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The map label for this gene is lytB [H]

Identifier: 18310067

GI number: 18310067

Start: 1288664

End: 1289512

Strand: Direct

Name: lytB [H]

Synonym: CPE1085

Alternate gene names: 18310067

Gene position: 1288664-1289512 (Clockwise)

Preceding gene: 18310066

Following gene: 18310068

Centisome position: 42.51

GC content: 29.09

Gene sequence:

>849_bases
ATGGAAAGAAACGTAATTTTAGCTAAGAATGCTGGCTTTTGCTTTGGAGTAAAAAGAGCAGTTGATGAAGCTATAAAATA
TCAAAAAGAATTTGGAAAGAAAATATATACTTTAGGACCACTTATTCATAACAATGATGTTGTTAATTATTTAGAGGATA
ATAATATATTTGCAATTGAACTTTCAGATGCTGATTCTTTAAAGAAGGGGGATGTTGTACTTATAAGATCCCACGGAGTT
AAAGAAAGTGTAATAAAAGATTTAACAGACAAGGGTTTAATTGTTAAAAATGCAACTTGTCCATATGTAACTAACATTCA
ACTAAAAGTTAAAAAATGTTATGAACAAGGATATAAGATAATAATTGTTGGGGATAAAAATCACCCAGAAGTTATTGGAA
TTAATGGGTGGTGTAATGATTCTGCCATAATAACAAATGGAAAAACAGAACTTGAAAATATTCCAGCAAAGGTTTGTGTA
GTTTCACAAACTACTGAGAAAAAAGAAACTTGGAACAAGGTTTTAAATGAAATAGTAAGAGCAAGTAAAGAAATAGTTGC
TTTTAACACTATTTGTTCAGCTACTGATGTTAGACAAAAAAGTGTACAAGAGCTTTCAAAAGAGGCTGATTTAGTTTTTG
TTATAGGTGGAAAGAATAGTTCTAATACAACAAAATTATATGAAATATGCAAAAAGGAATGTCCTAAGAGCTATCATATA
GAAAATGTTAAAGAATTAGATGAAAGCCTATTAGAAGATGAAAGTGTTAAAACTATAGGAATTACTGCTGGGGCTTCAAC
TCCAGATTGGATAATAAATGAAGTGATTTCTAAGATTAAAGAATTATAA

Upstream 100 bases:

>100_bases
GATCCTCTAAGAAAAGCTGAGGATGCTATTGAAATTGATACTACTGGCATAGGCATAATGGGAGTAGTTGAAAAGATATC
TAGCTACATGGAGAAATAGT

Downstream 100 bases:

>100_bases
TTTTTAAATGTAATCCTGCAATTTAATTCATAATTATTTTGTACTACTGGTATTAAACTGGGAATTGTTTTATACTATAA
ATATATGACGAAGTTTTAGG

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MERNVILAKNAGFCFGVKRAVDEAIKYQKEFGKKIYTLGPLIHNNDVVNYLEDNNIFAIELSDADSLKKGDVVLIRSHGV
KESVIKDLTDKGLIVKNATCPYVTNIQLKVKKCYEQGYKIIIVGDKNHPEVIGINGWCNDSAIITNGKTELENIPAKVCV
VSQTTEKKETWNKVLNEIVRASKEIVAFNTICSATDVRQKSVQELSKEADLVFVIGGKNSSNTTKLYEICKKECPKSYHI
ENVKELDESLLEDESVKTIGITAGASTPDWIINEVISKIKEL

Sequences:

>Translated_282_residues
MERNVILAKNAGFCFGVKRAVDEAIKYQKEFGKKIYTLGPLIHNNDVVNYLEDNNIFAIELSDADSLKKGDVVLIRSHGV
KESVIKDLTDKGLIVKNATCPYVTNIQLKVKKCYEQGYKIIIVGDKNHPEVIGINGWCNDSAIITNGKTELENIPAKVCV
VSQTTEKKETWNKVLNEIVRASKEIVAFNTICSATDVRQKSVQELSKEADLVFVIGGKNSSNTTKLYEICKKECPKSYHI
ENVKELDESLLEDESVKTIGITAGASTPDWIINEVISKIKEL
>Mature_282_residues
MERNVILAKNAGFCFGVKRAVDEAIKYQKEFGKKIYTLGPLIHNNDVVNYLEDNNIFAIELSDADSLKKGDVVLIRSHGV
KESVIKDLTDKGLIVKNATCPYVTNIQLKVKKCYEQGYKIIIVGDKNHPEVIGINGWCNDSAIITNGKTELENIPAKVCV
VSQTTEKKETWNKVLNEIVRASKEIVAFNTICSATDVRQKSVQELSKEADLVFVIGGKNSSNTTKLYEICKKECPKSYHI
ENVKELDESLLEDESVKTIGITAGASTPDWIINEVISKIKEL

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=292, Percent_Identity=29.4520547945205, Blast_Score=145, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 31409; Mature: 31409

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERNVILAKNAGFCFGVKRAVDEAIKYQKEFGKKIYTLGPLIHNNDVVNYLEDNNIFAIE
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCEEEEEECCCEEEEE
LSDADSLKKGDVVLIRSHGVKESVIKDLTDKGLIVKNATCPYVTNIQLKVKKCYEQGYKI
ECCCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCEEEEEEEHEEHHHHCCCEE
IIVGDKNHPEVIGINGWCNDSAIITNGKTELENIPAKVCVVSQTTEKKETWNKVLNEIVR
EEEECCCCCCEEEECCCCCCCEEEECCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHH
ASKEIVAFNTICSATDVRQKSVQELSKEADLVFVIGGKNSSNTTKLYEICKKECPKSYHI
HHHHEEEEHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCH
ENVKELDESLLEDESVKTIGITAGASTPDWIINEVISKIKEL
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERNVILAKNAGFCFGVKRAVDEAIKYQKEFGKKIYTLGPLIHNNDVVNYLEDNNIFAIE
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCEEEEEECCCEEEEE
LSDADSLKKGDVVLIRSHGVKESVIKDLTDKGLIVKNATCPYVTNIQLKVKKCYEQGYKI
ECCCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCEEEEEEEHEEHHHHCCCEE
IIVGDKNHPEVIGINGWCNDSAIITNGKTELENIPAKVCVVSQTTEKKETWNKVLNEIVR
EEEECCCCCCEEEECCCCCCCEEEECCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHH
ASKEIVAFNTICSATDVRQKSVQELSKEADLVFVIGGKNSSNTTKLYEICKKECPKSYHI
HHHHEEEEHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCH
ENVKELDESLLEDESVKTIGITAGASTPDWIINEVISKIKEL
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA