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The map label for this gene is xerC [H]

Identifier: 18310145

GI number: 18310145

Start: 1361032

End: 1362384

Strand: Reverse

Name: xerC [H]

Synonym: CPE1163

Alternate gene names: 18310145

Gene position: 1362384-1361032 (Counterclockwise)

Preceding gene: 18310146

Following gene: 18310143

Centisome position: 44.94

GC content: 25.57

Gene sequence:

>1353_bases
ATGAATAATGAAGCGAATCAATTCGAAAATTTTAAATACTCACAAGAAATCAAAGAATTACTGAATATAAATTTAAGTAA
TGATGACTTAAATAATCTTGATCACATATATAACTATTACGATTCTCAAAATATCCAGCGTGACTATGAAGATTTAATTG
AAGATATTTATATTTTTATTTTTAAAAGAAAGCTTAGTATTACACAACTGGCAGAGATCTATAAAGTTAATCAAAGAATC
ATTAAACGCTGGTTAAAAGAACTTGGAATGGACAAGCTTTTAGAAGTAGAAAAAGGTGGCGATTCTGTTGAAAAATCAAA
TTTTAAAAACAGCAAACAAGATGAATTACTCGAAAAGAATAAATTAAAATTTGATTTTTTAGAGAAATCGAAGCATCCAA
AAAGAGTTATTGAATTCTTAAACTACTTAGAAAATGTAAAAGGAAAATCCCTAAACACCGTAAAAGGATATTCAGTTGAT
TTAGGATTATTTTTTAAATTTTTGAAAGTCTATAAAGGTCTAGAAAATAATATTGAATTAGAAAAAATTGAAGAAGTTGA
AATTTCTGATTTAGGTGATAATTTTATAAAGGATATAACACTATCTGATATCTATGCATTTTTAGCTTTTTTAGAAAAAG
TTAGAAACAATAGCGCTTATGCCAGAGCTAGAAAAGTTGCTACTTTAAAATCTTTCTTTAAGTTTTTAAATTCTAAAATA
AAACTAATAGATGAAAACCCTACAGTAGAATTAGAATCTCCAAAGATAAATAAAAGACACCCAGTTTATTTAACCTTAGA
TCAAAGTATAACTGTTTTAAACTCTATGGATAAAGGAAATAAAAATTATTATAGAGATTATTGTATACTAACTTTATTTT
TAAACTGCGGAATGAGACTATCTGAACTTTGTAATATTGAAATAGAAAAAATCAAGGGAGATACCTTAACTATTATAGGT
AAAGGAAATAAAGAAAGAACTGTTTATTTAAACGAAGCTTCAATTGCAGCTATAGAAAACTATTTGAAAAATAGAAATGA
TTCAAAAGCTACTGAAGAAGCTAAAAAATACTTATTTTTATCAAGTAAATATAGACCTATAAACAAAAGAAGTGTTGAAA
TTTTAGTAAAAAAACATATAGAAAATGCAGGATTTAAAGATCAAAAATATACACCACATAAACTTAGACACACAGCTGCC
ACACTTATGTATAAGTATGGTAATGTAGATATAAGAAGCTTGCAAAATATATTAGGCCACGAAAATATTTCAACAACCCA
AATATATACCCATGTAGATGATGAAACTTTAAGAGAAGCTGTTAAAACTAATCCTTTAGCAAATATAAAATAG

Upstream 100 bases:

>100_bases
TTTATAACTTCGCTAAATATACATTTAGCGAAGTTGTTGTGTTTTTTGATAAAATATGCTACAATATAGTTATATCAAGG
CTTTGAAAGGATTTTAGACT

Downstream 100 bases:

>100_bases
CATCACTTCTTGATTTTATGAAGAAAATACGAGGATAGAACATATGTTCTATCCTCGTATTTTTAGCACTTTTATATAAG
AAACACTCTTCTACTTTTCT

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNNEANQFENFKYSQEIKELLNINLSNDDLNNLDHIYNYYDSQNIQRDYEDLIEDIYIFIFKRKLSITQLAEIYKVNQRI
IKRWLKELGMDKLLEVEKGGDSVEKSNFKNSKQDELLEKNKLKFDFLEKSKHPKRVIEFLNYLENVKGKSLNTVKGYSVD
LGLFFKFLKVYKGLENNIELEKIEEVEISDLGDNFIKDITLSDIYAFLAFLEKVRNNSAYARARKVATLKSFFKFLNSKI
KLIDENPTVELESPKINKRHPVYLTLDQSITVLNSMDKGNKNYYRDYCILTLFLNCGMRLSELCNIEIEKIKGDTLTIIG
KGNKERTVYLNEASIAAIENYLKNRNDSKATEEAKKYLFLSSKYRPINKRSVEILVKKHIENAGFKDQKYTPHKLRHTAA
TLMYKYGNVDIRSLQNILGHENISTTQIYTHVDDETLREAVKTNPLANIK

Sequences:

>Translated_450_residues
MNNEANQFENFKYSQEIKELLNINLSNDDLNNLDHIYNYYDSQNIQRDYEDLIEDIYIFIFKRKLSITQLAEIYKVNQRI
IKRWLKELGMDKLLEVEKGGDSVEKSNFKNSKQDELLEKNKLKFDFLEKSKHPKRVIEFLNYLENVKGKSLNTVKGYSVD
LGLFFKFLKVYKGLENNIELEKIEEVEISDLGDNFIKDITLSDIYAFLAFLEKVRNNSAYARARKVATLKSFFKFLNSKI
KLIDENPTVELESPKINKRHPVYLTLDQSITVLNSMDKGNKNYYRDYCILTLFLNCGMRLSELCNIEIEKIKGDTLTIIG
KGNKERTVYLNEASIAAIENYLKNRNDSKATEEAKKYLFLSSKYRPINKRSVEILVKKHIENAGFKDQKYTPHKLRHTAA
TLMYKYGNVDIRSLQNILGHENISTTQIYTHVDDETLREAVKTNPLANIK
>Mature_450_residues
MNNEANQFENFKYSQEIKELLNINLSNDDLNNLDHIYNYYDSQNIQRDYEDLIEDIYIFIFKRKLSITQLAEIYKVNQRI
IKRWLKELGMDKLLEVEKGGDSVEKSNFKNSKQDELLEKNKLKFDFLEKSKHPKRVIEFLNYLENVKGKSLNTVKGYSVD
LGLFFKFLKVYKGLENNIELEKIEEVEISDLGDNFIKDITLSDIYAFLAFLEKVRNNSAYARARKVATLKSFFKFLNSKI
KLIDENPTVELESPKINKRHPVYLTLDQSITVLNSMDKGNKNYYRDYCILTLFLNCGMRLSELCNIEIEKIKGDTLTIIG
KGNKERTVYLNEASIAAIENYLKNRNDSKATEEAKKYLFLSSKYRPINKRSVEILVKKHIENAGFKDQKYTPHKLRHTAA
TLMYKYGNVDIRSLQNILGHENISTTQIYTHVDDETLREAVKTNPLANIK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=308, Percent_Identity=29.2207792207792, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790244, Length=225, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=29.6511627906977, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 52642; Mature: 52642

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNEANQFENFKYSQEIKELLNINLSNDDLNNLDHIYNYYDSQNIQRDYEDLIEDIYIFI
CCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FKRKLSITQLAEIYKVNQRIIKRWLKELGMDKLLEVEKGGDSVEKSNFKNSKQDELLEKN
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHC
KLKFDFLEKSKHPKRVIEFLNYLENVKGKSLNTVKGYSVDLGLFFKFLKVYKGLENNIEL
CCCEEHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHHCCCCCCCH
EKIEEVEISDLGDNFIKDITLSDIYAFLAFLEKVRNNSAYARARKVATLKSFFKFLNSKI
HHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCE
KLIDENPTVELESPKINKRHPVYLTLDQSITVLNSMDKGNKNYYRDYCILTLFLNCGMRL
EEEECCCCEEECCCCCCCCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
SELCNIEIEKIKGDTLTIIGKGNKERTVYLNEASIAAIENYLKNRNDSKATEEAKKYLFL
HHHCCCEEEEECCCEEEEEECCCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHC
SSKYRPINKRSVEILVKKHIENAGFKDQKYTPHKLRHTAATLMYKYGNVDIRSLQNILGH
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
ENISTTQIYTHVDDETLREAVKTNPLANIK
CCCCCEEEEEECCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNNEANQFENFKYSQEIKELLNINLSNDDLNNLDHIYNYYDSQNIQRDYEDLIEDIYIFI
CCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FKRKLSITQLAEIYKVNQRIIKRWLKELGMDKLLEVEKGGDSVEKSNFKNSKQDELLEKN
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHC
KLKFDFLEKSKHPKRVIEFLNYLENVKGKSLNTVKGYSVDLGLFFKFLKVYKGLENNIEL
CCCEEHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHHCCCCCCCH
EKIEEVEISDLGDNFIKDITLSDIYAFLAFLEKVRNNSAYARARKVATLKSFFKFLNSKI
HHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCE
KLIDENPTVELESPKINKRHPVYLTLDQSITVLNSMDKGNKNYYRDYCILTLFLNCGMRL
EEEECCCCEEECCCCCCCCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
SELCNIEIEKIKGDTLTIIGKGNKERTVYLNEASIAAIENYLKNRNDSKATEEAKKYLFL
HHHCCCEEEEECCCEEEEEECCCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHC
SSKYRPINKRSVEILVKKHIENAGFKDQKYTPHKLRHTAATLMYKYGNVDIRSLQNILGH
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
ENISTTQIYTHVDDETLREAVKTNPLANIK
CCCCCEEEEEECCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]