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The map label for this gene is ttcA [H]

Identifier: 18310476

GI number: 18310476

Start: 1747023

End: 1747856

Strand: Reverse

Name: ttcA [H]

Synonym: CPE1494

Alternate gene names: 18310476

Gene position: 1747856-1747023 (Counterclockwise)

Preceding gene: 18310477

Following gene: 18310475

Centisome position: 57.66

GC content: 29.26

Gene sequence:

>834_bases
ATGGCAAAGCTTTTTCAAGAGTTAAAAAAACATGGTCAAATAAACTTTGAACTTGTATTTTTAGCTATGGATCCAGGATA
TCATCCTCAAATTAGAGAGTTACTTGAGGATAATTGTAAATACTTAGATATACCAGTACATATTTATGATTCAGGAATAT
TCCAAGTTGTAGACAAAATAGCTAAGGACTATCCATGTTATATGTGTGCAAGAATGAGAAGAGGATCATTATATGGTAAG
GCAAAGGAACTTGGATGTAATAAGTTAGCCTTAGGACATCACTTTAATGATGTTATAGAAACAACAATGCTTAATGTTTT
ATATGCAGGTAACTTTAAAACCATGTTACCAAAATTAAAAGCTGCTAATTTTGATGGAATAGAGCTTATAAGACCTCTAT
ATTATATAGAAGAAAAATATATAAAAAGATGGATTCAAAGAGCTGGAATATGGCCATTAAACTGTGCATGTATGGTAGCT
GCTAAAAAAATAGGTAATAAGCGTTTTGAAATTAAAGATATGATTGAAGAGTTTAAAGAAAAGTTTGATGGAGTAGATAA
ATCAATATTTAGAGCAGCACAAAATGTAAGTGTAGATTCTATTTTAGGATGGGATATTGATGGAGAACATTATTCTTATT
TAGACTTTTATGATGAAGAATCCTTATTAAATTCAACGGCTGAGTTAAAGCAAAAAGGATTAGTAAATGAAGCTGTTGCC
TATGAAAGACAAAACATAGCTAGAAATCTTATAGGACTATTAGATGATGAAGTAATAGCTGAGAAAACAGGATTATCTTT
AAAAGAAATAAAAAGTATGCAAATAGATAATTAA

Upstream 100 bases:

>100_bases
GTTTGGTCAAAATTTATAAAAGCTATAAAGGATTATAAATTAGTAGAAGAAGGGGATAAGATTAGCTATTGCTATTTCAG
GAGGAAAAGATTCTTTAATA

Downstream 100 bases:

>100_bases
AAAATGGGATGTATTAAGACAAAAAGATAAAACTTATAAATGAGTTTTTACAATTATTAAATTTATAATTGTAAAATTAT
AATAGGTTATATTATAAAGC

Product: PP-loop family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MAKLFQELKKHGQINFELVFLAMDPGYHPQIRELLEDNCKYLDIPVHIYDSGIFQVVDKIAKDYPCYMCARMRRGSLYGK
AKELGCNKLALGHHFNDVIETTMLNVLYAGNFKTMLPKLKAANFDGIELIRPLYYIEEKYIKRWIQRAGIWPLNCACMVA
AKKIGNKRFEIKDMIEEFKEKFDGVDKSIFRAAQNVSVDSILGWDIDGEHYSYLDFYDEESLLNSTAELKQKGLVNEAVA
YERQNIARNLIGLLDDEVIAEKTGLSLKEIKSMQIDN

Sequences:

>Translated_277_residues
MAKLFQELKKHGQINFELVFLAMDPGYHPQIRELLEDNCKYLDIPVHIYDSGIFQVVDKIAKDYPCYMCARMRRGSLYGK
AKELGCNKLALGHHFNDVIETTMLNVLYAGNFKTMLPKLKAANFDGIELIRPLYYIEEKYIKRWIQRAGIWPLNCACMVA
AKKIGNKRFEIKDMIEEFKEKFDGVDKSIFRAAQNVSVDSILGWDIDGEHYSYLDFYDEESLLNSTAELKQKGLVNEAVA
YERQNIARNLIGLLDDEVIAEKTGLSLKEIKSMQIDN
>Mature_276_residues
AKLFQELKKHGQINFELVFLAMDPGYHPQIRELLEDNCKYLDIPVHIYDSGIFQVVDKIAKDYPCYMCARMRRGSLYGKA
KELGCNKLALGHHFNDVIETTMLNVLYAGNFKTMLPKLKAANFDGIELIRPLYYIEEKYIKRWIQRAGIWPLNCACMVAA
KKIGNKRFEIKDMIEEFKEKFDGVDKSIFRAAQNVSVDSILGWDIDGEHYSYLDFYDEESLLNSTAELKQKGLVNEAVAY
ERQNIARNLIGLLDDEVIAEKTGLSLKEIKSMQIDN

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=201, Percent_Identity=33.8308457711443, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 31926; Mature: 31795

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLFQELKKHGQINFELVFLAMDPGYHPQIRELLEDNCKYLDIPVHIYDSGIFQVVDKI
CHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHH
AKDYPCYMCARMRRGSLYGKAKELGCNKLALGHHFNDVIETTMLNVLYAGNFKTMLPKLK
HHCCCHHHHHHHHHCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AANFDGIELIRPLYYIEEKYIKRWIQRAGIWPLNCACMVAAKKIGNKRFEIKDMIEEFKE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
KFDGVDKSIFRAAQNVSVDSILGWDIDGEHYSYLDFYDEESLLNSTAELKQKGLVNEAVA
HHCCCCHHHHHHHHCCCHHHEECCCCCCCCEEHHHHCCHHHHHHHHHHHHHHCCHHHHHH
YERQNIARNLIGLLDDEVIAEKTGLSLKEIKSMQIDN
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
>Mature Secondary Structure 
AKLFQELKKHGQINFELVFLAMDPGYHPQIRELLEDNCKYLDIPVHIYDSGIFQVVDKI
HHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHH
AKDYPCYMCARMRRGSLYGKAKELGCNKLALGHHFNDVIETTMLNVLYAGNFKTMLPKLK
HHCCCHHHHHHHHHCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AANFDGIELIRPLYYIEEKYIKRWIQRAGIWPLNCACMVAAKKIGNKRFEIKDMIEEFKE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
KFDGVDKSIFRAAQNVSVDSILGWDIDGEHYSYLDFYDEESLLNSTAELKQKGLVNEAVA
HHCCCCHHHHHHHHCCCHHHEECCCCCCCCEEHHHHCCHHHHHHHHHHHHHHCCHHHHHH
YERQNIARNLIGLLDDEVIAEKTGLSLKEIKSMQIDN
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA