNLVKSVKEEILHIRNESNKLKEEILKESGFLQN

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 23344; Mature: 23344

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNEKIKDFIEDLGSSSSAPGGGAAAGIVGAVGVALTSMVYSLTVGKKAYEALSEENKKK
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDENLENAKKSYNEMLDFMNKDEEAFTALMDCYKLPKETCEEKSLRSEKIYECTLGAMMV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
PLELSRKALKFFDNVKFASKYGNKNLISDAVVSAIMLSACIDSSIVNVEINLGFLKDKNL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHH
VKSVKEEILHIRNESNKLKEEILKESGFLQN
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKNEKIKDFIEDLGSSSSAPGGGAAAGIVGAVGVALTSMVYSLTVGKKAYEALSEENKKK
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDENLENAKKSYNEMLDFMNKDEEAFTALMDCYKLPKETCEEKSLRSEKIYECTLGAMMV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
PLELSRKALKFFDNVKFASKYGNKNLISDAVVSAIMLSACIDSSIVNVEINLGFLKDKNL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHH
VKSVKEEILHIRNESNKLKEEILKESGFLQN
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]