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The map label for this gene is gluP [H]

Identifier: 18310434

GI number: 18310434

Start: 1709642

End: 1710670

Strand: Reverse

Name: gluP [H]

Synonym: CPE1452

Alternate gene names: 18310434

Gene position: 1710670-1709642 (Counterclockwise)

Preceding gene: 18310435

Following gene: 18310433

Centisome position: 56.43

GC content: 28.18

Gene sequence:

>1029_bases
ATGAGTAAATTTGAGCAAGATTATTTCAACTTACTTATAAATAATTATGGTTTTTATGTAGAAGACTTAAAAGGAGAACA
GGATAAAGAACTATGGATAGCTTTAAAGACAGTTAAAGATGATGGAAAATATGCAGTTATAATATCTAAGTCTTATGAAG
AGGAAGAAAATTTAAAAATTGCAGAAGATTATTTAAAAAGCTTAGGTAAGTCATATTCTCTTCATAATATAATTCTTTAT
AAAAGCTATGATAGGGATGAAAAAAAGGATGAAGACTTTTCTATAGATGAGAATTGTCATAGAGTAATTGTTGATGTTCA
GAAAAGAGAAGTTTTAAAAAGTGATAGGAGCTCTGAGCCTCTAGCAAAAATATTAGAATTTTTATTAAAAAAGAAAGAAG
AACCAAAAGTTCCTTGGTATAAAAGATTAAGATGTGGAAAAGTTACAGGAATATTGATTGGTTTAAATATTTTAGCTTTT
CTAGTTTGTCTTATTGTAGCTACTGCTTTAGGTGCTGGATTCTTCAGAAATATAGTAGAGATGAATCCACAAATTCTATA
TTGGATGGGTGCTAAGCATAATAATGCAATAATATTCCATGGAGAATATTATAGATTAGTAACTTCTATGTTTTTGCATG
GTGGAATAGTACATCTTTTATTTAATATGTATGCTCTATATATATTAGGAGATTTCATAGAAAGGATTTATGGAGCGAAA
AAATATTTAGCTATCTATTTTGTTTCAGGAATAGTAGCAAGTATATTTAGCTTATACTTTTCACCAGTTATGGGAGTTGG
CGCTTCAGGAGCTATATTTGGACTTTTAGGGGCAGCTTTAGTTTTTGCTTATAATGAAAAAGATAGAATTGGTAAAGCCT
TAGTAACTAATATAATAGTTATTATATTGCTTAATGTATTTATCGGTCTATCAATGTCTAATATAGATATATCTGCTCGT
TTTGGCGGATTCATAGCAGGAGCTATTTTAGGACTTTTCTTCCATAATTATAAAATAATAAGAAAATAA

Upstream 100 bases:

>100_bases
TAGATATGACAACATCTAAGCCTCTTAAAGATACCTTAGATAGATTTAATGAGCTTTTAGATATGTTGGAAGAAATTATT
TAGAAGATTGAGGAGAGGCA

Downstream 100 bases:

>100_bases
AAAAATTCCTCTGTTTTAAATAAGGCAGAGGAGTTTTTTTACCTTCAAAATTAAGAATAAATACTATATACTAAAAGATG
GATAATTATTAAATAATAAG

Product: rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSKFEQDYFNLLINNYGFYVEDLKGEQDKELWIALKTVKDDGKYAVIISKSYEEEENLKIAEDYLKSLGKSYSLHNIILY
KSYDRDEKKDEDFSIDENCHRVIVDVQKREVLKSDRSSEPLAKILEFLLKKKEEPKVPWYKRLRCGKVTGILIGLNILAF
LVCLIVATALGAGFFRNIVEMNPQILYWMGAKHNNAIIFHGEYYRLVTSMFLHGGIVHLLFNMYALYILGDFIERIYGAK
KYLAIYFVSGIVASIFSLYFSPVMGVGASGAIFGLLGAALVFAYNEKDRIGKALVTNIIVIILLNVFIGLSMSNIDISAR
FGGFIAGAILGLFFHNYKIIRK

Sequences:

>Translated_342_residues
MSKFEQDYFNLLINNYGFYVEDLKGEQDKELWIALKTVKDDGKYAVIISKSYEEEENLKIAEDYLKSLGKSYSLHNIILY
KSYDRDEKKDEDFSIDENCHRVIVDVQKREVLKSDRSSEPLAKILEFLLKKKEEPKVPWYKRLRCGKVTGILIGLNILAF
LVCLIVATALGAGFFRNIVEMNPQILYWMGAKHNNAIIFHGEYYRLVTSMFLHGGIVHLLFNMYALYILGDFIERIYGAK
KYLAIYFVSGIVASIFSLYFSPVMGVGASGAIFGLLGAALVFAYNEKDRIGKALVTNIIVIILLNVFIGLSMSNIDISAR
FGGFIAGAILGLFFHNYKIIRK
>Mature_341_residues
SKFEQDYFNLLINNYGFYVEDLKGEQDKELWIALKTVKDDGKYAVIISKSYEEEENLKIAEDYLKSLGKSYSLHNIILYK
SYDRDEKKDEDFSIDENCHRVIVDVQKREVLKSDRSSEPLAKILEFLLKKKEEPKVPWYKRLRCGKVTGILIGLNILAFL
VCLIVATALGAGFFRNIVEMNPQILYWMGAKHNNAIIFHGEYYRLVTSMFLHGGIVHLLFNMYALYILGDFIERIYGAKK
YLAIYFVSGIVASIFSLYFSPVMGVGASGAIFGLLGAALVFAYNEKDRIGKALVTNIIVIILLNVFIGLSMSNIDISARF
GGFIAGAILGLFFHNYKIIRK

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 38941; Mature: 38810

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFEQDYFNLLINNYGFYVEDLKGEQDKELWIALKTVKDDGKYAVIISKSYEEEENLKI
CCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCCH
AEDYLKSLGKSYSLHNIILYKSYDRDEKKDEDFSIDENCHRVIVDVQKREVLKSDRSSEP
HHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCH
LAKILEFLLKKKEEPKVPWYKRLRCGKVTGILIGLNILAFLVCLIVATALGAGFFRNIVE
HHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNPQILYWMGAKHNNAIIFHGEYYRLVTSMFLHGGIVHLLFNMYALYILGDFIERIYGAK
CCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHH
KYLAIYFVSGIVASIFSLYFSPVMGVGASGAIFGLLGAALVFAYNEKDRIGKALVTNIIV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IILLNVFIGLSMSNIDISARFGGFIAGAILGLFFHNYKIIRK
HHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
SKFEQDYFNLLINNYGFYVEDLKGEQDKELWIALKTVKDDGKYAVIISKSYEEEENLKI
CCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCCH
AEDYLKSLGKSYSLHNIILYKSYDRDEKKDEDFSIDENCHRVIVDVQKREVLKSDRSSEP
HHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCH
LAKILEFLLKKKEEPKVPWYKRLRCGKVTGILIGLNILAFLVCLIVATALGAGFFRNIVE
HHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNPQILYWMGAKHNNAIIFHGEYYRLVTSMFLHGGIVHLLFNMYALYILGDFIERIYGAK
CCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHH
KYLAIYFVSGIVASIFSLYFSPVMGVGASGAIFGLLGAALVFAYNEKDRIGKALVTNIIV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IILLNVFIGLSMSNIDISARFGGFIAGAILGLFFHNYKIIRK
HHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]