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The map label for this gene is hfq

Identifier: 18310140

GI number: 18310140

Start: 1356781

End: 1357023

Strand: Direct

Name: hfq

Synonym: CPE1158

Alternate gene names: 18310140

Gene position: 1356781-1357023 (Clockwise)

Preceding gene: 18310139

Following gene: 18310141

Centisome position: 44.76

GC content: 28.81

Gene sequence:

>243_bases
ATGAATAAGTCAATCAATAACCTACAAGATATATTCTTAAACAATGCAAGAAAGGAAAGAATTCCTGTAACAATATTTTT
AGTAAATGGGGTTCAATTAAAGGGTATCGTTAAAGGGTTCGATAGCTTTACAGTAGTTTTAGATAGTGATGGAAAGCAAC
AATTAGTTTATAAACATGCTATAAGCACAGTATCACCAGCTAAACCTATTTTATTTAATAATGCGCAAGTTTTTGATAAT
TAA

Upstream 100 bases:

>100_bases
TTCGCCTCTGAAGAAGATATTTCTTCCAAAATTATTAATGACATAATAAATTCTTAGGTTTATAATTAAATTATATTAAA
AATTTATGGAGGGCAATAGA

Downstream 100 bases:

>100_bases
ATATAGAAAAGAAAAATAGGTAAACCCTAGATGGTTTGCCTATTTTTTTTCTATATGATAAGATTTATAAATGTACGATA
TTTTAATAATGCGGGGGTAT

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 80

Protein sequence:

>80_residues
MNKSINNLQDIFLNNARKERIPVTIFLVNGVQLKGIVKGFDSFTVVLDSDGKQQLVYKHAISTVSPAKPILFNNAQVFDN

Sequences:

>Translated_80_residues
MNKSINNLQDIFLNNARKERIPVTIFLVNGVQLKGIVKGFDSFTVVLDSDGKQQLVYKHAISTVSPAKPILFNNAQVFDN
>Mature_80_residues
MNKSINNLQDIFLNNARKERIPVTIFLVNGVQLKGIVKGFDSFTVVLDSDGKQQLVYKHAISTVSPAKPILFNNAQVFDN

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=71, Percent_Identity=52.112676056338, Blast_Score=78, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_CLOP1 (Q0TRD3)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_695807.1
- ProteinModelPortal:   Q0TRD3
- SMR:   Q0TRD3
- STRING:   Q0TRD3
- GeneID:   4202553
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_1361
- TIGR:   CPF_1361
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- ProtClustDB:   CLSK810992
- BioCyc:   CPER195103:CPF_1361-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 8933; Mature: 8933

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSINNLQDIFLNNARKERIPVTIFLVNGVQLKGIVKGFDSFTVVLDSDGKQQLVYKHA
CCCCHHHHHHHHHCCCCCCCCCEEEEEECCEEEEHEECCCCEEEEEECCCCCHHHHHHHH
ISTVSPAKPILFNNAQVFDN
HCCCCCCCCEEECCEEECCC
>Mature Secondary Structure
MNKSINNLQDIFLNNARKERIPVTIFLVNGVQLKGIVKGFDSFTVVLDSDGKQQLVYKHA
CCCCHHHHHHHHHCCCCCCCCCEEEEEECCEEEEHEECCCCEEEEEECCCCCHHHHHHHH
ISTVSPAKPILFNNAQVFDN
HCCCCCCCCEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA