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The map label for this gene is ttcA [H]

Identifier: 18309972

GI number: 18309972

Start: 1193131

End: 1193865

Strand: Reverse

Name: ttcA [H]

Synonym: CPE0990

Alternate gene names: 18309972

Gene position: 1193865-1193131 (Counterclockwise)

Preceding gene: 18309974

Following gene: 18309967

Centisome position: 39.38

GC content: 29.12

Gene sequence:

>735_bases
ATGAAAACCATGCAAAAATTATTAAGTAAAACTAGACAAGCTATAAAAGAATATAACCTTATTGAAGATGGTGATAAAAT
AGCTGTAGGACTTTCTGGTGGAAAGGATAGTCTAACACTTTTACATATATTAAAAAACTATCAAAGATTTTCTCCTGAAA
AATTTGAATTAATAGCTATAACTTTAAATCCTGGAGGAGTTGATAACAGTCCATTACATGAGCTTTGTAAAAATATAGAT
GTTCCTTTTTATGAAATTCAAACAGATATAAAGGAAATAGTTTTTGATATAAAGAAAGAAAAAAATCCATGCTCCTTATG
TGCAAATCTCAGAAGAGGTGCATTAAATGATAATGCTGAAAAGCTTGGTTGCAACAAAGTTGCCTTAGGACACCATAAAG
ATGATGCCTTAGAAACCCTTATGCTCTCCATAAGCTATGAAGGAAGAATAAACTGCTTCTCTCCTAAAAGCTTTATGCAT
AAAAATAATTTAACTCTTATAAGACCTATGGTGTTTATTGAGGAAAGCCAAATAAGAAAGGCAGTAGCAGAATATAATTT
CCCAGTGATAAAAAATCCTTGTCCTGCAGATGGTAAAACTAAAAGAGAAGATATGAAAAATCTTATTAGAAGTTTAGATA
AAACTATGCCTGGTTTTAAGAAAAATTTATTTAAATCTTTAACTAATACTGATCAAATGTTTGTATGGGATAAAGAAATA
GTAAAGAAAATGTAA

Upstream 100 bases:

>100_bases
ATATCTGACAACAAATTTAATTTTATTCTAAAATTTTCACTCTTTTAATTTTCACCTTTTTATTATAAGATAATTAAATA
AAGATTAAGAGGTGATTTTT

Downstream 100 bases:

>100_bases
AAAGTGTACAAGTTAATACTTGTACACTTTTTTTGTAAATACATAATATAAATTTATATTATTAAAATTACTTACCAAAT
ACTTTTTTCTTCAACATAAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MKTMQKLLSKTRQAIKEYNLIEDGDKIAVGLSGGKDSLTLLHILKNYQRFSPEKFELIAITLNPGGVDNSPLHELCKNID
VPFYEIQTDIKEIVFDIKKEKNPCSLCANLRRGALNDNAEKLGCNKVALGHHKDDALETLMLSISYEGRINCFSPKSFMH
KNNLTLIRPMVFIEESQIRKAVAEYNFPVIKNPCPADGKTKREDMKNLIRSLDKTMPGFKKNLFKSLTNTDQMFVWDKEI
VKKM

Sequences:

>Translated_244_residues
MKTMQKLLSKTRQAIKEYNLIEDGDKIAVGLSGGKDSLTLLHILKNYQRFSPEKFELIAITLNPGGVDNSPLHELCKNID
VPFYEIQTDIKEIVFDIKKEKNPCSLCANLRRGALNDNAEKLGCNKVALGHHKDDALETLMLSISYEGRINCFSPKSFMH
KNNLTLIRPMVFIEESQIRKAVAEYNFPVIKNPCPADGKTKREDMKNLIRSLDKTMPGFKKNLFKSLTNTDQMFVWDKEI
VKKM
>Mature_244_residues
MKTMQKLLSKTRQAIKEYNLIEDGDKIAVGLSGGKDSLTLLHILKNYQRFSPEKFELIAITLNPGGVDNSPLHELCKNID
VPFYEIQTDIKEIVFDIKKEKNPCSLCANLRRGALNDNAEKLGCNKVALGHHKDDALETLMLSISYEGRINCFSPKSFMH
KNNLTLIRPMVFIEESQIRKAVAEYNFPVIKNPCPADGKTKREDMKNLIRSLDKTMPGFKKNLFKSLTNTDQMFVWDKEI
VKKM

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=233, Percent_Identity=35.6223175965665, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI193211090, Length=233, Percent_Identity=31.3304721030043, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17540090, Length=227, Percent_Identity=25.1101321585903, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 27853; Mature: 27853

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTMQKLLSKTRQAIKEYNLIEDGDKIAVGLSGGKDSLTLLHILKNYQRFSPEKFELIAI
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEE
TLNPGGVDNSPLHELCKNIDVPFYEIQTDIKEIVFDIKKEKNPCSLCANLRRGALNDNAE
EECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHH
KLGCNKVALGHHKDDALETLMLSISYEGRINCFSPKSFMHKNNLTLIRPMVFIEESQIRK
HHCCCCEECCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCEEEHHHHHHHHHHHHH
AVAEYNFPVIKNPCPADGKTKREDMKNLIRSLDKTMPGFKKNLFKSLTNTDQMFVWDKEI
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECHHH
VKKM
HHCC
>Mature Secondary Structure
MKTMQKLLSKTRQAIKEYNLIEDGDKIAVGLSGGKDSLTLLHILKNYQRFSPEKFELIAI
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEE
TLNPGGVDNSPLHELCKNIDVPFYEIQTDIKEIVFDIKKEKNPCSLCANLRRGALNDNAE
EECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHH
KLGCNKVALGHHKDDALETLMLSISYEGRINCFSPKSFMHKNNLTLIRPMVFIEESQIRK
HHCCCCEECCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCEEEHHHHHHHHHHHHH
AVAEYNFPVIKNPCPADGKTKREDMKNLIRSLDKTMPGFKKNLFKSLTNTDQMFVWDKEI
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECHHH
VKKM
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA