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The map label for this gene is yjcE [H]

Identifier: 182681391

GI number: 182681391

Start: 993657

End: 995357

Strand: Direct

Name: yjcE [H]

Synonym: XfasM23_0840

Alternate gene names: 182681391

Gene position: 993657-995357 (Clockwise)

Preceding gene: 182681390

Following gene: 182681392

Centisome position: 39.19

GC content: 51.03

Gene sequence:

>1701_bases
ATGTTGGCGGCTGCTATGCGTGGTATGGCTGTGACATTTTTTTCACAATTCATGGTTTCTTGCATGCATTCGATTCAAAT
CGTTCTTGCGATGTTGCTAGTCGTGGCAGCCAGTGGTTACCTGGTACGTATTATTCCATTTTCAATGCCGTTGCCTTTGT
TGCAGATTGCGCTTGGTGCGGTGATCTCTGGTGTCTTTGATGGTGGTTATGAGTTACAGCCTGAGGCGTTTTTCTTACTG
TTTTTGCCGCCGCTACTGTTTTTGGATGGTTGGCGCATTCCTAAGCAAGGTTTATTCCGCGATAAAAATGTGATTCTCGA
GTTAGCGCTGGGATTGGTGGTTTTTACTGTATTGGGTATCGGTTTTCTGATTCATTGGATGATTCCGACAATGCCGCTGC
CGCTGGCTTTTGCGTTGGCGGCGATTTTGTCGCCTACCGATCCTGTTGCGCTGTCTTCGATTACTTCAAGGGTGCCCATT
CCCAAGCGCATGATGCATATTTTGGAAGGCGAGTCGCTGCTTAACGATGCGACTGGGCTGGTCTGTTTCCAATTTGCAGT
TGCGGCTGTGTTGACTGGGCATTTTTCGTTGGCCACTGCTTCGCTGACTTTTGTTTGGGTGCTTGTGGTCGGTTTGAGTT
TGGGTATAGCGACAACGTATGTGCTCAGTCGAGTACAGAGGTGGGTTTGGCGTCATTTTGGCGGGGAGCCGGCGGCGGCG
ATTCTGTTCAATCTGTTGACTCCTTTTGCTGCCTATCTGTTGGCTGAGAGTATGCAGGCTTCGGGAATTTTGGCGGCAGT
TGCTGCCGGAATCACGATGAGTTATGTCGAGTTGAGTGGGAATGCTCAGGCGACGATACGGGTACAGCGCTGGGCGGTGT
GGGAAACGGTGCAGTTTACTTTCAATGGCATTATTTTCGTGCTGCTCGGCGAGCAATTGCCTGGAATCCTTGATGATCTC
GTTCACAGTGCACAGCAAGCTGGGTATATGAATGTGGGATGGTTACTGGTTGACGTTGCTGTGATTAGCGCCGGATTGAT
GTTGTTGCGTTTTTTATGGGTGTGGTTGTCATTGCAGTGGAATTTGTTTAAAGCGGTGTGTTGCGGCAAGCAGCGTATCA
GTCCGCCGTGGCAGATTGTGGTGGCGATGTCGTTGTCTGGGGTGCGTGGTGCGGTTACTTTGGCCGGGGTGCTGACATTG
CCGTTGTTGATGCCGGATGGTACGCCGTTGCCGGCACGGCAGTTGGTAATCTTTTTGGCCGCCTCAGTCATTCTGGTTTC
GCTGTTACTGGCGAGTGTGGCTTTACCGTATTTGCTGCGTGGTTTGGAGCTTCCCGAGAAGAGTAGTTATGACAAGGAAG
AGGATTTCGCGCGTAGAGTATCGGCTCAGGCTGCACTTGAGGCAGTGGAGCGGCTACGTCAGAGGTTGGTTGAGGATAGT
GCTAATGCTGAGCGCTACAATGAGGCTGCTCATCAGGTCAGCCAATTGTATCAACGCAAGCTTGGGGCCGTTGATCTGGC
CAATGTCGATCCACAAGAAACCAAGGTATTCGAGCAGGTTGTACGGCGCTTTCGTCAGGTGGGTTTGGCCGCTGAGCGTG
ATGAGTTGTTTAGGTTGGCACGTGAGCACAATATTTCCGATGAGTTGTTGCAACGGATGGTGCGTAATTTGGATTTGATT
GAGGCACGCAGGCGCAGTTAG

Upstream 100 bases:

>100_bases
ATGGAGTGATATCAGTCGTGGGAATTATCTTCGGTGCAGTGGTTCAATCAGAAAGATGAATATGGTGTCATCTGAATGAT
TGGGGATAGCAGAATCGCTA

Downstream 100 bases:

>100_bases
TTGAACAGGGGGCTATGTTGGATGGAATGCATCTGTGTTGTTGCAAGGTAGTAGCGCGGAGTTTGATGTTTGAGTTGTGG
TGTCATTGGGTGCAATGGCT

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MLAAAMRGMAVTFFSQFMVSCMHSIQIVLAMLLVVAASGYLVRIIPFSMPLPLLQIALGAVISGVFDGGYELQPEAFFLL
FLPPLLFLDGWRIPKQGLFRDKNVILELALGLVVFTVLGIGFLIHWMIPTMPLPLAFALAAILSPTDPVALSSITSRVPI
PKRMMHILEGESLLNDATGLVCFQFAVAAVLTGHFSLATASLTFVWVLVVGLSLGIATTYVLSRVQRWVWRHFGGEPAAA
ILFNLLTPFAAYLLAESMQASGILAAVAAGITMSYVELSGNAQATIRVQRWAVWETVQFTFNGIIFVLLGEQLPGILDDL
VHSAQQAGYMNVGWLLVDVAVISAGLMLLRFLWVWLSLQWNLFKAVCCGKQRISPPWQIVVAMSLSGVRGAVTLAGVLTL
PLLMPDGTPLPARQLVIFLAASVILVSLLLASVALPYLLRGLELPEKSSYDKEEDFARRVSAQAALEAVERLRQRLVEDS
ANAERYNEAAHQVSQLYQRKLGAVDLANVDPQETKVFEQVVRRFRQVGLAAERDELFRLAREHNISDELLQRMVRNLDLI
EARRRS

Sequences:

>Translated_566_residues
MLAAAMRGMAVTFFSQFMVSCMHSIQIVLAMLLVVAASGYLVRIIPFSMPLPLLQIALGAVISGVFDGGYELQPEAFFLL
FLPPLLFLDGWRIPKQGLFRDKNVILELALGLVVFTVLGIGFLIHWMIPTMPLPLAFALAAILSPTDPVALSSITSRVPI
PKRMMHILEGESLLNDATGLVCFQFAVAAVLTGHFSLATASLTFVWVLVVGLSLGIATTYVLSRVQRWVWRHFGGEPAAA
ILFNLLTPFAAYLLAESMQASGILAAVAAGITMSYVELSGNAQATIRVQRWAVWETVQFTFNGIIFVLLGEQLPGILDDL
VHSAQQAGYMNVGWLLVDVAVISAGLMLLRFLWVWLSLQWNLFKAVCCGKQRISPPWQIVVAMSLSGVRGAVTLAGVLTL
PLLMPDGTPLPARQLVIFLAASVILVSLLLASVALPYLLRGLELPEKSSYDKEEDFARRVSAQAALEAVERLRQRLVEDS
ANAERYNEAAHQVSQLYQRKLGAVDLANVDPQETKVFEQVVRRFRQVGLAAERDELFRLAREHNISDELLQRMVRNLDLI
EARRRS
>Mature_566_residues
MLAAAMRGMAVTFFSQFMVSCMHSIQIVLAMLLVVAASGYLVRIIPFSMPLPLLQIALGAVISGVFDGGYELQPEAFFLL
FLPPLLFLDGWRIPKQGLFRDKNVILELALGLVVFTVLGIGFLIHWMIPTMPLPLAFALAAILSPTDPVALSSITSRVPI
PKRMMHILEGESLLNDATGLVCFQFAVAAVLTGHFSLATASLTFVWVLVVGLSLGIATTYVLSRVQRWVWRHFGGEPAAA
ILFNLLTPFAAYLLAESMQASGILAAVAAGITMSYVELSGNAQATIRVQRWAVWETVQFTFNGIIFVLLGEQLPGILDDL
VHSAQQAGYMNVGWLLVDVAVISAGLMLLRFLWVWLSLQWNLFKAVCCGKQRISPPWQIVVAMSLSGVRGAVTLAGVLTL
PLLMPDGTPLPARQLVIFLAASVILVSLLLASVALPYLLRGLELPEKSSYDKEEDFARRVSAQAALEAVERLRQRLVEDS
ANAERYNEAAHQVSQLYQRKLGAVDLANVDPQETKVFEQVVRRFRQVGLAAERDELFRLAREHNISDELLQRMVRNLDLI
EARRRS

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI41872703, Length=556, Percent_Identity=23.7410071942446, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI148727259, Length=443, Percent_Identity=23.0248306997743, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI27777632, Length=370, Percent_Identity=28.3783783783784, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI15529998, Length=447, Percent_Identity=23.489932885906, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI4759144, Length=367, Percent_Identity=28.3378746594005, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI14211919, Length=257, Percent_Identity=27.2373540856031, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI27734935, Length=345, Percent_Identity=20.8695652173913, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI110227626, Length=260, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI294997330, Length=260, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI5454070, Length=260, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1790501, Length=543, Percent_Identity=42.1731123388582, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI25150332, Length=396, Percent_Identity=26.7676767676768, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71987535, Length=499, Percent_Identity=23.4468937875752, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71987537, Length=499, Percent_Identity=23.4468937875752, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71987559, Length=415, Percent_Identity=23.6144578313253, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71999819, Length=567, Percent_Identity=22.2222222222222, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71999817, Length=567, Percent_Identity=22.2222222222222, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71987545, Length=331, Percent_Identity=25.3776435045317, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71999821, Length=536, Percent_Identity=22.7611940298507, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71993590, Length=415, Percent_Identity=26.7469879518072, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71993582, Length=415, Percent_Identity=26.7469879518072, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71980847, Length=525, Percent_Identity=21.7142857142857, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71992101, Length=254, Percent_Identity=24.4094488188976, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71992107, Length=254, Percent_Identity=24.4094488188976, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25147678, Length=417, Percent_Identity=24.220623501199, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=252, Percent_Identity=26.5873015873016, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221473222, Length=424, Percent_Identity=22.1698113207547, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281364513, Length=424, Percent_Identity=22.1698113207547, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221473215, Length=419, Percent_Identity=22.4343675417661, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221473212, Length=402, Percent_Identity=22.1393034825871, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221510738, Length=515, Percent_Identity=23.8834951456311, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221510734, Length=388, Percent_Identity=26.0309278350515, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221510732, Length=384, Percent_Identity=26.0416666666667, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI221510736, Length=384, Percent_Identity=26.0416666666667, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24585580, Length=384, Percent_Identity=26.0416666666667, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24585578, Length=384, Percent_Identity=26.0416666666667, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221510740, Length=384, Percent_Identity=26.0416666666667, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281360447, Length=532, Percent_Identity=23.4962406015038, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 62333; Mature: 62333

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MLAAAMRGMAVTFFSQFMVSCMHSIQIVLAMLLVVAASGYLVRIIPFSMPLPLLQIALGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHH
VISGVFDGGYELQPEAFFLLFLPPLLFLDGWRIPKQGLFRDKNVILELALGLVVFTVLGI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
GFLIHWMIPTMPLPLAFALAAILSPTDPVALSSITSRVPIPKRMMHILEGESLLNDATGL
HHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHH
VCFQFAVAAVLTGHFSLATASLTFVWVLVVGLSLGIATTYVLSRVQRWVWRHFGGEPAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ILFNLLTPFAAYLLAESMQASGILAAVAAGITMSYVELSGNAQATIRVQRWAVWETVQFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEHHHHHHHHHHH
FNGIIFVLLGEQLPGILDDLVHSAQQAGYMNVGWLLVDVAVISAGLMLLRFLWVWLSLQW
HCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLFKAVCCGKQRISPPWQIVVAMSLSGVRGAVTLAGVLTLPLLMPDGTPLPARQLVIFLA
HHHHHHHHCCCCCCCCHHEEEEHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ASVILVSLLLASVALPYLLRGLELPEKSSYDKEEDFARRVSAQAALEAVERLRQRLVEDS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANAERYNEAAHQVSQLYQRKLGAVDLANVDPQETKVFEQVVRRFRQVGLAAERDELFRLA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
REHNISDELLQRMVRNLDLIEARRRS
HHCCCHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]