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The map label for this gene is nrdR

Identifier: 18310741

GI number: 18310741

Start: 2038676

End: 2039125

Strand: Reverse

Name: nrdR

Synonym: CPE1759

Alternate gene names: 18310741

Gene position: 2039125-2038676 (Counterclockwise)

Preceding gene: 18310742

Following gene: 18310740

Centisome position: 67.27

GC content: 28.89

Gene sequence:

>450_bases
ATGAGATGTCCTTACTGTTCTTATGAAGAAAGTAAAGTTGTGGATTCTAGATCTGCAGAAGATTATAATGCAATTAGAAG
AAGAAGAGAATGTTTAAGATGTTCTAAGAGATACACAACTTACGAAAAGGTAGAAGATATACCAATACTTGTTATAAAAA
AGGATTTAAGTAGAGAAAGTTTCAATAAAGAAAAAATCATAAGCGGATTAATTAAAGCGTGTCAAAAGAGACCTGTATCT
AGGGCTCAAATAGAAGAAATAGCAGCTGATATTGAACGAAACATAAGTAATAAAATGATGGTAGAAATAAAGTCTGATTA
CATAGGTGAAATGATAATGGAGAGACTTAAGGATATAGACGAAGTTTCATACGTAAGATTTGCTTCTGTATATAGACAAT
TTAAAGATATTAATACCTTTATGGAAGAAATAAAAAGTTTAATGAAATAA

Upstream 100 bases:

>100_bases
AAAGGGAAAAATATACTAGATGTTCAAAAATATATATAGAAATTAAGTAAAAAAGAAGGTATAATATTATTACAACTTAG
AGAAAGGCGTGGATTTTAAA

Downstream 100 bases:

>100_bases
TTTTAAGCTATCTTAAAGAGAGTTCTTTAAGATGGCTTTTTTATTTGTTTTAATTTATCCATATACTTAAATAATATTTA
ACTTGAATTTAATTTAACAA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRCPYCSYEESKVVDSRSAEDYNAIRRRRECLRCSKRYTTYEKVEDIPILVIKKDLSRESFNKEKIISGLIKACQKRPVS
RAQIEEIAADIERNISNKMMVEIKSDYIGEMIMERLKDIDEVSYVRFASVYRQFKDINTFMEEIKSLMK

Sequences:

>Translated_149_residues
MRCPYCSYEESKVVDSRSAEDYNAIRRRRECLRCSKRYTTYEKVEDIPILVIKKDLSRESFNKEKIISGLIKACQKRPVS
RAQIEEIAADIERNISNKMMVEIKSDYIGEMIMERLKDIDEVSYVRFASVYRQFKDINTFMEEIKSLMK
>Mature_149_residues
MRCPYCSYEESKVVDSRSAEDYNAIRRRRECLRCSKRYTTYEKVEDIPILVIKKDLSRESFNKEKIISGLIKACQKRPVS
RAQIEEIAADIERNISNKMMVEIKSDYIGEMIMERLKDIDEVSYVRFASVYRQFKDINTFMEEIKSLMK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=44.2176870748299, Blast_Score=133, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_CLOP1 (Q0TPJ5)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696445.1
- STRING:   Q0TPJ5
- GeneID:   4201732
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2012
- TIGR:   CPF_2012
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   CPER195103:CPF_2012-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17718; Mature: 17718

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPYCSYEESKVVDSRSAEDYNAIRRRRECLRCSKRYTTYEKVEDIPILVIKKDLSRES
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEEECHHCHHH
FNKEKIISGLIKACQKRPVSRAQIEEIAADIERNISNKMMVEIKSDYIGEMIMERLKDID
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
EVSYVRFASVYRQFKDINTFMEEIKSLMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRCPYCSYEESKVVDSRSAEDYNAIRRRRECLRCSKRYTTYEKVEDIPILVIKKDLSRES
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEEECHHCHHH
FNKEKIISGLIKACQKRPVSRAQIEEIAADIERNISNKMMVEIKSDYIGEMIMERLKDID
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
EVSYVRFASVYRQFKDINTFMEEIKSLMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA