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The map label for this gene is rsmB [H]

Identifier: 18310723

GI number: 18310723

Start: 2018196

End: 2019524

Strand: Reverse

Name: rsmB [H]

Synonym: CPE1741

Alternate gene names: 18310723

Gene position: 2019524-2018196 (Counterclockwise)

Preceding gene: 18310724

Following gene: 18310722

Centisome position: 66.62

GC content: 27.69

Gene sequence:

>1329_bases
ATGAATGCAAGAAAAATAATAGTTGAAATATTAGACAATGTCTTATTAAATGGAGCATATTCAAATATAGAAATAAATAA
GCAATTTGCATCTAATGATATAGATCCAAAAGATAAGGGATTAATAACAGAAGTTGTTTATGGAACAATAAAATACAAAA
AAATGATAGATATAATTCTTTCAAGTTTTGTTGCTGATATTGGTAAGATAGATGAGAGTGTAGTAAACATATTAAGAAGT
GCTATATATCAAATGAAATTCTTAGATAGAGTTCCTCCATATGCAATAGTTAATGAAGCTGTAAACTTAACTAAAGAAAC
TGAACCTAATTTAGCTAAGTTTATAAATGGGGTTTTAAGAAATTATTTAAGAAATGAAAATAAAAACTTTAAAGTTGGAT
TAAGAAATAACGAAGCTTTATGTTATGACTTTTCTTTTGATAGATGGATGATAGAAATGTTCATAAAACAATATGGAAAA
GAGGATGCTTTAAGAATACTTAGAGGATTAAATACAGTTCCATATGTAACAGTTAGAGTTAATACATGTAAAGCTGATTA
TGATGAAGTTTATGAAAGACTTGAAGAAGAAGGATATGATATAGAGGAAGGTGCATTTTCACCAGAAGCTATCATAATCA
AAAAAGGTAGTGCAATAGAGAAAAATAAACTTTATCAAGAAGGTTTAATAACAGTTCAAGATGAAAGTGCTATGTTAGTA
GCTCCTTTATTTGATTTAAAGGGTGATGAACAAGTTATGGATCTATGTAGTGCACCAGGAACTAAAGCAACTCATATAGG
CGAATTAATGATGAATAAAGGAAAAGTAGTGGCTTTTGATATTCATGACCATAAGTTAGCTTTAATAAAGGAAAATATAG
ATAGATTAGGATTAACTAATGTTGAAGTTGAATTAGGAGATGCTACAAAGATAAATTCTAAGTATATAAATTGGGCTGAT
AGAATATTATTAGATGTACCTTGCTCAGGACTTGGAATTATAAGAAAGAAACCAGAAATAAAATGGAATAAAAAGAACAA
TGATTTAACAGAAGTTGTTAAGGTTCAAAAAGAAATATTAAAAAATGCTTGGAATTATTTAAGAGAAGGTGGAGAATTAG
TTTACTCTACTTGTACTTTAAATAAAAAAGAAAATGAAGAAGTTATAGATTGGTTCGTAGAGAGAAATTCAGACTGCGAA
GTAGAAAAAGTATTTTTAGGTAAGGCTGATAATGTGGTATATAATGATAACGGAAGTGTTACCATATTACCTAATAAGTA
CATGGATGGTTTCTTTATTGCTAAGCTTAAGAAAAAAGAAAGTAAATAG

Upstream 100 bases:

>100_bases
GCAGCATTAACTTATGTTGCAGCAACACTTATGGCTGTTTTACAATTAGTAAGACTTATAGCTATAAGTAACAGAAATTC
AAATGATTAGAGGTTAAAAT

Downstream 100 bases:

>100_bases
CAAAGAGGATAAACATGGAAGGTGAGACTGTATGAAAAACATCTTAGATTTTACATTAGAAGAGTTAAAAGAGTGGATGA
AGGAAAATGGAGAGAGTGCT

Product: RNA-binding Sun protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNARKIIVEILDNVLLNGAYSNIEINKQFASNDIDPKDKGLITEVVYGTIKYKKMIDIILSSFVADIGKIDESVVNILRS
AIYQMKFLDRVPPYAIVNEAVNLTKETEPNLAKFINGVLRNYLRNENKNFKVGLRNNEALCYDFSFDRWMIEMFIKQYGK
EDALRILRGLNTVPYVTVRVNTCKADYDEVYERLEEEGYDIEEGAFSPEAIIIKKGSAIEKNKLYQEGLITVQDESAMLV
APLFDLKGDEQVMDLCSAPGTKATHIGELMMNKGKVVAFDIHDHKLALIKENIDRLGLTNVEVELGDATKINSKYINWAD
RILLDVPCSGLGIIRKKPEIKWNKKNNDLTEVVKVQKEILKNAWNYLREGGELVYSTCTLNKKENEEVIDWFVERNSDCE
VEKVFLGKADNVVYNDNGSVTILPNKYMDGFFIAKLKKKESK

Sequences:

>Translated_442_residues
MNARKIIVEILDNVLLNGAYSNIEINKQFASNDIDPKDKGLITEVVYGTIKYKKMIDIILSSFVADIGKIDESVVNILRS
AIYQMKFLDRVPPYAIVNEAVNLTKETEPNLAKFINGVLRNYLRNENKNFKVGLRNNEALCYDFSFDRWMIEMFIKQYGK
EDALRILRGLNTVPYVTVRVNTCKADYDEVYERLEEEGYDIEEGAFSPEAIIIKKGSAIEKNKLYQEGLITVQDESAMLV
APLFDLKGDEQVMDLCSAPGTKATHIGELMMNKGKVVAFDIHDHKLALIKENIDRLGLTNVEVELGDATKINSKYINWAD
RILLDVPCSGLGIIRKKPEIKWNKKNNDLTEVVKVQKEILKNAWNYLREGGELVYSTCTLNKKENEEVIDWFVERNSDCE
VEKVFLGKADNVVYNDNGSVTILPNKYMDGFFIAKLKKKESK
>Mature_442_residues
MNARKIIVEILDNVLLNGAYSNIEINKQFASNDIDPKDKGLITEVVYGTIKYKKMIDIILSSFVADIGKIDESVVNILRS
AIYQMKFLDRVPPYAIVNEAVNLTKETEPNLAKFINGVLRNYLRNENKNFKVGLRNNEALCYDFSFDRWMIEMFIKQYGK
EDALRILRGLNTVPYVTVRVNTCKADYDEVYERLEEEGYDIEEGAFSPEAIIIKKGSAIEKNKLYQEGLITVQDESAMLV
APLFDLKGDEQVMDLCSAPGTKATHIGELMMNKGKVVAFDIHDHKLALIKENIDRLGLTNVEVELGDATKINSKYINWAD
RILLDVPCSGLGIIRKKPEIKWNKKNNDLTEVVKVQKEILKNAWNYLREGGELVYSTCTLNKKENEEVIDWFVERNSDCE
VEKVFLGKADNVVYNDNGSVTILPNKYMDGFFIAKLKKKESK

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=343, Percent_Identity=29.7376093294461, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI76150623, Length=343, Percent_Identity=29.7376093294461, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI270288818, Length=241, Percent_Identity=28.6307053941909, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI8922322, Length=241, Percent_Identity=28.6307053941909, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI23199998, Length=241, Percent_Identity=28.6307053941909, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI270288816, Length=241, Percent_Identity=28.6307053941909, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI32698918, Length=172, Percent_Identity=33.7209302325581, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI301336155, Length=207, Percent_Identity=31.8840579710145, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI39995082, Length=207, Percent_Identity=31.8840579710145, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI11545785, Length=322, Percent_Identity=24.223602484472, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI2367212, Length=444, Percent_Identity=30.6306306306306, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI87081985, Length=281, Percent_Identity=33.8078291814947, Blast_Score=152, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17536757, Length=316, Percent_Identity=27.8481012658228, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71998419, Length=242, Percent_Identity=29.3388429752066, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115534021, Length=172, Percent_Identity=32.5581395348837, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25143471, Length=176, Percent_Identity=32.3863636363636, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324268, Length=315, Percent_Identity=28.8888888888889, Blast_Score=129, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6319447, Length=179, Percent_Identity=32.4022346368715, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324306, Length=218, Percent_Identity=25.6880733944954, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI22024126, Length=314, Percent_Identity=27.7070063694268, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24668781, Length=190, Percent_Identity=31.0526315789474, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356513, Length=190, Percent_Identity=31.0526315789474, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355201, Length=199, Percent_Identity=31.1557788944724, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356579, Length=228, Percent_Identity=25.8771929824561, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 50430; Mature: 50430

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARKIIVEILDNVLLNGAYSNIEINKQFASNDIDPKDKGLITEVVYGTIKYKKMIDIIL
CCHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SSFVADIGKIDESVVNILRSAIYQMKFLDRVPPYAIVNEAVNLTKETEPNLAKFINGVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
NYLRNENKNFKVGLRNNEALCYDFSFDRWMIEMFIKQYGKEDALRILRGLNTVPYVTVRV
HHHHCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEE
NTCKADYDEVYERLEEEGYDIEEGAFSPEAIIIKKGSAIEKNKLYQEGLITVQDESAMLV
EECCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCEEEECCCCEEE
APLFDLKGDEQVMDLCSAPGTKATHIGELMMNKGKVVAFDIHDHKLALIKENIDRLGLTN
EEECCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCE
VEVELGDATKINSKYINWADRILLDVPCSGLGIIRKKPEIKWNKKNNDLTEVVKVQKEIL
EEEEECCCCCCCCHHHCHHHEEEEECCCCCCEEEECCCCCEECCCCCHHHHHHHHHHHHH
KNAWNYLREGGELVYSTCTLNKKENEEVIDWFVERNSDCEVEKVFLGKADNVVYNDNGSV
HHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCE
TILPNKYMDGFFIAKLKKKESK
EECCCCCCCCCCEEEHHHCCCC
>Mature Secondary Structure
MNARKIIVEILDNVLLNGAYSNIEINKQFASNDIDPKDKGLITEVVYGTIKYKKMIDIIL
CCHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SSFVADIGKIDESVVNILRSAIYQMKFLDRVPPYAIVNEAVNLTKETEPNLAKFINGVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
NYLRNENKNFKVGLRNNEALCYDFSFDRWMIEMFIKQYGKEDALRILRGLNTVPYVTVRV
HHHHCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEE
NTCKADYDEVYERLEEEGYDIEEGAFSPEAIIIKKGSAIEKNKLYQEGLITVQDESAMLV
EECCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCEEEECCCCEEE
APLFDLKGDEQVMDLCSAPGTKATHIGELMMNKGKVVAFDIHDHKLALIKENIDRLGLTN
EEECCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCE
VEVELGDATKINSKYINWADRILLDVPCSGLGIIRKKPEIKWNKKNNDLTEVVKVQKEIL
EEEEECCCCCCCCHHHCHHHEEEEECCCCCCEEEECCCCCEECCCCCHHHHHHHHHHHHH
KNAWNYLREGGELVYSTCTLNKKENEEVIDWFVERNSDCEVEKVFLGKADNVVYNDNGSV
HHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCE
TILPNKYMDGFFIAKLKKKESK
EECCCCCCCCCCEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]