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The map label for this gene is purN

Identifier: 182682172

GI number: 182682172

Start: 1830145

End: 1830813

Strand: Direct

Name: purN

Synonym: XfasM23_1651

Alternate gene names: 182682172

Gene position: 1830145-1830813 (Clockwise)

Preceding gene: 182682171

Following gene: 182682173

Centisome position: 72.18

GC content: 57.55

Gene sequence:

>669_bases
TTGACCTCACCCTCCTCCCCTTTACGCCTCGCCATCCTGGCCTCAGGACGTGGCAGCAATCTGCAAGCCATCCTTGATGC
CATCGCGACCGACCGACTGCATGCCGAAGTGGTTGGAGTTTTTTCCGATCGCCCCGACGCACCCGCACTCACCAAAGTGT
TACCTAGGCACCGTTGGAGTGCAGATCCACACGACTCCCCTGATCGCATCAGCTTCGACACAACGCTCAGCGCAGCGATC
GCCGCCGTAACACCACACTGGGTCGTATGCGCAGGCTACATGCGCATCCTCAGCGCAGCATTTATAGAACGCTTCCCCAA
GCGAATCCTTAACATCCACCCCTCACTGCTTCCCAAACACCGCGGCTTAAACACGCATGCACGCGCACTGGCAGCAGGCG
ACACCGAACACGGTGCCAGCGTCCATCTTGTTATACCGGAACTAGATGCTGGAACGGTACTGGCCCAGGCAGTAGTTCCC
ATCCTTACCAATGACACCGCCGAAACGTTGGCCAAACGCGTGCTAGTACGCGAACATCCACTGCTCGTCGCCACCTTGGA
ACTACTTGCAAACGGTCGCCTGACGGTCGACGGACCAACACCGCAATTAGACACTCAGTACCTGTTTACACCACTGCGCC
TAGATTCACAGGGAACTCTCACCCGTTGA

Upstream 100 bases:

>100_bases
ACTGCAACAACCAGCAAAGCCCTTACTGGACACACACTGGCACACTACCAACCATACTTGGCTACTCTTGCCCTTTACCC
TAACTCAGGAAATCCACTGT

Downstream 100 bases:

>100_bases
CCATGCACACCACATCGGGACATCCACTGGAACATTCTTTTATTACCACCGGACTGCGCCACGTATGAAACGCTTCCTGT
CGCCCGTGCCTCTGTGCCTG

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTSPSSPLRLAILASGRGSNLQAILDAIATDRLHAEVVGVFSDRPDAPALTKVLPRHRWSADPHDSPDRISFDTTLSAAI
AAVTPHWVVCAGYMRILSAAFIERFPKRILNIHPSLLPKHRGLNTHARALAAGDTEHGASVHLVIPELDAGTVLAQAVVP
ILTNDTAETLAKRVLVREHPLLVATLELLANGRLTVDGPTPQLDTQYLFTPLRLDSQGTLTR

Sequences:

>Translated_222_residues
MTSPSSPLRLAILASGRGSNLQAILDAIATDRLHAEVVGVFSDRPDAPALTKVLPRHRWSADPHDSPDRISFDTTLSAAI
AAVTPHWVVCAGYMRILSAAFIERFPKRILNIHPSLLPKHRGLNTHARALAAGDTEHGASVHLVIPELDAGTVLAQAVVP
ILTNDTAETLAKRVLVREHPLLVATLELLANGRLTVDGPTPQLDTQYLFTPLRLDSQGTLTR
>Mature_221_residues
TSPSSPLRLAILASGRGSNLQAILDAIATDRLHAEVVGVFSDRPDAPALTKVLPRHRWSADPHDSPDRISFDTTLSAAIA
AVTPHWVVCAGYMRILSAAFIERFPKRILNIHPSLLPKHRGLNTHARALAAGDTEHGASVHLVIPELDAGTVLAQAVVPI
LTNDTAETLAKRVLVREHPLLVATLELLANGRLTVDGPTPQLDTQYLFTPLRLDSQGTLTR

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=188, Percent_Identity=36.7021276595745, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI209869995, Length=188, Percent_Identity=36.7021276595745, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI209869993, Length=188, Percent_Identity=36.7021276595745, Blast_Score=125, Evalue=3e-29,
Organism=Escherichia coli, GI1788846, Length=205, Percent_Identity=42.9268292682927, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1787483, Length=172, Percent_Identity=29.6511627906977, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17567511, Length=190, Percent_Identity=34.7368421052632, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6320616, Length=208, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582400, Length=208, Percent_Identity=36.5384615384615, Blast_Score=124, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 23945; Mature: 23814

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPSSPLRLAILASGRGSNLQAILDAIATDRLHAEVVGVFSDRPDAPALTKVLPRHRWS
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHCCCC
ADPHDSPDRISFDTTLSAAIAAVTPHWVVCAGYMRILSAAFIERFPKRILNIHPSLLPKH
CCCCCCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCC
RGLNTHARALAAGDTEHGASVHLVIPELDAGTVLAQAVVPILTNDTAETLAKRVLVREHP
CCCCHHHHHEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
LLVATLELLANGRLTVDGPTPQLDTQYLFTPLRLDSQGTLTR
HHHHHHHHHHCCCEEECCCCCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure 
TSPSSPLRLAILASGRGSNLQAILDAIATDRLHAEVVGVFSDRPDAPALTKVLPRHRWS
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHCCCC
ADPHDSPDRISFDTTLSAAIAAVTPHWVVCAGYMRILSAAFIERFPKRILNIHPSLLPKH
CCCCCCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCC
RGLNTHARALAAGDTEHGASVHLVIPELDAGTVLAQAVVPILTNDTAETLAKRVLVREHP
CCCCHHHHHEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
LLVATLELLANGRLTVDGPTPQLDTQYLFTPLRLDSQGTLTR
HHHHHHHHHHCCCEEECCCCCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301838; 9205837; 9278503; 10954745; 2204419; 1522592; 1631098; 9698564; 10606510 [H]