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The map label for this gene is sipS [H]

Identifier: 18309579

GI number: 18309579

Start: 745148

End: 745678

Strand: Direct

Name: sipS [H]

Synonym: CPE0597

Alternate gene names: 18309579

Gene position: 745148-745678 (Clockwise)

Preceding gene: 18309578

Following gene: 18309580

Centisome position: 24.58

GC content: 28.63

Gene sequence:

>531_bases
ATGAGTTCTAGTAATACAAAGAAGAAATCATTCTTTTTAGATTGGATTATACCAATTTTAGCAGCTTTACTATTAGCAGC
TTTGATTCATCAATTTTTATTGTTTAAGATAAAAGTTCCTACAGGATCAATGATGCCTACAGTAGAGATTGGTGATCAAT
TATTTGTTACTAAAATATATAATCCTAATAATATCAAAAGAGGAGATATAGTCGTTTTTAATTCTGATGAATTAAAAGAA
CCACTTTTAAAACGTGTCATTGGATTACCAGGTGAGCATGTTGAAATAAAAAGTGATGGTTCAGTTTATATAAATGGAAA
TAAACTTGAAGAAGACTATGTAAAATATCAAGGTGGAAAAACTGATATGTCTTTTGATGTTCCAAGTGGAAAGTTTTTAA
TGTTAGGTGACAATAGAAATAATAGTGATGATGCTAGATATTGGAGCAATCCTTATATAGATGGAAAAGACATAGAAGCA
AAGGCACAGTTAACAGTATATCCTTTTGATAGAATAGGATTTGTAAAATAA

Upstream 100 bases:

>100_bases
TAGTTAAAGGCAAAGAGGGTAAGTTTTGCTTGGATAAAGCGCTTACAGAAAAAAGAAAAAAAGAAATAGAAGATTTGATG
AAAGGTATGTGGGAATAGTA

Downstream 100 bases:

>100_bases
ACGTTAGAGAAGGAGGAATGATGTATGTTTAAAGATAAAAAAATGCTTAAATATATTGTCATATATAGTATTATAGCGTT
TGGTATATTATTAACCTTTA

Product: signal peptidase type I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSSSNTKKKSFFLDWIIPILAALLLAALIHQFLLFKIKVPTGSMMPTVEIGDQLFVTKIYNPNNIKRGDIVVFNSDELKE
PLLKRVIGLPGEHVEIKSDGSVYINGNKLEEDYVKYQGGKTDMSFDVPSGKFLMLGDNRNNSDDARYWSNPYIDGKDIEA
KAQLTVYPFDRIGFVK

Sequences:

>Translated_176_residues
MSSSNTKKKSFFLDWIIPILAALLLAALIHQFLLFKIKVPTGSMMPTVEIGDQLFVTKIYNPNNIKRGDIVVFNSDELKE
PLLKRVIGLPGEHVEIKSDGSVYINGNKLEEDYVKYQGGKTDMSFDVPSGKFLMLGDNRNNSDDARYWSNPYIDGKDIEA
KAQLTVYPFDRIGFVK
>Mature_175_residues
SSSNTKKKSFFLDWIIPILAALLLAALIHQFLLFKIKVPTGSMMPTVEIGDQLFVTKIYNPNNIKRGDIVVFNSDELKEP
LLKRVIGLPGEHVEIKSDGSVYINGNKLEEDYVKYQGGKTDMSFDVPSGKFLMLGDNRNNSDDARYWSNPYIDGKDIEAK
AQLTVYPFDRIGFVK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 19882; Mature: 19751

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00760 SPASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSNTKKKSFFLDWIIPILAALLLAALIHQFLLFKIKVPTGSMMPTVEIGDQLFVTKIY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEECCCEEEEEEEE
NPNNIKRGDIVVFNSDELKEPLLKRVIGLPGEHVEIKSDGSVYINGNKLEEDYVKYQGGK
CCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCHHHHHCCCCC
TDMSFDVPSGKFLMLGDNRNNSDDARYWSNPYIDGKDIEAKAQLTVYPFDRIGFVK
CCEEEECCCCCEEEEECCCCCCCCCEECCCCCCCCCCCCEEEEEEEEECHHCCCCC
>Mature Secondary Structure 
SSSNTKKKSFFLDWIIPILAALLLAALIHQFLLFKIKVPTGSMMPTVEIGDQLFVTKIY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEECCCEEEEEEEE
NPNNIKRGDIVVFNSDELKEPLLKRVIGLPGEHVEIKSDGSVYINGNKLEEDYVKYQGGK
CCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCHHHHHCCCCC
TDMSFDVPSGKFLMLGDNRNNSDDARYWSNPYIDGKDIEAKAQLTVYPFDRIGFVK
CCEEEECCCCCEEEEECCCCCCCCCEECCCCCCCCCCCCEEEEEEEEECHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]