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The map label for this gene is rlmM [H]

Identifier: 182682524

GI number: 182682524

Start: 2252709

End: 2253809

Strand: Reverse

Name: rlmM [H]

Synonym: XfasM23_2011

Alternate gene names: 182682524

Gene position: 2253809-2252709 (Counterclockwise)

Preceding gene: 182682526

Following gene: 182682521

Centisome position: 88.88

GC content: 55.95

Gene sequence:

>1101_bases
ATGCGTGTGCTGCTGCATCAGCACCAACATGATGCAGGTGCGACGATGAGCGGTTTAATCGCTTACTGCCGTCAAGGGTT
TGAGCCGGAATTGGCGGCTGAATTGAGGGACCGCGCCGTATTACTCGGAATCGCCAGTGATATACACGCACAGCGTAATC
ATGGCTTCGTACTCTTGCGGTGCGATCCCCTTCATGTCGATACACTGCTACAGCAATTGCACTGGCGCCGCTTGATCTTC
GCGCGACAAACCCTGCGTTTACATGCCGAACTGAAAACACTCAACTCACGAGACCGCATTGCTCCCATCCTGGCAGCACT
CCCCAAGACACCATGCTTTGGTGATTTGTGGATTGAGTACCCAGACTCAGACATGGGCAAGCCATTAGCTGGACTAGCCC
GCAGTTTCGGCAACGCATTGCGTCCCGTACTGCGCAGTGCTGGTCGACTTTCCGCGCAGCTCCATCCACAGTGGCCACGC
CTGCACGTCTGCTTCCTGAGTGGTGACCACGTATTGCTAGGCAGCACACGTTCCGTTGACAGTGCGCCGTGGCAACTCGG
CATCCCGCGTTTGAAACTGTTGCCAGAGGCTCCATCACGCTCTGCACTTAAGTTGGAAGAGGCATTGATCACCCTGCTCA
CTCCGAACGAGCGTGAAGCCAAATTACGCCCTGGCATGTGTGCGACCGACCTAGGCGCAGCGCCCGGTGGTTGGACTTGG
GTATTGATTTGCCAGCATCTGCGCGTGACCAGCATTGACAATGCGGCATTGCGGCCACCACTGCTCAATCATCCATTGGT
CCAGCACGTGCGGGCCGATGGCTTTCGTTGGATACCGCCACGGCCAATGGATTGGATGGTCTGCGACATGGTTGAACAGC
CACGTCGGGTTGCAGAACGTATGGCTGTCTGGCTGCGTGAAGGGTGGTGTCGGCACATGATCTTTAATCTCAAGCTACCG
ATGAAAAAACGTTGGGATGAAACCCGATTGTGTTTGGAACGCTTCGAAACCCAGGCGGCAGTGCCACTGACCCTACGCGC
CAAGCAGTTGTATCATGACCGCGAAGAGATCACCGTTTATGCCAGCAACGACGCTCGGTAA

Upstream 100 bases:

>100_bases
AAGTAACCCCTACGAACGGCCGTCGCTGGCCACCTGAATTGACCCACCGCTTAAGCGCGAGATTGAGATTGAAGTCGTCC
CTACCCCGTCACACCGCCCC

Downstream 100 bases:

>100_bases
ATTTCTTCAATCACCCATTGATCACTTCATTCAGCATCACGCGACAGGCACATTGTATGGTTTTGGAACATCCTGTTTTT
ATGATTGCTGAATTTAAATA

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRVLLHQHQHDAGATMSGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLRCDPLHVDTLLQQLHWRRLIF
ARQTLRLHAELKTLNSRDRIAPILAALPKTPCFGDLWIEYPDSDMGKPLAGLARSFGNALRPVLRSAGRLSAQLHPQWPR
LHVCFLSGDHVLLGSTRSVDSAPWQLGIPRLKLLPEAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTW
VLICQHLRVTSIDNAALRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAERMAVWLREGWCRHMIFNLKLP
MKKRWDETRLCLERFETQAAVPLTLRAKQLYHDREEITVYASNDAR

Sequences:

>Translated_366_residues
MRVLLHQHQHDAGATMSGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLRCDPLHVDTLLQQLHWRRLIF
ARQTLRLHAELKTLNSRDRIAPILAALPKTPCFGDLWIEYPDSDMGKPLAGLARSFGNALRPVLRSAGRLSAQLHPQWPR
LHVCFLSGDHVLLGSTRSVDSAPWQLGIPRLKLLPEAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTW
VLICQHLRVTSIDNAALRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAERMAVWLREGWCRHMIFNLKLP
MKKRWDETRLCLERFETQAAVPLTLRAKQLYHDREEITVYASNDAR
>Mature_366_residues
MRVLLHQHQHDAGATMSGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLRCDPLHVDTLLQQLHWRRLIF
ARQTLRLHAELKTLNSRDRIAPILAALPKTPCFGDLWIEYPDSDMGKPLAGLARSFGNALRPVLRSAGRLSAQLHPQWPR
LHVCFLSGDHVLLGSTRSVDSAPWQLGIPRLKLLPEAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTW
VLICQHLRVTSIDNAALRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAERMAVWLREGWCRHMIFNLKLP
MKKRWDETRLCLERFETQAAVPLTLRAKQLYHDREEITVYASNDAR

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=352, Percent_Identity=41.4772727272727, Blast_Score=257, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 41737; Mature: 41737

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLHQHQHDAGATMSGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLR
CEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEHHHHHHCCCCCEEEEE
CDPLHVDTLLQQLHWRRLIFARQTLRLHAELKTLNSRDRIAPILAALPKTPCFGDLWIEY
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEC
PDSDMGKPLAGLARSFGNALRPVLRSAGRLSAQLHPQWPRLHVCFLSGDHVLLGSTRSVD
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEEEECCEEEEECCCCCC
SAPWQLGIPRLKLLPEAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTW
CCCCCCCCCCEEECCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCCCCHHCCCCCCCHHH
VLICQHLRVTSIDNAALRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAER
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHH
MAVWLREGWCRHMIFNLKLPMKKRWDETRLCLERFETQAAVPLTLRAKQLYHDREEITVY
HHHHHHHHHHHHHHEECCCCHHHCCCHHHHHHHHHHCCCCCCCEEHHHHHHCCCCCEEEE
ASNDAR
ECCCCC
>Mature Secondary Structure
MRVLLHQHQHDAGATMSGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLR
CEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEHHHHHHCCCCCEEEEE
CDPLHVDTLLQQLHWRRLIFARQTLRLHAELKTLNSRDRIAPILAALPKTPCFGDLWIEY
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEC
PDSDMGKPLAGLARSFGNALRPVLRSAGRLSAQLHPQWPRLHVCFLSGDHVLLGSTRSVD
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEEEECCEEEEECCCCCC
SAPWQLGIPRLKLLPEAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTW
CCCCCCCCCCEEECCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCCCCHHCCCCCCCHHH
VLICQHLRVTSIDNAALRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAER
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHH
MAVWLREGWCRHMIFNLKLPMKKRWDETRLCLERFETQAAVPLTLRAKQLYHDREEITVY
HHHHHHHHHHHHHHEECCCCHHHCCCHHHHHHHHHHCCCCCCCEEHHHHHHCCCCCEEEE
ASNDAR
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA