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The map label for this gene is gltA

Identifier: 182681340

GI number: 182681340

Start: 933968

End: 935257

Strand: Direct

Name: gltA

Synonym: XfasM23_0787

Alternate gene names: 182681340

Gene position: 933968-935257 (Clockwise)

Preceding gene: 182681339

Following gene: 182681343

Centisome position: 36.83

GC content: 47.6

Gene sequence:

>1290_bases
ATGTCCGATCTTGATAAGGTCACGCTCAATGCTGGTGAGACTTCTCTCGTTTTACCGGTTTTGAAACCCACGTTAGGTAA
TGGTTGCGTTGATATTGCCAAGTTGACAAAGGAAACCGGGCTGTTTACTTACGACTCTGGTTTTACGGCAACTGCAAGCT
GTAAGTCTGCCATCACTTACATTGATGGTGAAAAGGGTGTGTTGTTGTACCGCGGCTATCCGATTGAGCAGTTAGCCGAG
CACTCCAGTTTTTTGGAGGTCGCTTATTTGTTGATGAACGGTGAGTTACCGAGAAAAGACGAGTTTGCCAAGTTTGATGA
TGAAATTACGCATCACACGATGATGCATGAGTCGTTGAAGAACTTTCTTGGCGGTTTTCATTATGATGCACATCCAATGG
CTATGTTGGCTGCTTCGGTGGCTTCGCTGTCGGCGTTCTACCACGATACCCTTGATTTGAACGATCTTGAGCAACGTCGC
TTAGCTGCAATTCGTTTGATCGCTAAGGTGCCGACGCTTGCAGCGGCAGCGCATCGCTACTCGATTGGCTGGCCGATCCG
TTATCCACGAAACAATCTTGGTTATGTCGAGCGCTTTTTGCATATGATGTTTGAAGTGCCTAGTGAACCGCTGCAGTTGA
ATCCAGTCGTGATCAAAGCTCTGGATTTACTGTTTATTTTGCATGCTGATCATGAGCAGAACGCTTCGACATCAACAGTC
CGTTTGGTGGGTTCGACTGGCGCTAATCCTTATGCATCGGTTGCCGCGGGTATCACCGCGTTGTGGGGACCGGCACACGG
CGGCGCTAATGAGGCCGTGTTAAAGATGTTGGAGGAGATTGGTGATGCTAAGAATGTTGACTTGGTTATTGCAAAAGCGA
AAACCAAGGACAAAAACTCTCCATTCCGTTTGATGGGTTTCGGCCATCGTGTCTATAAACATTTTGATCCACGTGCGAAA
ATCATCCGTGAGATGGCACACACAGTTCTTGGTGAGTTAGGTGTGAACGATCCGCTACTGGAAGTAGCATTAAAGTTGGA
AGAGGCAGCGCTGAAGGATGATTACTTTGTGCAGCGTAAGTTGTACCCTAACGTTGATTTTTATTCGGGCATCATCTACA
AAGCCATCAACATTCCTTTGGAAATGTTTACAGTGATGTTTGCCATCGCGCGTACCGCAGGGTGGGTTTCTCATTGGCTT
GAGCAGCAAGTCGACCCGGAGATGAAAATCAGCAGGCCGCGCCAAATTTACACAGGTCATCGCGAGCGTGACTACAAAGA
TGCTAGGTAA

Upstream 100 bases:

>100_bases
GGATGTCTGTAATAGCTCAAGCGCATTATTCTTTGATACCTAACAACCGCCCTTACGGTTTGCCGTTTGGGCGTCTTTCC
ATTGTTAAGGAGCCCACGCT

Downstream 100 bases:

>100_bases
GGGTAAAGAGACTCTTACATCTTCCAATGTGCTTATCAGATGAAGGCCCTATTGTGGATGTCTGACAGCAACCGCGCGTA
ATAACGCGAATAGAGTCACC

Product: type II citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSDLDKVTLNAGETSLVLPVLKPTLGNGCVDIAKLTKETGLFTYDSGFTATASCKSAITYIDGEKGVLLYRGYPIEQLAE
HSSFLEVAYLLMNGELPRKDEFAKFDDEITHHTMMHESLKNFLGGFHYDAHPMAMLAASVASLSAFYHDTLDLNDLEQRR
LAAIRLIAKVPTLAAAAHRYSIGWPIRYPRNNLGYVERFLHMMFEVPSEPLQLNPVVIKALDLLFILHADHEQNASTSTV
RLVGSTGANPYASVAAGITALWGPAHGGANEAVLKMLEEIGDAKNVDLVIAKAKTKDKNSPFRLMGFGHRVYKHFDPRAK
IIREMAHTVLGELGVNDPLLEVALKLEEAALKDDYFVQRKLYPNVDFYSGIIYKAINIPLEMFTVMFAIARTAGWVSHWL
EQQVDPEMKISRPRQIYTGHRERDYKDAR

Sequences:

>Translated_429_residues
MSDLDKVTLNAGETSLVLPVLKPTLGNGCVDIAKLTKETGLFTYDSGFTATASCKSAITYIDGEKGVLLYRGYPIEQLAE
HSSFLEVAYLLMNGELPRKDEFAKFDDEITHHTMMHESLKNFLGGFHYDAHPMAMLAASVASLSAFYHDTLDLNDLEQRR
LAAIRLIAKVPTLAAAAHRYSIGWPIRYPRNNLGYVERFLHMMFEVPSEPLQLNPVVIKALDLLFILHADHEQNASTSTV
RLVGSTGANPYASVAAGITALWGPAHGGANEAVLKMLEEIGDAKNVDLVIAKAKTKDKNSPFRLMGFGHRVYKHFDPRAK
IIREMAHTVLGELGVNDPLLEVALKLEEAALKDDYFVQRKLYPNVDFYSGIIYKAINIPLEMFTVMFAIARTAGWVSHWL
EQQVDPEMKISRPRQIYTGHRERDYKDAR
>Mature_428_residues
SDLDKVTLNAGETSLVLPVLKPTLGNGCVDIAKLTKETGLFTYDSGFTATASCKSAITYIDGEKGVLLYRGYPIEQLAEH
SSFLEVAYLLMNGELPRKDEFAKFDDEITHHTMMHESLKNFLGGFHYDAHPMAMLAASVASLSAFYHDTLDLNDLEQRRL
AAIRLIAKVPTLAAAAHRYSIGWPIRYPRNNLGYVERFLHMMFEVPSEPLQLNPVVIKALDLLFILHADHEQNASTSTVR
LVGSTGANPYASVAAGITALWGPAHGGANEAVLKMLEEIGDAKNVDLVIAKAKTKDKNSPFRLMGFGHRVYKHFDPRAKI
IREMAHTVLGELGVNDPLLEVALKLEEAALKDDYFVQRKLYPNVDFYSGIIYKAINIPLEMFTVMFAIARTAGWVSHWLE
QQVDPEMKISRPRQIYTGHRERDYKDAR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=325, Percent_Identity=28.6153846153846, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1786939, Length=421, Percent_Identity=57.4821852731591, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1786527, Length=387, Percent_Identity=30.2325581395349, Blast_Score=171, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI17555174, Length=385, Percent_Identity=25.4545454545455, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325257, Length=406, Percent_Identity=26.8472906403941, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6319850, Length=347, Percent_Identity=25.9365994236311, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324328, Length=324, Percent_Identity=27.4691358024691, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24640126, Length=392, Percent_Identity=27.0408163265306, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24640124, Length=392, Percent_Identity=27.0408163265306, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356863, Length=353, Percent_Identity=26.628895184136, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 47981; Mature: 47850

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLDKVTLNAGETSLVLPVLKPTLGNGCVDIAKLTKETGLFTYDSGFTATASCKSAITY
CCCCCCEEECCCCCEEEEHHHCCCCCCCHHHHHHHHHHCCCEEECCCCEEHHHHHHCEEE
IDGEKGVLLYRGYPIEQLAEHSSFLEVAYLLMNGELPRKDEFAKFDDEITHHTMMHESLK
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
NFLGGFHYDAHPMAMLAASVASLSAFYHDTLDLNDLEQRRLAAIRLIAKVPTLAAAAHRY
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SIGWPIRYPRNNLGYVERFLHMMFEVPSEPLQLNPVVIKALDLLFILHADHEQNASTSTV
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCEE
RLVGSTGANPYASVAAGITALWGPAHGGANEAVLKMLEEIGDAKNVDLVIAKAKTKDKNS
EEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
PFRLMGFGHRVYKHFDPRAKIIREMAHTVLGELGVNDPLLEVALKLEEAALKDDYFVQRK
CEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHH
LYPNVDFYSGIIYKAINIPLEMFTVMFAIARTAGWVSHWLEQQVDPEMKISRPRQIYTGH
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCC
RERDYKDAR
CCCCCCCCC
>Mature Secondary Structure 
SDLDKVTLNAGETSLVLPVLKPTLGNGCVDIAKLTKETGLFTYDSGFTATASCKSAITY
CCCCCEEECCCCCEEEEHHHCCCCCCCHHHHHHHHHHCCCEEECCCCEEHHHHHHCEEE
IDGEKGVLLYRGYPIEQLAEHSSFLEVAYLLMNGELPRKDEFAKFDDEITHHTMMHESLK
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
NFLGGFHYDAHPMAMLAASVASLSAFYHDTLDLNDLEQRRLAAIRLIAKVPTLAAAAHRY
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SIGWPIRYPRNNLGYVERFLHMMFEVPSEPLQLNPVVIKALDLLFILHADHEQNASTSTV
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCEE
RLVGSTGANPYASVAAGITALWGPAHGGANEAVLKMLEEIGDAKNVDLVIAKAKTKDKNS
EEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
PFRLMGFGHRVYKHFDPRAKIIREMAHTVLGELGVNDPLLEVALKLEEAALKDDYFVQRK
CEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHH
LYPNVDFYSGIIYKAINIPLEMFTVMFAIARTAGWVSHWLEQQVDPEMKISRPRQIYTGH
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCC
RERDYKDAR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2507528; 10984043 [H]