Click here to switch to the map view.

The map label for this gene is gpsA

Identifier: 182681671

GI number: 182681671

Start: 1276893

End: 1277933

Strand: Reverse

Name: gpsA

Synonym: XfasM23_1129

Alternate gene names: 182681671

Gene position: 1277933-1276893 (Counterclockwise)

Preceding gene: 182681672

Following gene: 182681669

Centisome position: 50.4

GC content: 51.1

Gene sequence:

>1041_bases
ATGATCAATTCTAAGCAGAAAATTGCCGTTCTTGGTGCCGGCTCTTGGGGAACTGCTCTTGCGGCATTGGTTGCGAGGCA
TGACTATCCGACCATATTGTGGGGTCGTGATGTGCGAGTGATACAGAGCATTGATATCCAGCACCAGAACTTCCGTTATT
TACCTAGCATTATGCTTCCTCAGACGCTGCGTGCCACTACCGATTTGGCTGCAGCGGTCTCAGGTGCCGACTGGGTTTTG
GTGGCGGTTCCCTCTTACGCCTTCACTGAAACTCTATGTCGATTGGCTCCATTGCTGTCAATCGGCGTTGGTGTTGCTTG
GGCAACCAAAGGATTTGAACCGGGGTCTGGTCGTTTCCTACACGAGGTGGCTCGTGAAATCCTGGGAGGTGATGCACCAT
TGGCAGTGGTGACGGGTCCTTCTTTTGCTAAAGAAGTGACTCTGGGCCTGCCTACAGCGGTCACCGTACATGGTGAAGAT
GCGTGTTTTACTCAGATGGTGGCCAATGCGATGCATGGCCCGATGTTCCGTGCCTATACCGGCAACGACGTGATTGGTGC
TGAGCTTGGTGGGGCAATGAAGAACGTACTGGCAGTGGCTATTGGCGTGGCTGATGGCATGCAGTTAGGCATGAACGCGC
GTGCTGGTTTAATTACTCGTGGACTGAATGAAATGTTACGTTTGTCTGCGGTTATCGGTGCTCGGCCGGAAACGCTAATG
GGGTTGGCTGGTCTCGGTGATCTAGTATTGACTTGTACTGGTGACTTGTCGCGTAATCGTCGCCTAGGCTTTGCTCTGGG
GCGAGGACAGAGTTTGTCGGATGCAATACGTGAGATTGGTCAAGTCGTTGAGTCTGTACAAACTTCCGACGAGGTAATGC
GCCATGCTGAACAGAATGGTGTCGAGTTGCCGATTTCCGAAGCTGTGCGTGCTGTTCTACGTGAAGAGATAACTCCATAT
GCTGGGATGAAAGTCTTGCTTGCACGAGAGCAAAAGCCTGAATATCTTGATATTCTGTTTAAGGCAAACTGTTCTTTATA
A

Upstream 100 bases:

>100_bases
ACGCTGAAACCCTCCGCCAACGTGCTCAAAATGAAAAGGAAGGTTCGCAGATCAGTTCCCAGCCAGCTGGTAACGCTTAG
TTTTGGTGAATGTTACAAGG

Downstream 100 bases:

>100_bases
GATCTGGTCACTCTAGCTTTAAGCGGCGGATCATGAACCTACACAGCCCGCCTATGGCACAAAAGCCCGATCCATCGGAT
GGATCGGGCTGTGATATGTG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MINSKQKIAVLGAGSWGTALAALVARHDYPTILWGRDVRVIQSIDIQHQNFRYLPSIMLPQTLRATTDLAAAVSGADWVL
VAVPSYAFTETLCRLAPLLSIGVGVAWATKGFEPGSGRFLHEVAREILGGDAPLAVVTGPSFAKEVTLGLPTAVTVHGED
ACFTQMVANAMHGPMFRAYTGNDVIGAELGGAMKNVLAVAIGVADGMQLGMNARAGLITRGLNEMLRLSAVIGARPETLM
GLAGLGDLVLTCTGDLSRNRRLGFALGRGQSLSDAIREIGQVVESVQTSDEVMRHAEQNGVELPISEAVRAVLREEITPY
AGMKVLLAREQKPEYLDILFKANCSL

Sequences:

>Translated_346_residues
MINSKQKIAVLGAGSWGTALAALVARHDYPTILWGRDVRVIQSIDIQHQNFRYLPSIMLPQTLRATTDLAAAVSGADWVL
VAVPSYAFTETLCRLAPLLSIGVGVAWATKGFEPGSGRFLHEVAREILGGDAPLAVVTGPSFAKEVTLGLPTAVTVHGED
ACFTQMVANAMHGPMFRAYTGNDVIGAELGGAMKNVLAVAIGVADGMQLGMNARAGLITRGLNEMLRLSAVIGARPETLM
GLAGLGDLVLTCTGDLSRNRRLGFALGRGQSLSDAIREIGQVVESVQTSDEVMRHAEQNGVELPISEAVRAVLREEITPY
AGMKVLLAREQKPEYLDILFKANCSL
>Mature_346_residues
MINSKQKIAVLGAGSWGTALAALVARHDYPTILWGRDVRVIQSIDIQHQNFRYLPSIMLPQTLRATTDLAAAVSGADWVL
VAVPSYAFTETLCRLAPLLSIGVGVAWATKGFEPGSGRFLHEVAREILGGDAPLAVVTGPSFAKEVTLGLPTAVTVHGED
ACFTQMVANAMHGPMFRAYTGNDVIGAELGGAMKNVLAVAIGVADGMQLGMNARAGLITRGLNEMLRLSAVIGARPETLM
GLAGLGDLVLTCTGDLSRNRRLGFALGRGQSLSDAIREIGQVVESVQTSDEVMRHAEQNGVELPISEAVRAVLREEITPY
AGMKVLLAREQKPEYLDILFKANCSL

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=335, Percent_Identity=29.5522388059701, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI24307999, Length=337, Percent_Identity=28.1899109792285, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1790037, Length=335, Percent_Identity=45.6716417910448, Blast_Score=290, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI32564399, Length=361, Percent_Identity=26.5927977839335, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI32564403, Length=370, Percent_Identity=26.7567567567568, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193210136, Length=370, Percent_Identity=26.7567567567568, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17507425, Length=363, Percent_Identity=25.8953168044077, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193210134, Length=340, Percent_Identity=24.7058823529412, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324513, Length=346, Percent_Identity=29.4797687861272, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320181, Length=337, Percent_Identity=28.486646884273, Blast_Score=109, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17136200, Length=361, Percent_Identity=26.3157894736842, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI17136202, Length=343, Percent_Identity=26.8221574344023, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136204, Length=343, Percent_Identity=26.8221574344023, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI22026922, Length=295, Percent_Identity=29.1525423728814, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI281362270, Length=239, Percent_Identity=31.3807531380753, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45551945, Length=239, Percent_Identity=31.3807531380753, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648969, Length=227, Percent_Identity=30.3964757709251, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_XYLF2 (B2I5B4)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829831.1
- ProteinModelPortal:   B2I5B4
- GeneID:   6202617
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1129
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36803; Mature: 36803

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 194-194 BINDING 110-110 BINDING 110-110 BINDING 143-143 BINDING 258-258 BINDING 284-284

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSKQKIAVLGAGSWGTALAALVARHDYPTILWGRDVRVIQSIDIQHQNFRYLPSIMLP
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCEEEEHHCCCCCCCCHHCCHHHCC
QTLRATTDLAAAVSGADWVLVAVPSYAFTETLCRLAPLLSIGVGVAWATKGFEPGSGRFL
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHH
HEVAREILGGDAPLAVVTGPSFAKEVTLGLPTAVTVHGEDACFTQMVANAMHGPMFRAYT
HHHHHHHHCCCCCEEEEECCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEC
GNDVIGAELGGAMKNVLAVAIGVADGMQLGMNARAGLITRGLNEMLRLSAVIGARPETLM
CCCEEHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
GLAGLGDLVLTCTGDLSRNRRLGFALGRGQSLSDAIREIGQVVESVQTSDEVMRHAEQNG
HHHCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VELPISEAVRAVLREEITPYAGMKVLLAREQKPEYLDILFKANCSL
CCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MINSKQKIAVLGAGSWGTALAALVARHDYPTILWGRDVRVIQSIDIQHQNFRYLPSIMLP
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCEEEEHHCCCCCCCCHHCCHHHCC
QTLRATTDLAAAVSGADWVLVAVPSYAFTETLCRLAPLLSIGVGVAWATKGFEPGSGRFL
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHH
HEVAREILGGDAPLAVVTGPSFAKEVTLGLPTAVTVHGEDACFTQMVANAMHGPMFRAYT
HHHHHHHHCCCCCEEEEECCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEC
GNDVIGAELGGAMKNVLAVAIGVADGMQLGMNARAGLITRGLNEMLRLSAVIGARPETLM
CCCEEHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
GLAGLGDLVLTCTGDLSRNRRLGFALGRGQSLSDAIREIGQVVESVQTSDEVMRHAEQNG
HHHCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VELPISEAVRAVLREEITPYAGMKVLLAREQKPEYLDILFKANCSL
CCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA