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The map label for this gene is hexR [C]

Identifier: 18310064

GI number: 18310064

Start: 1285574

End: 1286449

Strand: Direct

Name: hexR [C]

Synonym: CPE1082

Alternate gene names: 18310064

Gene position: 1285574-1286449 (Clockwise)

Preceding gene: 18310063

Following gene: 18310065

Centisome position: 42.41

GC content: 27.63

Gene sequence:

>876_bases
ATGGAAAGTCAAGATTTAATGAGATTAATTCAAGTTAAGTTTCCAAAGCTTAGTAAAGGACAAAAGCTTATAGCTGAATA
TATATTAAAGAATTATGATAAGGCTGCATTTATGACTGCTGCTAAATTAGGAAATAATGTTGGAGTAAGTGAATCTACAG
TGGTTAGATTTGCTACAGAGCTTGGTTTCTCAGGATATCCAAAGTTACAAAAAGCACTTCAAGAATTAATAAAGAATAAG
TTAACATCTGTTCAAAGATTAGAGTTATCTAATGATTTTATAAGTGAAGAAAATGCTCTAAAAGGTGTTTTAAAAGCGGA
TATAGAAAATATAAGAGCAACATTAGAAAAGATAAATCATAAAACTTTTGATGAAGTGGTAAATGAAATATTCAAAGCTA
AAAGAATATATATAATAGGACTTAGAAGTTCTACTGCTCTTGCAGAATTTTTAGGATTTTACTTAAATTTAATATTAGAT
AATGTAAGAGTAATTTCAAATGGAATAAGCGATACTTTTGAACAAATGCTTAACTTAGGGGAAGGCGACTTAGTTATAGG
TATAGGTTTCCCAAGATATGCATTAAAAACAATAGATGCTTTAGAATTTGCTAAAACTAGAAATGCTAAAATAGTTTCTA
TTACAGATAGTTTAATTTCTCCTTTAGCATCTCAATCTGATCATACACTTATAGCTCAAAGTAATATGGCTTCATTTGTA
GATTCATTAGTTGCACCTTTAAGTGTAATAAATGCATTAATCATAGCTGTTGGTATAAGAGAAAAAGAGAAGATAACATC
AACATTTAGTGAGTTAGAAAAGATATGGAAAGACTATAATGTTTATTCATATAATAAAAATAATATAGAACCTTAA

Upstream 100 bases:

>100_bases
CATACAGAATTTACAAACAGAGCTAAGAGTGCACCTTCTTTAGTTGTTATTGAAAAGAAGTTTAAATAAGATTTAAGTAA
GTATAGAGAGGATTTTTAAA

Downstream 100 bases:

>100_bases
TAAAAAGCTGTATAAAGGTATAAAGAACATATAAATTATTTTAAGATAGAGCATAAATTTTATTCTATTATATAATTTAT
AAGTTTCATAAATTATATCT

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MESQDLMRLIQVKFPKLSKGQKLIAEYILKNYDKAAFMTAAKLGNNVGVSESTVVRFATELGFSGYPKLQKALQELIKNK
LTSVQRLELSNDFISEENALKGVLKADIENIRATLEKINHKTFDEVVNEIFKAKRIYIIGLRSSTALAEFLGFYLNLILD
NVRVISNGISDTFEQMLNLGEGDLVIGIGFPRYALKTIDALEFAKTRNAKIVSITDSLISPLASQSDHTLIAQSNMASFV
DSLVAPLSVINALIIAVGIREKEKITSTFSELEKIWKDYNVYSYNKNNIEP

Sequences:

>Translated_291_residues
MESQDLMRLIQVKFPKLSKGQKLIAEYILKNYDKAAFMTAAKLGNNVGVSESTVVRFATELGFSGYPKLQKALQELIKNK
LTSVQRLELSNDFISEENALKGVLKADIENIRATLEKINHKTFDEVVNEIFKAKRIYIIGLRSSTALAEFLGFYLNLILD
NVRVISNGISDTFEQMLNLGEGDLVIGIGFPRYALKTIDALEFAKTRNAKIVSITDSLISPLASQSDHTLIAQSNMASFV
DSLVAPLSVINALIIAVGIREKEKITSTFSELEKIWKDYNVYSYNKNNIEP
>Mature_291_residues
MESQDLMRLIQVKFPKLSKGQKLIAEYILKNYDKAAFMTAAKLGNNVGVSESTVVRFATELGFSGYPKLQKALQELIKNK
LTSVQRLELSNDFISEENALKGVLKADIENIRATLEKINHKTFDEVVNEIFKAKRIYIIGLRSSTALAEFLGFYLNLILD
NVRVISNGISDTFEQMLNLGEGDLVIGIGFPRYALKTIDALEFAKTRNAKIVSITDSLISPLASQSDHTLIAQSNMASFV
DSLVAPLSVINALIIAVGIREKEKITSTFSELEKIWKDYNVYSYNKNNIEP

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=290, Percent_Identity=24.8275862068966, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082130, Length=154, Percent_Identity=29.8701298701299, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32508; Mature: 32508

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESQDLMRLIQVKFPKLSKGQKLIAEYILKNYDKAAFMTAAKLGNNVGVSESTVVRFATE
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
LGFSGYPKLQKALQELIKNKLTSVQRLELSNDFISEENALKGVLKADIENIRATLEKINH
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KTFDEVVNEIFKAKRIYIIGLRSSTALAEFLGFYLNLILDNVRVISNGISDTFEQMLNLG
HHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
EGDLVIGIGFPRYALKTIDALEFAKTRNAKIVSITDSLISPLASQSDHTLIAQSNMASFV
CCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCEEEEHHHHHHHH
DSLVAPLSVINALIIAVGIREKEKITSTFSELEKIWKDYNVYSYNKNNIEP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
>Mature Secondary Structure
MESQDLMRLIQVKFPKLSKGQKLIAEYILKNYDKAAFMTAAKLGNNVGVSESTVVRFATE
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
LGFSGYPKLQKALQELIKNKLTSVQRLELSNDFISEENALKGVLKADIENIRATLEKINH
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KTFDEVVNEIFKAKRIYIIGLRSSTALAEFLGFYLNLILDNVRVISNGISDTFEQMLNLG
HHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
EGDLVIGIGFPRYALKTIDALEFAKTRNAKIVSITDSLISPLASQSDHTLIAQSNMASFV
CCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCEEEEHHHHHHHH
DSLVAPLSVINALIIAVGIREKEKITSTFSELEKIWKDYNVYSYNKNNIEP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]