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The map label for this gene is apbE [H]

Identifier: 182682163

GI number: 182682163

Start: 1821216

End: 1822196

Strand: Direct

Name: apbE [H]

Synonym: XfasM23_1642

Alternate gene names: 182682163

Gene position: 1821216-1822196 (Clockwise)

Preceding gene: 182682162

Following gene: 182682166

Centisome position: 71.82

GC content: 55.15

Gene sequence:

>981_bases
ATGAACACACCCAACCTCAACCTTGCCACCCTGGGTGGCTACACCATGGGCACCACCTGGAGCGTGAAACTGGCTGCACC
ACGACGACTCGACCTACACCCACTACACAATGCAATCCAAGCACGACTCGACCAGATTGTCGCGGAAATGAGCACATGGG
AGCCGAACAGTCACATTAGTCGTTTCAACCGCGCACCAGTCCGCTCATGGCATCCCCTACCAAACGATTTCGACTTAGTA
CTACGTACCGCCCTGGACATCGCAATGACCAGCAACGGCGCATTTGATCCAACCGTTGGACCGTTGGTGAGGCTATGGGG
CTTCGGTGCCTACAGCGGCAATCACAAACAAATACCAACACCTGAAGCAATCACTCTGGCAACAACACGCGTAGGCTGGC
AACACCTGGAGCGCACCACTGACGGACATTGGCTGCAACCTGGTGGAACCGAACTTGACCTATCAGCAATCGCCAAGGGA
TATAGCGTGGACGCCGTCGCCGCCACACTACATGCCAAAGGCGTGGAACATGCGTTAGTAGACATTGGAGGCGAGTTATA
TGGCTATGGACATAAACCTGACGGCACCCCTTGGAGTGTCCTGGTAGAAATGGATCTCACACACCAATATGGCAATCCAC
TGCCACCGTGCATCCTACAACTGGATGGACTTGCAGTCGCCACCTCTGGGGACCGCTGGCACCACTTCGAACACGAAGGT
CAACGCTACACACACACTATCGACCCTCACCAAGGCACCCCTATCCCTGACGCACCTGCACTAGTCACCATGATCGCAAG
CAGTGCAATGCACGCCGATGCCTGGGCAACCGCTCTAAACACGCTAGGCCGCGAAGCCGGCTTGGCACTAGCCAACACAC
TCGGATTAGCGGTTCGCTATCTAGAACACAACAATGACGCATTCACCGCTTACTACAGTCCTGCCTTCACTCGCTTGCTA
CACAAACCAGCAACAGCATGA

Upstream 100 bases:

>100_bases
ATACATGGCCACCCTAGAAGTGCTACCACAGTGACCCCTTCGCTATGACAGCCCCATCGCTTCTATAACAACCGTCTCAT
CACCTGCTTGTCACACCCGC

Downstream 100 bases:

>100_bases
ATCGGGCTGGACAGAGTCACATACTGCTATGGCTAGCATCCAACCTTCAACAGTCGTAATAATGGCGCTACTAGACCTAC
ATATCGGCCCGTGATCACTT

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNTPNLNLATLGGYTMGTTWSVKLAAPRRLDLHPLHNAIQARLDQIVAEMSTWEPNSHISRFNRAPVRSWHPLPNDFDLV
LRTALDIAMTSNGAFDPTVGPLVRLWGFGAYSGNHKQIPTPEAITLATTRVGWQHLERTTDGHWLQPGGTELDLSAIAKG
YSVDAVAATLHAKGVEHALVDIGGELYGYGHKPDGTPWSVLVEMDLTHQYGNPLPPCILQLDGLAVATSGDRWHHFEHEG
QRYTHTIDPHQGTPIPDAPALVTMIASSAMHADAWATALNTLGREAGLALANTLGLAVRYLEHNNDAFTAYYSPAFTRLL
HKPATA

Sequences:

>Translated_326_residues
MNTPNLNLATLGGYTMGTTWSVKLAAPRRLDLHPLHNAIQARLDQIVAEMSTWEPNSHISRFNRAPVRSWHPLPNDFDLV
LRTALDIAMTSNGAFDPTVGPLVRLWGFGAYSGNHKQIPTPEAITLATTRVGWQHLERTTDGHWLQPGGTELDLSAIAKG
YSVDAVAATLHAKGVEHALVDIGGELYGYGHKPDGTPWSVLVEMDLTHQYGNPLPPCILQLDGLAVATSGDRWHHFEHEG
QRYTHTIDPHQGTPIPDAPALVTMIASSAMHADAWATALNTLGREAGLALANTLGLAVRYLEHNNDAFTAYYSPAFTRLL
HKPATA
>Mature_326_residues
MNTPNLNLATLGGYTMGTTWSVKLAAPRRLDLHPLHNAIQARLDQIVAEMSTWEPNSHISRFNRAPVRSWHPLPNDFDLV
LRTALDIAMTSNGAFDPTVGPLVRLWGFGAYSGNHKQIPTPEAITLATTRVGWQHLERTTDGHWLQPGGTELDLSAIAKG
YSVDAVAATLHAKGVEHALVDIGGELYGYGHKPDGTPWSVLVEMDLTHQYGNPLPPCILQLDGLAVATSGDRWHHFEHEG
QRYTHTIDPHQGTPIPDAPALVTMIASSAMHADAWATALNTLGREAGLALANTLGLAVRYLEHNNDAFTAYYSPAFTRLL
HKPATA

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=318, Percent_Identity=33.3333333333333, Blast_Score=171, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 35509; Mature: 35509

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPNLNLATLGGYTMGTTWSVKLAAPRRLDLHPLHNAIQARLDQIVAEMSTWEPNSHIS
CCCCCCEEEEECCEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
RFNRAPVRSWHPLPNDFDLVLRTALDIAMTSNGAFDPTVGPLVRLWGFGAYSGNHKQIPT
HHCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
PEAITLATTRVGWQHLERTTDGHWLQPGGTELDLSAIAKGYSVDAVAATLHAKGVEHALV
CCEEEEEEHHHHHHHHHHCCCCCEECCCCCEEEHHHHHCCCCHHHHHHHHHHCCHHHHHH
DIGGELYGYGHKPDGTPWSVLVEMDLTHQYGNPLPPCILQLDGLAVATSGDRWHHFEHEG
HCCCHHEECCCCCCCCCEEEEEEEEEHHHCCCCCCHHHEEECCEEEEECCCCCCCCCCCC
QRYTHTIDPHQGTPIPDAPALVTMIASSAMHADAWATALNTLGREAGLALANTLGLAVRY
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LEHNNDAFTAYYSPAFTRLLHKPATA
EECCCCEEEEEECHHHHHHHHCCCCC
>Mature Secondary Structure
MNTPNLNLATLGGYTMGTTWSVKLAAPRRLDLHPLHNAIQARLDQIVAEMSTWEPNSHIS
CCCCCCEEEEECCEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
RFNRAPVRSWHPLPNDFDLVLRTALDIAMTSNGAFDPTVGPLVRLWGFGAYSGNHKQIPT
HHCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
PEAITLATTRVGWQHLERTTDGHWLQPGGTELDLSAIAKGYSVDAVAATLHAKGVEHALV
CCEEEEEEHHHHHHHHHHCCCCCEECCCCCEEEHHHHHCCCCHHHHHHHHHHCCHHHHHH
DIGGELYGYGHKPDGTPWSVLVEMDLTHQYGNPLPPCILQLDGLAVATSGDRWHHFEHEG
HCCCHHEECCCCCCCCCEEEEEEEEEHHHCCCCCCHHHEEECCEEEEECCCCCCCCCCCC
QRYTHTIDPHQGTPIPDAPALVTMIASSAMHADAWATALNTLGREAGLALANTLGLAVRY
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LEHNNDAFTAYYSPAFTRLLHKPATA
EECCCCEEEEEECHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]