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The map label for this gene is mprF [H]

Identifier: 18310575

GI number: 18310575

Start: 1867256

End: 1868683

Strand: Reverse

Name: mprF [H]

Synonym: CPE1593

Alternate gene names: 18310575

Gene position: 1868683-1867256 (Counterclockwise)

Preceding gene: 18310576

Following gene: 18310574

Centisome position: 61.64

GC content: 28.43

Gene sequence:

>1428_bases
ATGTTAATAATGACCTCTAAGGAAGTTTTCTTTAAGGTAAAAAGAGCTTATTATGTTACATTAACATTGCTTATAGTAGG
AGGAGCCTTTGCCTTTGTAAAAGATTTAGATTACAAAGAAGGAATTTTTATTTTAGGAGTAATAATACTTCTAATATTAT
CAAAAAAGAGTTTTTACAGAAAAAGTATCCCTATTAAGGTTACTAAATTAAGTGGTATATTATTAGTTCTTTCAATTGTA
ATGATTATCTTTGCAAGTTTTATACATAAATTTAACATACATTTTAGTAAGAATTATAGGTACTATGTAGACTTTTTCCA
TAGCACAAAGGGGTATTTAAGAATAGCATTATTCACTTATATAGCCTTTATAATATTTGTGATAATATGGTATTTAACAA
TGCCTAAAATAGAAGATGACGAAAGGTATATGGATGCTGATTTAGAAAAGGTATCAAAATTCTTTAAAGAAATAGATTAT
GGAACAATATTCTCCCATTTAGTTTATTTAAAGGATAAAAAGGTCTTTTGGGCTAATGAAGGAGAGTCCTTAATAATGTA
CAGCAAGTACAAAGATAAGATAATAGTTTTAGGAGATCCTATAGCCACTAAGGAAAATCTATATAGTTGTATAGAAGAGT
TTCAAGCTTTTACAAATTTATATGGATATGATGTTGTTTTTTATGAAATAGAAGAAAAAAACTTTTCTACCTATCATGAT
GCAGGTTATTATTTCTTTAAGTTAGGAGAAGAGGCAAGAATAGATTTAGAAGAATTTAATTTGATTGGTTCTAAAAAGAG
TGCCTTTAGAAATACCTTAAGAAGAGTTGAAAGGGAAGGATATAGTTTTAGTATTATAGAGCCTCCTTTTAATAATGAGG
TAGTAAGTCAATTGAAGGAAATATCCGATAAATGGCTAGGGGCCAGAAAGGAAAAGGGATTTTCTCTAGGATGGTTTAGT
GAGGATTATATACAAAGATCGCCTATAGCTATTTTAAAGAATGAAGAAGAAAATAAGATTATGGGCTTTGTAACAATAAT
GGATGCTAATGATGGAGGGGAGACAGTAGCAATAGATTTAATGAGAATAGATAAAAATGCTCCTAATGCCTCTATGGATT
ACTTAATGCTTAATTTATTCTTAACATTTAAAGAAAAAGGATATAAATATTTTAGCTTAGGAGAAGCACCATTATCTAAT
GTAGGATTTAACACTCATTCACATTTACAAGAAAAGCTTGCAAGATTAGTTTATAATAGCGGTAATATATTCTATAGTTT
TGATGGACTAAGAAGATATAAGTCAAAGTTTTCTCCAATTTGGCAGCCTAGATATTTAGCATACCCTAAGTTTATGTCAT
TACCAGAGGTGTTTATTAACTTATGTTTATTAATAGCCAATTCAAAGGAAAGAGTAGAGAAAAAATAA

Upstream 100 bases:

>100_bases
GATTTATCCTAGTATATTTTATAAGATAAAATTTTTAGACAATATATATAGTTTATCTTTTTTAAGGTTTTCACATAGAG
CTTCAGTATTAATTGGATTA

Downstream 100 bases:

>100_bases
AAACGTATATTTTAAGTTAAGTTTGATTTAAAATTAAATCTTTATATCTAGCTTAATTAAGTTTATTATGTTAAAGGGAG
TCTTTTAGTTATAAGGCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MLIMTSKEVFFKVKRAYYVTLTLLIVGGAFAFVKDLDYKEGIFILGVIILLILSKKSFYRKSIPIKVTKLSGILLVLSIV
MIIFASFIHKFNIHFSKNYRYYVDFFHSTKGYLRIALFTYIAFIIFVIIWYLTMPKIEDDERYMDADLEKVSKFFKEIDY
GTIFSHLVYLKDKKVFWANEGESLIMYSKYKDKIIVLGDPIATKENLYSCIEEFQAFTNLYGYDVVFYEIEEKNFSTYHD
AGYYFFKLGEEARIDLEEFNLIGSKKSAFRNTLRRVEREGYSFSIIEPPFNNEVVSQLKEISDKWLGARKEKGFSLGWFS
EDYIQRSPIAILKNEEENKIMGFVTIMDANDGGETVAIDLMRIDKNAPNASMDYLMLNLFLTFKEKGYKYFSLGEAPLSN
VGFNTHSHLQEKLARLVYNSGNIFYSFDGLRRYKSKFSPIWQPRYLAYPKFMSLPEVFINLCLLIANSKERVEKK

Sequences:

>Translated_475_residues
MLIMTSKEVFFKVKRAYYVTLTLLIVGGAFAFVKDLDYKEGIFILGVIILLILSKKSFYRKSIPIKVTKLSGILLVLSIV
MIIFASFIHKFNIHFSKNYRYYVDFFHSTKGYLRIALFTYIAFIIFVIIWYLTMPKIEDDERYMDADLEKVSKFFKEIDY
GTIFSHLVYLKDKKVFWANEGESLIMYSKYKDKIIVLGDPIATKENLYSCIEEFQAFTNLYGYDVVFYEIEEKNFSTYHD
AGYYFFKLGEEARIDLEEFNLIGSKKSAFRNTLRRVEREGYSFSIIEPPFNNEVVSQLKEISDKWLGARKEKGFSLGWFS
EDYIQRSPIAILKNEEENKIMGFVTIMDANDGGETVAIDLMRIDKNAPNASMDYLMLNLFLTFKEKGYKYFSLGEAPLSN
VGFNTHSHLQEKLARLVYNSGNIFYSFDGLRRYKSKFSPIWQPRYLAYPKFMSLPEVFINLCLLIANSKERVEKK
>Mature_475_residues
MLIMTSKEVFFKVKRAYYVTLTLLIVGGAFAFVKDLDYKEGIFILGVIILLILSKKSFYRKSIPIKVTKLSGILLVLSIV
MIIFASFIHKFNIHFSKNYRYYVDFFHSTKGYLRIALFTYIAFIIFVIIWYLTMPKIEDDERYMDADLEKVSKFFKEIDY
GTIFSHLVYLKDKKVFWANEGESLIMYSKYKDKIIVLGDPIATKENLYSCIEEFQAFTNLYGYDVVFYEIEEKNFSTYHD
AGYYFFKLGEEARIDLEEFNLIGSKKSAFRNTLRRVEREGYSFSIIEPPFNNEVVSQLKEISDKWLGARKEKGFSLGWFS
EDYIQRSPIAILKNEEENKIMGFVTIMDANDGGETVAIDLMRIDKNAPNASMDYLMLNLFLTFKEKGYKYFSLGEAPLSN
VGFNTHSHLQEKLARLVYNSGNIFYSFDGLRRYKSKFSPIWQPRYLAYPKFMSLPEVFINLCLLIANSKERVEKK

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contribu

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 55633; Mature: 55633

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIMTSKEVFFKVKRAYYVTLTLLIVGGAFAFVKDLDYKEGIFILGVIILLILSKKSFYR
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHH
KSIPIKVTKLSGILLVLSIVMIIFASFIHKFNIHFSKNYRYYVDFFHSTKGYLRIALFTY
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEEEEECCCCHHHHHHHHH
IAFIIFVIIWYLTMPKIEDDERYMDADLEKVSKFFKEIDYGTIFSHLVYLKDKKVFWANE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCEEEEECC
GESLIMYSKYKDKIIVLGDPIATKENLYSCIEEFQAFTNLYGYDVVFYEIEEKNFSTYHD
CCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEC
AGYYFFKLGEEARIDLEEFNLIGSKKSAFRNTLRRVEREGYSFSIIEPPFNNEVVSQLKE
CCEEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHH
ISDKWLGARKEKGFSLGWFSEDYIQRSPIAILKNEEENKIMGFVTIMDANDGGETVAIDL
HHHHHCCCHHCCCCEECCCCHHHHCCCCEEEEECCCCCEEEEEEEEEECCCCCCEEEEEE
MRIDKNAPNASMDYLMLNLFLTFKEKGYKYFSLGEAPLSNVGFNTHSHLQEKLARLVYNS
EEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
GNIFYSFDGLRRYKSKFSPIWQPRYLAYPKFMSLPEVFINLCLLIANSKERVEKK
CCEEEEEHHHHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure
MLIMTSKEVFFKVKRAYYVTLTLLIVGGAFAFVKDLDYKEGIFILGVIILLILSKKSFYR
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHH
KSIPIKVTKLSGILLVLSIVMIIFASFIHKFNIHFSKNYRYYVDFFHSTKGYLRIALFTY
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEEEEECCCCHHHHHHHHH
IAFIIFVIIWYLTMPKIEDDERYMDADLEKVSKFFKEIDYGTIFSHLVYLKDKKVFWANE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCEEEEECC
GESLIMYSKYKDKIIVLGDPIATKENLYSCIEEFQAFTNLYGYDVVFYEIEEKNFSTYHD
CCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEC
AGYYFFKLGEEARIDLEEFNLIGSKKSAFRNTLRRVEREGYSFSIIEPPFNNEVVSQLKE
CCEEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHH
ISDKWLGARKEKGFSLGWFSEDYIQRSPIAILKNEEENKIMGFVTIMDANDGGETVAIDL
HHHHHCCCHHCCCCEECCCCHHHHCCCCEEEEECCCCCEEEEEEEEEECCCCCCEEEEEE
MRIDKNAPNASMDYLMLNLFLTFKEKGYKYFSLGEAPLSNVGFNTHSHLQEKLARLVYNS
EEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
GNIFYSFDGLRRYKSKFSPIWQPRYLAYPKFMSLPEVFINLCLLIANSKERVEKK
CCEEEEEHHHHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]