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The map label for this gene is alr [H]

Identifier: 18310043

GI number: 18310043

Start: 1268707

End: 1269759

Strand: Direct

Name: alr [H]

Synonym: CPE1061

Alternate gene names: 18310043

Gene position: 1268707-1269759 (Clockwise)

Preceding gene: 18310042

Following gene: 18310044

Centisome position: 41.85

GC content: 25.83

Gene sequence:

>1053_bases
ATGAGTAATTATTTTTGGTGCGATGTAAATTTAAAAAATATAGAGAATAATATAAATGTAATAAGAGATTTAATACAAAA
TAAAAAGCTGATTGCAGTTATAAAGGGAGATGCTTATGGATTAGGCAGTAAAGAAATTGCTGAATTTATAGAAGATAAGG
TTGACATAATAGCAGTAGGTAATATTGATGAAAGCTTATGCTTAGATAATATTAATAAGGATATACTTATCTTATCACCT
TTATGTACAAAAGATGATTTTAAAGATGAAAGAGATAATTTAATATTAACTTTAGATAATGAGGAAATATTAAATGAATT
AGATAAGGAAACAAAGAAAAGAGTACATATATATGTAGATACAGGTATGAACAGAATGGGTATAAAGCCTAACAAGTTAG
ATTCATTTATAGAAAGAGTTAAAAATGAATTTCCTAACCTTGAAATAGATGGTATCTATACTCATTTACATAATGCTAAG
GATGTTAATTATACCTTAAAACAAATAGAATTATTTAAATCTACAGTTGAAAAGTATAAAGATAAAGTAAGAATAATACA
CTGCATGGCGTCAAGTGCTGTTGTAAATGATCAATTAAGAAAAGCATGTGATTTTACTACAGGGGCAAGAGCCGGTAATG
TGCTTTATGGATATATAGGCTTTAATAAAGGAATTAAAAAAACTTATGAATACTATGCAAAACCAGTAAATACCTATAAA
GTTTCAAAGGGACAAACTGTAGGATATGGTTGTCTTTTTAAGGCAGATAAGGATATGGAAATAGGAATAATTGAATGTGG
TAATGTTCATGGCTTAGGCATAAGTAGAGAAATTAAAAATAATGTTTTCTATGATATATTTAGAATGATTTATAGAAGAT
TTAAAGAGAGAAGTGTAATATTTAATAACAATGTACCTGTAAAAATATTAGGAAAAGTAAATATGAATATAACTATTATT
TCTATGGAAAACTGCTCTAAAGATTCAGTTTTAAAAGTTGATATTTCACCTATAATATCAGATTCAAGCATAGAAAAAAG
ATATATTTATTAG

Upstream 100 bases:

>100_bases
AAAGGGATTTTTTTATTTAGGTATAAATTAGTAATTTATATATTCATAAAAAAATGTTATCATATAAAATGTAATTTCAA
TGTAGAAAGAGGATTTTAAA

Downstream 100 bases:

>100_bases
AAGCAAAAATTTATAGTTTTAAGAAACATAAGGCTAAACAAATCTAGTCTTATGTTTTTTTTATTTTTTGTAATATTTTA
AGAGTTAAAACACTACCTTT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSNYFWCDVNLKNIENNINVIRDLIQNKKLIAVIKGDAYGLGSKEIAEFIEDKVDIIAVGNIDESLCLDNINKDILILSP
LCTKDDFKDERDNLILTLDNEEILNELDKETKKRVHIYVDTGMNRMGIKPNKLDSFIERVKNEFPNLEIDGIYTHLHNAK
DVNYTLKQIELFKSTVEKYKDKVRIIHCMASSAVVNDQLRKACDFTTGARAGNVLYGYIGFNKGIKKTYEYYAKPVNTYK
VSKGQTVGYGCLFKADKDMEIGIIECGNVHGLGISREIKNNVFYDIFRMIYRRFKERSVIFNNNVPVKILGKVNMNITII
SMENCSKDSVLKVDISPIISDSSIEKRYIY

Sequences:

>Translated_350_residues
MSNYFWCDVNLKNIENNINVIRDLIQNKKLIAVIKGDAYGLGSKEIAEFIEDKVDIIAVGNIDESLCLDNINKDILILSP
LCTKDDFKDERDNLILTLDNEEILNELDKETKKRVHIYVDTGMNRMGIKPNKLDSFIERVKNEFPNLEIDGIYTHLHNAK
DVNYTLKQIELFKSTVEKYKDKVRIIHCMASSAVVNDQLRKACDFTTGARAGNVLYGYIGFNKGIKKTYEYYAKPVNTYK
VSKGQTVGYGCLFKADKDMEIGIIECGNVHGLGISREIKNNVFYDIFRMIYRRFKERSVIFNNNVPVKILGKVNMNITII
SMENCSKDSVLKVDISPIISDSSIEKRYIY
>Mature_349_residues
SNYFWCDVNLKNIENNINVIRDLIQNKKLIAVIKGDAYGLGSKEIAEFIEDKVDIIAVGNIDESLCLDNINKDILILSPL
CTKDDFKDERDNLILTLDNEEILNELDKETKKRVHIYVDTGMNRMGIKPNKLDSFIERVKNEFPNLEIDGIYTHLHNAKD
VNYTLKQIELFKSTVEKYKDKVRIIHCMASSAVVNDQLRKACDFTTGARAGNVLYGYIGFNKGIKKTYEYYAKPVNTYKV
SKGQTVGYGCLFKADKDMEIGIIECGNVHGLGISREIKNNVFYDIFRMIYRRFKERSVIFNNNVPVKILGKVNMNITIIS
MENCSKDSVLKVDISPIISDSSIEKRYIY

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=341, Percent_Identity=23.4604105571848, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40125; Mature: 39994

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYFWCDVNLKNIENNINVIRDLIQNKKLIAVIKGDAYGLGSKEIAEFIEDKVDIIAVG
CCCEEEEEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHCCEEEEEEC
NIDESLCLDNINKDILILSPLCTKDDFKDERDNLILTLDNEEILNELDKETKKRVHIYVD
CCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCEEEEEEE
TGMNRMGIKPNKLDSFIERVKNEFPNLEIDGIYTHLHNAKDVNYTLKQIELFKSTVEKYK
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
DKVRIIHCMASSAVVNDQLRKACDFTTGARAGNVLYGYIGFNKGIKKTYEYYAKPVNTYK
HHEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEE
VSKGQTVGYGCLFKADKDMEIGIIECGNVHGLGISREIKNNVFYDIFRMIYRRFKERSVI
ECCCCEECEEEEEECCCCCEEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHCCEEE
FNNNVPVKILGKVNMNITIISMENCSKDSVLKVDISPIISDSSIEKRYIY
ECCCCCEEEEEEECCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNYFWCDVNLKNIENNINVIRDLIQNKKLIAVIKGDAYGLGSKEIAEFIEDKVDIIAVG
CCEEEEEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHCCEEEEEEC
NIDESLCLDNINKDILILSPLCTKDDFKDERDNLILTLDNEEILNELDKETKKRVHIYVD
CCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCEEEEEEE
TGMNRMGIKPNKLDSFIERVKNEFPNLEIDGIYTHLHNAKDVNYTLKQIELFKSTVEKYK
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
DKVRIIHCMASSAVVNDQLRKACDFTTGARAGNVLYGYIGFNKGIKKTYEYYAKPVNTYK
HHEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEE
VSKGQTVGYGCLFKADKDMEIGIIECGNVHGLGISREIKNNVFYDIFRMIYRRFKERSVI
ECCCCEECEEEEEECCCCCEEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHCCEEE
FNNNVPVKILGKVNMNITIISMENCSKDSVLKVDISPIISDSSIEKRYIY
ECCCCCEEEEEEECCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]