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The map label for this gene is polC

Identifier: 18310673

GI number: 18310673

Start: 1966403

End: 1970752

Strand: Reverse

Name: polC

Synonym: CPE1691

Alternate gene names: 18310673

Gene position: 1970752-1966403 (Counterclockwise)

Preceding gene: 18310674

Following gene: 18310672

Centisome position: 65.01

GC content: 31.45

Gene sequence:

>4350_bases
TTGAGTAACGAGTTTGTTAAACAGATTAACAGATCCATAAAATCAGATGATAATCTTAATGATTTAGAGTTTGAAATAAC
TAAGTTTCAATTGTTGAAGAAAAGCAATACTTTAAGAACCATAATAAAAAGTAAAGATCAATTATCAGAAGAACAAAAGA
AAATAATTAAGCAATATATAAAAAAAGCTATAGGTTTTGAAATAAATATAGAGATTATGTATTACATAGATATTTCTGAT
ATAACTTTAAAACAGGTAGTAGATCAGCATTGGAATCATGTTTGTGAAAAAATTATAGAGAAACATCCTGTTTTAAAAGA
AGTTTTACTTAATTCTCCTATAGTAATTGAAGGAGAAAAAATAATTATAAAAAATGGTTCTGAGTTTTTATGTACTTTTG
TTAATAAGAAACATATAGATAGAGAGATTAAGGGATATATAAAATCATTCTTTGGAATAAATTCTTTAGTAGAAGTTAAA
TATGATGAAAGTTTAGCTAATAAGAATTACAATGATGAAAAGTTAAATGAAAACAAAGAAATAGCTAAAAAAGTTATAGA
AACTATGAAAGCTCAAGCTGCTCAAGAAAAGCCTGTTAAAAAAGAAAGTAGTGATAATAAACATAAATCTAATGGTGGCA
ATAAAGGTGGTTATGAGAAGAAATCTTATAAAGATGAGCCTAAGAATGAAAATACTATACTTGGAAGAAATATTCAAGGA
GATACTATAGATATAAGCAGTATAGATATGGGGTCTGGAATTGTTACTATTTCAGGAGATGTATTTAAAACTGATATTTT
TGAAACTAAGACAGGTAGAATAATACTTACATTCTTCATAACAGACTATACAAGTTCCATAGCCGTTAAATGCTTCTTAA
GAGATAAGGATAAAGAACATGTTTTAGAAAATGTTAAAAAAGGTCTTTATTGTAAAGTAAGAGGGGAAGCTACTATGGAT
CCTTATGCTAAGGAAGTTGTAATAATGGCTAGGGATATAAATAAGCTTACAAAAATAGAGCGTATGGATACAGCAGAGGA
AAAAAGAGTAGAACTTCATATGCATACAACTATGAGCTCAATGGATGCCGTAACTGCTGCAAGTAAAATTGTTGAGAGAG
CAGCAAAGTTTGGCCATAAGGCTGTAGCCATAACAGACCATGGAGTTGTTCAGGCTTTTCCAGATGCTCAAATAGCGGCT
AAAAAGAATAACATAAAAGTTATTTATGGAGTAGAGGGATATTTAGCTGATAATGGAACACCTATAGTTATTAATGGGCA
TGAGGAATCTTTTGATGATGAGTATGTGGTTTTTGATATAGAAACCACAGGTTTTTCAAGTAAAAATGATAAGATTATAG
AAATTGGTGCTGTTAAGTTAAAGGATGGAGAAATAGTAGATTCATTTAGTACTTTTGTTGATCCAAAGGTAAATATTCCA
TATAAGATTACAGAGCTTACAAGTATAACTCAAAATATGGTTAATGGACAGCCTACTATAGATGAAGTGCTTCCTAAATT
TATGGAGTTTGTAGGAAATTCTGTATTAGTAGCCCATAATGCTGCCTTTGACGTTGGTTTTATAAAAAAGAACTTAATGG
ATATGGGAAAAACTTTAAAGAATCCTGTAATGGATACTGTTCCTTTAGCTAGATATCTTTATCCAGATTTAAAAAAGGTT
AAGTTAAATCTAGTTGCTAAACATTTAGGAATTAGCCTTGAAAATCACCATAGAGCCGTTGATGATGCAAAGGCTACTGC
GGAGATATTAAAGTTTTCTTTCAAAAAGATGAAAGAAGAAATGGATATTCATGATGTTAAAACTCTAAATGAAAAGTATT
TATCAAATATAGATGTAAAGAAACTTCCTCTACATCACATAATAATATTAGCTAAAAATCAAACTGGAATTAAGAATTTA
TATAAATTAGTTTCTATGGCTCACTTAGATTACTTTGCTAGAAGGCCAAGACTTCCTAAAAGTATAATAACTGAGTATAG
AGAAGGATTAATAATTGGTTCAGCTTGTGAAGCAGGGCAATTATATAAGGCGGTTTTAGAAGGCAAGACAGATGGGGAAT
TAAAAGAAATAGCATCTTTTTATGACTATCTAGAAATTCAGCCAATACAAAATAATGAATTCCTTATAAGAAAAGGAAAT
GTAAAGGATGAAGAAGAGCTTAGAGAGTTAAATAGAAAAATATATGATTTAGGAAAGGAAATGGATAAACCGGTAGTTGC
TACATGTGATTGTCATTTCTTAGATCCTAATGATGAAGTATTTAGAAGAATAATAATGGCTGGTCAAGGATATGGAGATG
CAGATAATCAACCACCTTTATATTTTAGAACTACTAATGAAATGATGAAAGAGTTTGAATATTTAGGAGAAGAGGCTTGC
AGGGAAGTTGTAATAGAAAATACTCAGAAGATAGCTGATATGGTTGAGGCTGTAAAACCTATACCAGATGAAACATTTCC
TCCTAAAATAGAGGGGGCTGAGGAAGAAATAAGAAACATGACTATGAATAAGGTTCATAGTATATATGGAGAAAATCTTC
CTGAAGTTGTTCAAAAGAGATTAGATAAAGAACTTAATTCTATAATAAATAATGGATATGCGGTGCTTTATCTTATAGCT
CAAAAATTAGTTGCTAAATCCTTAGAAGACGGATACCTAGTTGGTTCAAGGGGGTCTGTTGGTTCCTCTTTCGTAGCAAC
AATGTCAGATATAACAGAGGTTAATGGATTACCACCTCATTATGTTTGTCCAAATTGTAAGAAATCAGAATTTTTCTTAG
ATGGTTCTATAAGTTCAGGAGCAGATTTACCAGATAAAAATTGTCCTGATTGTGGAGCTAAGTATATTAAGGATGGCCAT
GATATTCCTTTCGAAACATTCTTAGGTTTTGAAGGGGATAAAGAACCAGATATAGACCTTAACTTCTCAGGGGAATACCA
AGCTGTTGTACATAAGTACACAGAGGTTCTTTTCGGAAAAGGATATGTATTTAAAGCTGGAACTATAGGTACAGTAGCTG
AAAAAACAGCTTATGGTTTTGTAAAAAAATACCTTCAAGAAAGAGGATTAGTTGTATCTCAAGCTGAAATAGAAAGGCTT
ACTATTGGATGTACTGGAATAAAAAGAACTAGTGGACAGCATCCTGGTGGAATCATGGTTGTTCCAAATGACAATGAAAT
ATATAATTTTTGTCCAATACAACATCCAGCTGATGATGTTAACACAGATATTATAACAACTCACTTTGATTACCATTCAA
TAAGTGGTAGACTTCTTAAGCTTGATATACTTGGACACGACGACCCGACCGTTCTTAGAATGCTTCAAGACTTAACTGGC
TTAGATCCTAAGACAATACCTTTAAATGATCCTAAGGTTATAAGTTTATTTACATCACCAGATGCCTTAGGGGTAACTAA
AGAAGAATTAGGATGTGAAGTTGGTAGTTATGGACTTCCTGAGTTCGGTACTAAATTCGTTAGACAGATGCTAGTTGATA
CTCAACCTAAGAGTTTTGCAGACCTTGTGAGAATATCTGGACTTTCACATGGTACTGATGTTTGGCTTAATAATGCTCAG
TACTTTATTAAAGAAGGTTACACTACACTAAAAGATTGTATAGCAACAAGAGACGATATTATGGTTTATCTTATGTATAA
AGATCTTCCTCCTAAGACAGCCTTTACTATAATGGAAAAGGTAAGAAAAGGAAAAGGGCTTAGTGAAGAGGATGAAGCTT
TAATGAGAGAGAAAAATGTACCAGATTGGTATATTGAATCTTGTAAAAGAATAAAATACATGTTCCCTAAAGGCCATGCT
GTTGCATATGTTATGATGGCAGTTAGAATAGCATATTATAAAGTTTATTATCCAGAAGCATATTACACAACATACTTTAC
AGTAAGAGCTGATGATTTCGATGCAGACTTAATTTGTAAGGGTGAAGAAGCAATAAAGGCAAAAATGGAAGAGCTAAATT
CTTTAGGAAATAACATATCAGTAAAAGAAAAAGGGCTTTTAACTATTTTAGAAATTTCTTATGAAATGTATAAAAGAGGA
TTGAATTTCTTAAAGGTTGATTTATATAAATCAGAAGCAACTAAGTTTAAGATAGAAGAAGATGGTATAAGACCTCCATT
AAATGCTCTTCAAGGAGTTGGAGACAATGCTGCAAAAAGTATAGTTGAATGTAGAGTTAATGGAGAGTTTATTTCAAAGG
AAGATTTAAGACTTAGATCTAAGGTTTCAAAGACTGTAATAGAAACTTTAGATAATCATGGATGCCTAGAAGGAATGCAA
GAAAGTAACCAACTTAGTTTGTTTGGCTAA

Upstream 100 bases:

>100_bases
TAAAGATAATAGAAACAATATAATTTAAAGGAGGGATTAATATCCCTTCTTTATGTCGTATAGGGATAAATTAAAATAAA
ATTCAAAGGAGGCTTAGATT

Downstream 100 bases:

>100_bases
TTTTAAAAATTTCTTGTAATATAAAATATACTATGTTACTATATAAGTAGAAGTTTTTTACTAATAGTTTGAGGTAAAGG
AGTGGGACAGAAAAGCCCGC

Product: DNA polymerase III PolC

Products: NA

Alternate protein names: PolIII

Number of amino acids: Translated: 1449; Mature: 1448

Protein sequence:

>1449_residues
MSNEFVKQINRSIKSDDNLNDLEFEITKFQLLKKSNTLRTIIKSKDQLSEEQKKIIKQYIKKAIGFEINIEIMYYIDISD
ITLKQVVDQHWNHVCEKIIEKHPVLKEVLLNSPIVIEGEKIIIKNGSEFLCTFVNKKHIDREIKGYIKSFFGINSLVEVK
YDESLANKNYNDEKLNENKEIAKKVIETMKAQAAQEKPVKKESSDNKHKSNGGNKGGYEKKSYKDEPKNENTILGRNIQG
DTIDISSIDMGSGIVTISGDVFKTDIFETKTGRIILTFFITDYTSSIAVKCFLRDKDKEHVLENVKKGLYCKVRGEATMD
PYAKEVVIMARDINKLTKIERMDTAEEKRVELHMHTTMSSMDAVTAASKIVERAAKFGHKAVAITDHGVVQAFPDAQIAA
KKNNIKVIYGVEGYLADNGTPIVINGHEESFDDEYVVFDIETTGFSSKNDKIIEIGAVKLKDGEIVDSFSTFVDPKVNIP
YKITELTSITQNMVNGQPTIDEVLPKFMEFVGNSVLVAHNAAFDVGFIKKNLMDMGKTLKNPVMDTVPLARYLYPDLKKV
KLNLVAKHLGISLENHHRAVDDAKATAEILKFSFKKMKEEMDIHDVKTLNEKYLSNIDVKKLPLHHIIILAKNQTGIKNL
YKLVSMAHLDYFARRPRLPKSIITEYREGLIIGSACEAGQLYKAVLEGKTDGELKEIASFYDYLEIQPIQNNEFLIRKGN
VKDEEELRELNRKIYDLGKEMDKPVVATCDCHFLDPNDEVFRRIIMAGQGYGDADNQPPLYFRTTNEMMKEFEYLGEEAC
REVVIENTQKIADMVEAVKPIPDETFPPKIEGAEEEIRNMTMNKVHSIYGENLPEVVQKRLDKELNSIINNGYAVLYLIA
QKLVAKSLEDGYLVGSRGSVGSSFVATMSDITEVNGLPPHYVCPNCKKSEFFLDGSISSGADLPDKNCPDCGAKYIKDGH
DIPFETFLGFEGDKEPDIDLNFSGEYQAVVHKYTEVLFGKGYVFKAGTIGTVAEKTAYGFVKKYLQERGLVVSQAEIERL
TIGCTGIKRTSGQHPGGIMVVPNDNEIYNFCPIQHPADDVNTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTG
LDPKTIPLNDPKVISLFTSPDALGVTKEELGCEVGSYGLPEFGTKFVRQMLVDTQPKSFADLVRISGLSHGTDVWLNNAQ
YFIKEGYTTLKDCIATRDDIMVYLMYKDLPPKTAFTIMEKVRKGKGLSEEDEALMREKNVPDWYIESCKRIKYMFPKGHA
VAYVMMAVRIAYYKVYYPEAYYTTYFTVRADDFDADLICKGEEAIKAKMEELNSLGNNISVKEKGLLTILEISYEMYKRG
LNFLKVDLYKSEATKFKIEEDGIRPPLNALQGVGDNAAKSIVECRVNGEFISKEDLRLRSKVSKTVIETLDNHGCLEGMQ
ESNQLSLFG

Sequences:

>Translated_1449_residues
MSNEFVKQINRSIKSDDNLNDLEFEITKFQLLKKSNTLRTIIKSKDQLSEEQKKIIKQYIKKAIGFEINIEIMYYIDISD
ITLKQVVDQHWNHVCEKIIEKHPVLKEVLLNSPIVIEGEKIIIKNGSEFLCTFVNKKHIDREIKGYIKSFFGINSLVEVK
YDESLANKNYNDEKLNENKEIAKKVIETMKAQAAQEKPVKKESSDNKHKSNGGNKGGYEKKSYKDEPKNENTILGRNIQG
DTIDISSIDMGSGIVTISGDVFKTDIFETKTGRIILTFFITDYTSSIAVKCFLRDKDKEHVLENVKKGLYCKVRGEATMD
PYAKEVVIMARDINKLTKIERMDTAEEKRVELHMHTTMSSMDAVTAASKIVERAAKFGHKAVAITDHGVVQAFPDAQIAA
KKNNIKVIYGVEGYLADNGTPIVINGHEESFDDEYVVFDIETTGFSSKNDKIIEIGAVKLKDGEIVDSFSTFVDPKVNIP
YKITELTSITQNMVNGQPTIDEVLPKFMEFVGNSVLVAHNAAFDVGFIKKNLMDMGKTLKNPVMDTVPLARYLYPDLKKV
KLNLVAKHLGISLENHHRAVDDAKATAEILKFSFKKMKEEMDIHDVKTLNEKYLSNIDVKKLPLHHIIILAKNQTGIKNL
YKLVSMAHLDYFARRPRLPKSIITEYREGLIIGSACEAGQLYKAVLEGKTDGELKEIASFYDYLEIQPIQNNEFLIRKGN
VKDEEELRELNRKIYDLGKEMDKPVVATCDCHFLDPNDEVFRRIIMAGQGYGDADNQPPLYFRTTNEMMKEFEYLGEEAC
REVVIENTQKIADMVEAVKPIPDETFPPKIEGAEEEIRNMTMNKVHSIYGENLPEVVQKRLDKELNSIINNGYAVLYLIA
QKLVAKSLEDGYLVGSRGSVGSSFVATMSDITEVNGLPPHYVCPNCKKSEFFLDGSISSGADLPDKNCPDCGAKYIKDGH
DIPFETFLGFEGDKEPDIDLNFSGEYQAVVHKYTEVLFGKGYVFKAGTIGTVAEKTAYGFVKKYLQERGLVVSQAEIERL
TIGCTGIKRTSGQHPGGIMVVPNDNEIYNFCPIQHPADDVNTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTG
LDPKTIPLNDPKVISLFTSPDALGVTKEELGCEVGSYGLPEFGTKFVRQMLVDTQPKSFADLVRISGLSHGTDVWLNNAQ
YFIKEGYTTLKDCIATRDDIMVYLMYKDLPPKTAFTIMEKVRKGKGLSEEDEALMREKNVPDWYIESCKRIKYMFPKGHA
VAYVMMAVRIAYYKVYYPEAYYTTYFTVRADDFDADLICKGEEAIKAKMEELNSLGNNISVKEKGLLTILEISYEMYKRG
LNFLKVDLYKSEATKFKIEEDGIRPPLNALQGVGDNAAKSIVECRVNGEFISKEDLRLRSKVSKTVIETLDNHGCLEGMQ
ESNQLSLFG
>Mature_1448_residues
SNEFVKQINRSIKSDDNLNDLEFEITKFQLLKKSNTLRTIIKSKDQLSEEQKKIIKQYIKKAIGFEINIEIMYYIDISDI
TLKQVVDQHWNHVCEKIIEKHPVLKEVLLNSPIVIEGEKIIIKNGSEFLCTFVNKKHIDREIKGYIKSFFGINSLVEVKY
DESLANKNYNDEKLNENKEIAKKVIETMKAQAAQEKPVKKESSDNKHKSNGGNKGGYEKKSYKDEPKNENTILGRNIQGD
TIDISSIDMGSGIVTISGDVFKTDIFETKTGRIILTFFITDYTSSIAVKCFLRDKDKEHVLENVKKGLYCKVRGEATMDP
YAKEVVIMARDINKLTKIERMDTAEEKRVELHMHTTMSSMDAVTAASKIVERAAKFGHKAVAITDHGVVQAFPDAQIAAK
KNNIKVIYGVEGYLADNGTPIVINGHEESFDDEYVVFDIETTGFSSKNDKIIEIGAVKLKDGEIVDSFSTFVDPKVNIPY
KITELTSITQNMVNGQPTIDEVLPKFMEFVGNSVLVAHNAAFDVGFIKKNLMDMGKTLKNPVMDTVPLARYLYPDLKKVK
LNLVAKHLGISLENHHRAVDDAKATAEILKFSFKKMKEEMDIHDVKTLNEKYLSNIDVKKLPLHHIIILAKNQTGIKNLY
KLVSMAHLDYFARRPRLPKSIITEYREGLIIGSACEAGQLYKAVLEGKTDGELKEIASFYDYLEIQPIQNNEFLIRKGNV
KDEEELRELNRKIYDLGKEMDKPVVATCDCHFLDPNDEVFRRIIMAGQGYGDADNQPPLYFRTTNEMMKEFEYLGEEACR
EVVIENTQKIADMVEAVKPIPDETFPPKIEGAEEEIRNMTMNKVHSIYGENLPEVVQKRLDKELNSIINNGYAVLYLIAQ
KLVAKSLEDGYLVGSRGSVGSSFVATMSDITEVNGLPPHYVCPNCKKSEFFLDGSISSGADLPDKNCPDCGAKYIKDGHD
IPFETFLGFEGDKEPDIDLNFSGEYQAVVHKYTEVLFGKGYVFKAGTIGTVAEKTAYGFVKKYLQERGLVVSQAEIERLT
IGCTGIKRTSGQHPGGIMVVPNDNEIYNFCPIQHPADDVNTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTGL
DPKTIPLNDPKVISLFTSPDALGVTKEELGCEVGSYGLPEFGTKFVRQMLVDTQPKSFADLVRISGLSHGTDVWLNNAQY
FIKEGYTTLKDCIATRDDIMVYLMYKDLPPKTAFTIMEKVRKGKGLSEEDEALMREKNVPDWYIESCKRIKYMFPKGHAV
AYVMMAVRIAYYKVYYPEAYYTTYFTVRADDFDADLICKGEEAIKAKMEELNSLGNNISVKEKGLLTILEISYEMYKRGL
NFLKVDLYKSEATKFKIEEDGIRPPLNALQGVGDNAAKSIVECRVNGEFISKEDLRLRSKVSKTVIETLDNHGCLEGMQE
SNQLSLFG

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Escherichia coli, GI1786381, Length=929, Percent_Identity=22.2820236813778, Blast_Score=115, Evalue=3e-26,
Organism=Escherichia coli, GI1786409, Length=166, Percent_Identity=28.3132530120482, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO3_CLOPE (Q8XJR3)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_562607.1
- ProteinModelPortal:   Q8XJR3
- GeneID:   990001
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE1691
- NMPDR:   fig|195102.1.peg.1754
- HOGENOM:   HBG617116
- OMA:   WKTTHFD
- PhylomeDB:   Q8XJR3
- ProtClustDB:   PRK00448
- BioCyc:   CPER195102:CPE1691-MONOMER
- BRENDA:   2.7.7.7
- GO:   GO:0005737
- HAMAP:   MF_00356
- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337
- SMART:   SM00479
- SMART:   SM00481
- TIGRFAMs:   TIGR00573
- TIGRFAMs:   TIGR01405

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; SSF50249 Nucleic_acid_OB; SSF53098 RNaseH_fold

EC number: =2.7.7.7

Molecular weight: Translated: 163630; Mature: 163498

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNEFVKQINRSIKSDDNLNDLEFEITKFQLLKKSNTLRTIIKSKDQLSEEQKKIIKQYI
CCHHHHHHHHHHHCCCCCCCCHHEEHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHH
KKAIGFEINIEIMYYIDISDITLKQVVDQHWNHVCEKIIEKHPVLKEVLLNSPIVIEGEK
HHHCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEECCE
IIIKNGSEFLCTFVNKKHIDREIKGYIKSFFGINSLVEVKYDESLANKNYNDEKLNENKE
EEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCCCHHHCCCCHH
IAKKVIETMKAQAAQEKPVKKESSDNKHKSNGGNKGGYEKKSYKDEPKNENTILGRNIQG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
DTIDISSIDMGSGIVTISGDVFKTDIFETKTGRIILTFFITDYTSSIAVKCFLRDKDKEH
CEEEEEEEECCCCEEEEECCEEEEHHEECCCCCEEEEEEEECCCCCEEEEEEECCCCHHH
VLENVKKGLYCKVRGEATMDPYAKEVVIMARDINKLTKIERMDTAEEKRVELHMHTTMSS
HHHHHHCCCEEEEECCCCCCCHHHHHEEEHHHHHHHHHHHHHCCCHHHHEEEEEHHHHHH
MDAVTAASKIVERAAKFGHKAVAITDHGVVQAFPDAQIAAKKNNIKVIYGVEGYLADNGT
HHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCEEECCCCEEEEEECCEEEECCCC
PIVINGHEESFDDEYVVFDIETTGFSSKNDKIIEIGAVKLKDGEIVDSFSTFVDPKVNIP
EEEEECCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCC
YKITELTSITQNMVNGQPTIDEVLPKFMEFVGNSVLVAHNAAFDVGFIKKNLMDMGKTLK
EEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
NPVMDTVPLARYLYPDLKKVKLNLVAKHLGISLENHHRAVDDAKATAEILKFSFKKMKEE
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHH
MDIHDVKTLNEKYLSNIDVKKLPLHHIIILAKNQTGIKNLYKLVSMAHLDYFARRPRLPK
CCHHHHHHHHHHHHCCCCCEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCH
SIITEYREGLIIGSACEAGQLYKAVLEGKTDGELKEIASFYDYLEIQPIQNNEFLIRKGN
HHHHHHHCCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEECCCCCEEEEECC
VKDEEELRELNRKIYDLGKEMDKPVVATCDCHFLDPNDEVFRRIIMAGQGYGDADNQPPL
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCE
YFRTTNEMMKEFEYLGEEACREVVIENTQKIADMVEAVKPIPDETFPPKIEGAEEEIRNM
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
TMNKVHSIYGENLPEVVQKRLDKELNSIINNGYAVLYLIAQKLVAKSLEDGYLVGSRGSV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCC
GSSFVATMSDITEVNGLPPHYVCPNCKKSEFFLDGSISSGADLPDKNCPDCGAKYIKDGH
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHCCCC
DIPFETFLGFEGDKEPDIDLNFSGEYQAVVHKYTEVLFGKGYVFKAGTIGTVAEKTAYGF
CCCHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHH
VKKYLQERGLVVSQAEIERLTIGCTGIKRTSGQHPGGIMVVPNDNEIYNFCPIQHPADDV
HHHHHHHCCCEEEECHHEEEEEEECCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCC
NTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTGLDPKTIPLNDPKVISLFTSP
CCCEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEECCCCCCEEEEEECC
DALGVTKEELGCEVGSYGLPEFGTKFVRQMLVDTQPKSFADLVRISGLSHGTDVWLNNAQ
CCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEECCCH
YFIKEGYTTLKDCIATRDDIMVYLMYKDLPPKTAFTIMEKVRKGKGLSEEDEALMREKNV
HHHHCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PDWYIESCKRIKYMFPKGHAVAYVMMAVRIAYYKVYYPEAYYTTYFTVRADDFDADLICK
CHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHEECCCEEEEEEEEEEECCCCCCEEEC
GEEAIKAKMEELNSLGNNISVKEKGLLTILEISYEMYKRGLNFLKVDLYKSEATKFKIEE
CHHHHHHHHHHHHHCCCCCEECCCCCEEHHHHHHHHHHCCCCEEEEEEEECCCCEEEECC
DGIRPPLNALQGVGDNAAKSIVECRVNGEFISKEDLRLRSKVSKTVIETLDNHGCLEGMQ
CCCCCCHHHHHCCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHC
ESNQLSLFG
CCCCEECCC
>Mature Secondary Structure 
SNEFVKQINRSIKSDDNLNDLEFEITKFQLLKKSNTLRTIIKSKDQLSEEQKKIIKQYI
CHHHHHHHHHHHCCCCCCCCHHEEHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHH
KKAIGFEINIEIMYYIDISDITLKQVVDQHWNHVCEKIIEKHPVLKEVLLNSPIVIEGEK
HHHCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEECCE
IIIKNGSEFLCTFVNKKHIDREIKGYIKSFFGINSLVEVKYDESLANKNYNDEKLNENKE
EEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCCCHHHCCCCHH
IAKKVIETMKAQAAQEKPVKKESSDNKHKSNGGNKGGYEKKSYKDEPKNENTILGRNIQG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
DTIDISSIDMGSGIVTISGDVFKTDIFETKTGRIILTFFITDYTSSIAVKCFLRDKDKEH
CEEEEEEEECCCCEEEEECCEEEEHHEECCCCCEEEEEEEECCCCCEEEEEEECCCCHHH
VLENVKKGLYCKVRGEATMDPYAKEVVIMARDINKLTKIERMDTAEEKRVELHMHTTMSS
HHHHHHCCCEEEEECCCCCCCHHHHHEEEHHHHHHHHHHHHHCCCHHHHEEEEEHHHHHH
MDAVTAASKIVERAAKFGHKAVAITDHGVVQAFPDAQIAAKKNNIKVIYGVEGYLADNGT
HHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCEEECCCCEEEEEECCEEEECCCC
PIVINGHEESFDDEYVVFDIETTGFSSKNDKIIEIGAVKLKDGEIVDSFSTFVDPKVNIP
EEEEECCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCC
YKITELTSITQNMVNGQPTIDEVLPKFMEFVGNSVLVAHNAAFDVGFIKKNLMDMGKTLK
EEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
NPVMDTVPLARYLYPDLKKVKLNLVAKHLGISLENHHRAVDDAKATAEILKFSFKKMKEE
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHH
MDIHDVKTLNEKYLSNIDVKKLPLHHIIILAKNQTGIKNLYKLVSMAHLDYFARRPRLPK
CCHHHHHHHHHHHHCCCCCEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCH
SIITEYREGLIIGSACEAGQLYKAVLEGKTDGELKEIASFYDYLEIQPIQNNEFLIRKGN
HHHHHHHCCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEECCCCCEEEEECC
VKDEEELRELNRKIYDLGKEMDKPVVATCDCHFLDPNDEVFRRIIMAGQGYGDADNQPPL
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCE
YFRTTNEMMKEFEYLGEEACREVVIENTQKIADMVEAVKPIPDETFPPKIEGAEEEIRNM
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
TMNKVHSIYGENLPEVVQKRLDKELNSIINNGYAVLYLIAQKLVAKSLEDGYLVGSRGSV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCC
GSSFVATMSDITEVNGLPPHYVCPNCKKSEFFLDGSISSGADLPDKNCPDCGAKYIKDGH
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHCCCC
DIPFETFLGFEGDKEPDIDLNFSGEYQAVVHKYTEVLFGKGYVFKAGTIGTVAEKTAYGF
CCCHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHH
VKKYLQERGLVVSQAEIERLTIGCTGIKRTSGQHPGGIMVVPNDNEIYNFCPIQHPADDV
HHHHHHHCCCEEEECHHEEEEEEECCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCC
NTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTGLDPKTIPLNDPKVISLFTSP
CCCEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEECCCCCCEEEEEECC
DALGVTKEELGCEVGSYGLPEFGTKFVRQMLVDTQPKSFADLVRISGLSHGTDVWLNNAQ
CCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEECCCH
YFIKEGYTTLKDCIATRDDIMVYLMYKDLPPKTAFTIMEKVRKGKGLSEEDEALMREKNV
HHHHCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PDWYIESCKRIKYMFPKGHAVAYVMMAVRIAYYKVYYPEAYYTTYFTVRADDFDADLICK
CHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHEECCCEEEEEEEEEEECCCCCCEEEC
GEEAIKAKMEELNSLGNNISVKEKGLLTILEISYEMYKRGLNFLKVDLYKSEATKFKIEE
CHHHHHHHHHHHHHCCCCCEECCCCCEEHHHHHHHHHHCCCCEEEEEEEECCCCEEEECC
DGIRPPLNALQGVGDNAAKSIVECRVNGEFISKEDLRLRSKVSKTVIETLDNHGCLEGMQ
CCCCCCHHHHHCCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHC
ESNQLSLFG
CCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842