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The map label for this gene is ygbD [C]

Identifier: 18310777

GI number: 18310777

Start: 2073974

End: 2075197

Strand: Reverse

Name: ygbD [C]

Synonym: CPE1795

Alternate gene names: 18310777

Gene position: 2075197-2073974 (Counterclockwise)

Preceding gene: 18310778

Following gene: 18310776

Centisome position: 68.46

GC content: 30.88

Gene sequence:

>1224_bases
ATGAGATATATTGTTGTGGGGGCATCAGCTGCTGGAATAAGTGGAGCCAAAACACTTAGAGAACTTGACAAAGATGCAGA
AATAATATTAGTTTCAAAGGACGAAAATGTTTATTCAAGATGTATATTACATCATTACATAAGTGGTCATAGAGATATCG
AGGCTTTAGATTTTACAGATAGAGATTTCTTTGAAAAATATAATATAGAGTGGAAAAAAGGTTTAGAAGTTAAATCTATA
GATGATAGAGAGCATATAATAGGTCTTTCAAATGGAGAAAGCTTAAAATATGATAAGATATTATTAGCAACAGGAGCATC
AGCATTCATTCCTCCAGTAGAGAATTTAAGAGAAGCTAAAAATGTTGTTGGATTAAGAAACTTAGAGGATGCTATTAAAA
TTAAAGAAGAGGCAGAAAAGGTTAAAAACGTAGTTGTCTTAGGAGCAGGACTTGTTGGTATAGATGCCATAGCAGGACTT
GTTGGAAAAAATTTAAATGTTACTTTAGTTGAAATGGGGGATAGAGTCCTTCCAATTCAACTTGATAAATATGCTTCTTC
TAAATATGAGAAAAGATTTGAGGATGCTGGAGTTAAATTAAAACTTGGAGTTAGAGCGGAAAAAGTTTTAATTGATGAAA
ATAAAAATCCAAAGGCACTACTTATAAATACAGGAGAAGAAATTCCTTGCGAGCTTATAATAGTTGCAACTGGAGTTAGA
TCAAATGTAGCATTCTTAAAAGATAGTTCTATAGAAACAGATAGATTTGGATTAATAATAAATGAAAAAGGCGAAACTAA
TGCAAGAGATGTTTATGGAGCTGGAGATATAACTGGAAGAAATCCTATATGGCCAACTGCTGTAAAAGAAGGTATAATAG
CAGCAAACAATATGGTTGGTAATGAAATATTCATGGAAGATTTCTTTGGAAGTAAAAATACAATGAATTTCTTAGGACTT
ACAACAATGTCTTTAGGCGTTGTTAATGTTCCAGATGATTCTTATACAGAAGAAATTGATATTTCAGGAGAGAATTATAA
AAAGATAATCCATAAGGATGGAAAAATTTATGGAGCTATAATTCAAGGGGATTTATCTTATGCAGGAGTTTTAACTCAAC
TTATAAAAGAGAAGATACACGTGTCAAAGGTTAAAAAACCATTATTTGAAATTGACTATGCAGATTTCTTCAATATAAAA
GAAAATTTAGAGTACACATATTAA

Upstream 100 bases:

>100_bases
ATGAAATGTGATATGTGTGCAAGTACAAAAGAAAAAACTCCTCAATGCGTTGCAAAATGTCCAATGGGAGCAATAACTTT
AGAGGAGGTAGAAGAATAAT

Downstream 100 bases:

>100_bases
AATAAATTATAATTAAATTTATTTAATATAAGTATGTAAATTTTAATTTAGAAAATAATAAATTAAAGTTATAATTAGGA
GGAAAAGGCTTTGGCTAAGA

Product: nitrate reductase, NADH oxidase subunit

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MRYIVVGASAAGISGAKTLRELDKDAEIILVSKDENVYSRCILHHYISGHRDIEALDFTDRDFFEKYNIEWKKGLEVKSI
DDREHIIGLSNGESLKYDKILLATGASAFIPPVENLREAKNVVGLRNLEDAIKIKEEAEKVKNVVVLGAGLVGIDAIAGL
VGKNLNVTLVEMGDRVLPIQLDKYASSKYEKRFEDAGVKLKLGVRAEKVLIDENKNPKALLINTGEEIPCELIIVATGVR
SNVAFLKDSSIETDRFGLIINEKGETNARDVYGAGDITGRNPIWPTAVKEGIIAANNMVGNEIFMEDFFGSKNTMNFLGL
TTMSLGVVNVPDDSYTEEIDISGENYKKIIHKDGKIYGAIIQGDLSYAGVLTQLIKEKIHVSKVKKPLFEIDYADFFNIK
ENLEYTY

Sequences:

>Translated_407_residues
MRYIVVGASAAGISGAKTLRELDKDAEIILVSKDENVYSRCILHHYISGHRDIEALDFTDRDFFEKYNIEWKKGLEVKSI
DDREHIIGLSNGESLKYDKILLATGASAFIPPVENLREAKNVVGLRNLEDAIKIKEEAEKVKNVVVLGAGLVGIDAIAGL
VGKNLNVTLVEMGDRVLPIQLDKYASSKYEKRFEDAGVKLKLGVRAEKVLIDENKNPKALLINTGEEIPCELIIVATGVR
SNVAFLKDSSIETDRFGLIINEKGETNARDVYGAGDITGRNPIWPTAVKEGIIAANNMVGNEIFMEDFFGSKNTMNFLGL
TTMSLGVVNVPDDSYTEEIDISGENYKKIIHKDGKIYGAIIQGDLSYAGVLTQLIKEKIHVSKVKKPLFEIDYADFFNIK
ENLEYTY
>Mature_407_residues
MRYIVVGASAAGISGAKTLRELDKDAEIILVSKDENVYSRCILHHYISGHRDIEALDFTDRDFFEKYNIEWKKGLEVKSI
DDREHIIGLSNGESLKYDKILLATGASAFIPPVENLREAKNVVGLRNLEDAIKIKEEAEKVKNVVVLGAGLVGIDAIAGL
VGKNLNVTLVEMGDRVLPIQLDKYASSKYEKRFEDAGVKLKLGVRAEKVLIDENKNPKALLINTGEEIPCELIIVATGVR
SNVAFLKDSSIETDRFGLIINEKGETNARDVYGAGDITGRNPIWPTAVKEGIIAANNMVGNEIFMEDFFGSKNTMNFLGL
TTMSLGVVNVPDDSYTEEIDISGENYKKIIHKDGKIYGAIIQGDLSYAGVLTQLIKEKIHVSKVKKPLFEIDYADFFNIK
ENLEYTY

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=315, Percent_Identity=29.8412698412698, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI65787454, Length=315, Percent_Identity=29.8412698412698, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI21389617, Length=315, Percent_Identity=29.8412698412698, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1789765, Length=356, Percent_Identity=25.561797752809, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1789065, Length=304, Percent_Identity=24.6710526315789, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788892, Length=282, Percent_Identity=25.531914893617, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082354, Length=245, Percent_Identity=23.6734693877551, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=227, Percent_Identity=26.8722466960352, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24639257, Length=311, Percent_Identity=29.2604501607717, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281359715, Length=277, Percent_Identity=30.3249097472924, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281359713, Length=277, Percent_Identity=30.3249097472924, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24639250, Length=277, Percent_Identity=30.3249097472924, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI18543267, Length=277, Percent_Identity=30.3249097472924, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24639252, Length=277, Percent_Identity=30.3249097472924, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24585130, Length=312, Percent_Identity=28.525641025641, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28573993, Length=396, Percent_Identity=22.7272727272727, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24581020, Length=397, Percent_Identity=22.6700251889169, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 45141; Mature: 45141

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYIVVGASAAGISGAKTLRELDKDAEIILVSKDENVYSRCILHHYISGHRDIEALDFTD
CEEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCC
RDFFEKYNIEWKKGLEVKSIDDREHIIGLSNGESLKYDKILLATGASAFIPPVENLREAK
HHHHHHCCCCHHCCCEEEECCCHHHEEEECCCCCCEECEEEEECCCCCCCCCHHHHHHHH
NVVGLRNLEDAIKIKEEAEKVKNVVVLGAGLVGIDAIAGLVGKNLNVTLVEMGDRVLPIQ
HHCCCCCHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCEEEEEE
LDKYASSKYEKRFEDAGVKLKLGVRAEKVLIDENKNPKALLINTGEEIPCELIIVATGVR
EHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCEEEEECCCCCCEEEEEEEECCC
SNVAFLKDSSIETDRFGLIINEKGETNARDVYGAGDITGRNPIWPTAVKEGIIAANNMVG
CCEEEEECCCCCCCEEEEEEECCCCCCCCEECCCCCCCCCCCCCHHHHHCCEEEECCCCC
NEIFMEDFFGSKNTMNFLGLTTMSLGVVNVPDDSYTEEIDISGENYKKIIHKDGKIYGAI
CHHHHHHHCCCCCCCCEEEEEEHEEEEEECCCCCCCCEEECCCCHHHHHHHCCCCEEEEE
IQGDLSYAGVLTQLIKEKIHVSKVKKPLFEIDYADFFNIKENLEYTY
EECCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHCHHCCCCCCC
>Mature Secondary Structure
MRYIVVGASAAGISGAKTLRELDKDAEIILVSKDENVYSRCILHHYISGHRDIEALDFTD
CEEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCC
RDFFEKYNIEWKKGLEVKSIDDREHIIGLSNGESLKYDKILLATGASAFIPPVENLREAK
HHHHHHCCCCHHCCCEEEECCCHHHEEEECCCCCCEECEEEEECCCCCCCCCHHHHHHHH
NVVGLRNLEDAIKIKEEAEKVKNVVVLGAGLVGIDAIAGLVGKNLNVTLVEMGDRVLPIQ
HHCCCCCHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCEEEEEE
LDKYASSKYEKRFEDAGVKLKLGVRAEKVLIDENKNPKALLINTGEEIPCELIIVATGVR
EHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCEEEEECCCCCCEEEEEEEECCC
SNVAFLKDSSIETDRFGLIINEKGETNARDVYGAGDITGRNPIWPTAVKEGIIAANNMVG
CCEEEEECCCCCCCEEEEEEECCCCCCCCEECCCCCCCCCCCCCHHHHHCCEEEECCCCC
NEIFMEDFFGSKNTMNFLGLTTMSLGVVNVPDDSYTEEIDISGENYKKIIHKDGKIYGAI
CHHHHHHHCCCCCCCCEEEEEEHEEEEEECCCCCCCCEEECCCCHHHHHHHCCCCEEEEE
IQGDLSYAGVLTQLIKEKIHVSKVKKPLFEIDYADFFNIKENLEYTY
EECCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]