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The map label for this gene is cobT [H]

Identifier: 18310016

GI number: 18310016

Start: 1236168

End: 1237253

Strand: Direct

Name: cobT [H]

Synonym: CPE1034

Alternate gene names: 18310016

Gene position: 1236168-1237253 (Clockwise)

Preceding gene: 18310014

Following gene: 18310017

Centisome position: 40.78

GC content: 30.66

Gene sequence:

>1086_bases
ATGTTAAATGAGGTGTTAAAAGGAATAGAAGGTTTAGATAATGACATGATTGTAAAAGCTAAAAATAGAGTAGATTCTTT
AGCTAAACCTTTAGGAAGTTTAGGAAAGTTAGAAGATATAGCCATAAGGTTATCTGGAATAACTGGAAATATGTTTAATA
ATATTGATAAAAAGTGTGTGATTATAATGTCTTCTGACAATGGAGTTGAAGAAGAAGGAGTAGCCTCAGCACCTCAATGT
GTAACCTTACTTCAAACAAAAAACTTTATAAAAGGTACTACGGGAGTAGCTACATTGGCAAAAGCTAATGGAACAGATTT
AATGGTTTTTGATGTGGGAATTAATTCAGATGAAGTTGTAGAAGGAGTTATAAATAGAAAGATATCAAAGGGAACTAAAA
ATATTTATAAGGAACCAGCTATGACTTATGAAGAAGCTAAAAAATCCTTAGAAATTGGAATAGAAGCTGTAAAAATAGCT
AAGGAAAAGGGATATAAAATACTTGGAGTAGGTGAAATGGGAATAGGAAATACCACTACTTCAGCAGCAGTATTAAAAGC
ACTTATTGGGTGTGAAACTTCTCAAGTAGTAGGAAAAGGTGGAGGAATAAATAATGATTCTTTCGAAAAGAAAAAAAGAA
TTGTAGAAGAAGTGGTTAAAAAACATAATATTAATTTTGATGATTCTATTGATATTATTTCAAAGGTTGGAGGATATGAT
ATTGGAGCAATGACAGGTGTATTTTTAGGCGCAGCTTTCTATAGAATCCCTGTAGTAATAGATGGATTTATATCCGTTGT
GACAGCTCTTTTAGCTAATAGATTAAATCCTTTAGTTAAAGAATTTTGTTTTACTTCTCATAAATCACAAGAAATAGGAT
ATGAGTTAGCTATAAAAGAGTTAGGTTTAGATCCTATGTTAGATTTAAATATGAGATTAGGAGAAGGAAGTGGATGTCCA
ATAGCTTTCTCAGTAATTGATTTTGCAACAGCCATGATGAATAATATGGCAACTTTTGAAGAAGGAAATATAGATAACAG
CTATTTAGAAGATGTAAAGGATGAAGAATGTTATATTGTTCTTTAA

Upstream 100 bases:

>100_bases
TTTGGTTATCTTATGATTTTTCATTTTGTTAGTCATCTTAATCTCCTTATATTCTAATGAAAATATTATATCAAAAAATA
AGAAGGGATGGAAAAGGATA

Downstream 100 bases:

>100_bases
ACCTTTAAAAATATTATAGGAGTTAATTTAATTAGTTATGATAGTTTTAATTATTGGAGGAGCTAAGAGTAGCAAATCTT
CTTATGCTGAATTTTATAGT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLNEVLKGIEGLDNDMIVKAKNRVDSLAKPLGSLGKLEDIAIRLSGITGNMFNNIDKKCVIIMSSDNGVEEEGVASAPQC
VTLLQTKNFIKGTTGVATLAKANGTDLMVFDVGINSDEVVEGVINRKISKGTKNIYKEPAMTYEEAKKSLEIGIEAVKIA
KEKGYKILGVGEMGIGNTTTSAAVLKALIGCETSQVVGKGGGINNDSFEKKKRIVEEVVKKHNINFDDSIDIISKVGGYD
IGAMTGVFLGAAFYRIPVVIDGFISVVTALLANRLNPLVKEFCFTSHKSQEIGYELAIKELGLDPMLDLNMRLGEGSGCP
IAFSVIDFATAMMNNMATFEEGNIDNSYLEDVKDEECYIVL

Sequences:

>Translated_361_residues
MLNEVLKGIEGLDNDMIVKAKNRVDSLAKPLGSLGKLEDIAIRLSGITGNMFNNIDKKCVIIMSSDNGVEEEGVASAPQC
VTLLQTKNFIKGTTGVATLAKANGTDLMVFDVGINSDEVVEGVINRKISKGTKNIYKEPAMTYEEAKKSLEIGIEAVKIA
KEKGYKILGVGEMGIGNTTTSAAVLKALIGCETSQVVGKGGGINNDSFEKKKRIVEEVVKKHNINFDDSIDIISKVGGYD
IGAMTGVFLGAAFYRIPVVIDGFISVVTALLANRLNPLVKEFCFTSHKSQEIGYELAIKELGLDPMLDLNMRLGEGSGCP
IAFSVIDFATAMMNNMATFEEGNIDNSYLEDVKDEECYIVL
>Mature_361_residues
MLNEVLKGIEGLDNDMIVKAKNRVDSLAKPLGSLGKLEDIAIRLSGITGNMFNNIDKKCVIIMSSDNGVEEEGVASAPQC
VTLLQTKNFIKGTTGVATLAKANGTDLMVFDVGINSDEVVEGVINRKISKGTKNIYKEPAMTYEEAKKSLEIGIEAVKIA
KEKGYKILGVGEMGIGNTTTSAAVLKALIGCETSQVVGKGGGINNDSFEKKKRIVEEVVKKHNINFDDSIDIISKVGGYD
IGAMTGVFLGAAFYRIPVVIDGFISVVTALLANRLNPLVKEFCFTSHKSQEIGYELAIKELGLDPMLDLNMRLGEGSGCP
IAFSVIDFATAMMNNMATFEEGNIDNSYLEDVKDEECYIVL

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=345, Percent_Identity=40, Blast_Score=272, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 38887; Mature: 38887

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNEVLKGIEGLDNDMIVKAKNRVDSLAKPLGSLGKLEDIAIRLSGITGNMFNNIDKKCV
CHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHCCCCEEE
IIMSSDNGVEEEGVASAPQCVTLLQTKNFIKGTTGVATLAKANGTDLMVFDVGINSDEVV
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHEECCCCEEEEEEECCCHHHHH
EGVINRKISKGTKNIYKEPAMTYEEAKKSLEIGIEAVKIAKEKGYKILGVGEMGIGNTTT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHH
SAAVLKALIGCETSQVVGKGGGINNDSFEKKKRIVEEVVKKHNINFDDSIDIISKVGGYD
HHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
IGAMTGVFLGAAFYRIPVVIDGFISVVTALLANRLNPLVKEFCFTSHKSQEIGYELAIKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHH
LGLDPMLDLNMRLGEGSGCPIAFSVIDFATAMMNNMATFEEGNIDNSYLEDVKDEECYIV
HCCCCEEECCEEECCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEE
L
C
>Mature Secondary Structure
MLNEVLKGIEGLDNDMIVKAKNRVDSLAKPLGSLGKLEDIAIRLSGITGNMFNNIDKKCV
CHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHCCCCEEE
IIMSSDNGVEEEGVASAPQCVTLLQTKNFIKGTTGVATLAKANGTDLMVFDVGINSDEVV
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHEECCCCEEEEEEECCCHHHHH
EGVINRKISKGTKNIYKEPAMTYEEAKKSLEIGIEAVKIAKEKGYKILGVGEMGIGNTTT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHH
SAAVLKALIGCETSQVVGKGGGINNDSFEKKKRIVEEVVKKHNINFDDSIDIISKVGGYD
HHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
IGAMTGVFLGAAFYRIPVVIDGFISVVTALLANRLNPLVKEFCFTSHKSQEIGYELAIKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHH
LGLDPMLDLNMRLGEGSGCPIAFSVIDFATAMMNNMATFEEGNIDNSYLEDVKDEECYIV
HCCCCEEECCEEECCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEE
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA